• Journal of the korean academy of Pediatric Dentistry
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• v.37 no.2
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• pp.207-212
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• 2010

Protein C deficiency increases the risk of thrombosis due to the lack of anticoagulant factor protein C. Among the numerous congenital protein C deficiencies, homozygous protein C deficiency has an especially low protein C activity level, that it is almost undetectable. It is a rare disease with a probability of 1:250000~500000. The signs and symptoms of homozygous protein C deficiency include purpuric, necrotic dermatosis, ecchymosis, blindness, and thrombosis in central nervous system. A 4-year-old girl was brought to the clinic with a chief complaint of extensive caries. The child was under warfarin medication in order to prevent possible complications during dental treatment. We consulted the pediatric department. Without warfarin intake, serious complications may occur due to thrombosis during dental treatment. Therefore, certain warfarin dosage (INR 3~5) and fresh frozen plasma as a backup for excessive hemorrhage were recommended. This child was a severely disabled child with the loss of vision, and it was difficult to manage her behavior effectively. Thus, dental treatment was carried out under general anesthesia, where bleeding control would be also easier to achieve.This report presents the case of a 4-year-old girl with protein C deficiency, who has received dental treatment for extensive caries under general anesthesia.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3593-3599
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• 2014

Background: Efficacy of childhood cancer treatment in low-income countries may be impacted by parents' and health-care providers' perspectives on chemotherapy-related side-effects. This study explores prevalence and severity of side-effects in childhood cancer, and compares health beliefs about side-effects between parents and health-care providers, and between nurses and doctors in Indonesia. Materials and Methods: Semi-structured questionnaires were filled in by 40 parents and 207 health-care providers in an academic hospital. Results: Parents exporessed a desire to receive more information about side-effects (98%) and worried about this aspect of treatment (90%), although side-effects were less severe than expected (66%). The most frequent was behavior alteration (98%) and the most severe was hair loss. Only 26% of parents consulted doctors about side-effects. More parents, compared to health-care providers, believed that medicines work better when side-effects are more severe (p<0.001), and accepted severe side-effects (p=0.021). More health-care providers, compared to parents, believed that chemotherapy can be stopped or the dosage altered when there are side-effects (p=0.011). More nurses, compared to doctors, stated that side-effects were unbearable (p=0.004) and made them doubt efficacy of treatment (p<0.001). Conclusions: Behavior alteration is the most frequent and hair loss the most severe side-effect. Apparent discrepancies in health beliefs about side-effects exist between parents and health-care providers. A sustainable parental education program about side-effects is recommended. Health-care providers need to update and improve their knowledge and communication skills in order to give appropriate information. Suchmeasures may improve outcome of childhood cancer treatment in low-income countries, where adherence to therapy is a major issue.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.50 no.spc1
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• pp.99-103
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• 2005

Nitrogen content of liquid manures varies from $3g\;kg^{-1}\;to\;7g\;kg^{-1}$ according to the collecting seasons. The application effects of liquid manure on the yield of rice are the best in LPM+LPM treatment, although the lodging of crops increased and the quality of rice is deteriorated. When application with LPM+CF treatment and CF+LPM treatment showed no difference in rice yield and quality, compared with CE+CF treatment. Therefore, use of liquid manure on farmland should be limited as once per year during cultivation duration and liquid manure is fully fermented during 6 months at least in order to decrease the damage of crops by application of unmatured liquid manure. Also, application amount of liquid manure should be carefully determined by considering the mineral (especially nitrogen) contents of liquid manure and the recommended fertilizer levels for various crops.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.650-657
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• 2011

The object of this study was to obtain acute information (single oral dose toxicity) of Taraxaci Herba (Dried total parts of Taraxacum platycarpum. H.Dahlstedt (Compositae)), has been traditionally used in Korean medicine for treating various inflammatory diseases. In order to observe the 50% lethal dose (LD 50), approximate lethal dosage (ALD) and target organs, test articles were once orally administered to female and male ICR mice at dose levels of 2,000, 1,000, 500 mg/kg according to the recommendation of Korea Food and Drug Administration Guidelines. The mortality and changes on body weight, clinical signs and gross observation were monitored during 14 days after single oral treatment of Taraxaci Herba aqueous extracts according to KFDA Guidelines with organ weights and histopathological observations of 12 types of principle organs. After single oral treatment of Taraxaci Herba aqueous extracts, we could not find any mortality and toxicological evidences up to 2,000 mg/kg treated group, the limited dosages in rodents at body and organ weights, clinical signs, gross and histopathological observations. Except for slight soft feces, which were detected in male mice treated with 2,000 mg/kg of Taraxaci Herba aqueous extracts at 1 day after end of treatment. The results obtained in this study suggest that the LD 50 and ALD of Taraxaci Herba aqueous extracts in both female and male mice after single oral treatment were considered as over 2,000 mg/kg because no mortalities were detected up to 2000 mg/kg that was the highest dose recommended by KFDA and OECD. However, it also observed that the possibility of digestive disorders, like diarrhea when administered over 2,000 mg/kg of Taraxaci Herba aqueous extracts in the present study, but these possibilities of digestive disorders can be disregard in clinical use because they ate transient in the highest dosages male only.

• Korean Journal of Ecology and Environment
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• v.39 no.4 s.118
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• pp.471-480
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• 2006

The field scale experiment was performed to examine the performance of the constructed wetland for nonpoint source (NPS) pollution loading reduction. Four sets (each set of 0.88 ha) of wetland (0.8 ha) and pond (0.08 ha) systems were used. Water flowing into the Seokmoon estuarine reservoir from the Dangjin stream was pumped into wetland systems. Water depth was maintained at 0.3-0.5 m and hydraulic retention time was managed to about 2-5 days; emergent plants were allowed to grow in the wetland. The wetland effluent concentrations of $BOD_5$, TSS, and T-N were higher in winter than in the growing season excepting the T-P, and effluent $BOD_5$ concentration was higher than influents in winter. Mass retention of T-N and T-P was stable throughout the year, whereas mass retention of $BOD_5$ and TSS was decreased in winter. $BOD_5$, TSS, T-N, and T-P performance of the experi-mental system was compared with the existing database (North American Treatment Wetland Database), and was within the range of general system performance. From the first-order analysis, T-P was virtually not temperature dependent, and $BOD_5$ and TSS were more temperature dependent than T-N. Overall, the wetland system was found to be an adequate alternative for treating polluted stream water with stable removal efficiency and recommended as a NPS control measures.

• Journal of Korean Academy of Nursing Administration
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• v.3 no.2
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• pp.123-136
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• 1997

The purpose of this study was to confirm the classification of nursing activity and to analyze the time of nursing workload in a new open hospital. The data were collected from 20 nurses working in 6 general nursing units by 4 trained observers. The tools used for this study were an observation recording sheet and a classification sheet of nursing activity. The classification sheet was constructed to be adaptable to each hospital system based on the instrument described in the literature. The results of the study are as follows : The direct nursing activities consisted of 6 sections, 33 subsections and the indirect nursing activities consisted of 14 sections, 53 subsections. The direct nursing activities included medication, measuring and observation, care of therapies, care of physical comfort, laboratory and treatment. The indirect nursing activities included preparation of medical utensils, collection of information and assessment, recording, phone communication, professional interaction related to patients, personal time, assigning work to staff, patient eaucation and training, interaction with lab, transfer of administration of utensils, checking physician's order, dietary service, management of pollution and contagion, guide direction. Nurses spent 127.6min for direct nursing activity during day duty. It was 24.5% of total nursing activity. Within that activity medication had the highest percentage of time(40.09%), followed by communication and education with patient(24.76%), measuring and observation (16.93%), laboratory and treatment (12.85%), care of therapies(3.21%) and care of physical comfort (2.16%). The time breakdown for indirect nursing activities is as follows ; the preparation of medical utensils 22.3%, collection of information and assessment 20.29%, recording 20.27%, phone communication 8.14%, professional interaction related to patients 7.33%, personal time 7.24%, with the remaining timeshared by staffing, patient education and training, interaction with lab, transfer of administration of utensils, checking physician's order, dietary service, management of pollution and contagion, guide direction. In the analysis of the relationships between the working time and the work allocation characters of the nurses(including nurse's experiences. nurse-patients ratio, nurse-rooms ratio, and character of nursing unit) ; There were no significant differences in direct-indirect nursing times between nurse's career years. There was significant difference in direct nursing time between assigned patient numbers. The nurses assigned larger number of patients spent significantly more time in direct nursing care than that of the smaller. On the other hand, there was no significant difference in indirect nursing workload between the assigned patient numbers. There were no significant differences in direct-indirect nursing time between an allocated patient's room numbers. There was significant difference in working time between working places. The nurse in the medical unit spent more time in direct nursing care than her counterpart in the surgical unit. However there was no difference in direct nursing time between two groups. The study results indicate that nurses spent less time in the direct nursing care than in the previous studies even though the hospital system has been modernized. On the other hand they spent much more time for the coordinating role within the interdisciplinary team and for the overlapping paperwork. Therefore it is recommended that patient oriented job description and more efficient usage of modernized utilities be made.

• Korean Journal of Soil Science and Fertilizer
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• v.44 no.3
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• pp.425-433
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• 2011

In order to obtain optimum pre-treatment methods and improve T-N and T-P removal efficiencies, removal rates of pollutants in small-scale livestock wastewater treatment apparatus with water plant filtration bed or activated sludge tank were investigated. Based on the results from the optimum pre-treatment in small-scale livestock wastewater treatment apparatus, removal efficiencies of pollutants in livestock wastewater treatment plant with water plant filtration and activated sludge beds. The removal rates of COD, SS, T-N, and T-P in effluent were 83, 89, 63 and 87% in small-scale livestock wastewater treatment apparatus with water plant filtration bed, respectively. The removal rates of COD, SS, T-N, and T-P in effluent were 96, 95, 86 and 92% in small-scale livestock wastewater treatment apparatus with activated sludge tank, respectively. For increasing the COD, SS, T-N, and T-P removals in small-scale livestock wastewater treatment apparatus, the water plant filtration and activated sludge beds are recommended. In livestock wastewater treatment plant with water plant filtration ($1^{st}$ treatment) and activated sludge ($2^{nd}$ treatment) beds, the concentrations of COD, SS, T-N, and T-P in effluent were 39, 15, 42 and $1mg\;L^{-1}$, respectively. It was shown that the concentrations of COD, SS, T-N, and T-P met acceptable effluent quality standard for livestock wastewater. Based on the above results, the removal rates of COD, SS, T-N, and T-P in effluent were over 99.8, 99.9, 99.2, and 99.9% in livestock wastewater treatment plant, respectively.

• Korean Journal of Animal Reproduction
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• v.5 no.1
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• pp.36-42
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• 1981

This experiment was carried out to determine the optimum interval between inseminations in artifical insemination of hens. Two hundred and forty hens of Hisex commercial stock at 25 weeks of age and 20 cocks of the Rhode Island Red at 40 weeks of age were used for the experiment, and a total of 6,784 eggs were obtained. The intervals between inseminations compared in this study were: 3 days (T1), 5 days (T2), and 7 days(T3). Mixed raw semen was inseminated and the semen does was 0.03ml per insemination per hen. The inseminations were conducted at 15:00 at each time. The total number of insemination performed was 9 for the T1, 6 for the T2 and 5 for the T3, and eggs were collected over a period of 31 days, 32 days and 35 dyas, respectively. The average egg production of the hens during the experiment was 85.9% and the average temperature during the experiment was around 30$^{\circ}C$. The average sperm count was 3.69 billion per ml. The results obtained in this experiment can be summarized as follows: The fertility over the entire experimental period bythe treatment was 91.7% for the T1, 84.4% for the T2, and 75.2% for the T3. The difference between T1 and T3 in fertility was significant at 5% level. The average fertility on the second, third and fourth day after the insemination in the T2 and T3 was maintained at a relatively high level, but it tended to decline rapidly from the fifth day after the insemination. The average fertility for one week after the last insemination was 88.8% for the T1, 88.8% for the T2 and 78.6% for the T3, and none of the differences among the treatments were statistically significant. On the basis of the results from this study, it is recommended to adjust the insemination intervals within the range from the 3 to 5 days in order to maintain a highest level of fertility in the hens at an early stage of egg production as in the case of the hens used in this experiment. An insemination interval of 3 days is recommended, especially at an initial stage of insemination. For the hens with a low fertility, shortening, of the insemination interval to 3 or 2 days is desirable.

• The Korean Journal of Pesticide Science
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• v.2 no.2
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• pp.119-125
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• 1998

A nation-wide fact-finding survey was done to provide the basic information for establishing the rational weed control scheme in paddy rice. A total of 445 respondents including 273 farmers and 172 pesticide dealers was involved in this survey. Dominant weeds in rice paddy field were Echinochloa crus-galli, Eleocharis kuroguwai, Sagittaria pygmaea, Sagittaria trifolia, etc.. Preferred herbicides widely used by farmners were ranked in the following order; butachlor 5GR, pyrazosulfuron-ethyl + molinate 5.07GR, molinate + cinosulfuron 5.08GR, meanwhile, those recommended by pesticide dealers were; pyrazosulfuron-ethyl + molinate 5.07GR, molinate + cinosulfuron 5.08GR, and butachlor 5GR. The guidelines to choose the preferred herbicides was primarily based on the experience, which was occupied about 45%. Approximately 56% of the farmers followed the recommended herbicide dosage and 43% of them applied the herbicides before weed germination (pre-emergence treatment). In addition, most farmers applied herbicides at least two times with systematic application schedule. Application method of granular formulation was broadcasting by hand, while that of sprayable ones was by high-pressure sprayer. Some farmers answered that they had experienced phytotoxicity in the crop by applied herbicides, of which higher experience was observed from the farmers who applied by high-pressure sprayer. It was analyzed significantly that the feasible herbicides to cause phytotoxicity in rice at farmer's level were butachlor 5GR, esprocarb + pyrazosulfuron-ethyl 5.07GR and bensulfuron-methyl + molinate 5.17 GR.

• Korean Journal of Soil Science and Fertilizer
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• v.43 no.4
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• pp.506-513
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• 2010

Plant growth promoting ability of Methylobacterium oryzae CBMB20 was evaluated under different levels of organic fertilizer application on red pepper plants in a pot experiment. Oil cake as an organic N fertilizer was applied at the rates of 70, 85, 100 and 120% of the conventional recommended level. Each treatment was further treated with or without M. oryzae CBMB20 inoculation. The recommended amount of compost for red pepper was added in all the treatments. Results revealed that plant height, dry biomass and fruit yield were enhanced in increasing order as the rate of fertilization increased. Overall plant growth was improved due to the inoculation of M. oryzae CBMB20 and red pepper fruit yield was also increased by 10-35% in the plants inoculated with M. oryzae CBMB20 at different rates of organic fert1izer application. Total methylotrophic bacterial population in rhizosphere soil measured at the time of harvest was significantly higher in M. oryzae CBMB20 inoculated treatments. The growth promoting effect of M. oryzae CBMB20 found in red pepper could be due to the effective colonization of the bacteria in the rhizosphere and its ability of enhancing nutrient availability and producing plant growth hormones. With the plant growth promoting effect of M. oryzae CBMB20, the rate of organic fertilizer application can be reduced without any significant decreases in biomass production and yield of red pepper.