• Title/Summary/Keyword: ReT

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Lineage re-commitment of CD4CD8αα intraepithelial lymphocytes in the gut

  • Park, Yunji;Moon, Sook-Jin;Lee, Seung-Woo
    • BMB Reports
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    • v.49 no.1
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    • pp.11-17
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    • 2016
  • The gastrointestinal tract forms the largest surface in our body with constantly being exposed to various antigens, which provides unique microenvironment for the immune system in the intestine. Accordingly, the gut epithelium harbors the most T lymphocytes in the body as intraepithelial lymphocytes (IELs), which are phenotypically and functionally heterogeneous populations, distinct from the conventional mature T cells in the periphery. IELs arise either from pre-committed thymic precursors (natural IELs) or from conventional CD4 or CD8αβ T cells in response to peripheral antigens (induced IELs), both of which commonly express CD8α homodimers (CD8αα). Although lineage commitment to either conventional CD4 T helper (Th) or cytotoxic CD8αβ T cells as well as their respective co-receptor expression are mutually exclusive and irreversible process, CD4 T cells can be redirected to the CD8 IELs with high cytolytic activity upon migration to the gut epithelium. Recent reports show that master transcription factors for CD4 and CD8 T cells, ThPOK (Th-inducing BTB/POZ-Kruppel-like factor) and Runx3 (Runt related transcription factor 3), respectively, are the key regulators for re-programming of CD4 T cells to CD8 lineage in the intestinal epithelium. This review will focus on the unique differentiation process of IELs, particularly lineage re-commitment of CD4 IELs. [BMB Reports 2016; 49(1): 11-17]

Stress Corrosion Cracking Sensitivity of High-Strength 2xxx Series Aluminum Alloys in 3.5 % NaCl Solution (항공용 고강도 2xxx계 알루미늄 합금의 3.5 % 염수 환경에서의 응력부식균열 민감도)

  • Choi, Heesoo;Lee, Daeun;Ahn, Soojin;Lee, Cheoljoo;Kim, Sangshik
    • Korean Journal of Materials Research
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    • v.28 no.12
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    • pp.738-747
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    • 2018
  • For the aerospace structural application of high-strength 2xxx series aluminum alloys, stress corrosion cracking(SCC) behavior in aggressive environments needs to be well understood. In this study, the SCC sensitivities of 2024-T62, 2124-T851 and 2050-T84 alloys in a 3.5 % NaCl solution are measured using a constant load testing method without polarization and a slow strain rate test(SSRT) method at a strain rate of 10-6 /sec under a cathodic applied potential. When the specimens are exposed to a 3.5 % NaCl solution under a constant load for 10 days, the decrease in tensile ductility is negligible for 2124-T851 and 2050-T84 specimens, proving that T8 heat treatment is beneficial in improving the SCC resistance of 2xxx series aluminum alloys. The specimens are also susceptible to SCC in a hydrogen-generating environment at a slow strain rate of $10^{-6}/sec$ in a 3.5 % NaCl solution under a cathodic applied potential. Regardless of the test method, low impurity 2124-T851 and high Cu/Mg ratio 2050-T84 alloys are found to have relatively lower SCC sensitivity than 2024-T62. The SCC behavior of 2xxx series aluminum alloys in the 3.5 % NaCl solution is discussed based on fractographic and micrographic observations.

Convective Heat Transfer in a Channel with Isothermal Rectangular Beams (등온사각빔이 부착된 채널에서의 대류열전달)

  • Ree, J.S.;Kwon, S.S.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.7 no.1
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    • pp.63-72
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    • 1995
  • Convective heat transfer in a two-dimensional horizontal and vertical channel with isothermal rectangular beams attached to one adiabatic wall is investigated from the numerical solution of Navier-Stokes and energy equations. The solutions have been obtained for dimensionless beam spacings, S/L=1~4, aspect ratios of beam, H/B=0.25~4, Reynolds numbers, Re=50~1000 and Grashof numbers, $Gr=0{\sim}5{\times}10^4$. The total mean Nusselt number, Nu_T for horizontal and vertical channels shows same value at Gr=0. As Gr increases, Nu_T for horizontal channel increases, but Nu_T for vertical channel shows similar value at S/L=2, H/B=0.25, Re=100. The total mean Nusselt number for horizontal channel is higher than that for vertical channel. As H/B increases, $Nu_T$ for both channel decrease at $Gr=10^4$, Re=100.

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Design and Implementation of Digital Contents Service System using Re-Direction Technique (Re-Direction 기법을 활용한 전자원문 연계시스템 설계 및 구현)

  • Cho, Sung-Nam;Lee, Sang-Hwan;Lee, Sang-Gi;Hwang, Chong-Sun;Chung, Taik-Yeong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.05a
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    • pp.1389-1392
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    • 2004
  • 정보통신 및 인터넷의 급속한 발전으로 전자원문 서비스 등 웹 서비스가 활발하게 이루어지고 있으나, 기존 웹 서비스에 대한 연구는 웹 서비스를 차별화하기 위해 HTTP의 속도지연 문제해결이나 서비스 차별화 방안에 대해 이루어지고 있다. 그러나, 타 시스템의 웹 서비스와 연계시 해당 웹 문서에 대한 제어권 확보에 관한 연구는 미미하다. 따라서, 본 논문에서는 타 시스템의 웹 문서에 대해 제어권 확보를 위해 Re-Direction Agent를 활용하여 해외전자원문 연계시스템을 구현하고자 한다.

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A Study on the Magnetic Properties of Amorphous Fe-Co-RE-B (RE=Nd, Sm, Gd, Tb) Alloys (비정질 Fe-Co-Re-B(RE=Nd, Sm, Gd, Tb) 합금의 자기적 성질)

  • 김경섭;유성초;김창식;김종오
    • Journal of the Korean Magnetics Society
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    • v.1 no.2
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    • pp.55-59
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    • 1991
  • The temperature-dependent magnetization curves of amorphous Fe-Co-(Nd, Sm, Gd, Tb)-B alloys were measured using a vibrating sample magnetometer from 77 K up to 900 K. The spin wave stiffness constants and the range of the exchange interaction were calculated from the saturation magnetization values at 0 K. Curie temperatures and the Bloch coefficients estimated from the saturation magnetization curves. The low temperature dependence of magnetization is in good agreement with Bloch relation, $M_{s}(T)=M_{s}(O)(1-BT^{3/2}-CT^{5/2})$. The spin wave stiffness constant and the range of exchange interaction are decreased by substitution of heavy rare earth (Tb, Gd).

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Effect of Adjustable Antenna Substrate Thickness on Aperture-Coupled Microstrip Antenna

  • Somsongkul, T.;Lorpichian, A.;Janchitrapongvej, K.;Anantrasirichai, N.;Wakabayashi, T.
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1664-1667
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    • 2003
  • Aperture-coupled microstrip antenna is one type of microstrip antennas. This type of antenna has bandwidth wider than simple microstrip antenna. Herein, we use two substrates, that have the same dielectric constant 2.47 (PTFE-quartz) in which upper substrate is a rectangular patch. The microstrip patch is fed by a microstrip line which is printed on lower substrate, through an aperture or slot in the common ground plane of patch and microstrip feed. This antenna is analyzed by using Finite Difference Time Domain (FDTD) method the specific design frequency 10 GHz and match impedance is 50 ohms. The simulation results of its characteristics are input impedance, return loss, VSWR and radiation patterns respectively.

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Mumetal Growing Temperature Effect on the Exchange Coupling of Cu/mumetal/Al Oxide/Co/Cu Multilayers

  • Lee, Y.W.;Lee, T.H.;Kim, C.G.;Kim, C.O.;Yoon, T.S.;Lee, Y.H.
    • Journal of Magnetics
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    • v.7 no.1
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    • pp.14-17
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    • 2002
  • Magnetic multilayers of a ferromagnetic (FM)/insulator (I)/ferromagnetic (FM) structure have been studied to investigate magnetic exchange coupling between two FM layers. As the Mumetal $(Ni_{77}Fe_{14}Mo_{5}Cu_4$ wt%) growth temperature increases, the grain size and the surface roughness increase simultaneously. The smallest coupling field is obtained at $40^\circ{C}$ where the grain size is larger than that of the $20^\circ{C}$ sample. The exchange coupling field increases again at temperatures higher than $40^\circ{C}$ due to increase in the surface roughness of the Mumetal.

The Theoretical Analyses of the Soil Erosion and Conservation 1. The Soil Renewal and Erosion (토양의 침식과 보존에 관한 이론적 분석 1. 토양의 생성과 침식)

  • 장남기
    • Asian Journal of Turfgrass Science
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    • v.10 no.1
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    • pp.21-29
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    • 1996
  • The mathematical expression in the forest and grassland soils to express the general concepts involved in such terms "a soil erosion and soil renewal. " The net addition rate in the forest and grassland soils are represented by an equation of $(S_{rb}-S_{ra})-(S_{eb}-S_{ea})={\int}_a^bR(m, cl, re, b, t )dt-{\int}E(w, r, cl, re, ch, b, t)dt{\gtreqqless}0$ where $S_r$, is renewal soil, $S_e$ is soil erosion, and variable factors are m =parent material of soil, cl=climate, re=relief or topography, ch=soil characteristics, r=rain or water, w=wind, b=biota, and t = time.

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The Behavior of Retention Wall By 3-D Finite Element Method (3차원 유한요소해석에 의한 흙막이 벽체의 거동특성)

  • 이진구;장서만;전성곤;이종규
    • Proceedings of the Korean Geotechical Society Conference
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    • 2001.03a
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    • pp.347-354
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    • 2001
  • In this study, 3-D FEM analysis are carried out to investigate the effect of the corners and re-entrant corners which can't be analysed by 2-D analysis. The excavation shape is re-entrant type conditions. The wall displacement, earth pressure and effectiveness of the corner struts are investigated in the re-entrant case, The 3D analysis are peformed to evaluate the effect of various factors, such as re-entrant corner size, excavation depth, and presence of struts. The wall displacement and earth pressures are influenced the size of re-entrant corner. Therefore, the effect of re-entrant corner should be considered in the evaluation of the earth pressure and displacement of the corners. Finally, strut-support systems are not effective at the re-entrant corner.

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