• Proceedings of the Plant Resources Society of Korea Conference
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• 2010.05a
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• pp.18-18
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• 2010

Glucosinolates(GSLs) are major secondary products($\beta$-thioglucoside N-hydroxysulfates) containing sulfates that are found mainly in Cruciferae family such as cabbage, broccoli, radish, turnip, kale, mustard and rapeseed as the important crops in agronomic and economic aspects. Especially, isothiocyanates(ITCs) have been shown to inhibit carcinogenesis with regulation cancer cell development followed by regulating target enzymes, inducing cell cycle arrest and apoptosis against various human cancer cell lines. Total desulfo(DS)-GSLs of nine type in 210 Korean leaf mustard accessions were isolated and confirmed using electrospray ionization mass spectrometric(ESI-MS/MS) method and DS-GSLs powerful library maked from several reference data. The isolated individual DS-GSLs were identified by removed $\beta$-D-glucopyranose residue ($C_6H_{11}O_5$, MW 163) from MS/MS data. Among them sinigrin(41.7%), glucoiberverin(21.7%) and gluconasturtiin(12.6%) were major components, Especially, despite gluconapin was minor component, accession K046197-1 and K046197-2 showed higher content of 4.11 and 3.31 mg/g(DW), respectively. The total GSLs contents in 210 accessions were ranged from 5.3 to 23.2 mg/g(DW) with a mean value of 13.0 mg/g(DW). As a result of principal component analysis(PCA), the individual GSLs loading plots were composed of three groups and components belonged to each group showed correlationship in quantitative pattern.

• Journal of Convergence for Information Technology
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• v.10 no.6
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• pp.177-182
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• 2020

The purpose of this study was proceed for 4weeks to determine the effect of 20's women's dysmenorrhea with self treatment programs by Jewelry bed. The subjects of this study participated 30 persons, Experimental group was performed Jewelry bed self treatment programs combined with lower body and lower extremity pattern and trunk for three times per week, during 4 weeks. A dysmenorrhea was appeared younger women's with naengkam. The results of comparison of variations in each groups showed that there was a significant difference in the experimental group(p<0.05). It looks liked limited but this research got a meaning to successful recovery motivations can gives to un-selfished peoples with dysmenorrhea problems on their physical body. Finally, It mentioned these study results will be useful as reference data for the research about the reduce for women's dysmenorrhea in the later.

• Nuclear Engineering and Technology
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• v.20 no.1
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• pp.19-26
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• 1988

The low leakage leading pattern has features as the placement of some fresh fuel assemblies in the core interior to reduce the neutron fluence on the pressure vessel and to enhance the neutron economics. But as fresh fuel assemblies are loaded in the core interior, the local power tends to exceed safety limit due to the high reactivity of the fresh assemblies. Therefore, a large number of burnable poisons must be utilized in a low leakage scheme to suppress the high assembly power as well as the excess reactivity. In this study the effects of burnable poisons are treated as a perturbation on the power distribution, and the 'Power Sensitivity Coefficient' concept is adopted. An application study is performed for cycle 1 of the Korea Nuclear Unit-7 (KNU-7) to justify the usefulness of the reverse depletion method coupled with the above concept. To obtain the optimal burnable poision distribution at the given burnup step, the linear programming technique is adopted. The result shows maximum 4.5% error in the amount of burnable poisons between the calculated and the reference values. It is concluded that the design methodology which consists of the reverse depletion, the power sensitivity coefficient concept, and the linear programming technique can be used to find the optimal turnable poison distribution.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.5 no.2
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• pp.1-8
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• 2002

The aim of this study was to generate systemic data for the aquatic plant distribution according to water depth and crossing slope in the shoreline. The results of this study were as follows; 1. Anxiety to 0 near area Bidens frondosa, Scirpus tabernaemontani, Carex dispalata etc. total class 21 observe, and Phragmites communis, Iris pseudoacorus etc. class 6 of anxiety 0-70cm extent examined. Class 21 of anxiety observed all such as Bidens frondosa, Scirpus tabernaemontani, Carex dispalata in near area to 0, and Phragmites communis, Iris pseudoacorus etc. class 6 of anxiety 0-70cm extent examined. Anxiety 70-100cm extent Nymphoides indica, Ttapa japonica etc.. class 2 appeared to line Zizania latifolia, Typha angustata back 2 papers, 130cm and examined that Nelumbo nucifera was limit anxiety state 230cm. 2. Aquatic plants of Phragmites communis, Zizania latifolia, Typha angustata etc. range mainly to gentle gradient of slant 10 degree low and distribution pattern was ranging by Zizania latifolia, Typha angustata, Phragmites communis period of ten days from deepwater place. Nelumbo nucifera was forming become independent stock keeping away invasion of plant that ability to breed was different because was prosperous. Slant 10 bores was growing near sleep in been strange steep slope earth and distribution of emerged plant appeared punily and emerged plant and swampy land plant were ranged extensively in gentle gradient of 10 degree low. 3. On lake surrounding plant when wish to do distribution of natural conditions reference need to. That is, gentle gradient and distribution form of steep slope earth are different, and same pitch must consider enough this because appear as distribution, distribution according to that some plant species were growing was different.

• Molecular & Cellular Toxicology
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• v.3 no.3
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• pp.208-213
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• 2007

With the help of a development and popularization of microarray technology that enable to us to simultaneously investigate the expression pattern of thousands of genes, the toxicogenomics experimenters can interpret the genome-scale interaction between genes exposed in toxicant or toxicant-related environment. The ultimate and primary goal of toxicogenomics identifies functional context among the group of genes that are differentially or similarly coexpressed under the specific toxic substance. On the other side, public reference databases with transcriptom, proteom, and biological pathway information are needed for the analysis of these complex omics data. However, due to the heterogeneous and independent nature of these databases, it is hard to individually analyze a large omics annotations and their pathway information. Fortunately, several web sites of the public database provide information linked to other. Nevertheless it involves not only approriate information but also unnecessary information to users. Therefore, the systematically integrated database that is suitable to a demand of experimenters is needed. For these reasons, we propose SOP (Search of Omics Pathway) database system which is constructed as the integrated biological database converting heterogeneous feature of public databases into combined feature. In addition, SOP offers user-friendly web interfaces which enable users to submit gene queries for biological interpretation of gene lists derived from omics experiments. Outputs of SOP web interface are supported as the omics annotation table and the visualized pathway maps of KEGG PATHWAY database. We believe that SOP will appear as a helpful tool to perform biological interpretation of genes or proteins traced to omics experiments, lead to new discoveries from their pathway analysis, and design new hypothesis for a next toxicogenomics experiments.

• IEMEK Journal of Embedded Systems and Applications
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• v.11 no.2
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• pp.97-105
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• 2016

Microcontrollers (MCUs) for endpoint smart sensor devices of internet-of-thing (IoT) are being implemented as system-on-chip (SoC) with on-chip instruction flash memory, in which user firmware is embedded. MCUs directly fetch binary code-based instructions through bit-line sense amplifier (S/A) integrated with on-chip flash memory. The S/A compares bit cell current with reference current to identify which data are programmed. The S/A in reading '0' (erased) cell data consumes a large sink current, which is greater than off-current for '1' (programmed) cell data. The main motivation of our approach is to reduce the number of accesses of erased cells by binary code level transformation. This paper proposes a built-in write/read path architecture using binary code inversion method based on hot-spot region detection of instruction code access to reduce sensing current in S/A. From the profiling result of instruction access patterns, hot-spot region of an original compiled binary code is conditionally inverted with the proposed bit-inversion techniques. The de-inversion hardware only consumes small logic current instead of analog sink current in S/A and it is integrated with the conventional S/A to restore original binary instructions. The proposed techniques are applied to the fully-custom designed MCU with ARM Cortex-M0$^{TM}$ using 0.18um Magnachip Flash-embedded CMOS process and the benefits in terms of power consumption reduction are evaluated for Dhrystone$^{TM}$ benchmark. The profiling environment of instruction code executions is implemented by extending commercial ARM KEIL$^{TM}$ MDK (MCU Development Kit) with our custom-designed access analyzer.

• Fashion & Textile Research Journal
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• v.19 no.4
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• pp.385-399
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• 2017

This study will broaden the application of doll costume product with historical characteristics and the image of unlined cheollik in the $17^{th}$ century period of transition during the Joseon Dynasty. Historical design sources were extracted from old documents and precedent studies. Unlined cheollik of Shin Gyeong-yu, meritorious retainer, were selected as main reference-relic because of various fabric, preserved conditions and definite shape. 'Baby doll' was selected as main model because of consumer preferences and awareness. Design sources from unlined cheollik in the early $17^{th}$ century were about a 1:2 ratio of upper and under parts, removable separated doori-somae, knife-shaped collar (outside), projected square collar (inside), long pleats line, side slit, traditional flat fell seam sewing. Trapezoidal side line, round waistline, and thin fabric were applied in designs because of toddler-body of doll model. Three designs were produced in step 1: Cheollik A focusing on the historical remake (traditional type), Cheollik B with belt and side slit (crossover type), and Cheollik C with back- opening (modern type). In step 2, interview with fashion major student was conducted to increase the utility of designs. As a result, modern trend sources (frill, velcro, round armhole line, slope of sleeves, and floral pattern) were reflected in Cheollik B, C. Finally, three doll cheollik and cheollik-styled doll apron sample were produced. Various versions must be suggested in the study of doll costume products with traditional sources that balance historical characteristics and practicality to improve customer satisfaction.

• Journal of Mechanical Science and Technology
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• v.20 no.5
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• pp.710-716
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• 2006

Micro-PIV system with a high speed CCD camera is used to measure the flow field near the advancing meniscus of a water slug in microchannels. Image shifting technique combined with meniscus detecting technique is proposed to measure the relative velocity of the liquid near the meniscus in a moving reference frame. The proposed method is applied to an advancing front of a slug in microchannels with rectangular cross section. In the case of hydrophilic channel, strong flow from the center to the side wall along the meniscus occurs, while in the case of the hydrophobic channel, the fluid flows in the opposite direction. Further, the velocity near the side wall is higher than the center region velocity, exhibiting the characteristics of a strong shear-driven flow. This phenomenon is explained to be due to the existence of small gaps between the slug and the channel wall at each capillary corner so that the gas flows through the gaps inducing high shear on the slug surface. Simulation of the shape of a static droplet inside a cubic cell obtained by using the Surface Evolver program is supportive of the existence of the gap at the rectangular capillary corners. The flow fields in the circular capillary, in which no such gap exists, are also measured. The results show that a similar flow pattern to that of the hydrophilic rectangular capillary (i.e., center-to-wall flow) is always exhibited regardless of the wettability of the channel wall, which is also indicative of the validity of the above-mentioned assertion.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3403-3406
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• 2015

Background: Skin biopsy is the method to assist clinicians to make definite dermatological diagnosis which further helps in holistic management. Skin cancers are relatively rare clinical diagnosis in developing countries like Nepal, but the prevalence is on rise. Objectives: To investigate the profile of skin biopsies and frequencies and pattern of skin cancers in a tertiary care centre of Western Nepal. Materials and Methods: The materials consisted of 434 biopsies (1.37%) out of 31,450 OPD visits performed in the Department of Dermatology, Manipal Teaching Hospital, Pokhara, Nepal, during the period of Dec 2011-Nov 2014. Data were collected and analyzed using SPSS-16 with reference to incidence, age, sex, race and clinical and histopathological features. Results: The commonest disorders observed in biopsies were papulosquamous lesions, skin tuberculosis of different types, benign skin tumors, leprosy, collagen and fungal diseases. Viral diseases were rarely seen, probably due to straight forward clinical diagnosis. Dermatological malignancies accounted for 55/434 (12.67%) of biopsies. Skin disorders in general were commoner in females 280/434 (64%), including malignancies 32/55(58.2%). Mean age of patients with skin cancer was 54.5 years. Facilities for proper laboratory investigation of dermatological disorders will improve the quality of life. Conclusions: The most prevalent lesion in skin biopsies was papulosquamous disorders followed by skin tuberculosis of different types. Dermatological malignancy constituted 55/434 (12.67%) cases. The prevalence of skin malignancy is on rise in Nepalese society probably due to increase in life expectancy and better diagnostic services.

• Nutrition Research and Practice
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• v.4 no.5
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• pp.383-392
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• 2010

This study was conducted to prepare basic materials and offer advice regarding dietary habits to prevent and cure childhood obesity by comparing and analyzing dietary habit, nutritional status, blood factors, and mineral contents of hair. All subjects were stratified by their weight-length index (WLI). According to the standard WLI values, 64.9% of children were within the normal value, 13.5% of children were underweight, and 21.6% of children were overweight and obese (WLI ${\geq}$ 110%). Overall, the score assessed dietary habit for all children was $21.32{\pm}2.55$ point (921 subjects), with 5.1% of children having excellent dietary habits and 3.1% having poor dietary habits. Additionally, 37.9% of underweight children, 37.6% of normal weight children, and 43.2% of overweight and obese children consumed higher amounts of protein than underweight children did (meat, fish, eggs, and soy products) (P < 0.05). Overweight and obese children consumed more fried foods than underweight or normal weight children (P < 0.05). Moreover, 38.0% of the children had hemoglobin levels of 12 g/dl, while 7.6% were anemic (11.1 g/dl). When a hematocrit level of 33% was taken as the standard, 11.0% of children were anemic. The plasma transferrin content was $263.76{\pm}54.52$ mg/dl in overweight and obese children. The mean values of Fe, Cu, Ca, Cr, Mn, Se, Na, K, Li, V, Co, and Mo were within the reference values, but the Zn concentrations of underweight, normal weight, and overweight and obese children were $67.97{\pm}28.51$ ppm, $70.09{\pm}30.81$ ppm, and $73.99{\pm}30.36$ ppm, respectively. The Zn concentration of overweight and obese children ($73.99{\pm}30.36$ ppm) was lower than that of the standard value (180~220 ppm). Therefore, a nutritional education program and new guidance for dietary pattern should be developed to reduce the number of underweight and overweight and obese children.