• 제목/요약/키워드: Related Studies

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혈전증(血栓症) 및 고점도혈증(高粘度血症)에 대(對)한 당귀음(當歸飮)과 이진탕(二陳湯)의 실험적(實驗的) 연구(硏究) (Studies on the Effects of Danggieum and Ijintang on Thrombosis and Elevated Blood Viscosity)

  • 김영석
    • 대한한의학회지
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    • 제15권2호
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    • pp.212-232
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    • 1994
  • I selected the theory of blood stasis and wetness-phlegm among the major 4 causes of Joong Poong(C.V.A.)(wind. fire. deficiency of vital energy and wetness-phlegm) and recent etiology of blood stasis. An experimental studies were done to investigate the effects of Danggieum (removing blood stasis and promoting blood circulation) and Ijintang(dissipating wetness-phlegm) on thrombosis and elevated blood viscosity. The results were as follows; 1. The number of platelets were significantly increased in only Danggieum group. 2. Related to the amount of fibrinogen. only Danggieum group revealed some increase. but both groups revealed no significance. 3. Related to the prothrombin time. Danggieum and Ijintang groups had significant decrease. but Danggieum group revealed more significance. 4. Related to the degree of concentration of FDP, only Danggieum group had significant decrease. 5. Whole blood viscosity and plasma viscosity in lower shear rates. both groups of Danggieum and Ijintang had significant decrease. 6. Related to the amount of RBC. both groups of Danggieum and Ijintang had significant decrease. 7. Related to the change of hematocrit. only Danggieum group, and the change of hemoglobin. only Ijintang group had significant decrease. 8. Related to the change of body temperature. only Ijintang group had significant raise. 9. Related to the changes of WBC. glucose, albumin, total protein and body weight. Danggieum and Ijintang groups had each increase or decrease. but no significance. According to the above results, Danggieum had more significant effect than Ijintang on the thrombosis. and Ijintang had more significant effect than Danggieum on the elevated blood viscosity. And it is considered that it might be more effective in treating Joong-Poong(C.V.A) to take medicines regarding patient's constitution and symptoms as well as the causes of Joong-Poong(C.V.A)

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아동의 자기효능감 및 아동이 지각한 부모의 양육태도와 창의성과의 관계 (Relationships between Children's Self-Efficacy, Parental Child-Rearing Attitude Perceived by the Child and Creativity)

  • 장혜선;최보가
    • 대한가정학회지
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    • 제43권3호
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    • pp.59-73
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    • 2005
  • The purpose of this study was to investigate the relationships between children's self-efficacy, parental child-rearing attitude perceived by the child, and creativity. The study subjects were 120 5th and 6th graders at elementary school in Gyeongbuk. The instruments of measurement were question sheets, Self-Efficacy Scale, and Parental child-rearing attitude Scale. For creative thinking tests, the Kim Yong-Chae version of TTCT (Torrance Test of Creative Thinking) was used. The data were analysed through mean, standard deviation, frequency, percentile, Cronbach's $\alpha$, and Pearson's Correlation Coefficient. The major findings of this study were as follows: First, the results from the correlational analysis didn't yield significant and meaningful correlations between children's self-efficacy and thinking creatively with words. Nevertheless, children's self-efficacy was partly related to thinking creatively with pictures. Second, the results from the correlational analysis didn't yield significant and meaningful correlations between warmth vs. rejection altitude of father and thinking creatively with words. Warmth vs. rejection attitudes of father was not related to thinking creatively with pictures. However, the results from the correlational analysis yielded a number of significant and meaningful correlations between self-control vs. regulation attitudes of father and the thinking creatively with words. The self-control vs. regulation attitudes of father was significantly positively related to the thinking creatively with pictures. Third, the warmth vs. rejection attitudes of mother was significantly positively related to the thinking creatively with words. However the warmth vs. rejection attitudes of mother was not related significantly to the thinking creatively with pictures. The self-control vs. regulation attitudes of mother was not related to the thinking creatively with words. Moreover, self-control vs. regulation attitudes of mother was not related to the thinking creatively with pictures.

Structural Bioinformatics Analysis of Disease-related Mutations

  • Park, Seong-Jin;Oh, Sang-Ho;Park, Dae-Ui;Bhak, Jong
    • Genomics & Informatics
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    • 제6권3호
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    • pp.142-146
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    • 2008
  • In order to understand the protein functions that are related to disease, it is important to detect the correlation between amino acid mutations and disease. Many mutation studies about disease-related proteins have been carried out through molecular biology techniques, such as vector design, protein engineering, and protein crystallization. However, experimental protein mutation studies are time-consuming, be it in vivo or in vitro. We therefore performed a bioinformatic analysis of known disease-related mutations and their protein structure changes in order to analyze the correlation between mutation and disease. For this study, we selected 111 diseases that were related to 175 proteins from the PDB database and 710 mutations that were found in the protein structures. The mutations were acquired from the Human Gene Mutation Database (HGMD). We selected point mutations, excluding only insertions or deletions, for detecting structural changes. To detect a structural change by mutation, we analyzed not only the structural properties (distance of pocket and mutation, pocket size, surface size, and stability), but also the physico-chemical properties (weight, instability, isoelectric point (IEP), and GRAVY score) for the 710 mutations. We detected that the distance between the pocket and disease-related mutation lay within $20\;{\AA}$ (98.5%, 700 proteins). We found that there was no significant correlation between structural stability and disease-causing mutations or between hydrophobicity changes and critical mutations. For large-scale mutational analysis of disease-causing mutations, our bioinformatics approach, using 710 structural mutations, called "Structural Mutatomics," can help researchers to detect disease-specific mutations and to understand the biological functions of disease-related proteins.

Effects of Work-Related Stress on Work Ability Index among Iranian Workers

  • Gharibi, Vahid;Mokarami, Hamidreza;Taban, Abrahim;Aval, Mohsen Yazdani;Samimi, Kazem;Salesi, Mahmood
    • Safety and Health at Work
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    • 제7권1호
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    • pp.43-48
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    • 2016
  • Background: Work Ability Index (WAI) is a well-known and valid self-report tool that has been widely used in various studies to identify and avoid early retirement and work-related disability. Nevertheless, very few studies have been carried out to evaluate work ability in Iran. We aimed to investigate the WAI and the effect of work-related stress on it among Iranian workers. Methods: A cross-sectional, descriptive and analytic study was carried out among 449 workers from five working sectors in three big cities of Iran. Work ability and work-related stress were measured using the Persian version of WAI and the Persian version of Health and Safety Executive Stress Indicator Tool. Results: More than a third of the workers surveyed (34.70%) did not have an appropriate level of work ability (WAI < 37). There was a significant correlation between subscales of work-related stress and the mean score of WAI. Furthermore, the variables of body mass index, sleep quality, exercise activity, job tenure, and three subscales of work-related stress including demands, supervisor support, and role were significant predictors of WAI. Conclusion: According to the results of this study, the interventional programs must be focused on improving supervisors support, eliminating ambiguity and conflicts in the role of workers in their job and organization, reducing job demands, improving sleep quality, and increasing exercise activity.

과학체험학습에 관한 선행연구 및 경기도 지역 초등학교 운영실태 분석을 통한 다양한 과학체험학습장의 활용방안 모색 (Classification of Place for Experiential Learning through Analysis of Previous Study and Actual Status of Elementary Schools in Gyeonggi-do about Science Experience Learning)

  • 권난주;권혁재
    • 한국초등과학교육학회지:초등과학교육
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    • 제38권1호
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    • pp.43-54
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    • 2019
  • In order to organize various places for science experience study, this study gathered and analyzed prior research on science experience study and various science experience perated in school. To that end, a total of 162 relevant prior studies of literature published from 2000 to 2016 were collected and 2,201 cases of science experience study conducted in 2015 were collected and analyzed. The place where the science experiential learning was done is divided into three areas of natural ecology, cultural history, facility experiential learning study, and the characteristics of participating subjects are examined. In terms of the number of articles published in the field of science-related experiential learning areas, 83 ecological experience study sites (51.2%), facilities institution experience study sites 56 (34.6%), and cultural history experience study books 23 (14.2%). Through this study, it was found out that research tendency to analyze science - related attitudes became prominent by setting study subjects using natural objects around and learning to play while playing and playing in nature. There was also an analysis by subjects of participation in science related experience learning centers. Cultural history experiential learning field was significantly lower than previous studies. In the lower grades, nature ecological experience learning was mainly performed. Combining the above findings, it can provide implications for the development of science-related experience activities. First, it is necessary to develop a technology-related experience learning center using local community resources. Second, it is necessary to expand the culture and history experience learning center related to science. Third, we need an education support center to support the expansion and operation of such a technology-related cultural history learning center.

국내 간호사의 조직침묵 관련 요인: 체계적 문헌고찰 및 메타분석 (Factors related to the organizational silence of Korean nurses: A systematic review and meta-analysis)

  • 강경자;김정희
    • 한국간호교육학회지
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    • 제29권3호
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    • pp.302-318
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    • 2023
  • Purpose: This study aimed to identify the variables related to the organizational silence of Korean hospital nurses and to examine the effect sizes of correlations between the related variables and sub-types of organizational silence. Methods: Relevant studies were searched through a systematic search in six Korean electronic databases (RISS, ScienceON, KCI, DBpia, e-Article, and KISS) using June 2022 as the end date. Thirteen studies were identified through a systematic review and eight of them were meta-analyzed. The correlation effect size r (ESr) for each related variable was calculated. Results: Twenty-two related variables were identified from the systematic review. Of them, organizational culture was the most frequently examined. Seven variables (three organizational, two leader-member exchange, and two consequences of organizational silence) were found eligible for the meta-analysis. The intention of turnover (ESr=.39; 95% confidence interval, 95% CI=.32 to .45) and leader-member exchange ("manager's leaderships" ESr=-.33, 95% CI= -.43 to -.21; "manager's inclination to reject negative feedback" ESr=.32, 95% CI=.23 to .39) had larger correlation effect sizes than the other variables that related to organizational silence, in particular, acquiescent silence, which had the largest correlation effect size among the three sub-types of organizational silence. Conclusion: These findings show that the intention of turnover and leader-member exchanges were the main factors that related to the organizational silence. This indicates that it is necessary to develop management and education programs, as well as communication systems that focus on reducing and managing organizational silence, especially acquiescent silence.

Risk Management Qualitatively on Railway Signal System

  • Zhang, Ya-Dong;Guo, Jin
    • International Journal of Railway
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    • 제2권3호
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    • pp.113-117
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    • 2009
  • Risk management is an important part of system assurance and it is widely used in safety-related system. Railway signal system is one kind of safety-related system and its most important goal is to guarantee the safety of railway system. The method based on risk management can find and solve the security issues of railway signal system more effectively. This paper introduces the basic conception of risk management, studies the whole process of risk management and related tools and techniques and discusses some key points qualitatively combining with the particularity of railway signal system.

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국내 MIS 연구에서 구조방정식모형 활용에 관한 메타분석 (A Meta Analysis of Using Structural Equation Model on the Korean MIS Research)

  • 김종기;전진환
    • Asia pacific journal of information systems
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    • 제19권4호
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    • pp.47-75
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    • 2009
  • Recently, researches on Management Information Systems (MIS) have laid out theoretical foundation and academic paradigms by introducing diverse theories, themes, and methodologies. Especially, academic paradigms of MIS encourage a user-friendly approach by developing the technologies from the users' perspectives, which reflects the existence of strong causal relationships between information systems and user's behavior. As in other areas in social science the use of structural equation modeling (SEM) has rapidly increased in recent years especially in the MIS area. The SEM technique is important because it provides powerful ways to address key IS research problems. It also has a unique ability to simultaneously examine a series of casual relationships while analyzing multiple independent and dependent variables all at the same time. In spite of providing many benefits to the MIS researchers, there are some potential pitfalls with the analytical technique. The research objective of this study is to provide some guidelines for an appropriate use of SEM based on the assessment of current practice of using SEM in the MIS research. This study focuses on several statistical issues related to the use of SEM in the MIS research. Selected articles are assessed in three parts through the meta analysis. The first part is related to the initial specification of theoretical model of interest. The second is about data screening prior to model estimation and testing. And the last part concerns estimation and testing of theoretical models based on empirical data. This study reviewed the use of SEM in 164 empirical research articles published in four major MIS journals in Korea (APJIS, ISR, JIS and JITAM) from 1991 to 2007. APJIS, ISR, JIS and JITAM accounted for 73, 17, 58, and 16 of the total number of applications, respectively. The number of published applications has been increased over time. LISREL was the most frequently used SEM software among MIS researchers (97 studies (59.15%)), followed by AMOS (45 studies (27.44%)). In the first part, regarding issues related to the initial specification of theoretical model of interest, all of the studies have used cross-sectional data. The studies that use cross-sectional data may be able to better explain their structural model as a set of relationships. Most of SEM studies, meanwhile, have employed. confirmatory-type analysis (146 articles (89%)). For the model specification issue about model formulation, 159 (96.9%) of the studies were the full structural equation model. For only 5 researches, SEM was used for the measurement model with a set of observed variables. The average sample size for all models was 365.41, with some models retaining a sample as small as 50 and as large as 500. The second part of the issue is related to data screening prior to model estimation and testing. Data screening is important for researchers particularly in defining how they deal with missing values. Overall, discussion of data screening was reported in 118 (71.95%) of the studies while there was no study discussing evidence of multivariate normality for the models. On the third part, issues related to the estimation and testing of theoretical models on empirical data, assessing model fit is one of most important issues because it provides adequate statistical power for research models. There were multiple fit indices used in the SEM applications. The test was reported in the most of studies (146 (89%)), whereas normed-test was reported less frequently (65 studies (39.64%)). It is important that normed- of 3 or lower is required for adequate model fit. The most popular model fit indices were GFI (109 (66.46%)), AGFI (84 (51.22%)), NFI (44 (47.56%)), RMR (42 (25.61%)), CFI (59 (35.98%)), RMSEA (62 (37.80)), and NNFI (48 (29.27%)). Regarding the test of construct validity, convergent validity has been examined in 109 studies (66.46%) and discriminant validity in 98 (59.76%). 81 studies (49.39%) have reported the average variance extracted (AVE). However, there was little discussion of direct (47 (28.66%)), indirect, and total effect in the SEM models. Based on these findings, we suggest general guidelines for the use of SEM and propose some recommendations on concerning issues of latent variables models, raw data, sample size, data screening, reporting parameter estimated, model fit statistics, multivariate normality, confirmatory factor analysis, reliabilities and the decomposition of effects.

여성 결혼이민자의 심리적 안녕감이 양육효능감에 미치는 영향 (The Effects of Psychological Well-Being of Married Immigrant Women on Parenting Efficacy)

  • 이승희;박응임
    • 아동학회지
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    • 제37권2호
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    • pp.143-155
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    • 2016
  • Objective: The purpose of the study was to investigate the effects of psychological well-being on married immigrant women's parenting efficacy. Methods: The participants consisted of 145 married immigrant mothers who were members of multi-cultural family support centers in Andong, Young-ju, Uiseung, and Munkyung cities in Gyeongsangbuk-do province. Results: The main results are as follows. First, the levels of language competence and education were significantly related to psychological well-being, suggesting that the level of language competence as well as the level of education could be main factors for psychological well-being. Further, numbers of children and monthly household income were significantly related to parenting efficacy. Second, psychological well-being was correlated with parenting efficacy of married immigrant women, demonstrating that psychological well-being was the most effective variable for parenting efficacy. Third, self-acceptance, environmental mastery, and personal growth in the psychological well-being significantly predicted parenting efficacy. Conclusion: These findings suggested that we should reconsider the importance of psychological well-being in supporting programs for parenting.

한국 간호사의 미병 증상과 관련요인에 대한 국내 연구 동향 (Research Trends on Mibyeong Symptoms and Related Factors of Korean Nurses)

  • 김지영;진희정;백영화;유종향;이시우
    • 동서간호학연구지
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    • 제22권1호
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    • pp.17-23
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    • 2016
  • Purpose: The purpose of this study was to conduct a keyword analysis for exploring the symptoms of Mibyeong and related factors of Korean nurses from domestic nursing research journals from 2000 to 2015. Methods: A total of 63 studies were chosen for analysis using the keywords of "nurses", "fatigue", "pain", "sleep", "digestion", "depression", "anger", "anxiety", "stress", and "quality of life." Results: Fifteen out of 63 studies were published in the Journal of Korean Academy of Nursing Administration and studies were increasing rapidly since 2007. Keyword analysis revealed that majority of the studies were about stress, fatigue, and sleep disturbance. Symptoms of complaints in nurses were similar to those of Mibyeong in Korean Medicine. This study found that there was a need to utilize a feasible interventions in order to manage health in individuals. It is important to mange symptoms of Mibyeong in nurses since they are more vulnerable to it. Conclusion: The concept of Chi-Mibyeong may be helpful for nurses to promote their health as a prevention in Korean medicine before the onset of illness.