• Bulletin of the Korean Chemical Society
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• v.31 no.11
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• pp.3291-3296
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• 2010

A gelastatins (1), natural MMP inhibitors, and their hydroxamate analogues (2) in TACE enzyme evaluated for discovery of potent TACE inhibitors. We have employed molecular dynamics simulations to compute the relative free energy of hydration and binding to TACE for gelastatin (1) and its hydroxamate analogue (2). The relative free energy difference is directly described in this article using the free energy perturbation approach as a means to accurately predict the TACE inhibitor of gelastatin analogues. The results show that the good agreement between the experimental and theoretical relative free energies of binding, gelastatin hydroxamate (2) binds stronger to TACE by -3.37 kcal/mol. The desolvation energy costs significantly reduced binding affinity, hydroxamate group associated with high desolvation energy formed strong favorable interactions with TACE with more than compensated for the solvation costs and therefore led to an improvement in relative binding affinity.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.17 no.4
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• pp.61-74
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• 2007

In Common Criteria evaluation scheme, sponsor and evaluator should estimate evaluation cost and duration of IT security system evaluation in contracting the evaluation project. In this paper, We analyzed study result that achieve at 2003 and 2005, and utilized part of study result. And we empirically estimate relative evaluation effort ratios among evaluation assurance levels($EAL1{\sim}EAL7$) in CC v2.3 and CC v3.1. Also, we estimate the ratios from 'developer action elements', adjusted 'content and presentation of evidence elements', and 'evaluator action elements 'for each assurance component. We, especially, use ratio of amount of effort for each 'evaluator action elements', that was obtained from real evaluators in KISA in 2003. Our result will useful for TOE sponsor as well as evaluation project manager who should estimate evaluation cost and duration for a specific EAL and type of TOE, in a new CC v3.1 based evaluation schem.

• Journal of the Korean Mathematical Society
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• v.25 no.1
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• pp.149-160
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• 1988

• Journal of the Society of Naval Architects of Korea
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• v.52 no.6
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• pp.460-470
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• 2015

In general ships and FPSOs, roll damping is very small and consequently roll motion is very large at the roll resonance frequency. Proper evaluation of the roll damping coefficient at the resonance frequency is an important task in the study of roll motion and usually it is done by the analysis of free roll decay tests. The relative decrement method based on energy relation has been used mainly for the evaluation of roll damping coefficient from the roll decay test so far. As another method, the logarithmic decrement method based on equivalent linear decay assumption can be used for the same purpose and it is relatively simple. In this paper, both of the relative decrement method and the logarithmic decrement method are used for the evaluation of roll damping coefficient including quadratic damping from the free roll decay tests, and their results are cross-checked for verifying the obtained damping coefficients. Through applications to a box-type floating body equiped with bilge keels, it is shown that the two methods give almost the same damping coefficients in a practical view point and the cross-check of their results is to be a good tool to prevent a possible error. And also the quantitative effects of the bilge keels on the roll damping of box-type floating body are shown and discussed.

• The Journal of the Korea Contents Association
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• v.19 no.2
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• pp.491-507
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• 2019

The result of this study was to measure the relative efficiency of 133 colleges in south korea and to investigate the differences in the results of college basic competency evaluation. As a result of the study showed that the average difference of efficiency according to the background variables was no significant according to the scale, location, and college evaluation. but differences in the type of establishment were found to vary significantly in S.E model. In addition, it was analyzed that the efficiency of the college with limited funding for the efficiency distribution is highly distributed, which indicates that it is necessary to continuously improve the existing university methods and to assess whether they are being managed effectively. Finally, the limitations of this study are that it used only quantitative data and that additional indicators could result in different outcomes from the results of this study.

• Journal of the Ergonomics Society of Korea
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• v.26 no.4
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• pp.57-64
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• 2007

In the world, the old population is growing fast and many countries went into an advanced age society. Therefore the development of everyday products, electric appliances, and welfare services considering old people is more important than ever. In particular, the complexity of products can cause many problems for old people. Universal design is an approach to create environments and products that recognizes the diversity of users, regardless of their ability or age. Universality evaluation for a product is very important to verify old people's accessibility and usability for the product. Universality means how good a product was designed in view of universal design principles. In this study, UNIX, a method to evaluate the universality of a product was developed. UNIX was based on seven universal design principles; equitable use, flexibility in use, simple and intuitive, perceptible information, tolerance for error, low physical effort, size and space for approach and use. UNIX is a kind of expert evaluation and very simple method. The method is consisted of two steps. In the first step, relative weights for seven principles and subjective ratings on design suitability for each principle are obtained. In the second step, universality index (UNIX) of each product is obtained by weighted average multiplying relative weights and rating scores. As a case study, this method was applied for mouse designs. In conclusion, this method could be effectively applied to evaluate the universality of a product.

• Korean Institute of Interior Design Journal
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• v.20 no.5
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• pp.34-41
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• 2011

Today, residential building is considered of be one of the most important space of their quality of life and health. Residential buildings should provide comfortable environments to support the activities of their occupants. And good residential buildings are made by appropriately combining residential spaces, such as living room, master bedroom, bedroom, kitchen, restroom, and so on. These combinations in residential building are must be compatible with the activities of the occupants and their needs. The objective of this research is to investigate and analyze the relative importance and space priority between residential space in residential buildings depending on occupants' characteristics, such as, gender and age. Especially, this research is to find space weighting factors for integrative evaluation in residential buildings based on occupant survey. These weighting factors play an important role in determining the relative importance of various residential spaces for integrative residential space evaluation. And, the result from this research will help designers and researchers to find space planning strategies in residential building, and develop new integrative evaluation framework for improving residential quality from the occupants' point of view.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.1132-1140
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• 2009

Recently soil improvement methods are using in many ways such as costal and soft ground of inland. Among them, sand compaction pile be widely used because of quiet few advantages. There are two ways for quality evaluation method of sand compaction pile. Especially standard penetration test is used the most general method. However, Current method have problems in that it is not consider the condition of construction site. Therefore this study is propose new quality evaluation method. Relation of N-$\Phi$ is always not fixed but changing by condition of construction site. By through the Laboratory test we can know relationship between relative density and internal friction. Also this study propose revision for effective stress. From these study, we can acquire more accurate and reasonable result than current method.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.41 no.3
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• pp.257-265
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• 2021

In this study, an evaluation index was developed and applied to derive indicators related to the environment for bicycle use and to evaluate the environment for bicycle use in the city of Suwon. Analysis showed that the relative importance between the assessment factors was highest in bicycle safety and that the relative importance among the assessment indicators was highest in terms of priority of items directly affecting bike riding, and items with indirect influence were low in importance. As a result of applying the evaluation model to bike paths in Suwon, it was confirmed that they can be described in a relatively realistic manner. The findings are expected to contribute to the development of local government directives for improving the environment of cycle paths.

• Journal of the Korean Operations Research and Management Science Society
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• v.32 no.2
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• pp.123-140
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• 2007

This study focuses on establishing theoretically-reasonable framework of evaluation areas and items for the informatization program and analyzing the weights for each area and item by means of the AHP. To obtain the goal of this research, firstly, based on broadly reviewing previous literature and logical reasoning, the evaluation criteria were Identified and conceptualized, which were 3 evaluation phases, 5 evaluation areas, and 22 evaluation items. Secondly, The data used for calculating the weight values for the evaluation criteria were collected from 48 academic and practical experts in the field of the informatization program promotion using internet survey. Thirdly, the relative weights among evaluation phases, evaluation areas, and its items were derived by AHP analysis. The findings of this study are thought not only to be useful as a practical guideline in performing evaluating the informatization program but also to provide significant basis for constructing the theoretical framework of evaluating method and management of the informatization program.