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http://dx.doi.org/10.3795/KSME-B.2010.34.10.893

Atherogenic Risk Stratification According to Changes in the Geometrical Shape of the Coronary Artery  

Suh, Sang-Ho (Dept. of Mechanical Engineering, Soongsil Univ.)
Park, Jun-Gil (Dept. of Mechanical Engineering, Soongsil Univ.)
Roh, Hyung-Woon (IVAI GD3)
Lee, Byung-Kwon (Cardiology Division, Dept. of Internal Medicine Gangnam Severance Hospital, Yonsei Univ.)
Kwon, Hyuck-Moon (Cardiology Division, Dept. of Internal Medicine Gangnam Severance Hospital, Yonsei Univ.)
Publication Information
Transactions of the Korean Society of Mechanical Engineers B / v.34, no.10, 2010 , pp. 893-899 More about this Journal
Abstract
A previous study showed that hemodynamics is correlated with stenosis in the coronary artery. The flow characteristics and the distributions of the hemodynamic wall parameters in the coronary artery are investigated under physiological flow condition. The present study also aims to establish the mechanism of the generation of atherosclerosis by analyzing the hemodynamic variables in the coronary artery where atherosclerosis frequently occurs. The stenosis phenomena due to atherosclerosis are related to not only the biochemical reaction between blood and blood vessels but also the hemodynamic factors sush as flow separation and oscillatory wall shear stress. As the bifurcated angle increases, the size of the recirculation area that appears in the cross section increases and disturbed flow is observed in this area. We speculate that this area is the starting point of atherosclerosis in the coronary artery.
Keywords
Coronary Artery; Geometrical Shape Change; Oscillatory Shear Index(OSI); Time-averaged Wall Shear Stress; Hemodynamic Wall Parameter(HWP);
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By SCOPUS : 0
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