• Title/Summary/Keyword: Regulatory

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Growth Characteristics and Comparative Proteome Analysis of Adzuki Bean Leaves at the Early Vegetative Stage under Waterlogging Stress (논 토양 조건에서 팥 유묘기의 생육특성과 단백질 발현 양상)

  • Hae-Ryong Jeong;Soo-Jeong Kwon;Sung-Hyun Yun;Min-Young Park;Hee-Ock Boo;Hag-Hyun Kim;Moon-Soon Lee;Sun-Hee Woo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.67 no.4
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    • pp.211-221
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    • 2022
  • Recently, the demand for the cultivation of upland soil has been increasing, and the rate of conversion of paddy soil into upland soil is also increasing. Theincrease in uneven precipitation due to climate change has resulted in dramatic effects of waterlogging stress on upland crops. Therefore, the present study was conducted to investigate the changes in growth characteristics and the expression patterns of proteins at the two-leaf stage of adzuki beans. The domestic cultivar, Arari (Miryang No. 8), was used to test waterlogging stress. At the two-leaf stage of adzuki beans, plant height slightly decreased androot fresh weight showed significant changes after 3 days of waterlogging treatment. Chlorophyll content was also significantly different after 3 days of waterlogging treatment compared to its content in control plants. Using two-dimensional gel electrophoresis, more than 400 protein spots were identified. Twenty-one differentially expressed proteins from the two-leaf stage were analyzed using linear trap quadrupole-Fourier transform-ion cyclotron resonance mass spectrometry. Of these 21 proteins, 9 were up-regulated and 12 were down-regulated under waterlogging treatment. Protein information resource (https://pir.georgetown.edu/) categories were assigned to all 49 proteins according to their molecular function, cellular component localization, and biological processes. Most of the proteins were found to be involved in the biological process, carbohydrate metabolism and were localized in chloroplasts.

The Role of Tolerance to Promote the Improving the Quality of Training the Specialists in the Information Society

  • Oleksandr, Makarenko;Inna, Levenok;Valentyna, Shakhrai;Liudmyla, Koval;Tetiana, Tyulpa;Andrii, Shevchuk;Olena, Bida
    • International Journal of Computer Science & Network Security
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    • v.22 no.12
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    • pp.63-70
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    • 2022
  • The essence of the definition of "tolerance" is analyzed. Motivational, knowledge and behavioral criteria for tolerance of future teachers are highlighted. Indicators of the motivational criterion are the formation of value orientations, motivational orientation, and the development of empathy. Originality and productivity of thoughts and judgments, tact of dialogue, pedagogical ethics and tact are confirmed as indicators of the knowledge criterion. The behavioral criterion includes social activity as a life position, emotional and volitional endurance, and self-control of one's own position. The formation of tolerance is influenced by a number of factors: the social environment, the information society, existing stereotypes and ideas in society, the system of education and relationships between people, and the system of values. The main factors that contribute to the education of tolerance in future teachers are highlighted. Analyzing the structure of tolerance, it is necessary to distinguish the following functions of tolerance: - motivational (determines the composition and strength of motivation for social activity and behavior, promotes the development of life experience, because it allows the individual to accept other points of view and vision of the solution; - informational (understanding the situation, the personality of another person); - regulatory (tolerance has a close connection with the strong - willed qualities of a person: endurance, selfcontrol, self-regulation, which were formed in the process of Education); - adaptive (allows the individual to develop in the process of joint activity a positive, emotional, stable attitude to the activity itself, which the individual carries out, to the object and subject of joint relations). The implementation of pedagogical functions in the information society: educational, organizational, predictive, informational, communicative, controlling, etc. provides grounds to consider pedagogical tolerance as an integrative personal quality of a representative of any profession in the field of "person-person". The positions that should become conditions for the formation of tolerance of the future teacher in the information society are listed.

Effects of Government Business Support Projects on Corporate Growth : Focusing on the moderating effect of growth stage and use of government support (정부 기업지원 사업이 기업성장에 미치는 영향 : 성장단계 및 정부지원 활용의 조절효과를 중심으로)

  • Kim, Su gil;Hyun, Byung-Hwan
    • Journal of Technology Innovation
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    • v.31 no.2
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    • pp.333-369
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    • 2023
  • In this paper, the effect of government corporate support projects on corporate growth was analyzed, and the effect on corporate financial performance or non-financial performance was empirically analyzed by using the growth stage as a modulating variable in government support activities. As a result, it was analyzed that government corporate support had a significant effect on financial performance, non-financial performance, and use of government support, and that the moderating effect of the growth stage had a positive (+) effect on both financial and non-financial performance. Taken together, the research results showed that government corporate support had a positive effect on corporate performance, the growth stage had a positive (+) effect on both financial and non-financial performance, and the impact on financial performance was even greater. Accordingly, government support projects must be supported according to each company's growth stage, and during the decline, companies need to provide customized support according to the state of the company through industry and corporate analysis, and it is expected to be meaningful to improve the efficiency of the government's business support project.

A study of worker's stress symptoms and coping related variables: Focusing on emotional support, self-efficacy, job-satisfaction and job-performance (직장인의 스트레스 증상과 대처 관련 변인에 대한 연구: 정서적 지원, 자기효능감, 직무만족도, 직무성취도를 중심으로)

  • Young-Shin Park;Kyung-Lan Lee;Ja-Young Ahn;Sang-Hee Lee
    • Korean Journal of Culture and Social Issue
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    • v.21 no.3
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    • pp.317-338
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    • 2015
  • The main purpose of this research is to examine the relation of variables related to the worker's stress symptoms and coping. The influence of emotional support(from family, colleague, and boss), self-efficacy (self-regulatory, social, relational, resiliency, and management of work), job-satisfaction, and job-performance on worker's stress symptoms and coping is analyzed. Participants were 559 teachers (elementary 205, junior high 203, senior high 151; male 132, female 427). The results were as follows: There were no significant differences in stress symptoms and coping among primary, junior and senior high school teachers. On the other hand, there were significant differences in stress symptoms and coping between male and female teachers. Female teachers experienced more stress symptoms than male teachers. At the same time female teachers coped more efficiently in stress situation than male teachers. With emotional support, self-efficacy, job-performance and job-satisfaction as independent variables, the result of multiple regression showed that job-satisfaction has a negative influence on stress symptoms. Positive influences on stress coping was found for resiliency of self-efficacy in case of male teachers, and in case of female teachers resiliency of self-efficacy, emotional support from colleague, job-performance, and emotional support from family. Therefore, regardless of the gender of the teachers, high job-satisfaction decreased stress symptoms and high resiliency of self-efficacy increased efficient stress coping. As for female teachers, not only resiliency of self-efficacy but also emotional support from colleague and family, job-performance contributed to coping with stress.

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Acoustic outputs from clinical extracorporeal shock wave lithotripsy devices (임상에서 사용중인 체외충격파쇄석기의 음향 출력 분포)

  • Jong Min Kim;Oh Bin Kwon;Jin Sik Cho;Sung Joung Jeon;Ki Il Nam;Sung Yong Cho;Min Joo Choi
    • The Journal of the Acoustical Society of Korea
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    • v.42 no.5
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    • pp.469-490
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    • 2023
  • Survey was carried out on the acoustic outputs from 12 shock wave fields produced by the 10 extracorporeal shock wave lithotriptors whose technical documents are available, among the 33 devices approved by the Ministry of Food & Drug Safety (MFDS).The results show that the acoustic outputs (P+, P-, efd, and E), critical to the therapeutic efficacy and the patient safety, are largely different between the devices. The maximum values of P+, P-, efd, and E vary up to 2.08, 3.72, 3.89, and 15.98 times, respectively. The acoustic output parameters are not thoroughly provided in the technical documents, and some of data (eg. efd) are suspected to be abnormal outside usual ranges. The large device to device differences in the shock wave outputs are likely to undermine equivalence between the ESWL devices approved for the same indication. To verify the reliability of the data in the technical documents of the approved devices and to confirm if the acoustic outputs from the devices in clinical use are the same as those in their technical documents, an authorized test laboratory should be available. A postapproval monitoring led by the regulatory agency is suggested to maintain the acoustic outputs from the ESWL devices that suffer from degrading in performance due to aging.

Asymmetric Changes in Korean Industry and Labor after Economic Crises (경제위기 전후 산업과 노동의 불균형 변화와 미래 전략)

  • Lee, Dong Jin
    • Analyses & Alternatives
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    • v.7 no.1
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    • pp.45-81
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    • 2023
  • This paper examines how Korean economy has been asymmetrically changed after economics crises. The three crises during the last three decades, covid19, global financial crisis, and currency crisis, have deteriorated the economic inequalities of Korea in various ways. First, manufacture industry has been affected larger by economic crises, but recovered fast. The shocks in service sector were small but persist longer or were permanent. Second, although the covid19 spreaded out more to the capital area, the negative economic shock was greater in the non-capital region. That is, the crisis in the capital region transferred or amplified to the other region. Third, the inequality between permanent and temporary workers became worse after crises. Fourth, the sluggish small business growth problem became more serious during the covid19. In order to overcome the industrial and labor inequality, it is desirable to government strategy for economic development from focusing on high value-added industry to a balanced growth for all industry and region. To this end, governemt support should be asymmetric. That is, it should focus on indirect support such as regulatory reforms in the high value-added and private-led industries, and, for small business related service sector and non-capital region which have had limited opportunity of renovation and growth, the more active effort of government and government-driven gowth strategy would be desirable.

Research on Variables Related with Early Childhood Education Freshmen' Academic Interest - The Relationship Among Academic Self-Efficacy, Character Strengths and Learning Motivation - (전문대학 유아교육과 신입생의 학업흥미 관련 변인 탐색 - 학업적 자기효능감, 성격강점, 학업동기 간의 관계 -)

  • Park, Eun-Ju
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.1
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    • pp.185-197
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    • 2019
  • This study intended to analyze the early childhood education freshmen's academic interest. For this study relationship among academic self-efficacy, character strength and learning motivation. The study subjects were 144 early childhood education freshmen at K-college in Deagu. They answered the survey regarding academic self-efficacy scale, VIA-IS(Values in action inventory of strength) short form scale, school learning motivation scale. The collected data were analyzed by frequency analysis, descriptive statistics, pearson correlation and multiple regression analysis using SPSS 18.0 program. The study finding are as follows. First, the average of academic self-efficacy, character strength and learning motivation of students were near at the intermediate-level. Second, academic self-efficacy, character strength and learning motivation were significantly positive correlated. Third, when examining the relative effect of early childhood education freshmen's academic self-efficacy and character strength on learning motivation, self regulatory efficacy among the sub-factors for academic self-efficacy and courage among the sub-factors for character strengths.

Kangjeungsan(姜甑山)'s Embracement of Chinese Myth and It's Meaning (강증산(姜甑山)의 중국신화 수용과 그 의미)

  • Jung, Jae-seo
    • Journal of the Daesoon Academy of Sciences
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    • v.25_1
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    • pp.1-22
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    • 2015
  • This paper took Jeonkyeong (典經) of Daesunjinrihoe(大巡眞理會) as the basic text and studied how Kangjeungsan(姜甑山), the Sangje (上帝), had embraced Chinese myth in process of formation of his religious thought focusing on Yan Emperor(炎帝) Shennong(神農) myth and Shanrangang(禪讓) myth (namely Danchu myth). First when we examine the myth surrounding Kangjeungsan's birth, it deeply emraced a feeling-birth myth(感生神話), we could realize that this is a universe motif through myth of hero birth in East Asia. Further judging from the analysis of geographic space of Kangjeungsan's activity, it included a variety of mythical and Daoist related place names. I think this is because of the fact that birth place of Kangjeungsan and the surrounding area is the locality of Xian(仙) tradition where major characters of Danhak sect(丹學派) have been turned out, and that Korean way of Xian suppressed by the regulatory system has been widely rooted in the public. Especially it's interesting that Jeungsan, the pen name of Kangjeungsan, ambiguously connotes Siru mountain(甑山), a place of his training, and the spiritual realm of the 『Zhouyicantongqi(周易參同契)』. Then I examined the God of fire Shennong myth which has been actively admitted and embraced by Kangjeungsan. Kangjeungsan put the root of his pedigree on Shennong and there is a close affinity between Shennong and Dongyi(東夷) such as Buyeo(夫餘), Goguryeo(高句麗), etc. These Dongyi spirits are losers against the Chinese major myth and beings of ressentiment. At the same time the predecessor of Jiutianyingyuanleishengpuhuatianzun(九天應元雷聲普化天尊) who shares mythical characteristics with the God of fire Shennong was a formerly Taishi(太師) Wenzhong(聞仲) of Yin(殷) dynasty. He was defeated and died by Zhou(周) dynasty, and was deified. The fact that Kangjeungsan regarded himself as a descendent of Shennong and possessed divinity of Jiutianyingyuanleishengpuhuatianzun connotes that he represents all beings of ressentiment such as family of Yin and Dongyi. However, Kangjeungsan set a religious milestone by turning revenge for such ressentiment at tribe level into religious sublimation. At the end Shanrang myth which has been critically embraced by Kangjeungsan was reviewed. According to the existing Shanrang myth, Danchu(丹朱) was unworthy and not succeeded in the succession to the throne. Then good natured Emperor Shun(舜) succeeded to the throne from Emperor Yao(堯). However, the reality of Shanrang myth was a violent change of sovereign power and Danchu was a victim in the process of such violent change. Kangjeungsan shrewdly grasped the reality of ancient China and cast light on presence of Danchu. And he emphasized the need of religious sublimation of revenge, Haewon(解冤). His such awareness of culture had a close relation with revisionist standpoint of independent Danhak sect expressing a skeptical glance at systematic, commensurate and authentic historical view of Chinese civilization. And further Kangjeungsan cosmologically and causationally reinterpreted revenge of Danchu. He established a universal salvation theology which has a corresponsive connotation in regard to embracement of Shennong myth. In conclusion, embracement of Chinese myth by Kangjeungsan was a creative work of reinterpretation resulting in an inherent religious connotation through a process of appropriation, that is independent and selective introjection.

Infection Control in Pulmonary Function Laboratories in Domestic Hospitals (국내 의료기관의 폐기능검사실에서 감염관리 실태조사)

  • Nan-Hee LEE;Suhng Wook KIM
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.3
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    • pp.143-150
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    • 2023
  • The global outbreak of COVID-19 has underscored the pressing need for robust infection control practices in pulmonary function laboratories (PFL). However, the existing guidelines and regulatory frameworks provided by relevant authorities in the country have revealed certain deficiencies in effectively addressing this significant public health crisis. This study surveyed the infection control regulations, disposable item usage, ventilation facilities, spatial separation, and the configuration of entrance doors in 51 domestic hospital facilities from Oct 1, 2021, to Nov 2, 2021. The survey findings revealed that while there was a relatively satisfactory adherence to airborne, droplet, and contact precautions with adequate awareness and utilization of personal protective equipment, the environmental disinfection practices exhibited a suboptimal performance rate of 39.22% per patient. Depending on the specific survey domains, substantial variations were observed in the utilization of disposable items (81.05%), ventilation systems (45.75%), dedicated testing spaces (80.39%), separation of administrative areas (15.69%), and the installation of automated doors (19.61%). This study not only highlights the paramount importance of infection control in PFLs within domestic medical institutions but also provides foundational data for developing and enhancing standardized guidelines that align with international benchmarks for infection control in these settings.

IN HUMAN BREAST CANCER MCF-7 CELLS, ESTROGEN INVOLVES IN CYPIA1 GENE EXPRESSION.

  • Hwang, J.E.;S.H.Eo;Cho, S.N.;Y.Y.Sheen
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1997.04a
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    • pp.107-107
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    • 1997
  • Cytochrome P450 enzymes have been intensively investigated in hepatic tissues and several mammalian cell lines. Compared to most studies about cytochrome P450 isozymes in liver in vivo and hepatic, cell lines in vitro, the study of cytochrome P450IA1 in human breast cancer cells could be very important to understand the mechanism of the regulation of CYPIA1 gene expression and cell growth. MCF-7 human breast cancer cells are well characterized to study estrogen and antiestrogen action due to the fact that they contain high level of estrogen receptor and have biological markers characterized. And also MCF-7 cells express high level of arylhydrocarbon hydroxylase activity and human cytochrome P450IA1 cDNA was cloned from MCF-7 cells. Ah receptor was characterized in many breast cancer cell lines and polycyclic aromatic hydrocarbon such as 3-MC induced the expression of CYPIA1 gene and cytochrome P450- dependent monooxygenase activity. We undertook a study to examine the effect of estrogens and other chemicals on the regulation of human CYPIA1 gene expression in MCF-7 cells via RTPCR analysis, that might help us to understand the mechanism of the regulation of CYPIA1 gene expression and MCF-7 cell growth. Expression vector containing the functional 5'-regulatory region of human CYPIA1 fused to the CAT reporter gene was transfected into estrogen receptor positive MCF-T cells or estrogen receptor negative MDA-MB-231 cells. After these cells were treated with various chemicals, RTPCR was carried out to measure both CYPIA1 mRNA and CAT mRNA levels. 1nM 3-MC increased in both P450 and CAT mRNA levels over those of control by two folds in MCF-7 cells but does not in MDA-MB-231 cells. Estrogen or tamoxifen or retinoic acid or chrysin decreased in both P450 and CAT mRNA levels that were induced by 3-MC in MCF-7 when each chemical was administered with 3-MC concomitantly. These results suggested that the level of CYPIA1 gene expression is modulated with estrogen-related molecules and make it possible to speculate that ER is related to CYPIA1 gene expression and cell growth in breast cancer cells. [Supported by grants from the Korean Ministry of Education ]

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