• The Korean Journal of Nuclear Medicine Technology
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• v.23 no.1
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• pp.35-39
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• 2019

Purpose Hepatitis B virus (hepatitis B virus, HBV) infection is a worldwide major public health problem and it is known as a major cause of chronic hepatitis, liver cirrhosis and liver cancer. And serologic tests of hepatitis B virus is essential for diagnosing and treating these diseases. In addition, with the development of molecular diagnostics, the detection of HBV DNA in serum diagnoses HBV infection and is recognized as an important indicator for the antiviral agent treatment response assessment. We performed HBeAg assay using Immunoradiometric assay (IRMA) and Chemiluminescent Microparticle Immunoassay (CMIA) in hepatitis B patients treated with antiviral agents. The detection rate of HBV DNA in serum was measured and compared by RT-PCR (Real Time - Polymerase Chain Reaction) method Materials and Methods HBeAg serum examination and HBV DNA quantification test were conducted on 270 hepatitis B patients undergoing anti-virus treatment after diagnosis of hepatitis B virus infection. Two serologic tests (IRMA, CMIA) with different detection principles were applied for the HBeAg serum test. Serum HBV DNA was quantitatively measured by real-time polymerase chain reaction (RT-PCR) using the Abbott m2000 System. Results The detection rate of HBeAg was 24.1% (65/270) for IRMA and 82.2% (222/270) for CMIA. Detection rate of serum HBV DNA by real-time RT-PCR is 29.3% (79/270). The measured amount of serum HBV DNA concentration is $4.8{\times}10^7{\pm}1.9{\times}10^8IU/mL$($mean{\pm}SD$). The minimum value is 16IU/mL, the maximum value is $1.0{\times}10^9IU/mL$, and the reference value for quantitative detection limit is 15IU/mL. The detection rates and concentrations of HBV DNA by group according to the results of HBeAg serological (IRMA, CMIA)tests were as follows. 1) Group I (IRMA negative, CMIA positive, N = 169), HBV DNA detection rate of 17.7% (30/169), $6.8{\times}10^5{\pm}1.9{\times}10^6IU/mL$ 2) Group II (IRMA positive, CMIA positive, N = 53), HBV DNA detection rate 62.3% (33/53), $1.1{\times}10^8{\pm}2.8{\times}10^8IU/mL$ 3) Group III (IRMA negative, CMIA negative, N = 36), HBV DNA detection rate 36.1% (13/36), $3.0{\times}10^5{\pm}1.1{\times}10^6IU/mL$ 4) Group IV(IRMA positive, CMIA negative, N = 12), HBV DNA detection rate 25% (3/12), $1.3{\times}10^3{\pm}1.1{\times}10^3IU/mL$ Conclusion HBeAg detection rate according to the serological test showed a large difference. This difference is considered for a number of reasons such as characteristics of the Ab used for assay kit and epitope, HBV of genotype. Detection rate and the concentration of the group-specific HBV DNA classified serologic results confirmed the high detection rate and the concentration in Group II (IRMA-positive, CMIA positive, N = 53).

• Archives of design research
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• v.17 no.2
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• pp.199-208
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• 2004

In cyberspace based on internet, users constitute communities and interact one another. Avatar means not only the other self but also the 'another being' that describes oneself in the cyberspace. If user's avatar shows expressive faces and behaves according to his thinking and emotion, he will have a feel of reality much more in the cyberspace. If avatar's countenances can be animated by just typing characters in avatar-based chat communication, the user is able to express his emotions more effectively. In this study, emotion-expressing vocabulary is analyzed and classified. Emotion-expressing vocabulary is essential to develop self-reactive avatar system in which avatar's countenances are automatically converted according to the words typed by users at chat. The results are as follows; First, emotion-expressing vocabulary selected out of Korean adjectives and intransitive verbs is made up of 209 words and is classified into 25 groups. Second, there are only 2 groups out of the 25 groups for positive expressions and others are for negative expressions. Therefore, negative expressions are more abundant than positive expressions in Korean vocabulary. Third, avatar's countenances are modelled according to the 25 groups by using the Quantification Method 3. The result shows that the emotion-expressing vocabulary has dose relations with avatar's countenances and is useful to communicate users' emotions. However, this study has some limits, in that Korean linguistical structure - the whole meaning of context - cannot be interpreted quantitatively.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.6
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• pp.527-534
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• 2017

The purpose of this study is to develop unmanned equipment that can automatically move to the desired point and measure water quality at the correct depth. For this purpose, we constructed a water sampling lift and water sampling container, an unmanned vessel equipped with a VRS-GPS, an acoustic echo sounder, and a water quality sensor. Also, we developed an automatic navigation algorithm and program, an automatic water sampling program, and a water quality map generation program. As a result of the experiment in the detention pond, the unmanned vessel sailed along the planned route with an accuracy of about 93% within the error range of 3m. In addition, the water quality sensor installed in the lift was able to acquire the water quality of the target area in real time and transmit it to the server via wireless Internet, and it was possible to monitor the water quality of each site in real time. Through field experiments, the water sampling lift was able to control the desired length with an accuracy of about 94%. The stretch length accuracy experiment of the water sampling lift was impossible to measure directly in the water, so it was replaced land-based experiment. We also found some unstable problems due to the weight of the water sampling lift and the weight of the air compressor to operate the water container. Except these two problems, we accomplished purpose of this study. An automated water quality measurement method using an unmanned vessel can be used to measure the quality of water in a difficult to access area and to secure the safety of the worker.

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.4
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• pp.369-380
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• 2003

With the proliferation of a wireless support and the advances of mobile devices, there is a growing need of making it available for a wireless network as well. Low bandwidth of a wireless network is one of the major issues that should be considered for extending a synchronous collaboration system developed for a wired network to supuort a wireless network. We propose a priority-based view synchronization scheme, exploiting the relaxed synchronization. The proposed scheme leverages the fact that mobile users need not have the exactly same view as the users in a wired network since they usually have a limited screen size and thus focus only on part of a whole document. We evaluate the performance of a simple group editor with the propose scheme using ns -2. The performance results show that the proposed scheme keeps the message transmission delay low so that mobile users can have synchronous colloboration with wired users without signification delay. The proposed scheme is designed and implemented as a framework to support various kinds of realtime groupware applications, exploiting the existing groupware framework, Habanero. As a client program, we implemented a simple group text editor.

• Clinical and Experimental Pediatrics
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• v.53 no.5
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• pp.639-643
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• 2010

Purpose: Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have been reported. The clinical characteristics in children with neurologic manifestations of EV71 were studied in Ewha Womans University Mokdong Hospital. Methods: Examinations for EV71 were performed from the stools, respiratory secretion or CSF of children who presented neurologic symptoms associated with HFMD by realtime PCR. Clinical and radiologic data of the patients were collected and analyzed. Results: EV71 was isolated from the stool of 16 patients but not from respiratory secretion or CSF. Among the 16 patients, meningitis (n=10) was the most common manifestation, followed by Guillain-Barre syndrome (n=3), meningoencephalitis (n=2), poliomyelitis-like paralytic disease (n=1), and myoclonus (n=1). Gene analysis showed that most of them were caused by EV71 subgenotype C4a, which was prevalent in China in 2008. Conclusion: Because EV71 causes severe complications and death in children, a surveillance system to predict upcoming outbreaks should be established and maintained and adequate public health measures are needed to control disease.

• Proceedings of the Korea Contents Association Conference
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• 2004.11a
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• pp.327-332
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• 2004

USB(Universal Serial Bus) is one of the most popular communication interfaces. When USB is used in an extended range, especially configurating In-home network by connecting multiple digital devices each other, USB interface uses the bandwidth in the way of TDM(Time Division Multiplexing) so that the bottleneck of bus bandwidth can be brought. In this paper, the more effective usage of bus bandwidth to overcome this situation is introduced. Basically, in order to realize the system for transferring realtime moving picture data among digital information devices, we analyze USB transfer types and Descriptors and introduce the method to upgrade detailed performance of Isochronous transfer that is one of USB transfer types. In the case that Configuration descriptor of a device has Interface descriptor that has two AlternateSetting, if Isochronous transfers are not processed smoothly due to excessive bus traffic, the application of the device changes AlternateSetting of the Interface descriptor and requires a new configuration by SetInterface() request. As a result of this adaptive configuration, the least data frame rate is guaranteed to a device that the sufficient bandwidth is not alloted. And if the bus traffic is normal, the algorithm to return to the original AlteranteSetting is introduced. this introduced method resolve the bottleneck of moving picture transfer that can occur in home network connected by multiple digital devices.

• Journal of KIISE:Computer Systems and Theory
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• v.36 no.4
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• pp.274-282
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• 2009

Various location tracking sensors; such as GPS, INS, radar, and optical equipment; are used for tracking moving targets. In order to effectively track moving targets, it is necessary to develop an effective fusion method for these heterogeneous devices. There have been studies in which the estimated values of each sensors were regarded as different models and fused together, considering the different error characteristics of the sensors for the improvement of tracking performance using heterogeneous multi-sensor. However, the rate of errors for the estimated values of other sensors has increased, in that there has been a sharp increase in sensor errors and the attempts to change the estimated sensor values for the Sensor Probability could not be applied in real time. In this study, the Sensor Probability is obtained by comparing the RMSE (Root Mean Square Error) for the difference between the updated and measured values of the Kalman filter for each sensor. The process of substituting the new combined values for the Kalman filter input values for each sensor is excluded. There are improvements in both the real-time application of estimated sensor values, and the tracking performance for the areas in which the sensor performance has rapidly decreased. The proposed algorithm adds the error characteristic of each sensor as a conditional probability value, and ensures greater accuracy by performing the track fusion with the sensors with the most reliable performance. The trajectory of a UAV is generated in an experiment and a performance analysis is conducted with other fusion algorithms.

• The Journal of the Korea Contents Association
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• v.7 no.2
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• pp.117-124
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• 2007

This paper describes methodology that enables animators to create the facial expression animations and to control the facial expressions in real-time by reusing motion capture datas. In order to achieve this, we fix a facial expression state expression method to express facial states based on facial motion data. In addition, by distributing facial expressions into intuitive space using LLE algorithm, it is possible to create the animations or to control the expressions in real-time from facial expression space using user interface. In this paper, approximately 2400 facial expression frames are used to generate facial expression space. In addition, by navigating facial expression space projected on the 2-dimensional plane, it is possible to create the animations or to control the expressions of 3-dimensional avatars in real-time by selecting a series of expressions from facial expression space. In order to distribute approximately 2400 facial expression data into intuitional space, there is need to represents the state of each expressions from facial expression frames. In order to achieve this, the distance matrix that presents the distances between pairs of feature points on the faces, is used. In order to distribute this datas, LLE algorithm is used for visualization in 2-dimensional plane. Animators are told to control facial expressions or to create animations when using the user interface of this system. This paper evaluates the results of the experiment.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.39 no.4
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• pp.355-355
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• 2002

In this paper, we designed a FPU(floating point unit) that it is very important and requires of high density when digital audio is designed. Almost audio system must support the multi-channel and required for high quality. A floating point arithmetic function in MPEG-2 AAC that implemented by hardware is able to realtime decoding when DSP realization. The reason is that MPEG-2 AAC is compatible to the Audio field of MPEG-4 and afterwards. We designed a FPU by hardware to increase the speed of a floating point unit with much calculation part in the MPEG-2 AAC Decoder. A FPU is composed of a multiplier and an adder. A multiplier used the Radix-4 Booth algorithm and an adder adopted 1's complement method for speed up. A form of a floating point unit has 8bit of exponent part and 24bit of mantissa. It's compatible with the IEEE single precision format and adopted a pipeline architecture to increase the speed of a processor. All of sub blocks are based on ISO/IEC 13818-7 standard. The algorithm is tested by C language and the design does by use of VHDL(VHSIC Hardware Description Language). The maximum operation speed is 23.2MHz and the stable operation speed is 19MHz.

• Spatial Information Research
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• v.20 no.1
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• pp.91-103
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• 2012

Recently, there has been much interest in the middleware that can smoothly acquire and analyze Geosensor information which includes sensor readings, location, and its surrounding spatial information. In relation to development of the middleware, researchers have proposed various algorithms for energy-efficient information filtering in Geosensor networks and have proposed Geosensor web technologies which can efficiently mash up sensor readings with spatial information on the web, also. The filtering algorithms and Geosensor Web technologies have contributions on energy-efficiency and OpenAPI, however the algorithms and technologies could not support easy and rapid development of u-GIS applications that need various Geosensor networks. Therefore, we propose a new Geosensor network middleware that can dramatically reduce the time and cost required for development of u-GIS applications that integrate heterogeneous Geosensor networks. The proposed middleware has several merits of being capable of acquiring heterogeneous Geosensor information using the standard SWE and an extended SQL, optimally performing various attribute and spatial operators, and easily integrating various Geosensor networks. Finally, we clarify our middleware's distinguished features by developing a prototype that can monitor environmental information in realtime using spatial information and various sensor readings of temperature, humidity, illumination, imagery, and location.