• Korean Journal of Radiology
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• v.20 no.1
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• pp.114-125
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• 2019

Objective: Segmented cardiac cine magnetic resonance imaging (MRI) is the gold standard for cardiac ventricular volumetric assessment. In patients with difficulty in breath-holding or arrhythmia, this technique may generate images with inadequate quality for diagnosis. Real-time cardiac cine MRI has been developed to address this limitation. We aimed to assess the performance of retrospective electrocardiography-gated real-time cine MRI at 3T for left ventricular (LV) volume and mass measurement. Materials and Methods: Fifty-one patients were consecutively enrolled. A series of short-axis cine images covering the entire left ventricle using both segmented and real-time balanced steady-state free precession cardiac cine MRI were obtained. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), and LV mass were measured. The agreement and correlation of the parameters were assessed. Additionally, image quality was evaluated using European CMR Registry (Euro-CMR) score and structure visibility rating. Results: In patients without difficulty in breath-holding or arrhythmia, no significant difference was found in Euro-CMR score between the two techniques (0.3 ± 0.7 vs. 0.3 ± 0.5, p > 0.05). Good agreements and correlations were found between the techniques for measuring EDV, ESV, EF, SV, and LV mass. In patients with difficulty in breath-holding or arrhythmia, segmented cine MRI had a significant higher Euro-CMR score (2.3 ± 1.2 vs. 0.4 ± 0.5, p < 0.001). Conclusion: Real-time cine MRI at 3T allowed the assessment of LV volume with high accuracy and showed a significantly better image quality compared to that of segmented cine MRI in patients with difficulty in breath-holding and arrhythmia.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.12
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• pp.3202-3218
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• 1994

Mode shapes and natural frequencies of vibrating laminated composite plates are taken using real-time and time-average holographic interferometry. Debonds and delamination in the laminated plates are measured nondestructively. During holographic testing of composite plates, it has been found that the conditions for the local resonance in debonds are strongly dependent on the frequency of excitation. A membrane resonance model was proposed to describe this behavior. Relations between characteristic length according to the size, shape of debonds and membrane resonance frequency are presented. Several experiments were performed to verify the membrane resonance model. The agreements between the predicted excitation frequency and the observed resonance frequency are good. The experimental results show that higher stresses and strains due to local resonance lead to the debond detection.

• Journal of the Korean Magnetic Resonance Society
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• v.19 no.3
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• pp.124-131
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• 2015

Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low ${\gamma}$ nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.67-72
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• 2002

Real-time techniques are motivated by a number of factors including the potential for direct acquisition of diagnostic quality images, facilitation of patient-specific imaging parameters, and reduced examination time. Real-time MRI includes not only a rapid pulse sequence but also high speed image reconstruction and easy interactivity. The frame rate of the real-time technique used should be matched to the physiological timeframes under study. Principal applications thusfar have been in localization, fluoroscopic triggering, guidance of other processes, and potentially in the generation of diagnostic images of moving structures.

• Investigative Magnetic Resonance Imaging
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• v.25 no.4
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• pp.252-265
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• 2021

Cardiac magnetic resonance imaging (MRI) serves as a clinical gold-standard non-invasive imaging technique for the assessment of global and regional cardiac function. Conventional cardiac MRI is limited by the long acquisition time, the need for ECG gating and/or long breathhold, and insufficient spatiotemporal resolution. Real-time cardiac cine MRI refers to high spatiotemporal cardiac imaging using data acquired continuously without synchronization or binning, and therefore of potential interest in overcoming the limitations of conventional cardiac MRI. Novel acquisition and reconstruction techniques must be employed to facilitate real-time cardiac MRI. The goal of this study is to discuss methods that have been developed for real-time cardiac MRI. In particular, we classified existing techniques into two categories based on the use of non-iterative and iterative reconstruction. In addition, we present several research trends in this direction, including deep learning-based image reconstruction and other advanced real-time cardiac MRI strategies that reconstruct images acquired from real-time free-breathing techniques.

• BMB Reports
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• v.34 no.5
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• pp.452-456
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• 2001

Surface plasmon resonance has been used for a biospecific interaction analysis between two macromolecules in real time. Determination of an antibody that is capable of specifically interacting with the native form of antigen is very useful for many biological and medical applications. Twenty monoclonal antibodies against the $\alpha$ subunit of E. coli DNA polymerase III were screened for specifically recognizing the native form of protein using surface plasmon resonance. Only four monoclonal antibodies among them specifically recognized the native $\alpha$ protein, although all of the antibodies were able to specifically interact with the denatured $\alpha$ subunit. These antibodies failed to interfere with the interaction between the $\tau$ and $\alpha$ subunits that were required for dimerization of the two polymerases at the DNA replication fork. This real-time analysis using surface plasmon resonance provides an easy method to screen antibodies that are capable of binding to the native form of the antigen molecule and determine the biological interaction between the two molecules.

• Bulletin of the Korean Chemical Society
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• v.17 no.2
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• pp.198-200
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• 1996

The resonance width may be directly determined by solving an eigenvalue equation for width operator which is derived in this work based on the method of complex scaling transformation. The width operator approach is advantageous to the conventional rotating coordinate method in twofold; 1) calculation can be done in real arithmetics and, 2) so-called θ-trajectory is not required for determining the resonance widths. Application to one- and two-dimensional model problems can be easily implemented.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.29 no.4
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• pp.62-68
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• 2015

Subsynchronous Resonance is a condition where the electrical power systems composed of generator and transmission line exchange energy with mechanical turbine-generator system at the frequency of the combined below the subsynchronous frequency. Therefore, the frequency of power systems should be associated with the subsynchronous resonance. This paper describes subsynchronous resonance by flexible frequency operation. It focuses on the characteristics and behavior of subsynchronous resonance. The subsynchronous resonance is being conducted by real-time digital simulator and the IEEE benchmark model for subsynchronous resonance have been utilized for the test systems.

• Journal of Mechanical Science and Technology
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• v.14 no.7
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• pp.744-751
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• 2000

To achieve lower flying height for high areal recording density, the laser zone texturing of the disk needs to be designed to reduce glide height. One problem of the laser bump design is that the regular laser bump pattern often produces glide resonance phenomenon, which leads to failure of the glide height test. However, it was found in this study that glide resonance is an intrinsic problem of the glide head used and resonance phenomenon depends on the type of the head slider, that is, the natural frequency of the slider body. Therefore, higher glide height or glide failure caused by glide resonance does not lead to head/media interface problem in the real drive operating conditions in which the data head is used. Pseudo-random bump pattern greatly reduces the glide resonance. Smaller bump pitch will also help to reduce the glide resonance. However, as bump spacing becomes smaller, glide height will be increased due to increased air pressure developed around the bumps. Lowering bump height is the most effect way to reduce glide avalanche.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.15-19
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• 2008

This research was conducted to develop a quick and sensitive method of detecting carbamate residues using the immobilization of antibody-antigen interactions with surface plasmon resonance (SPR). We have used commercialized surface plasmon resonance equipment (Biacore 3000). The antibody used for the immunoassay was specific for glutathione-s-transferase (GST) and the antigens included several carbamate pesticides (carbofuran, carbaryl, and benfuracarb). When antigens were applied to the protein GST, the detection limit was 2 ng/mL of carbamate pesticide. The fabricated protein GST maintained its activity for over 200 measurements. Thus we determined that the SPR biosensors could detect the specific reversible binding of a reactant in solution to a binding partner immobilized on the surface of the sensor and allow real-time detection and monitoring.