• Title/Summary/Keyword: Reaction parameter

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Atherogenic Risk Stratification According to Changes in the Geometrical Shape of the Coronary Artery (관상동맥의 기하학적 형상변화에 따른 동맥경화 위험도)

  • Suh, Sang-Ho;Park, Jun-Gil;Roh, Hyung-Woon;Lee, Byung-Kwon;Kwon, Hyuck-Moon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.10
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    • pp.893-899
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    • 2010
  • A previous study showed that hemodynamics is correlated with stenosis in the coronary artery. The flow characteristics and the distributions of the hemodynamic wall parameters in the coronary artery are investigated under physiological flow condition. The present study also aims to establish the mechanism of the generation of atherosclerosis by analyzing the hemodynamic variables in the coronary artery where atherosclerosis frequently occurs. The stenosis phenomena due to atherosclerosis are related to not only the biochemical reaction between blood and blood vessels but also the hemodynamic factors sush as flow separation and oscillatory wall shear stress. As the bifurcated angle increases, the size of the recirculation area that appears in the cross section increases and disturbed flow is observed in this area. We speculate that this area is the starting point of atherosclerosis in the coronary artery.

Genetic Variation of the Mitochondrial Cytochrome b Sequence in Korean Rana rugosa (Amphibia; Ranidae)

  • Hyun Ick Lee;Dong Eun Yang;Yu Ri Kim;Hyuk Lee;Jung Eun Lee;Suh Yung Yang;Hei Yung Lee
    • Animal cells and systems
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    • v.3 no.1
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    • pp.89-96
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    • 1999
  • Nucleotide sequences of a 501 base-pair (bp) fragment in the mitochondrial cytochrome b (cyt b) gene were analyzed for 12 populations of Rana rugosa from Korea and Japan using a polymerase chain reaction (PCR) and direct silver sequencing. Two genetically distinct groups (type-A and type-B) were found in Korea. Type-A was found throughout most of South Korea and type-B was restricted to the mid-southeastern regions (Samchok, Yongdok, Chongsong and Pohang). But in the Tonghae population, both types were found. The level of mitochondrial DNA (mtDNA) sequence differences ranged from 0% to .0.8% among six populations of type-A, and 0 to 1.0% among 4 populations of type-B. However, sequence differences between type-A and type-B ranged from 5.4% to 6.6%, Using Kimura's two-parameter distance, the level of genetic sequence divergence between type-A and type-B was 6.7%. The Japanese R. rugosa was clustered very far from the Korean R. rugosa with 14.7%. In the neighbor-joining and UPGMA tree, all Korean samples were grouped, but subdivided into two types in 99% of the bootstrap iteration.

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Racemic and enantiomeric effect of tartaric acid on the hydrophilicity of polysulfone membrane

  • Sharma, Nilay;Purkait, Mihir Kumar
    • Membrane and Water Treatment
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    • v.7 no.3
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    • pp.257-275
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    • 2016
  • The enantiomeric and racemic effects of tartaric acid (TA) on the properties of polysulfone (PSn) ultrafiltration membranes were studied in terms of morphology and hydrophilicity (HPCT) of membrane. Asymmetric membranes were prepared by direct blending of polyvinyl pyrrolidone (PVP) with D-TA and DL-TA in membrane casting solution. FTIR analysis was done for the confirmation of the reaction of PVP and TA in blended membranes and plain PSn membranes. Scanning electron microscope (SEM), field emission scanning electron microscope (FESEM) and atomic force microscopy (AFM) were used for analyzing the morphology and structure of the resulting membranes. The membranes were characterized in terms of pure water flux (PWF), hydraulic permeability and HPCT. PWF increased from $52L/m^2h$ to $79.9L/m^2h$ for plain and D-TA containing PSn membrane, respectively. Water contact angle also found to be decreased from $68^{\circ}$ to $55^{\circ}$. In Additionally, permeation and rejection behavior of prepared membranes was studied by bovine serum albumin (BSA) solution. A considerable increase in BSA flux (from $19.1L/m^2h$ for plain membrane to $32.1L/m^2h$ for D-TA containing membrane) was observed. FESEM images affirm that the pore size of the membranes decreases and the membrane permeability increases from 0.16 to 0.32 by the addition of D-TA in the membrane. D-TA increases the HPCT whereas; DL-TA decreases the HPCT of PSn membrane. PVP (average molecular weight of 40000 Da) with D-TA (1 wt%) gave best performance among all the membranes for each parameter.

Fast Neutron Dosimetry with Two Threshold Detectors in Criticality Accidents of Nuclear Reactors

  • Ro, Seung-Gy
    • Nuclear Engineering and Technology
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    • v.2 no.2
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    • pp.85-95
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    • 1970
  • An attempt has been made to do interpretation of the fast neutron dose with two threshold detectors incorporated with the Harwell criticality locket. This method is based on the assumption that the spectral distribution of fission neutrons in criticality accidents may be governed by one spectral parameter. The surface-absorbed dose for a unit fission neutron fluence seems to be insensitive to spectral shifts of the fission neutron spectrum. The average cross-sections for the activation detectors, however, are considerably changed with the neutron spectral shape, which may lead to a large error in calculating the dose from the reaction rate if one uses a fixed value for the average cross sections regardless of the neutron spectral distribution. Besides, the doses calculated from three representative formulae for fission neutron spectra have been compared : these formulae are Watt, Cranberg at al. and Maxwellian forms. The results obtained front the Maxwellian formula show a departure from the Watt and Cranberg's, both being similarly close.

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Effect of Biphenyl Dimethyl Dicarboxylate on Cytochrome $P_{450}$ 1A1 and 2B1 and ${CCl_4}-Induced$ Hepatotoxicity in Rat Liver (Biphenyl Dimethyl Dicarboxylate가 간내 Cytochrome $P_{450}$ 1A1과 2Bl 및 $CCl_4$ 유도 간독성에 미치는 영향)

  • 김순선;오현영;김학림;양지선;김동섭;신윤용;최기환
    • YAKHAK HOEJI
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    • v.43 no.6
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    • pp.827-833
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    • 1999
  • In this study, we have investigated the effect of Biphenyl Dimethyl Dicarboxylate (DDB), a synthetic analogue of Schizandrin C isolated from Schizandrae Fructus on cytochrome $P_450$ lAl and 2Bl, and the protective mechanism against $CCl_4-induced$ hepatotoxicity in rat liver. After DDB was administered into male rats for different periods of time (1~7 days) and with different doses (25, 50, 100 and 200 mg/kg), mRNA levels of CYPlAl were measured by polymearse chain reaction (PCR) and assayed the activities of CYPlAl specific ethoxyresorufin-O-dealkylase (EROD) and CYP2Bl specific benzyloxyresorufin-O-dealkylase (BROD). DDB treatment resulted in increase in CYP2Bl mRNA level and BROD activity, whereas there was no change in CYPlAl mRNA level and EROD activity. This effect of DDB was time-and dose-dependent and reached maximal level by 3 day and 200 mg/kg treatment. In addition, rats were pre-treated with DDB at doses of 25, 50 or 100 mg/kg daily for 4 days, 3-hr after final treatment on the 4th day, $CCl_4$ 0.3ml/kg was intraperitonially injected into the rats to examine the effect of DDB on $CCl_4-induced$ hepatic injury. Serum levels of ALT and AST were determined and histopathological examination was done in rat liver. Furthermore, we have measured hepatic microsomal malondialdehyde(MDA) level, a parameter of lipid peroxidation. Based on serum ALT level and lipid peroxidation, pretreatment of DDB, 50 mg/kg appeared the most protective effect against $CCl_4-induced$ heapatotoxity. These results indicate that DDB stimulates CYP2Bl mRNA level and BROD activity in time and dose dependent manner and suggest that protective effect of DDB on $CCl_4-induced$ hepatotoxicity may be mediated through free radical scavenging.

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Reliability and validity of pelvic mobility measurement using a cushion sensor in healthy adults

  • Jung, Seung-Hwa;Kim, Su-Kyeong;Lee, Ji-Hyun;Choi, Soo-Ih;Park, Dae-Sung
    • Physical Therapy Rehabilitation Science
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    • v.9 no.2
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    • pp.74-81
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    • 2020
  • Objective: To prevent low back pain, an objective evaluation tool to evaluate pelvic mobility and exercise to improve the flexibility of the lumbar region is needed. The purpose of this study was to compare the results of pelvic mobility measurements using the Wii Balance Board (WBB) and Sensbalance Therapy Cushion (STC), evaluate the usefulness of the STC as a tool for measuring pelvic mobility. Design: Cross-sectional study. Methods: Fifty healthy subjects participated in this study. The subjects performed pelvic mobility range, proprioception, reaction time and reach of the arm using the STC. The pelvic movement parameter was measured two times to determine the intra-rater reliability. To measure the correlation between lumbar muscle tension and pelvic mobility, Myovision was used to measure tension of L4, L5 level erector spinae muscle. Correlations between measured variables were checked to determine the validity of the pelvic mobility assessment tool. Results: STC showed high test-retest reliability in pelvic tilt measurement and reaching task [intraclass correlation coefficients (3,1)=0.804-0.915]. The relationship between WBB and STC showed a significant positive correlation with the pelvic tilt and reaching task (p<0.05). Posterior tilt and erector spinae activation (Lt. L5) showed a significant negative correlation (p<0.05). Left, right tilt and erector spinae activation (L5) showed a significant negative correlation (p<0.05). Conclusions: This study confirmed the advantages of the STC and found efficiency as an objective measuring device of pelvic mobility.

Ionic Equilibria of Pt(IV), Pd(II) and Rh(III) in Hydrochloric Acid Solution (염산용액(鹽酸溶液)에서 白金(IV), 팔라듐(II)과 로듐(III)의 이온평형(平衡))

  • Lee, Man-Seung;Lee, Jin-Young
    • Resources Recycling
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    • v.18 no.1
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    • pp.30-37
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    • 2009
  • Distribution diagram of Pt(IV), Pd(II), and Rh(III) in HCl solution was obtained as a function of HCl concentration from 0.001 to 10 M by considering complex formation reaction together with mass balance. When HCl concentration was higher than 0.1 M, most of Pt and Pd in HCl solution exist as $PtCl_6^{2-}$ and $PtCl_4^{2-}$. The concentration of HCl had a feat effect on the speciation of Rh(III). As HCl concentration increases from 0.1 to 10 M, the pedominant species changes from $PhCl_5^{2-}$ to $PhCl_6^{3-}$. Interaction parameters of $PtCl_6^{2-}$ and $PdCl_4^{2-}$ with hydrogen ion were evaluated from the solvent extraction data of Pt and Pd reported in the literature.

Spectroscopic Ellipsometry of Si/graded-$Si_{1-x}Ge_x$/Si Heterostructure Films Grown by Reduced Pressure Chemical Vapor Deposition

  • Seo, J.J.;Choi, S.S.;Yang, H.D.;Kim, J.Y.;Yang, J.W.;Han, T.H.;Cho, D.H.;Shim, K.H.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.190-191
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    • 2006
  • We have investigated optical properties of Si/graded-$Si_{1-x}Ge_x$/Si heterostructures grown by reduced pressure chemical vapor deposition. Compared to standard condition using Si(100) substrate and growth temperature of $650^{\circ}C$, Si(111) resulted in low growth rate and high Ge mole fraction. Also samples grown at higher temperatures exhibited increased growth rate and reduced Ge mole fraction. The features regarding both substrate temperature and crystal orientation, representing high incorporation of silicon supplied from gas stream played as a key parameter, illustrate that reaction control were prevailed in this process growth condition. Using secondary ion mass spectroscopy and spectroscopic ellipsometry, microscopic changes in atomic components could be analyzed for Si/graded-$Si_{1-x}Ge_x$/Si heterostructures.

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Performance evaluation of organic matter adsorption from actual graywater using GAC: OrbitrapTM MS and optimization

  • Ligaray, Mayzonee;Kim, Minjeong;Shim, Jaegyu;Park, Jongkwan;Cho, Kyung Hwa
    • Membrane and Water Treatment
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    • v.10 no.6
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    • pp.471-484
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    • 2019
  • The complex combination of organic contaminants in the wastewater made water treatment challenging; hence, organic matter in water bodies is usually measured in terms of organic carbon. Since it is important to identify the types of compounds when deciding suitable treatment methods, this study implemented a quantitative and qualitative analysis of the organic matter content in an actual graywater sample from Ulsan, Republic of Korea using mass spectroscopy (MS). The graywater was treated using adsorption to remove the organic contaminants. Using orbitrap MS, the organic matter content between an untreated graywater and the treated effluent were compared which yielded a significant formula count difference for the samples. It was revealed that CHON formula has the highest removal count. Isotherm studies found that the Freundlich equation was the best fit with a coefficient of determination ($R^2$) of 0.9705 indicating a heterogenous GAC surface with a multilayer characteristic. Kinetics experiments fit the pseudo-second order equation with an $R^2$ of 0.9998 implying that chemisorption is the rate-determining step between the organic compounds and GAC at rate constant of $52.53g/mg{\cdot}h$. At low temperatures, the reaction between GAC and organic compounds were found to be spontaneous and exothermic. The conditions for optimization were set to achieve a maximum DOC and TN removal which yielded removal percentages of 94.59% and 80.75% for the DOC and TN, respectively. The optimum parameter values are the following: pH 6.3, 2.46 g of GAC for every 30 mL of graywater sample, 23.39 hrs contact time and $38.6^{\circ}C$.

Optimization of an Ozone-based Advanced Oxidation Process for the Simultaneous Removal of Particulate Matters and Nitrogen Oxides in a Semiconductor Fabrication Process (반도체 제조공정 미세먼지-질소산화물 동시 저감을 위한 오존 고속산화공정 최적화 연구)

  • Uhm, Sunghyun;Lee, Seung Jun;Ko, Eun Ha;Hong, Gi Hoon;Hwang, Sangyeon
    • Applied Chemistry for Engineering
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    • v.32 no.6
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    • pp.659-663
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    • 2021
  • 10 m3/min (CMM) multi-pollutants abatement system was successfully developed by effectively integrating ozone oxidation, wet scrubbing, and wet electrostatic precipitation for the simultaneous removal of particulate matters (PMs) and NOx in a semiconductor fabrication process. The sophisticated control and optimization of operating parameters were conducted to maximize the destruction and removal efficiency of NOx. In particular, the stability test of a wet electrostatic precipitator was carried out in parallel for 30 days to validate the reliability of core parts including a power supply. An O3/NO ratio, which is the most important operating parameter, was optimized to be about 1.5 and the optimization of wet scrubbing with a reducing agent made it possible to analyze the contribution of neutralization reaction.