• Archives of Plastic Surgery
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• 제41권6호
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• pp.620-629
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• 2014

Keloid scars are often considered aesthetically unattractive and frustrating problems that occur following injuries. They cause functional and cosmetic deformities, displeasure, itching, pain, and psychological stress and possibly affect joint movement. The combination of these factors ultimately results in a compromised quality of life and diminished functional performance. Various methods have been implemented to improve keloid scars using both surgical and non-surgical approaches. However, it has proven to be a challenge to identify a universal treatment that can deliver optimal results for all types of scars. Through a PubMed search, we explored most of the literature that is available about the intralesional injection treatment of hypertrophic scars and keloids and highlights both current (corticosteroid, 5-fluorouracil, bleomycin, interferon, cryotherapy and verapamil) and future treatments (interleukin-10 and botulinum toxin type A). The reference lists of retrieved articles were also analysed. Information was gathered about the mechanism of each injection treatment, its benefits and associated adverse reactions, and possible strategies to address adverse reactions to provide reliable guidelines for determining the optimal treatment for particular types of keloid scars. This article will benefit practitioners by outlining evidence-based treatment strategies using intralesional injections for patients with hypertrophic scars and keloids.

• 한국작물학회지
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• 제62권1호
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• pp.40-50
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• 2017

Seed storage proteins are used as carbon and nitrogen sources for the nutritional improvement of seeds. Since the composition of proteins from the Korean cultivars of proso millet is unknown, this study was conducted to obtain a reference map of millet seed proteins and identify the functional characteristics of the identified proteins. Proteins extracted from proso millet seeds of various cultivars were investigated using proteomic techniques such as 2-D electrophoresis coupled with mass fingerprinting; 1152 (differentially expressed) protein spots were detected on the 2-D gels. Among them, 26 reproducible protein spots were analyzed using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry. Out of the 26 proteins, 2 proteins were upregulated in all the millet cultivars, while 13 proteins were upregulated and 11 proteins were downregulated in 2 cultivars. Abundance of most of the identified protein species associated with polysaccharide and starch metabolism, transcription, and pathogenesis was significantly enhanced, while that of other protein species involved in glycolysis, stress response, and transduction was severely reduced. Taken together, the results suggest that the differential expression of the proteins from the four millet cultivars may be cultivar-specific. By conducting a proteomic investigation of millet seeds from different cultivars, we sought to better understand the functional categorization of individual proteins on the basis of their molecular functions. We believe that the identified proteins may help in investigating genetic variations in millet cultivars.

• 자원환경지질
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• 제31권1호
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• pp.31-43
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• 1998

A total of 469 granitic samples were collected from 44 sites in the Ulsan fault area, southeast Korea. According to the previous petrographic studies, the granitic rocks have been divided into four groups (Hornblende biotite granodiorite, Hornblende granite, Biotite granite and Alkali-feldspar granite). NRM intensities, values of low field magnetic susceptibility, and magnetic behaviors during stepwise demagnetization experiments suggest rather a three-fold classification: In this scheme, Hornblende granite and Biotite granite are grouped together, as they did not show any significant differences in magnetic characteristics. Based on the Ishihara (1979)'s criterion, Alkali-feldspar granite is classified as ilmenite-series granite, whereas others are classified as magnetite-series granite. In the eastern part of the study area including the Tertiary basin area, declinations of site-mean characteristic remanent magnetizations (ChRMs) show clockwise deflection of more than 30 from the reference direction of east Asia. Both along and in the adjacent region of the Ulsan fault-line, however, no deflection of remanent direction was observed. A boundary line between the deflected and undeflected site-mean ChRMs is defined in this study, which runs roughly parallel to the Ulsan fault-line at the distance of about 6km eastward from the fault-line. We suggest that this newly found boundary line, which we call Yonil tectonic line, released dextral simple shear stress acted in the southeastern part of the Korean peninsula during the opening stage of the East Sea in the Early Cenozoic.

• Structural Engineering and Mechanics
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• 제53권5호
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• pp.997-1016
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• 2015

The contribution of tensioned concrete between cracks (tension-stiffening) cannot be ignored when analysing deformation of reinforced concrete elements. The tension-stiffening effect is crucial when it comes to adequately estimating the load-deformation response of steel reinforced concrete and the more recently appeared fibre reinforced polymer (FRP) reinforced concrete. This paper presents a unified methodology for numerical modelling of the tension-stiffening effect in steel as well as FRP reinforced flexural members using the concept of equivalent deformation modulus and the smeared crack approach to obtain a modified stress-strain relation of the reinforcement. A closed-form solution for the equivalent secant modulus of deformation of the tensioned reinforcement is proposed for rectangular sections taking the Eurocode 2 curvature prediction technique as the reference. Using equations based on general principles of structural mechanics, the main influencing parameters are obtained. It is found that the ratio between the equivalent stiffness and the initial stiffness basically depends on the product of the modular ratio and reinforcement ratio ($n{\rho}$), the effective-to-total depth ratio (d/h), and the level of loading. The proposed methodology is adequate for numerical modelling of tension-stiffening for different FRP and steel reinforcement, under both service and ultimate conditions. Comparison of the predicted and experimental data obtained by the authors indicates that the proposed methodology is capable to adequately model the tension-stiffening effect in beams reinforced with FRP or steel bars within wide range of loading.

• Environmental Engineering Research
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• 제22권4호
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• pp.407-416
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• 2017

$CO_2$ emission is increasingly focused by public. Beijing and Tianjin are conceived to be a new economic point of growth in China. However, both of them are suffering serious environmental stress. In order to seek for the effect of socioeconomic factors on the $CO_2$ emission of this region, a novel methodology -symbolic regression- is adopted to investigate the relationship between $CO_2$ emission and influential factors of Beijing and Tianjin. Based on this method, $CO_2$ emission models of Beijing and Tianjin are built respectively. The models results manifested that Beijing and Tianjin own different $CO_2$ emission indicators. The RMSE of models in Beijing and Tianjin are 255.39 and 603.99, respectively. Further analysis on indicators and forecast trend shows that $CO_2$ emission of Beijing expresses an inverted-U shaped curve, whilst Tianjin owns a monotonically increasing trend. From analytical results, it could be argued that the diversity rooted in different development orientation and the mixture of different natural and industrial environment. This research further expands the investigation on $CO_2$ emission of Beijing and Tianjin region, and can be used for reference in the study of carbon emissions in similar regions. Based on the investigation, several policy suggestions are presented.

• 대한한의학원전학회지
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• 제19권3호
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• pp.293-304
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• 2006

The contents of ${\ulcorner}$Young Ki(營氣)${\lrcorner}$ are explained on the basis of the so-called 'Young-Yu(營衛) Circulation theory'. It was described in several chapters as ${\ulcorner}$Oh Sib Young(五十營)${\lrcorner}$ ${\ulcorner}$Yu Ki Hang(衛氣行)${\lrcorner}$ ${\ulcorner}$Young-Yu Sang Hoe(營衛生會)${\lrcorner}$. Summerizing the contents of the ${\ulcorner}$Young Ki(營氣)${\lrcorner}$ in reference to the contents of successive generation note, the contents were as follows; What attract our attention in chapter I is production process of Young Ki(營氣). Young(營) is pure nutriment which is come from food and drink. There is a close connection between Young(營) and blood. We can say that they have nearly the same meaning. The difference between the two is that Young(營) is put stress on circulation. Young Ki(營氣) is the very blood that is circulating orderly. What attract our attention in chapter II is circulation order of Young Ki(營氣). The order is described in ${\ulcorner}$Keong Mack(經脈)${\lrcorner}$ of the ${\ulcorner}$Young Chu(靈樞)${\lrcorner}$. Young Ki(營氣) is flowing according to the order of twelve Keong Mack(經脈).

• 한국산학기술학회논문지
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• 제13권7호
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• pp.3207-3215
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• 2012

본 논문에서는 3차 전단변형이론이 고려된 비국소 탄성 이론을 이용한 나노 판의 휨 및 진동에 대하여 연구하였다. 비국소 탄성 이론은 미소 규모 효과를 고려할 수 있고 3차원 전단변형이론은 나노 판의 두께방향으로의 전단 변형률과 전단응력의 곡선변화 효과를 고려할 수 있다. 이러한 두 가지 이론을 이용하여 나노 판의 처짐과 고유진동수에 미치는 비국소 이론의 효과를 제시하였다. 국소 탄성이론과의 관계를 수치해석 결과를 통하여 고찰하였다. 또한 (i) 비국소 계수, (ii) 나노 판의 적층형태, (iii) 나노 판의 보강 방향 그리고 (iv) 나노 판의 적층 수 등이 나노 판의 무차원 처짐에 미치는 효과에 대하여 관찰하였다. 본 연구의 결과를 검증하기 위해 참고문헌의 결과들과 비교 분석하였으며 해석결과는 참고문헌의 결과들과 잘 일치함을 알 수 있었다. 비국소 이론에 의한 나노 판의 처짐에 관한 연구는 향후 관련연구에 비교자료로 활용될 수 있을 것이다.

• 한국철도학회논문집
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• 제12권1호
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• pp.16-24
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• 2009

선형탄성파괴역학을 적용하여 균열이 발생한 변동하중하의 철도차량 대차틀에 대한 균열성장속도를 예측하였다. 이를 위하여 철도차량 대차틀의 균열발생사례를 분석하여 취약부위를 파악하였으며, 영업노선에서의 실동하중 측정과 구조해석을 통한 정하중 계산으로 대차틀 취약부에서 운행 중 받는 총 하중이력을 생성하였다. 총 하중이력에서 균열닫힘을 고려한 유효하중이력을 계산하였으며, 취약부 3곳에서 균열성장속도를 예측하고 일본에서 측정한 균열진전 사례와 비교하였다. 해석결과 초기길이 40mm의 균열이 급속한 균열성장을 일으키기까지는 약 50만km의 주행거리가 필요하며 이는 약 3.8년의 운행기간에 해당하므로 도시철도의 유지보수기간을 고려하면 임계균열로 도달하기 전에 충분히 감지할 수 있을 것으로 생각된다.

• 한국강구조학회 논문집
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• 제12권1호통권44호
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• pp.65-73
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• 2000

상용 유한요소해석 프로그램인 ABAQUS(ver5.8)를 이용하여 전단력을 받는 더블앵글 접합부의 3D 해석을 수행하여 접합부의 모멘트-회전 관계곡선을 구하고 앵글과 볼트의 응력분포를 관찰한다. 해석시 주요 매개변수로는 볼트수, 게이지거리, 앵글의 두께로 하였으며 유한요소해석 결과로 구한 모멘트-회전곡선을 Richard가 제시한 예측식에 적용한 후 회귀분석을 통하여 접합부 거동을 예측하는 데 필요한 매개변수인 초기강성, 소성강성, 참조모멘트, 곡선형태변수를 구한다. 또한 매개변수들이 게이지거리, 앵글의 두께 및 볼트 수 변화에 따른 그래프를 작성하고 또한 이 그래프를 이용하여 접합부의 모멘트 및 LRFD의 접합부 분류에 따른 소성모멘트에 대한 접합부 모멘트의 비를 계산한다.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.53-58
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• 2002

Electrical insulation and mechanical properties of the plasma sprayed oxide ceramic coatings were studied before and after the sealing treatment of the ceramic coatings. Plasma sprayed A1$_2$O$_3$-TiO$_2$ coating as the reference coating was sealed using three commercial sealants based on polymer. Penetration depth of the sealants to the ceramic coating was evaluated directly from the optical microscope using a fluorescent dye. It is estimated that the penetration depth of the sealants to the ceramic coating is from 0.2 to 0.5 mm depending on the sealants used. The preliminary test results with a DC puncture tester imply that the dielectric breakdown voltage mechanism of plasma sprayed ceramic coatings has been determined to be a corona mechanism. Dielectric breakdown voltage of the as-sprayed and as-ground samples have shown a linear trend with regard to the thickness showing an average dielectric strength of 20 kV/mm for the thickness scale studied. It is also shown that grinding the coating before sealing and adding fluorescent dye do not agent the penetration depth of sealants. All of the microhardness, two-body abrasive wear resistance, bond strength, and surface roughness of the ceramic coating after the sealing treatment are improved. The extent of improvement is different from the sealants used. However, three-point bending stress of the ceramic coating after the sealing treatment is decreased. This is attributed to the reduced micro-crack toughening effect since the cracks propagate easily through the lamellar of the coating without crack deflection and/or branching after the sealing treatment.