Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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Hyperpolarization: Sensitivity Boost in Magnetic Resonance Spectroscopy and Imaging

  • Ko, Hyeji (Department of Applied Chemistry, Hanyang University) ;
  • Gong, Gyeonghyeon (Department of Applied Chemistry, Hanyang University) ;
  • Jeong, Gijin (Department of Applied Chemistry, Hanyang University) ;
  • Choi, Ikjang (Department of Applied Chemistry, Hanyang University) ;
  • Seo, Hyeonglim (Department of Applied Chemistry, Hanyang University) ;
  • Lee, Youngbok (Department of Applied Chemistry, Hanyang University)
  • Received : 2015.09.12
  • Accepted : 2015.11.25
  • Published : 2015.12.20
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Abstract

Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low ${\gamma}$ nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.

Keywords

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