• The Korean Journal of Nuclear Medicine Technology
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• v.21 no.2
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• pp.55-64
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• 2017

Purpose Recently, with the spread of SPECT/CT, various image correction methods can be applied quickly and accurately, which enabled us to expect quantitative accuracy as well as image quality improvement. Among them, the Collimator Detector Response(CDR) recovery is a correction method aiming at resolution recovery by compensating the blurring effect generated from the distance between the detector and the object. The purpose of this study is to find out quantitative change depending on the change in detection distance in SPECT/CT images with CDR recovery applied. Materials and Methods In order to find out the error of acquisition count depending on the change of detection distance, we set the detection distance according to the obit type as X, Y axis radius 30cm for circular, X, Y axis radius 21cm, 10cm for non-circular and non-circular auto(=auto body contouring, ABC_spacing limit 1cm) and applied reconstruction methods by dividing them into Astonish(3D-OSEM with CDR recovery) and OSEM(w/o CDR recovery) to find out the difference in activity recovery depending on the use of CDR recovery. At this time, attenuation correction, scatter correction, and decay correction were applied to all images. For the quantitative evaluation, calibration scan(cylindrical phantom, $^{99m}TcO_4$ 123.3 MBq, water 9293 ml) was obtained for the purpose of calculating the calibration factor(CF). For the phantom scan, a 50 cc syringe was filled with 31 ml of water and a phantom image was obtained by setting $^{99m}TcO_4$ 123.3 MBq. We set the VOI(volume of interest) in the entire volume of the syringe in the phantom image to measure total counts for each condition and obtained the error of the measured value against true value set by setting CF to check the quantitative accuracy according to the correction. Results The calculated CF was 154.28 (Bq/ml/cps/ml) and the measured values against true values in each conditional image were analyzed to be circular 87.5%, non-circular 90.1%, ABC 91.3% and circular 93.6%, non-circular 93.6%, ABC 93.9% in OSEM and Astonish, respectively. The closer the detection distance, the higher the accuracy of OSEM, and Astonish showed almost similar values regardless of distance. The error was the largest in the OSEM circular(-13.5%) and the smallest in the Astonish ABC(-6.1%). Conclusion SPECT/CT images showed that when the distance compensation is made through the application of CDR recovery, the detection distance shows almost the same quantitative accuracy as the proximity detection even under the distant condition, and accurate correction is possible without being affected by the change in detection distance.

• Science of Emotion and Sensibility
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• v.11 no.4
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• pp.637-644
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• 2008

Human emotion has been tried to be recognized by physiological measurements in developing emotion machine enabling to understand and react to user's emotion. This study is to find the time-dependent physiological measurements and their variation characteristics for discriminating emotions according to dimensional emotion model. Ten university students were asked to watch sixteen prepared images to evoke different emotions. Their subjective emotions and autonomic nervous responses such as ECG (electrocardiogram), PPG (photoplethysmogram), GSR (Galvanic skin response), RSP (respiration), and SKT(skin temperature) were measured during experiment. And these responses were analyzed into HR(Heart Rate), Respiration Rate, GSR amplitude average, SKT amplitude average, PPG amplitude, and PTT(Pulse Transition Time). TDPs(Time dependent parameters) defined as the delay, the activation, the half recovery and the full recovery of respective physiological signal in this study have been determined and statistically compared between variations from different emotions. The significant tendencies in TDP were shown between emotions. Therefore, TDP may provide useful measurements with emotion recognition.

• Journal of Sasang Constitutional Medicine
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• v.7 no.2
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• pp.213-225
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• 1995

In order to investigate experimentally the effects of $So{\breve{u}}m$-In Bojungikit'ang and Dong-Won Bojungikit'ang on Yang-Insufficient syndrome(陽虛證) induced by Hydrocortisone acetate(HA) in experimental animals(Mice and Rats), the author experimented with various activities. Body temperature(BT), Body weight(BW), Exercise time, Cyclic-AMP, the Ra's Hair condition was measured. The results obtained are as follows : 1. In body temperature, the Dong-Won Bojungiki'ang treated group was increased significantly and the $So{\breve{u}}m$-In Bojungikit'ang treated group showed no significance. 2. In body weight, the $So{\breve{u}}m$-In Bojungikit'ang treated group had increased significantly and the Dong-Won Bojungikit'ang treated group showed no significance and there was a significant difference between the $So{\breve{u}}m$-In Bojungikit'ang and the Dong-Won Bojungikit'ang. 3. In exercise time. the $So{\breve{u}}m$-In Bojungikit'ang and the Dong-Won Bojungikit'ang treated groups were significantly increased. 4. In cyclic AMP, both experimental groups showed increasing tendancy, but showed no significance. 5. In the Rat' s hair condition. the $So{\breve{u}}m$-In Bojungikit'ang showed significance. 6. There was no significant difference between the $So{\breve{u}}m$-In Bojungikit'ang and the Dong-Won Bojungikitang except the body weight. from the above findings. (1) it has been demonstrated thet the $So{\breve{u}}m$-In Bojungikit'ang and Dong-Won Bojungikit'ang groups seem to produce the effecticeness on the recovery from depression of metabolism induced by Bydrocortisone acetate. (2) In body temperature response the Dong-Won Bojungikit'ang had effectiveness during recovery. (3) In body weight response the $So{\breve{u}}m$-In Bojungikit'ang had the effecticeness during recovery. (4) In exercise time. Both experimental group had the effectiveness during recovery. (5) In cyclic AMP response. both experimental group had no effectiveness during recovery. (6) In the Rat's hair condition response the $So{\breve{u}}m$-In Bojungikit'ang group had the effectiveness during recovery. Therefore in is suggested theat the $So{\breve{u}}m$-In Bojungikit'ang and Dong-Won Bojungikit'ang groups had effecticeness during recovery from Yang-Insufficient syndrome more of less.

• Journal of Information Processing Systems
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• v.15 no.1
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• pp.55-66
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• 2019

Storage system often applies erasure codes to protect against disk failure and ensure system reliability and availability. Liberation code that is a type of coding scheme has been widely used in many storage systems because its encoding and modifying operations are efficient. However, it cannot effectively achieve fast recovery from single disk failure in storage systems, and has great influence on recovery performance as well as response time of client requests. To solve this problem, in this paper, we present HRSF, a Hybrid Recovery method for solving Single disk Failure. We present the optimal algorithm to accelerate failure recovery process. Theoretical analysis proves that our scheme consumes approximately 25% less amount of data read than the conventional method. In the evaluation, we perform extensive experiments by setting different number of disks and chunk sizes. The results show that HRSF outperforms conventional method in terms of the amount of data read and failure recovery time.

• The Korean Journal of Physiology and Pharmacology
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• v.2 no.3
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• pp.345-351
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• 1998

The role of nitric oxide (NO) in the hemorrhagic hypotension was examined using a NO synthase inhibitor, $N^{\omega}-nitro-L-arginine$ methyl ester (L-NAME), in conscious rats. The rats were bled at a constant rate (2 ml/kg/min) through a femoral arterial catheter until the mean arterial pressure (MAP) was reduced by 50 mmHg. We studied the responses to hemorrhage under normal condition (Control) and after the pretreatment with 3 doses of L-NAME (1.6, 8, 40 mg/kg i.v. of NOX1.6, NOX8, and NOX40, respectively). Intravenous bolus injection of L-NAME produced a sustained increase in MAP and decrease in heart rate (HR). During hemorrhage, the MAP fell faster in the NOX8 and NOX40-treated groups than in Control group, but the control group showed same response to NOX1.6. HR greatly increased in NOX groups. The recovery from hemorrhagic hypotension was slowed in the control group, which was not treated with L-NAME. In comparison with the control group, NOX8 and NOX1.6-treated groups registered a significant recovery in MAP during the 15 min recovery period, but NOX40 brought about only a slight increase in MAP. NO precursor, L-arginine (150 mg/kg i.v.), produced significant bradycardic responses before and after hemorrhage and significant depressor response only after hemorrhagic hypotension regardless of pretreatment with L-NAME. These data suggest that the role of NO in blood pressure regulation is greater after hemorrhagic hypotension than basal condition, but the effect of NO can be detrimental to the recovery from hemorrhagic hypotension. In addition, the bradycardic response of L-arginine provides indirect evidence that NO may inhibit sympathetic activity, especially after hemorrhagic hypotension.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.20 no.10
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• pp.900-906
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• 2010

This note proposes vibration-free motor control through modified LQG/LTR methodology. A conventional LQG/LTR method is a design tool in the frequency domain. However, unlike the conventional one, the proposed one is a time response based design method. This feature is firstly designed by parameterized settling time control gain through the target loop design procedure and the feature is secondly realized by loop transfer recovery. In order to show convergence to the target loop transfer functions, asymptotic behaviors of the open and the closed loop transfer functions are shown. At the conclusion, it is verified that the proposed method is robustly stable to parametric uncertainties through ${\mu}$-plot.

• Korean Journal of Pharmacognosy
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• v.18 no.4
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• pp.216-232
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• 1987

In order to investigate the preventive and therapeutic effects of Herba Houttuyniae, experimental studies on the immune response and histological findings were undertaken. The results of these studies were summarized as follows; Delayed type hypersensitivity and rosette formation rate were significantly increased compared with control group. Hemagglutination, hemolysin titer and NK cell activity were variable, not significantly against the control group. When observed on lung tissue recovery; experimental groups were shown to be significantly recovered as compared with the control group. From these results, it is suggested that Houttuyniae Herba promotes immune response and reduces the recovery time of pneumonitis and lung abscess from the histological viewpoint.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.7
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• pp.994-1001
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• 2000

The dynamic behavior of a single-pressure heat recovery steam generator and turbine system for the combined cycle power plant is simulated on the basis of one-dimensional unsteady governing equations. A water level control and a turbine power control are also included in the calculation routine. Transient response of the system to the variation of gas turbine exit condition is simulated and effect of the turbine power control on the system response is examined. In addition, the effect of the treatment of inertia terms(fluid inertia and thermal inertia of heat exchanger metal) on the simulated transient response is investigated.

• Journal of Korean Academy of Nursing
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• v.36 no.4
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• pp.621-629
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• 2006

Purpose. The purpose of this study was to identify the clinical variables that predict functional and cognitive recovery at 1- and 6-month in both severe and moderate/mild traumatic brain injury patients. Methods. The subjects of this study were 82 traumatically brain-injured patients who were admitted to a Neurological Intensive Care Unit at a university hospital. Potential prognostic factors included were age, motor and pupillary response, systolic blood pressure, heart rate, and the presence of intracranial hematoma at admission. Results. The significant predictors of functional disability in severe traumatic brain injury subjects were, age, systolic blood pressure, the presence of intracranial hematoma, motor response, and heart rate at admission. In moderate/mild traumatic brain injury patients, motor response, abnormal pupil reflex, and heart rate at admission were identified as significant predictors of functional disability. On the other hand, the significant predictors of cognitive ability for severe traumatic brain injury patients were motor response and the presence of intracranial hematoma at admission, whereas those for moderate/mild patients were motor response, pupil reflex, systolic blood pressure at admission, and age. Conclusions. The results of the present study indicate that the significant predictors of TBI differ according to TBI severity on admission, outcome type, and outcome measurement time. This can be meaningful to critical care nurses for a better understanding on the prediction of brain injury patients. On the other hand, the model used in the present study appeared to produce relatively low explicabilities for functional and cognitive recovery although a direct comparison of our results with those of others is difficult due to differences in outcome definition and validation methods. This implies that other clinical variables should be added to the model used in the present study to increase its predicting power for determining functional and cognitive outcomes.

• Molecular & Cellular Toxicology
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• v.4 no.4
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• pp.331-337
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• 2008

This study was conducted to quantitatively evaluate the recovery effects of herbal medicines on acetaminophen-induced hepatotoxicity. In the present study, the recovery effects of 251 herbal medicines on THLE-2 cells that had been damaged by acetaminophen were evaluated using an MTS assay. THLE-2 cells were cultured in 96-well plates and then pretreated with or without 60 ${\mu}M$ acetaminophen (${IC}_{50}$ value: 35.84) for 1 hr. Next, different herbal medicines were added to the wells, after which the cells were reincubated at $37^{\circ}C$ for 24 hr. After first round of screening, the candidate herbal medicines were selected based on a recovery rate of greater than 40% and their efficacy were then determined by dose response kinetic analysis. Among these extracts, 8 herbal medicines (Terminalia chebula, Pueraria lobata, Acronychia laurifolia, Lopatherum gracile, Oroxylum indicum, Cynanchum atratum, Senecio scandens, and Sophora flavescens) had a strong recovery effect on acetaminophen-induced damage in THLE-2 cells. Dose response non-linear regression analysis demonstrated that Senecio scandens showed the best recovery rate (98%), and that its ${EC}_{50}$ was 19.54 ng/mL. Additional studies of these herbal medicines should be conducted to determine if they possess novel therapeutic agents for the prevention or treatment of liver disorders.