• 농업생명과학연구
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• 제43권6호
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• pp.7-17
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• 2009

본 연구는 소나무림을 안정적이고 지속적인 경영림으로 발달시키기 위해 우리나라 강원북부지역에 분포하는 소나무림을 대상으로 식생유형과 임분구조를 분석하였다. 소나무림의 군락유형은 3개군락 5개군 2개소군으로 총 7개 식생단위로 구분되었다. 상재도가 61%이상인 종으로는 소나무, 신갈나무, 생강나무, 큰기름새, 삽주, 진달래, 가는잎그늘사초로 나타났다. 중요치를 분석한 결과, 상층에는 소나무의 중요치가 높게 나타났으나 아교목층 이하에서는 신갈나무를 비롯한 참나무류의 중요치가 높게 나타났으며, 특히 하층에서 소나무의 치수가 거의 발견되지 않고 교목성 활엽수와 관목성 수종들의 중요치가 높게 나타났다. 또한 직경생장을 분석한 결과, 소나무에 비해 참나무류의 생장이 양호한 것으로 나타나, 강원북부지역에서 지속적인 소나무림 유지를 위해서는 각 임분의 특성을 고려하여 중 하층에서 소나무와 경쟁관계에 있는 활엽수들을 제거하는 등 적절한 시업법이 도입되어야 할 것으로 사료되었다.

• Elastomers and Composites
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• 제43권1호
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• pp.39-48
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• 2008

상용 에폭시 수지의 접착력은 XNBR을 첨가함으로써 달성할 수 있으나 이는 필연적으로 유리전이온도(Tg)의 감소를 수반하여 접착제의 내열성을 저하시킨다. 1,3-bis(3-aminopropyl) tetramethyldisiloxane과 hydroxy phthalic anhydride를 반응시켜 siloxane-imide를 합성하고, 이를 상용 에폭시 수지와 공중합시켜 변성 에폭시 수지를 합성하였다. 변성 에폭시 수지의 siloxaneimide 함량을 결정하기 위하여 접착력 및 유리전이온도를 2관능성 에폭시 수지의 경우와 비교하여 조성비를 정하였다. Siloxane-imide와 공중합된 30% 변성 에폭시 수지는 5% XNBR을 첨가한 경우 0.42 N/mm의 박리 강도와 $155^{\circ}C$의 유리전이온도를 나타내어 die-bond용 접착제에 요구되는 물성 값인 0.3 N/mm 이상의 박리 강도와 $150^{\circ}C$ 이상의 유리전이온도를 충분히 만족 시킴을 알 수 있었다. 변성 에폭시 수지의 내 산성, 내 알칼리성 및 내습성을 평가한 결과 벤젠 링과 이미드 링의 영향으로 산, 염기 조건에서는 상용 에폭시 수지 대비 무게 변화폭이 감소하였지만 수분 조건에서는 무게 변화폭이 증가한 것을 알 수 있었다. 5% XNBR을 첨가한 30% 변성 에폭시 수지의 경우, 인장응력과 신장률이 상용 에폭시 수지 대비 약 220% 향상되었는데 이는 siloxane의 유연한 성질 때문인 것으로 판단된다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제10권7호
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• pp.191-198
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• 2021

분산 딥러닝은 각 노드에서 지역적으로 업데이트한 지역 파라미터를 동기화는 과정이 요구된다. 본 연구에서는 분산 딥러닝의 효과적인 파라미터 동기화 과정을 위해, 레이어 별 특성을 고려한 allreduce 통신과 연산 오버래핑(overlapping) 기법을 제안한다. 상위 레이어의 파라미터 동기화는 하위 레이어의 다음 전파과정 이전까지 통신/계산(학습) 시간을 오버랩하여 진행할 수 있다. 또한 이미지 분류를 위한 일반적인 딥러닝 모델의 상위 레이어는 convolution 레이어, 하위 레이어는 fully-connected 레이어로 구성되어 있다. Convolution 레이어는 fully-connected 레이어 대비적은 수의 파라미터를 가지고 있고 상위에 레이어가 위치하므로 네트워크 오버랩 허용시간이 짧고, 이를 고려하여 네트워크 지연시간을 단축할 수 있는 butterfly all-reduce를 사용하는 것이 효과적이다. 반면 오버랩 허용시간이 보다 긴 경우, 네트워크 대역폭을 고려한 ring all-reduce를 사용한다. 본 논문의 제안 방법의 효과를 검증하기 위해 제안 방법을 PyTorch 플랫폼에 적용하여 이를 기반으로 실험 환경을 구성하여 배치크기에 대한 성능 평가를 진행하였다. 실험을 통해 제안 기법의 학습시간은 기존 PyTorch 방식 대비 최고 33% 단축된 모습을 확인하였다.

• 한국정보전자통신기술학회논문지
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• 제15권2호
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• pp.144-151
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• 2022

본 논문에서는 배터리 응용을 위해 저면적 DC-DC 변환기를 갖는 1.5V 256kb eFlash 메모리 IP를 설계하였다. 저면적 DC-DC 변환기 설계를 위해서 본 논문에서는 단위 전하펌프 회로에서 펌핑 노드의 전압을 VIN 전압으로 프리차징해주는 회로인 크로스-커플드 (cross-coupled) 5V NMOS 트랜지스터 대신 5V NMOS 프리차징 트랜지스터를 사용하였고, 펌핑 노드의 부스팅된 전압을 VOUT 노드로 전달해주는 트랜지스터로 5V 크로스-커플드 PMOS 트랜지스터를 사용하였다. 한편 5V NMOS 프리차징 트랜지스터의 게이트 노드는 부스트-클록 발생기 회로를 이용하여 VIN 전압과 VIN+VDD 전압으로 스윙하도록 하였다. 그리고 펌핑 커패시터의 한쪽 노드인 클록 신호를 작은 링 발진 (ring oscillation) 주기 동안 full VDD로 스윙하기 위해 각 단위 전하펌프 회로마다 로컬 인버터 (local inverter)를 추가하였다. 그리고 지우기 모드 (erase mode)와 프로그램 모드 (program mode)에서 빠져나와 대기 (stand-by) 상태가 될 때 부스팅된 전압을 VDD 전압으로 프리차징해주는 회로를 사용하는 대신 HV (High-Voltage) NMOS 트랜지스터를 사용하여 VDD 전압으로 프리차징 하였다. 이와같이 제안된 회로를 DC-DC 변환기 회로에 적용하므로 256kb eFLASH IP의 레이아웃 면적은 기존 DC-DC 변환기 회로를 사용한 경우보다 6.5% 정도 줄였다.

• ETRI Journal
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• 제26권6호
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• pp.575-582
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• 2004

Fully-depleted silicon-on-insulator (FD-SOI) devices with a 15 nm SOI layer thickness and 60 nm gate lengths for analog applications have been investigated. The Si selective epitaxial growth (SEG) process was well optimized. Both the single- raised (SR) and double-raised (DR) source/drain (S/D) processes have been studied to reduce parasitic series resistance and improve device performance. For the DR S/D process, the saturation currents of both NMOS and PMOS are improved by 8 and 18%, respectively, compared with the SR S/D process. The self-heating effect is evaluated for both body contact and body floating SOI devices. The body contact transistor shows a reduced self-heating ratio, compared with the body floating transistor. The static noise margin of an SOI device with a $1.1\;{\mu}m^2$ 6T-SRAM cell is 190 mV, and the ring oscillator speed is improved by 25 % compared with bulk devices. The DR S/D process shows a higher open loop voltage gain than the SR S/D process. A 15 nm ultra-thin body (UTB) SOI device with a DR S/D process shows the same level of noise characteristics at both the body contact and body floating transistors. Also, we observed that noise characteristics of a 15 nm UTB SOI device are comparable to those of bulk Si devices.

• Bulletin of the Korean Chemical Society
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• 제26권11호
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• pp.1728-1734
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• 2005

The interactions of Cu(II)-meso-Tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2,3,4), respectively referred to as o-, m- and p-CuTMPyP, and DNA, poly$[d(A-T)_2]$ and poly$[d(G-C)_2]$ were investigated by circular and linear dichroism (CD and LD). In the o-CuTMPyP case, in which the rotation of the pyridinium ring is prevented, the shape of the CD spectrum when associated to DNA and poly$[d(A-T)_2]$ resembles and is characterized by a positive band at a low drug to DNA concentration ratio (R ratio) and is bisignate at a high R ratio. The former CD spectrum shape has been attributed to porphyrin that is bound monomerically outside of DNA while the latter can be attributed to those that are stacked. When o-CuTMPyP is bound to poly$[d(G-C)_2]$, the excitonic CD appeared at a relatively high R ratio. In contrast, a characteristic negative CD band in the Soret region was apparent for both m- and p-CuTMPyP when bound to DNA and poly$[d(G-C)_2]$ at the low R ratios, indicating that the porphyrin molecule intercalates. However, the DNA is bent near the intercalation site and the plane of the porphyrin molecule tilts relative to the DNA helix axis, as judged by the magnitude of the reduced LD. Various stacking patterns were identified by the shape of the CD spectrum for m- and p-CuTMPyP when bound to poly$[d(A-T)_2]$. Three species for the former complex and two for the latter complex were found which may reflect the extent of the stacking.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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• pp.24-25
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• 2003

The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification of the roles of specific genes and signaling pathways in development. I will talk about positional cloning of two developmental mutants in zebrafish. The first mutant is headless: The vertebrate organizer can induce a complete body axis when transplanted to the ventral side of a host embryo by virtue of its distinct head and trunk inducing properties. Wingless/Wntantagonists secreted by the organizer have been identified as head inducers. Their ectopic expression can promote head formation, whereas ectopic activation of Wnt signalling during early gastrulation blocks head formation. These observations suggest that the ability of head inducers to inhibit Wntsignalling during formation of anterior structures is what distinguishes them from trunk inducers that permit the operation of posteriorizing Wnt signals. I describe the zebrafish headless (hdl) mutant and show that its severe head defects are due to a mutation in T-cell factor-3 (Tcf3), a member of the Tcf/Lef family. Loss of Tcf3 function in the hdl mutant reveals that hdl represses Wnt target genes. I provide genetic evidence that a component of the Wntsignalling pathway is essential in vertebrate head formation and patterning. Second mutant is mind bomb: Lateral inhibition, mediated by Notch signaling, leads to the selection of cells that are permitted to become neurons within domains defined by proneuralgene expression. Reduced lateral inhibition in zebrafish mib mutant embryos permits too many neural progenitors to differentiate as neurons. Positional cloning of mib revealed that it is a gene in the Notch pathway that encodes a RING ubiquitin ligase. Mib interacts with the intracellular domain of Delta to promote its ubiquitylation and internalization. Cell transplantation studies suggest that mib function is essential in the signaling cell for efficient activation of Notch in neighboring cells. (중략)

• Journal of Microbiology and Biotechnology
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• 제18권6호
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• pp.1101-1108
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• 2008

Geldanamycin and its analogs are important anticancer agents that inhibit the newly targeted heat-shock protein (Hsp) 90, which is a chaperone protein in eukaryotic cells. To resolve which geldanamycin biosynthetic genes are responsible for particular post-polyketide synthase (PKS) processing steps and in which order the reactions occur, we individually inactivated candidate genes in Streptomyces hygroscopicus subsp. duamyceticus JCM4427 and isolated and elucidated the structures of intermediates from each mutant. The results indicated that gel7 governs at least one of the benzoquinone ring oxidation steps. The gel16 was found to be involved in double-bond formation between C-4 and C-5 of 4,5-dihydrogeldanamycin, which confirmed our previous findings that this double bond is reduced during the post-PKS modification of the polyketide assembly. In addition, pro-geldanamycin, which does not possess a double bond at C-4/5, was purified from the gel7 and gel8 double-gene-inactivated mutant.

• Asian-Australasian Journal of Animal Sciences
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• 제30권1호
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• pp.85-93
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• 2017

Objective: This study evaluated the effect of acid whey and freeze-dried cranberries on the physicochemical characteristics, lipid oxidation and fatty acid composition of nitrite-free fermented sausage made from deer meat and pork fat. Antioxidant interactions between acid whey and cranberry compounds were also explored. Methods: Four formulations of fermented venison sausage were prepared: F1 (control), F2 (with 5% liquid acid whey), F3 (with 0.06% of freeze-dried cranberries), and F4 (with 5% liquid acid whey and 0.06% of freeze-dried cranberries). Each sample was analyzed for pH, water activity ($a_w$), heme iron content, 2-thiobarbituric acid reactive substances (TBARS) value and conjugated dienes at the end of the manufacturing process and at 30 and 90 days of refrigerated storage. Fatty acid composition was measured once at the end of the manufacturing process. Results: At the end of ripening, all samples presented statistically different values for a pH range of 4.47 to pH 4.59. The sum of the unsaturated fatty acids was higher, while the conjugated diene and the TBARS values were lower in sausages with freeze-dried cranberries as compared to the control sausage. The highest content of heme iron (21.52 mg/kg) at day 90 was found in the sausage formulation with the addition of freeze-dried cranberries, which suggests that the addition of cranberries stabilized the porphyrin ring of the heme molecule during storage and thereby reduced the release of iron. The use of liquid acid whey in combination with cranberries appears to not be justified in view of the oxidative stability of the obtained products. Conclusion: The results suggest that the application of freeze-dried cranberries can lower the intensity of oxidative changes during the storage of nitrite-free fermented sausage made

• 미생물학회지
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• 제53권3호
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• pp.193-199
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• 2017

This study was aimed to evaluate the antimicrobial activity of Penicillium purpurogenum ED76 on several clinically important microorganisms. The endophytic fungus P. purpurogenum ED76 was previously isolated from Swietenia macrophylla leaf. The antimicrobial efficacy of P. purpurogenum ED76 dichloromethane extract was determined via disc diffusion and broth microdilution assay. A kill curve study was conducted and the morphology of extract treated bacterial cells were viewed under scanning electron microscope. The dichloromethane extract showed significant inhibitory activity on 4 test bacteria and 2 test yeasts. The minimal inhibitory concentration of the extract ranged from 125 to $1,000{\mu}g/ml$, which indicates the different susceptibility levels of the test microorganisms to the fungal extract. The kill curve study has revealed a concentration-dependent inhibition for all test microorganisms. With the increase of the extract concentration, the microbial growth was significantly reduced. The scanning electron micrograph of dichloromethane extract-treated Staphylococcus aureus cells showed the total damage of the cells. The cell wall invagination of the bacterial cells also indicates the loss of cellular materials and metabolic activity. The gas chromatography mass spectrometry analysis of the extract also showed that the major compound was stigmasterol, which constitutes 45.30% of the total area. The dichloromethane extract of P. purpurogenum ED76 exhibited significant inhibitory activity on several clinically important bacteria and yeasts. The study proposed a possible mode of action that the extract cause significant damage to the morphology of S. aureus cells.