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http://dx.doi.org/10.6564/JKMRS.2015.19.3.124

Hyperpolarization: Sensitivity Boost in Magnetic Resonance Spectroscopy and Imaging  

Ko, Hyeji (Department of Applied Chemistry, Hanyang University)
Gong, Gyeonghyeon (Department of Applied Chemistry, Hanyang University)
Jeong, Gijin (Department of Applied Chemistry, Hanyang University)
Choi, Ikjang (Department of Applied Chemistry, Hanyang University)
Seo, Hyeonglim (Department of Applied Chemistry, Hanyang University)
Lee, Youngbok (Department of Applied Chemistry, Hanyang University)
Publication Information
Journal of the Korean Magnetic Resonance Society / v.19, no.3, 2015 , pp. 124-131 More about this Journal
Abstract
Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low ${\gamma}$ nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.
Keywords
Hyperpolarization; dissolution DNP; MRS; MRI; real-time measurement;
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