• 제목/요약/키워드: Reaction parameter

검색결과 477건 처리시간 0.024초

관상동맥의 기하학적 형상변화에 따른 동맥경화 위험도 (Atherogenic Risk Stratification According to Changes in the Geometrical Shape of the Coronary Artery)

  • 서상호;박준길;노형운;이병권;권혁문
    • 대한기계학회논문집B
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    • 제34권10호
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    • pp.893-899
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    • 2010
  • 박동유동조건에서 관상동맥 내의 유동특성과 혈류역학적 인자 분포를 선행연구에서 수행하여 혈류역학이 관상동맥 내의 협착현상과 연관관계가 있음을 밝혔다. 동맥경화증의 호발부위인 관상동맥 분지부에서 혈류역학적 변수를 분석하여 동맥경화증의 발생기전을 규명하는 것이 본 연구의 목적이다. 동맥경화증에 의한 협착현상은 혈액과 혈관벽 사이의 생화학 반응뿐 아니라 유동박리나 벽전단응력과 같은 혈류역학적 인자와도 관계 있음을 확인하였다. 관상동맥 분지부의 분지각이 증가할수록 분지부 단면에서의 재순환영역의 크기가 증가하고 교란유동이 발생하게 된다. 이 재순환영역이 관상동맥에서 동맥경화의 시작점으로 의심되는 영역이라 할 수 있다.

Genetic Variation of the Mitochondrial Cytochrome b Sequence in Korean Rana rugosa (Amphibia; Ranidae)

  • Hyun Ick Lee;Dong Eun Yang;Yu Ri Kim;Hyuk Lee;Jung Eun Lee;Suh Yung Yang;Hei Yung Lee
    • Animal cells and systems
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    • 제3권1호
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    • pp.89-96
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    • 1999
  • Nucleotide sequences of a 501 base-pair (bp) fragment in the mitochondrial cytochrome b (cyt b) gene were analyzed for 12 populations of Rana rugosa from Korea and Japan using a polymerase chain reaction (PCR) and direct silver sequencing. Two genetically distinct groups (type-A and type-B) were found in Korea. Type-A was found throughout most of South Korea and type-B was restricted to the mid-southeastern regions (Samchok, Yongdok, Chongsong and Pohang). But in the Tonghae population, both types were found. The level of mitochondrial DNA (mtDNA) sequence differences ranged from 0% to .0.8% among six populations of type-A, and 0 to 1.0% among 4 populations of type-B. However, sequence differences between type-A and type-B ranged from 5.4% to 6.6%, Using Kimura's two-parameter distance, the level of genetic sequence divergence between type-A and type-B was 6.7%. The Japanese R. rugosa was clustered very far from the Korean R. rugosa with 14.7%. In the neighbor-joining and UPGMA tree, all Korean samples were grouped, but subdivided into two types in 99% of the bootstrap iteration.

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Racemic and enantiomeric effect of tartaric acid on the hydrophilicity of polysulfone membrane

  • Sharma, Nilay;Purkait, Mihir Kumar
    • Membrane and Water Treatment
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    • 제7권3호
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    • pp.257-275
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    • 2016
  • The enantiomeric and racemic effects of tartaric acid (TA) on the properties of polysulfone (PSn) ultrafiltration membranes were studied in terms of morphology and hydrophilicity (HPCT) of membrane. Asymmetric membranes were prepared by direct blending of polyvinyl pyrrolidone (PVP) with D-TA and DL-TA in membrane casting solution. FTIR analysis was done for the confirmation of the reaction of PVP and TA in blended membranes and plain PSn membranes. Scanning electron microscope (SEM), field emission scanning electron microscope (FESEM) and atomic force microscopy (AFM) were used for analyzing the morphology and structure of the resulting membranes. The membranes were characterized in terms of pure water flux (PWF), hydraulic permeability and HPCT. PWF increased from $52L/m^2h$ to $79.9L/m^2h$ for plain and D-TA containing PSn membrane, respectively. Water contact angle also found to be decreased from $68^{\circ}$ to $55^{\circ}$. In Additionally, permeation and rejection behavior of prepared membranes was studied by bovine serum albumin (BSA) solution. A considerable increase in BSA flux (from $19.1L/m^2h$ for plain membrane to $32.1L/m^2h$ for D-TA containing membrane) was observed. FESEM images affirm that the pore size of the membranes decreases and the membrane permeability increases from 0.16 to 0.32 by the addition of D-TA in the membrane. D-TA increases the HPCT whereas; DL-TA decreases the HPCT of PSn membrane. PVP (average molecular weight of 40000 Da) with D-TA (1 wt%) gave best performance among all the membranes for each parameter.

Fast Neutron Dosimetry with Two Threshold Detectors in Criticality Accidents of Nuclear Reactors

  • Ro, Seung-Gy
    • Nuclear Engineering and Technology
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    • 제2권2호
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    • pp.85-95
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    • 1970
  • 두개의 threshold detector로서 인자로의 폭발사고시에 방출되는 속 중성자의 속도분포를 측정하고 그로부터 속 중성자의 인체흡수선량을 계산하였다. 이때 속 중성자의 속도분포는 하나의 스펙트럼 매개변수에 의하여 결정된다는 가정으로부터 얻어지는데 이 매개변수는 threshold detector의 반응율을 측정하므로서 구해진다. 속 중성자의 인체흡수선량은 속 중성자의 속도분포 변화에 따라 큰 변동이 없었으나 threshold detector의 평균반응단면적은 크게 변하였다. 따라서 속 중성자의 속도분포에 관계없이 threshold detector의 평균반응단면적을 고정된 값으로 취하여 속 중성자선량을 계산한다면 큰 오차를 일으키게 될 것이라는 것을 보여주었다. 한편 핵분열에서 방출되는 속 중성자의 속도분포에 대한 세 해석적 표현인 즉 Watt, Cranberg및 Maxwellian 공식들로부터 속 중성자 선량을 계산하여 서로 비교하였다. Watt 및 Cranberg 공식들로 부터 얻어진 속 중성자선량은 Maxwellian 공식으로부터 얻어진 그것보다 약간 높은 값을 보여 주었으며 Watt 공식에 의한 선량계산치는 Cranberg 공식에 의한 그것과 비슷한 값을 보여주었다.

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Biphenyl Dimethyl Dicarboxylate가 간내 Cytochrome $P_{450}$ 1A1과 2Bl 및 $CCl_4$ 유도 간독성에 미치는 영향 (Effect of Biphenyl Dimethyl Dicarboxylate on Cytochrome $P_{450}$ 1A1 and 2B1 and ${CCl_4}-Induced$ Hepatotoxicity in Rat Liver)

  • 김순선;오현영;김학림;양지선;김동섭;신윤용;최기환
    • 약학회지
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    • 제43권6호
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    • pp.827-833
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    • 1999
  • In this study, we have investigated the effect of Biphenyl Dimethyl Dicarboxylate (DDB), a synthetic analogue of Schizandrin C isolated from Schizandrae Fructus on cytochrome $P_450$ lAl and 2Bl, and the protective mechanism against $CCl_4-induced$ hepatotoxicity in rat liver. After DDB was administered into male rats for different periods of time (1~7 days) and with different doses (25, 50, 100 and 200 mg/kg), mRNA levels of CYPlAl were measured by polymearse chain reaction (PCR) and assayed the activities of CYPlAl specific ethoxyresorufin-O-dealkylase (EROD) and CYP2Bl specific benzyloxyresorufin-O-dealkylase (BROD). DDB treatment resulted in increase in CYP2Bl mRNA level and BROD activity, whereas there was no change in CYPlAl mRNA level and EROD activity. This effect of DDB was time-and dose-dependent and reached maximal level by 3 day and 200 mg/kg treatment. In addition, rats were pre-treated with DDB at doses of 25, 50 or 100 mg/kg daily for 4 days, 3-hr after final treatment on the 4th day, $CCl_4$ 0.3ml/kg was intraperitonially injected into the rats to examine the effect of DDB on $CCl_4-induced$ hepatic injury. Serum levels of ALT and AST were determined and histopathological examination was done in rat liver. Furthermore, we have measured hepatic microsomal malondialdehyde(MDA) level, a parameter of lipid peroxidation. Based on serum ALT level and lipid peroxidation, pretreatment of DDB, 50 mg/kg appeared the most protective effect against $CCl_4-induced$ heapatotoxity. These results indicate that DDB stimulates CYP2Bl mRNA level and BROD activity in time and dose dependent manner and suggest that protective effect of DDB on $CCl_4-induced$ hepatotoxicity may be mediated through free radical scavenging.

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Reliability and validity of pelvic mobility measurement using a cushion sensor in healthy adults

  • Jung, Seung-Hwa;Kim, Su-Kyeong;Lee, Ji-Hyun;Choi, Soo-Ih;Park, Dae-Sung
    • Physical Therapy Rehabilitation Science
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    • 제9권2호
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    • pp.74-81
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    • 2020
  • Objective: To prevent low back pain, an objective evaluation tool to evaluate pelvic mobility and exercise to improve the flexibility of the lumbar region is needed. The purpose of this study was to compare the results of pelvic mobility measurements using the Wii Balance Board (WBB) and Sensbalance Therapy Cushion (STC), evaluate the usefulness of the STC as a tool for measuring pelvic mobility. Design: Cross-sectional study. Methods: Fifty healthy subjects participated in this study. The subjects performed pelvic mobility range, proprioception, reaction time and reach of the arm using the STC. The pelvic movement parameter was measured two times to determine the intra-rater reliability. To measure the correlation between lumbar muscle tension and pelvic mobility, Myovision was used to measure tension of L4, L5 level erector spinae muscle. Correlations between measured variables were checked to determine the validity of the pelvic mobility assessment tool. Results: STC showed high test-retest reliability in pelvic tilt measurement and reaching task [intraclass correlation coefficients (3,1)=0.804-0.915]. The relationship between WBB and STC showed a significant positive correlation with the pelvic tilt and reaching task (p<0.05). Posterior tilt and erector spinae activation (Lt. L5) showed a significant negative correlation (p<0.05). Left, right tilt and erector spinae activation (L5) showed a significant negative correlation (p<0.05). Conclusions: This study confirmed the advantages of the STC and found efficiency as an objective measuring device of pelvic mobility.

염산용액(鹽酸溶液)에서 白金(IV), 팔라듐(II)과 로듐(III)의 이온평형(平衡) (Ionic Equilibria of Pt(IV), Pd(II) and Rh(III) in Hydrochloric Acid Solution)

  • 이만승;이진영
    • 자원리싸이클링
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    • 제18권1호
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    • pp.30-37
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    • 2009
  • 염산농도 0.001에서 10 M사이의 범위에서 백금(IV)과 팔라듐(II) 및 로듐(III)의 착물형성반응과 물질수지를 고려하여 각 금속의 분배곡선을 구했다. 염산농도가 0.1 M이상인 조건에서는 백금과 팔라듐의 대부분은 $PtCl_6^{2-}$$PdCl_2^{2-}$로 존재하였다. 로듐의 농도분포는 염산농도에 큰 영향을 받는다. 염산농도가 0.1에서 10 M로 증가함에 따라 로듐의 주 화학종이 $PhCl_5^{2-}$에서 $PhCl_6^{3-}$로 변했다. 문헌에 발표된 백금과 팔라듐의 용매추출자료로부터 $PtCl_6^{2-}$$PtCl_4^{2-}$와 수소이온간의 매개변수를 추산했다.

Spectroscopic Ellipsometry of Si/graded-$Si_{1-x}Ge_x$/Si Heterostructure Films Grown by Reduced Pressure Chemical Vapor Deposition

  • Seo, J.J.;Choi, S.S.;Yang, H.D.;Kim, J.Y.;Yang, J.W.;Han, T.H.;Cho, D.H.;Shim, K.H.
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 하계학술대회 논문집 Vol.7
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    • pp.190-191
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    • 2006
  • We have investigated optical properties of Si/graded-$Si_{1-x}Ge_x$/Si heterostructures grown by reduced pressure chemical vapor deposition. Compared to standard condition using Si(100) substrate and growth temperature of $650^{\circ}C$, Si(111) resulted in low growth rate and high Ge mole fraction. Also samples grown at higher temperatures exhibited increased growth rate and reduced Ge mole fraction. The features regarding both substrate temperature and crystal orientation, representing high incorporation of silicon supplied from gas stream played as a key parameter, illustrate that reaction control were prevailed in this process growth condition. Using secondary ion mass spectroscopy and spectroscopic ellipsometry, microscopic changes in atomic components could be analyzed for Si/graded-$Si_{1-x}Ge_x$/Si heterostructures.

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Performance evaluation of organic matter adsorption from actual graywater using GAC: OrbitrapTM MS and optimization

  • Ligaray, Mayzonee;Kim, Minjeong;Shim, Jaegyu;Park, Jongkwan;Cho, Kyung Hwa
    • Membrane and Water Treatment
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    • 제10권6호
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    • pp.471-484
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    • 2019
  • The complex combination of organic contaminants in the wastewater made water treatment challenging; hence, organic matter in water bodies is usually measured in terms of organic carbon. Since it is important to identify the types of compounds when deciding suitable treatment methods, this study implemented a quantitative and qualitative analysis of the organic matter content in an actual graywater sample from Ulsan, Republic of Korea using mass spectroscopy (MS). The graywater was treated using adsorption to remove the organic contaminants. Using orbitrap MS, the organic matter content between an untreated graywater and the treated effluent were compared which yielded a significant formula count difference for the samples. It was revealed that CHON formula has the highest removal count. Isotherm studies found that the Freundlich equation was the best fit with a coefficient of determination ($R^2$) of 0.9705 indicating a heterogenous GAC surface with a multilayer characteristic. Kinetics experiments fit the pseudo-second order equation with an $R^2$ of 0.9998 implying that chemisorption is the rate-determining step between the organic compounds and GAC at rate constant of $52.53g/mg{\cdot}h$. At low temperatures, the reaction between GAC and organic compounds were found to be spontaneous and exothermic. The conditions for optimization were set to achieve a maximum DOC and TN removal which yielded removal percentages of 94.59% and 80.75% for the DOC and TN, respectively. The optimum parameter values are the following: pH 6.3, 2.46 g of GAC for every 30 mL of graywater sample, 23.39 hrs contact time and $38.6^{\circ}C$.

반도체 제조공정 미세먼지-질소산화물 동시 저감을 위한 오존 고속산화공정 최적화 연구 (Optimization of an Ozone-based Advanced Oxidation Process for the Simultaneous Removal of Particulate Matters and Nitrogen Oxides in a Semiconductor Fabrication Process)

  • 엄성현;이승준;고은하;홍기훈;황상연
    • 공업화학
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    • 제32권6호
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    • pp.659-663
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    • 2021
  • 반도체 제조공정에서 발생하는 미세먼지와 질소산화물 동시처리를 위하여 오존산화, 습식중화 및 습식전기집진 기술들을 직접화한 10 CMM급 복합오염물질 제거시스템을 개발하였으며, NOx 제거효율 증대를 위한 공정변수 제어 및 최적화를 진행하였다. 특히, 전원공급장치를 포함한 습식전기집진장치 핵심부품 안정성 평가를 위해 30일 동안의 장기운전도 병행하였다. 오존산화 기반 DeNOx 공정에서 가장 중요한 운전변수인 O3/NO 비율은 1.5 부근에서 최적화하였으며, 습식중화 공정의 운전변수를 최적화하여 중화반응에 의한 제거효율 기여도를 확인하였다.