• Title/Summary/Keyword: Reduction failure

검색결과 969건 처리시간 0.021초

차전자약침(車前子藥鍼)이 Cisplatin에 의해 유발된 급성 신부전에 미치는 영향 (Beneficial Effect of Semen Plantaginis Herbal-Acupuncture on Cisplatin-Induced Acute Renal Failure in Rabbits)

  • 박춘하;채우석;윤여충
    • Journal of Acupuncture Research
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    • 제21권2호
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    • pp.155-166
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    • 2004
  • Objective : The present study was carried out to determine if Semen Plantaginis Herbal-Acupuncture exerts beneficial effect against the cisplatin-induced acute renal failure in rabbits. Method : Semen Plantaginis was selected in the basis of invigorating kidney-QI which can eliminate pathogens. The oxidative stability determined by the Rancimat technique showed higher antioxidative index when compared with control. Rabbits were treated with Semen Plantaginis Herbal-Acupuncture on Shin-shu point for 3 days, followed by cisplatin injection(5mg/kg body weight). Results : Cisplatin injection caused an increase in serum creatinine level, which was accompanied by a reduction in GFR. The fractional excretion of $Na^{+}$, $K^{+}$, glucose and phosphate increased in cisplatin-induced animals, which was partially prevented by Semen Plantaginis Herbal-Acupuncture treatment. Cisplatin injection increased lipid peroxidation, which was not prevented by Semen Plantaginis Herbal-Acupuncture. Conclusions : These results indicate that lipid peroxidation plays a critical role in cisplatin-induced acute renal failure. Semen Plantaginis Herbal-Acupuncture exerts the protective effect against acute renal failure induced by cisplatin, and its effect may be attribued to an antioxidant action.

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Critical Velocity of Fluidelastic Vibration in a Nuclear Fuel Bundle

  • Kim, Sang-Nyung;Jung, Sung-Yup
    • Journal of Mechanical Science and Technology
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    • 제14권8호
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    • pp.816-822
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    • 2000
  • In the core of the nuclear power plant of PWR, several cases of fuel failure by unknown causes have been experienced for various fuel types. From the common features of the failure pattern, failure lead time, flow conditions, and flow induced vibration characteristics in nuclear fuel bundles, it is deduced that the fretting wear failure of the fuel rod at the spacer grid position is due to the fluidelastic vibration. In the past, fluidelastic vibration was simulated by quasi -static semi-analytical model, so called the static model, which could not account for the interaction between the rods within a bundle. To overcome this defect and to provide for more flexibilities applicable to the fuel bundle, Tanaka's unsteady model was modified to accomodate the geometrical differences and governing parameter changes during the operations such as the number of rods, pitch to diameter ratio (P/D), spring force, damping coefficient, etc. The critical velocity was calculated by solving the governing equations with the MATLAB code. A comparison between the estimated critical velocity and the test result shows a good agreement. Finally, the level of decrease of the critical velocity due to the reduction in the spring force and reduced damping coefficient due to the radiation exposure is also estimated.

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팔정산(八正散) 약침(藥鍼) 및 복강(腹腔) 주입 병용 시술이 글리세롤로 유발된 토끼의 급성 신부전에 미치는 영향 (Beneficial Effect of Paljeong-san Pharmacopuncture Treatment Combined with Peritoneal Injection on Glycerol-Induced Acute Renal Failure in Rabbits)

  • 임지연;김민호;이금산;김형우;김부여;윤여충;조수인
    • 대한약침학회지
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    • 제13권3호
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    • pp.73-80
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    • 2010
  • Purpose: The present study was carried out to determine if Paljeong-san extract (PJS) treatment exerts beneficial effect against the glycerol-induced acute renal failure in rabbits. Material and Method: PJS was selected in the basis of invigorating kidney which can eliminate pathogens. Rabbits were treated with PJS pharmacopuncture on Shin-shu ($BL_{23}$) point for 5 days right after the injection of 50% concentration of glycerol ($5m{\ell}/kg$ body weight). Results and Conclusions: Glycerol injection caused an increase in serum creatinine and BUN level and urine glucose secretion, which were accompanied by a reduction in GFR. PJS Pharmacopuncture treatment combined with peritoneal injection showed beneficial effect on glycerol-induced acute renal failure by inhibition of serum creatinine increase and GFR decrease.

Wind-induced fragility assessment of urban trees with structural uncertainties

  • Peng, Yongbo;Wang, Zhiheng;Ai, Xiaoqiu
    • Wind and Structures
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    • 제26권1호
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    • pp.45-56
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    • 2018
  • Wind damage of urban trees arises to be a serious issue especially in the typhoon-prone areas. As a family of tree species widely-planted in Southeast China, the structural behaviors of Plane tree is investigated. In order to accommodate the complexities of tree morphology, a fractal theory based finite element modeling method is proposed. On-site measurement of Plane trees is performed for physical definition of structural parameters. It is revealed that modal frequencies of Plane trees distribute in a manner of grouped dense-frequencies; bending is the main mode of structural failure. In conjunction with the probability density evolution method, the fragility assessment of urban trees subjected to wind excitations is then proceeded. Numerical results indicate that small-size segments such as secondary branches feature a relatively higher failure risk in a low wind level, and a relatively lower failure risk in a high wind level owing to windward shrinks. Besides, the trunk of Plane tree is the segment most likely to be damaged than other segments in case of high winds. The failure position tends to occur at the connection between trunk and primary branches, where the logical protections and reinforcement measures can be implemented for mitigating the wind damage.

분산시스템 환경에서 조정자 선출 문제들 간의 상관관계 연구 (A Study On Relationships between Election Problems of Coordinator Under Distributed Systems)

  • Kim, Yoon
    • 한국컴퓨터정보학회논문지
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    • 제8권4호
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    • pp.35-40
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    • 2003
  • 분산시스템 환경에서, 흩어져 있는 다양한 형태의 자원들을 통제하고 관리하기 위해서는 분산된 여러 프로세스들 가운데 조정자(coordinator)로서의 역할을 담당할 특별한 프로세스를 필요로 한다. 이러한 조정자 프로세스를 통상 리더(leader)라고 부르며 리더를 선출하기 위한 알고리즘은 신뢰성있는 분산시스템을 구축하는 데 필수적인 중요한 요소가 된다. 이 논문에서는 특별히 failure detector(FD)를 구현한 비동기 분산시스템 환경에서 선출 문제 및 컨센서스 문제 간의 상관관계를 통해 제기되는 문제를 다루고자 한다. 먼저, 시스템 모델을 정의하고 그 다음으로 리더 선출을 설명한 후 마지막으로 축소 프로토콜을 이용하여 선출 문제가 컨센서스 문제에 비해 상대적으로 어려움을 증명하도록 할 것이다.

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Design of Direct-Current Fuzzy Controller for Mitigating Commutation Failure in HVDC System

  • Gao, Benfeng;Yuan, Kewei;Dong, Peiyi;Luo, Chao;Zhao, Shuqiang
    • Journal of Electrical Engineering and Technology
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    • 제13권4호
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    • pp.1450-1458
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    • 2018
  • Commutation failures can deteriorate the availability of high-voltage direct current (HVDC) links and may lead to outage of the HVDC system. Most commutation failures are caused by voltage reduction due to ac system faults on inverter side. The commutation failure process can be divided into two stages. The first stage, from the occurrence to the clearing of faults, is called 'Deterioration Stage'. The second stage, from the faults clearing to restoring the power system stability, is called 'Recovery Stage'. Based on the analysis of the commutation failure process, this paper proposes a direct-current fuzzy controller including prevention and recovery controller. The prevention controller reduces the direct current to prevent Commutation failures in the 'Deterioration Stage' according to the variation of ac voltage. The recovery controller magnifies the direct current to speed up the recovery of power system in the 'Recovery Stage', based on the recovery of direct voltage. The validity of this proposed fuzzy controller is further proved by simulation with CIGRE HVDC benchmark model in PSCAD/EMTDC. The results show the commutation failures can be mitigated by the proposed direct-current fuzzy controller.

Cyclic performance of RC beam-column joints enhanced with superelastic SMA rebars

  • Ghasemitabar, Amirhosein;Rahmdel, Javad Mokari;Shafei, Erfan
    • Computers and Concrete
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    • 제25권4호
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    • pp.293-302
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    • 2020
  • Connections play a significant role in strength of structures against earthquake-induced loads. According to the post-seismic reports, connection failure is a cause of overall failure in reinforced concrete (RC) structures. Connection failure results in a sudden increase in inter-story drift, followed by early and progressive failure across the entire structure. This article investigated the cyclic performance and behavioral improvement of shape-memory alloy-based connections (SMA-based connections). The novelty of the present work is focused on the effect of shape memory alloy bars is damage reduction, strain recoverability, and cracking distribution of the stated material in RC moment frames under seismic loads using 3D nonlinear static analyses. The present numerical study was verified using two experimental connections. Then, the performance of connections was studied using 14 models with different reinforcement details on a scale of 3:4. The response parameters under study included moment-rotation, secant stiffness, energy dissipation, strain of bar, and moment-curvature of the connection. The connections were simulated using LS-DYNA environment. The models with longitudinal SMA-based bars, as the main bars, could eliminate residual plastic rotations and thus reduce the demand for post-earthquake structural repairs. The flag-shaped stress-strain curve of SMA-based materials resulted in a very slight residual drift in such connections.

A Case Study on Engineering Failure Analysis of Link Chain

  • Kim, Tae-Gu;Lee, Seong-Beom;Lee, Hong-Chul
    • Safety and Health at Work
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    • 제1권1호
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    • pp.43-50
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    • 2010
  • Objectives: The objective of this study was to investigate the effect of chain installation condition on stress distribution that could eventually cause disastrous failure from sudden deformation and geometric rupture. Methods: Fractographic method used for the failed chain indicates that over-stress was considered as the root cause of failure. 3D modeling and finite element analysis for the chain, used in a crane hook, were performed with a three-dimensional interactive application program, CATIA, commercial finite element analysis and computational fluid dynamic software, ANSYS. Results: The results showed that the state of stress was changed depending on the initial position of the chain that was installed in the hook. Especially, the magnitude of the stress was strongly affected by the bending forces, which are 2.5 times greater (under the simulation condition currently investigated) than that from the plain tensile load. Also, it was noted that the change of load state is strongly related to the failure of parts. The chain can hold an ultimate load of about 8 tons with only the tensile load acting on it. Conclusion: The conclusions of this research clearly showed that a reduction of the loss from similar incidents can be achieved when an operator properly handles the installation of the chain.

Probabilistic analysis for face stability of tunnels in Hoek-Brown media

  • Li, T.Z.;Yang, X.L.
    • Geomechanics and Engineering
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    • 제18권6호
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    • pp.595-603
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    • 2019
  • A modified model combining Kriging and Monte Carlo method (MC) is proposed for probabilistic estimation of tunnel face stability in this paper. In the model, a novel uniform design is adopted to train the Kriging, instead of the existing active learning function. It has advantage of avoiding addition of new training points iteratively, and greatly saves the computational time in model training. The kinematic approach of limit analysis is employed to define the deterministic computational model of face failure, in which the Hoek-Brown failure criterion is introduced to account for the nonlinear behaviors of rock mass. The trained Kriging is used as a surrogate model to perform MC with dramatic reduction of calls to actual limit state function. The parameters in Hoek-Brown failure criterion are considered as random variables in the analysis. The failure probability is estimated by direct MC to test the accuracy and efficiency of the proposed probabilistic model. The influences of uncertainty level, correlation relationship and distribution type of random variables are further discussed using the proposed approach. In summary, the probabilistic model is an accurate and economical alternative to perform probabilistic stability analysis of tunnel face excavated in spatially random Hoek- Brown media.

Probabilistic stability analysis of rock slopes with cracks

  • Zhu, J.Q.;Yang, X.L.
    • Geomechanics and Engineering
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    • 제16권6호
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    • pp.655-667
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    • 2018
  • To evaluate the stability of a rock slope with one pre-exiting vertical crack, this paper performs corresponding probabilistic stability analysis. The existence of cracks is generally ignored in traditional deterministic stability analysis. However, they are widely found in either cohesive soil or rock slopes. The influence of one pre-exiting vertical crack on a rock slope is considered in this study. The safety factor, which is usually adopted to quantity the stability of slopes, is derived through the deterministic computation based on the strength reduction technique. The generalized Hoek-Brown (HB) failure criterion is adopted to characterize the failure of rock masses. Considering high nonlinearity of the limit state function as using nonlinear HB criterion, the multivariate adaptive regression splines (MARS) is used to accurately approximate the implicit limit state function of a rock slope. Then the MARS is integrated with Monte Carlo simulation to implement reliability analysis, and the influences of distribution types, level of uncertainty, and constants on the probability density functions and failure probability are discussed. It is found that distribution types of random variables have little influence on reliability results. The reliability results are affected by a combination of the uncertainty level and the constants. Finally, a reliability-based design figure is provided to evaluate the safety factor of a slope required for a target failure probability.