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Development of Program for Relative Biological Effectiveness (RBE) Analysis of Particle Beam Therapy

  • Chung, Yoonsun;Ahn, Sang Hee;Choi, Changhoon;Park, Sohee
    • Progress in Medical Physics
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    • v.28 no.1
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    • pp.11-15
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    • 2017
  • Relative biological effectiveness (RBE) of particle beam needs to be evaluated at particle beam therapy centers before the clinical application of the particle beam. However, since RBE analysis is implemented manually, it is useful to have a tool that can easily and effectively handle the data of experiments to generate cell survival curve and to analyze RBE simultaneously. In this work, the development of a program for RBE analysis of particle beam therapy was presented. This RBE analysis program was developed to include two parts; fitting the cell survival curves to linear-quadratic model and calculating the RBE values at a certain endpoint using fitting results. This program was also developed to simultaneously compare and analyze the template results that stored experiment data with photon and particle beam irradiations. The results of the cell survival curve obtained by each irradiation can be analyzed by the user on a desired data after reading the template stored in the easy-to-use excel file. The analysis results include the cell survival curves with error range, which are appeared in the screen and the ${\alpha}$ and ${\beta}$ parameters of linear-quadratic model with 95% confidence intervals, RBE values, and $R^2$ values to evaluate goodness-of-fit of survival curves to model, which are stored in a text cvs file. This software can generate cell survival curve, fit to model, and calculate RBE all at once with raw experiment data, so it helps users to save time for data handling and to reduce the possibility of making error on analysis. As a coming plan, we will create a user-friendly graphical user interface to present the results more intuitively.

Implementation of Digital Mammogram CAD Algorithm (디지털 유방영상의 CAD 알고리즘 구현)

  • Lee, Byungchea;Choi, Guirack;Jung, Jaeeun;Lee, Sangbock
    • Journal of the Korean Society of Radiology
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    • v.8 no.1
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    • pp.27-33
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    • 2014
  • Medical imaging has increased rapidly in the increase of interest in health, with the development of computer technology, digitization of medical imaging is rapidly advancing, PACS has been introduced to the medical field. Increase in the production of medical images by these phenomena made increased the workload of radiologist who must read a medical image. in response to the need for secondary diagnosis using a computer, The term of CAD in medical radiology field was introduced. In this study, we have proposed a CAD algorithm for the interpretation of the image obtained by the digital X-ray mammography equipment. The experiments were performed by programmed in Visual C++ for the proposed algorithm. A result of the execution of the CAD algorithm seven sample images, the results of five samples was confirmed in breast cancer and benign tumors, both the images sample was error processing. If you use a program that implements this with the algorithm proposed in this study it is helpful to reading breast images, and it is considered to contribute significantly to the early detection of breast cancer.

FPGA Design and Sync-Word Detection of CATV Down-Link Stream Transmission System (CATV 하향 스트림 적용 시스템에서 동기 검출 방안 및 FPGA 설계)

  • Jung, Ji-Won
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.4 no.4
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    • pp.286-294
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    • 2011
  • Cable modems typically are implemented by a forward error correction(FEC) scheme. The ITU-T Recommendation J-38 Annex B specifies using 64- and 256- quadrature amplitude modulation (QAM) and extended RS coding scheme. In implementing the cable modem, there are some problems to fabricate and fitting on FPGA chip. First, many clocks are needed in implementing cable modem because of different code rate and different modulation types. To reduce the number of clocks, we use the two memories, which are different clock speed for reading and writing data. Second, this system lost the bit-synchronization and frame-synchronization in decoder, the system recognize that all data is error. This paper solves the problems by using simple 5-stage registers and unique sync-word. Based on solutions for about problems, the cable modem is fabricated on FPGA chip name as Vertex II pro xc2vp30-5 by Xilinx, and we confirmed the effectiveness of the results.

Pig Image Learning for Improving Weight Measurement Accuracy

  • Jonghee Lee;Seonwoo Park;Gipou Nam;Jinwook Jang;Sungho Lee
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.7
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    • pp.33-40
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    • 2024
  • The live weight of livestock is important information for managing their health and housing conditions, and it can be used to determine the optimal amount of feed and the timing of shipment. In general, it takes a lot of human resources and time to weigh livestock using a scale, and it is not easy to measure each stage of growth, which prevents effective breeding methods such as feeding amount control from being applied. In this paper, we aims to improve the accuracy of weight measurement of piglets, weaned pigs, nursery pigs, and fattening pigs by collecting, analyzing, learning, and predicting video and image data in animal husbandry and pig farming. For this purpose, we trained using Pytorch, YOLO(you only look once) 5 model, and Scikit Learn library and found that the actual and prediction graphs showed a similar flow with a of RMSE(root mean square error) 0.4%. and MAPE(mean absolute percentage error) 0.2%. It can be utilized in the mammalian pig, weaning pig, nursery pig, and fattening pig sections. The accuracy is expected to be continuously improved based on variously trained image and video data and actual measured weight data. It is expected that efficient breeding management will be possible by predicting the production of pigs by part through video reading in the future.

Precision evaluation of the treatment that used coordinates confirmation of couch in case of two forgets adjoined. (Couch의 좌표 확인을 이용한 치료 위치 이동의 정확성 평가)

  • Seo Jeong-min;Jeong Cheon-young;Park Young-hwan;Song Ki-won
    • The Journal of Korean Society for Radiation Therapy
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    • v.15 no.1
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    • pp.35-40
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    • 2003
  • I. Purpose Confirming an error to be able to break out in a method to move couch manually while operator sees the skin marks on patient in case of curing head who got 2 targets adjoined, so we analyze coordinates price of couch, evaluate reproducibility and precision of change movements between targets. II. Materials and Methods In radiotherapy, for confirming errors in manual movements by operators by exchanging between two targets to treat patient head, we read coordinates price(vertical, longitudinal, lateral three directions of couch) shown on a monitor of LINAC( CL 2100, Varian, USA) in order to evaluate accuracy about the length that moved in time for moving couch manually. After reading movement length of coordinates recorded in three directions of all treatment, we compared distance between targets recorded in RTP(Pinnacle, ADAC, USA) with reading coordinates price of couch, setting actually done the same patient for ten times, coordinates were recorded, treated for evaluating averages and degrees of errors and standard deviations. III. Results In method to confirm skin marks of patient by operators' view and to move couch manually, average standard deviations of movements between two targets are vertical 1.4mm, longitudinal 0.9mm, lateral 2.2mm in each direction. As for the error in straight dimension, it is about 3.6mm averages and 5.1mm maximum. The average of errors in each directions was vertical 1mm, longitudinal 0.7mm, lateral 2.7mm. The greatest error broke out in lateral direction with $25\%$ of all cases ; to exceed an error average. IV. Conclusions If operators moved manually couch for changing target points, errors about 3.6mm average degrees occur. It is important that operators confirm the errors prices of actual couch coordinates for asking a correct movement between the targets adjoined each other ; in case of treatment demanding high precision like 3D conformal therapy or IMRT. Therefore, if we apply couch coordinates confirmation to reproducibility and to precision evaluation of treatment, it's expected that we can execute high-quality radiotherapy.

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Application of Digital Signal Analysis Technique to Enhance the Quality of Tracer Gas Measurements in IAQ Model Tests

  • Lee, Hee-Kwan;Awbi, Hazim B.
    • Journal of Korean Society for Atmospheric Environment
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    • v.23 no.E2
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    • pp.66-73
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    • 2007
  • The introduction of tracer gas techniques to ventilation studies in indoor environments provides valuable information that used to be unattainable from conventional testing environments. Data acquisition systems (DASs) containing analogue-to-digital (A/D) converters are usually used to function the key role that records signals to storage in digital format. In the testing process, there exist a number of components in the measuring equipment which may produce system-based inference to the monitored results. These unwanted fluctuations may cause significant error in data analysis, especially when non-linear algorithms are involved. In this study, a pre-processor is developed and applied to separate the unwanted fluctuations (noise or interference) in raw measurements and to reduce the uncertainty in the measurement. Moving average, notch filter, FIR (Finite Impulse Response) filters, and IIR (Infinite Impulse Response) filters are designed and applied to collect the desired information from the raw measurements. Tracer gas concentrations are monitored during leakage and ventilation tests in the model test room. The signal analysis functions are introduced to carry out the digital signal processing (DSP) work. Overall the FIR filters process the $CO_2$ measurement properly for ventilation rate and mean age of air calculations. It is found that, the Kaiser filter was the most applicable digital filter for pre-processing the tracer gas measurements. Although the IIR filters help to reduce the random noise in the data, they cause considerable changes to the filtered data, which is not desirable.

A Study on the Technology Measuring Partial Discharge for Long Term Aging Experiments of Insulation Materials (장시간 절연체 열화실험을 위한 부분방전측정기술 연구)

  • Seon, Jong-Ho;Kim, Gwang-Hwa;Park, Jeong-Hu;Jo, Jeong-Su
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.49 no.12
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    • pp.665-672
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    • 2000
  • This paper described the measurement technology to analyze the partial discharge characteristics for long term aging of insulations. This system was consisted of high voltage generation and measurement part, PD detection part, digital conversion and signal processing part. We used the VXI system for digital conversion and signal processing part. In the digital conversion part, we studied the error of partial discharge magnitude and memory capacity for reading digital signal with the sampling rate. In the signal processing part, we showed the program algorithm to count pulses and read peak values of partial discharge. The allowable minimum sampling rate of digizer was decided to 250kS/s through analyzing test. We confirmed that this system was very useful in the study of $\phi-q-n$ characteristics of long term PD experiments with specimens being consisted of internal void defects and CIGRE II electrodes.

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A Study of Front-end System for BD Recorder (BD 기록기를 위한 전단 시스템에 관한 연구)

  • Choi, Goang-Seog
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.6 s.360
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    • pp.28-33
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    • 2007
  • The front-end system having a capable of 2x reading and writing of BD-R/Ra/ROM is developed. Its readability is improved by adopting 5-tap adaptive partial response maximum likelihood (PRML) with the PR(a,b,c,d,e) type channel. Due to the proposed PRML, less than $2{\times}10^{-4}$ of the bit error rate (BER) is achieved with radial and tangential tilt margin of over${\mp}0.6{\circ}$ on 25GB disc in 2x speed. The method of an optimum Power control (OPC) for stable writing of various BD-R/RE is proposed. The developed chip contains 14-million transistors in a $60mm^2$ dies, and is fabricated in $0.18-{\mu}m$ CMOS technology.

The Recording Time Schedule in the Phase-Code Multiplexing System (위상부호 홀로그램 중첩 시스템에서 홀로그램의 중첩저장 및 복원을 위한 기록시간 분배)

  • 김유현;손승대;이연호
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.40 no.2
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    • pp.88-97
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    • 2003
  • Computer simulations of the recording and reading of holograms in an 8-bit phase-code multiplexing system are presented. From the computer simulation each recording time of eight holograms is obtained such that the strength of restored holograms is same. An analytic formula to predict the recording times is derived by fitting the formula to the computer simulation data. It is found that our analytic formula can predict the hologram recording time not only in 8-bit system but also in 16-bit and 32-bit systems in an error less than $\pm$8.4%. Optical experiments are also performed in a 4-bit phase code-multiplexing system. It is found that the strength of the restored holograms is more uniform compared with conventional methods.

Analysis in Technological Responses to Side-channel Attack (부채널 공격에 대한 대응기술 분석)

  • d, Young-Jin;Jo, JungBok;Lee, HoonJae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.05a
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    • pp.219-222
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    • 2013
  • The Side Channel attack methods proposed by P.Kocher are mainly used for cryptanalysis different cipher algorithms even though they are claimed to be strongly secured. Those kinds of attacks depend on environment implementation especially on the hardware implementation of the algorithm to the crypto module. side-channel attacks are a type of attack introduced by P.Kocher and is applicable according to each environment or method that is designed. This kind of attack can analyze and also extract important information by reading the binary code data via measurement of changes in electricity(voltage) consumption, running time, error output and sounds. Thus, in this paper, we discuss recent SPA and DPA attacks as well as recent countermeasure techniques.

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