• 제목/요약/키워드: Rapid product development

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3D Shape Reconstruction of Cross-sectional Images using Image Processing Technology and B-spline Approximation (영상 처리 기법과 B-spline 근사화를 이용한 단면영상의 3차원 재구성)

  • 임오강;이진식;김종구
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2001.10a
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    • pp.93-100
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    • 2001
  • The three dimensional(3D) reconstruction from two dimensional(2D) image data is using in many fields such as RPD(Rapid Product Development) and reverse engineering. In this paper, the main step of 3D reconstruction is comprised of two steps : image processing step and B-spline surface approximation step. In the image processing step, feature points of each cross-section are obtained by means of several image processing technologies. In the B-spline surface approximation step, using the data of feature points obtained in the image processing step, the control points of B-spline surface are obtained, which are used for IGES file of 3D CAD model.

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A Study on the Development Of Standard Management System for the Work Efficiency Improvement of the Auto Part Supplier (자동차 부품업체의 업무 효율성 향상을 위한 표준관리시스템 구축에 관한 연구)

  • Lee, Hee-Nahm;Park, Je-Won
    • Journal of the Korea Safety Management & Science
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    • v.12 no.4
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    • pp.223-228
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    • 2010
  • Recently, the various information according to the company management is originated in the change of the rapid company environment. And the necessity of the administration,that is systematic and efficient toward the various document of a form, is gradually increased. At the same time, the efficient management ability of the various standard document obtained the specialized quality authentication system including the ISO/TS16949, ISO14001, quality 5 star, and etc., it maintains occupies the very important part as to the company management. This research suggests the standard business process of the auto part supplier for the efficient management of the standard document. In addition, by building and managing the standard management system will be able to expect the more efficient document management and the product reliability insurance.

Biosensors (바이오센서)

  • 김의락
    • KSBB Journal
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    • v.15 no.5
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    • pp.423-427
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    • 2000
  • Intense research on biosensors has been performed in a number of different institution over the past 15 years, but relatively few commercial products have resultingly, the blood glucose sensor is a good example of a product which penetrated the market. However recently, the development of electrochemical and optical technologies has accelerated the turnover of the research as is illustrated by a rapid increase in the number of point-of-care diagnostic systems and analytical devices. Examples of such biosensors used in the fields of medical diagnostics, bioprocess control, and environmental monitoring are described, and summarized in an introduction to their characteristics, structures, and functions, given.

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Development of a Cemented Carbide-Welded Deburring Tool for Burr Removal in Drill Holes of AL6061 Workpieces (AL6061 소재의 홀 가공 시 버 제거를 위한 초경합금 접합 디버링 공구 개발)

  • Sa, Min-Woo;Lee, Jae-Won
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.5
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    • pp.1-7
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    • 2021
  • In recent years, automated process technology has allowed for the rapid manufacturing of metal parts. Maintaining high product quality is of vital importance during the production of these parts. Surface defects occurring after processing can compromise their assembly precision and performance. In this study, a deburring tool was developed that can remove burrs generated from drilling. Through the evaluation of processing, burrs were completely removed at entrance and exit surfaces. Therefore, this newly developed deburring tool shows better performance than deburring tools currently in use.

Preparation of Enantiomerically Pure Chiral builing block ((E)-4-(tributylstannanyl) but-3-en-2-ol) via lipase-mediated resolution

  • Lee, Tae-Ho;Ko, Hyo-Jin;Lee, Hye-Seung;Kim, Sang-Hee
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.179.1-179.1
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    • 2003
  • Chiral building blocks have the importance in the pharmaceutical and agrochemical industries as well as in the development of rapid and efficient syntheses of bioactive compounds and natural product. Vinylstannane contains two synthetically useful functional groups (vinylstannane and allylic alcohol). The vinylstannane functional group can be used in C-C bond formation under a variety of conditions and the allylic alcohol functional can be used in hydroxyl-directed epoxidations, cyclopropanations, and sigmatropic rearrangements. (omitted)

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Features of Innovation and Project Management

  • Liakhovych, Galyna;Guk, Olga;Mokhonko, Ganna;Vakun, Oksana;Lyakhovych, Ulyana
    • International Journal of Computer Science & Network Security
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    • v.22 no.10
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    • pp.364-368
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    • 2022
  • The main purpose of the article is to study the features of innovation and project management. The rapid growth of scientific and technological progress in our time is leading to such profound changes that a passive, slow response to the development of science and technology leads to a growing backlog. That is why the main direction of efficient production should be a constant striving to improve product quality, timely replacement of the assortment, minimization of inventories, and ensuring the flexibility and mobility of technological processes. Based on the results of the study, the main features of innovation and project management were characterized.

A design Elements and the Aesthetics element analysis of the design of the Creativity (창의적 디자인의 디자인 구성요소와 심미성요소 분석)

  • Hong, Jung-Pyo;Jeong, Su-Kyoung
    • Science of Emotion and Sensibility
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    • v.11 no.3
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    • pp.387-396
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    • 2008
  • The paradigm of a product taking a sudden turn of technical development is due to a change of the needs of diversified user, and this shows that users emphasizes on the value of the sensitivity than the standardized form and usableness of the product, and the value of such a sensitivity can relate to the needs of the product, and it can be filled up eventually by the rapid completion of the product. The creativity will be the most important ability in the future society, it is an added value to all the profession workers which people can use that to increase their competitiveness ability. It is recognized the value of the sensitivity represents the feels psychological aspect of the user and it would be the future design trend, by doing this, products designed would be different from the existing products in the market. I am going to show you that this can be used in the design concept derivation process, there is several core design elements in the product development process, these elements can not only represent the basic user needs but also the user inner unconscious needs, at the same time it keeps the aesthetic concern.

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The current status and future directions of Korean inland freshwater aquaculture (우리나라 내수면 양식업의 현황 및 발전방향에 관한 소고)

  • Lee, Jung-Sam;Kim, Dae-Young
    • The Journal of Fisheries Business Administration
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    • v.37 no.3 s.72
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    • pp.1-24
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    • 2006
  • In terms of the size of aquaculture farms and production volume, inland freshwater aquaculture is much smaller than marine aquaculture in Korea. However, freshwater aquaculture provides fish which is not produced in the sea. Freshwater aquaculture plays an important role in the efficient use of resources, development of local areas and economy vitalization in under - developed areas. freshwater aquaculture also helps ecosystem recovery by stocking farmed fry. As addressed above, inland freshwater aquaculture plays various roles and can not be ignored. However, freshwater aquaculture has been off the interest of fisheries authority. Considering a series of changes in the circumstances such as the government's disapproval of pen - raised aquaculture, higher standard for discharged water from aquaculture farms and a rapid increase in import of low price fish from other countries, it is difficult to expect the quantitative expansion of the freshwater aquaculture any more. Furthermore, freshwater aquaculture lost the trust of people because of the use of Malachite green, and the consumption of farmed product plummeted last year. Even though it would be difficult to expect the quantitative expansion, we could expect qualitative growth and let the inland freshwater aquaculture keep playing the own roles. In order to achieve competitive advantage and regain the trust by providing safer farmed product, the government's support and freshwater aquaculture industry's active and voluntary efforts are very important. This paper suggests several points for the future oriented inland freshwater aquaculture in Korea such as strategic intensive development of selected species, the technical improvement and its diffusion, increased cooperation among the government authority, industry and scientists.

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SELECTING NIR EQUIPMENT TO MEET THE STRATEGIC REQUIREMENTS OF A GLOBALIZED PHARMACEUTICAL COMPANY

  • Dowd, Chris;Horvath, Steve;Lonardi, Silvano;Salton, Neale;Scott, Chris;Viviani, Romeo
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.3113-3113
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    • 2001
  • Some two years ago our company undertook a project on manufacturing network rationalization to maximize competitiveness through continuous improvement in manufacturing efficiency. One key outcome was the recognition of the benefits that could be derived from timely application of new technology or novel use of existing technologies and even more importantly the need to develop company wide strategies to maximize the impact of such applications. As a direct result an exercise was undertaken to identify the ten most promising technologies from a list of literally hundreds seen as having the capability of making a rapid impact on the manufacturing initiative. One of the outcomes of this exercise was the identification of Near Infrared Spectroscopy as a pivotal technology for improving process understanding, performance, and control to deliver consistent product quality cost effectively with broad applicability across our product range. While NIR had been in use in targeted areas on some of our sites for some years our new challenge was to develop a strategy to extend NIRs application, initially over 17 manufacturing sites, while concurrently expanding the NIR skill base company wide to ensure that the return on initial investment could be further maximized as shared applications across the remaining sites as required. This presentation will provide an overview of how life cycle based user requirement specifications were developed covering: ㆍSpectrophotometers ㆍSample interfaces ㆍSoftware ㆍEquipment and Software qualification ㆍCalibration transfer ㆍ Ease of developing effective user interfaces and control for applications transferred to a production area ㆍUser training ㆍWorld wide support The presentation will also describe the process adopted for vendor selection to ensure maximum utilization of the existing company wide NIR skill base and its future development to expedite applications of the technology in development, quality control and production areas.

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Biodistribution of 99mTc Labeled Integrin Antagonist

  • Jang, Beom-Su;Park, Seung-Hee;Shin, In Soo;Maeng, Jin-Soo;Paik, Chang H.
    • Toxicological Research
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    • v.29 no.1
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    • pp.21-25
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    • 2013
  • The selective targeting of an integrin ${\alpha}_v{\beta}_3$ receptor using radioligands may enable the assessment of angiogenesis and integrin ${\alpha}_v{\beta}_3$ receptor status in tumors. The aim of this research was to label a peptidomimetic integrin ${\alpha}_v{\beta}_3$ antagonist (PIA) with $^{99m}Tc(CO)_3$ and to test its receptor targeting properties in nude mice bearing receptor-positive tumors. PIA was reacted with tris-succinimidyl aminotriacetate (TSAT) (20 mM) as a PIA per TSAT. The product, PIA-aminodiacetic acid (ADA), was radiolabeled with $[^{99m}Tc(CO)_3(H_2O)_3]^{+1}$, and purified sequentially on a Sep-Pak C-18 cartridge followed by a Sep-Pak QMA anion exchange cartridge. Using gradient C-18 reverse-phase HPLC, the radiochemical purity of $^{99m}Tc(CO)_3$-ADA-PIA (retention time, 10.5 min) was confirmed to be > 95%. Biodistribution analysis was performed in nude mice (n = 5 per time point) bearing receptor-positive M21 human melanoma xenografts. The mice were administered $^{99m}Tc(CO)_3$-ADA-PIA intravenously. The animals were euthanized at 0.33, 1, and 2 hr after injection for the biodistribution study. A separate group of mice were also co-injected with 200 ${\mu}g$ of PIA and euthanized at 1 hr to quantify tumor uptake. $^{99m}Tc(CO)_3$-ADA-PIA was stable in phosphate buffer for 21 hr, but at 3 and 6 hr, 7.9 and 11.5% of the radioactivity was lost as histidine, respectively. In tumor bearing mice, $^{99m}Tc(CO)_3$-ADA-PIA accumulated rapidly in a receptor-positive tumor with a peak uptake at 20 min, and rapid clearance from blood occurring primarily through the hepatobiliary system. At 20 min, the tumor-to-blood ratio was 1.8. At 1 hr, the tumor uptake was 0.47% injected dose (ID)/g, but decreased to 0.12% ID/g when co-injected with an excess amount of PIA, indicating that accumulation was receptor mediated. These results demonstrate successful $^{99m}TC$ labeling of a peptidomimetic integrin antagonist that accumulated in a tumor via receptor-specific binding. However, tumor uptake was very low because of low blood concentrations that likely resulted from rapid uptake of the agent into the hepatobiliary system. This study suggests that for $^{99m}Tc(CO)_3$-ADA-PIA to be useful as a tumor detection agent, it will be necessary to improve receptor binding affinity and increase the hydrophilicity of the product to minimize rapid hepatobiliary uptake.