바이오센서

Biosensors

  • 김의락 (계명대학교 기초과학부 화학과)
  • 발행 : 2000.10.01

초록

바이오센서의 구조와 기능 그리고 종류에 대해 소개하였다. 이 분야의 연구가 과거 15년간 각국에서 경쟁적으로 연 구하였으나 glucose sensor가 상품화되 었을 뿐 연구결과를 상 품화한 것은 극히 적은 수였다. 그러나 최근 몇 년간 특히 포켓용 i-STAT point-of-care system의 도입 그리고 surface plasmon resonance와 evanescent wave 측정 장치 의 출현으로 상품화된 바이오샌서의 수가 크게 증가하는 추세에 었다. 이들 중 의료임상과 생물공정 그리고 환경오염 측정용으로 응 용되고 있는 몇 가지 상품에 대하여 약술하였다.

Intense research on biosensors has been performed in a number of different institution over the past 15 years, but relatively few commercial products have resultingly, the blood glucose sensor is a good example of a product which penetrated the market. However recently, the development of electrochemical and optical technologies has accelerated the turnover of the research as is illustrated by a rapid increase in the number of point-of-care diagnostic systems and analytical devices. Examples of such biosensors used in the fields of medical diagnostics, bioprocess control, and environmental monitoring are described, and summarized in an introduction to their characteristics, structures, and functions, given.

키워드

참고문헌

  1. Frontiers in Biosensorics v.Ⅰ,Ⅱ Scheller, F. W.;Schubert, F.;Fedrowitz, J.
  2. Biosensors: an Introduction Eggis, Brian R.
  3. Trib. Lett. v.3 Adhesion-Related Failure Mechanisms in Micromechanical Devices Mastrangelo, C.H.
  4. Anal Chem. v.70 chemical sensors Janata J.;Josowicz M;Vanysek P;DeVaney DM.
  5. Encyclopedia of Environmental Analysis and Remediation Biosensor technology for environmental measurement In Rogers, KR;Meyers RA(ed.)
  6. Chemical Sensors and Biosensors of Medical and Biological Applications Ursula E;Keller, S.
  7. Biosensors Cass, A. E. G.
  8. Clin. Chem. v.39 Evaluation of a novel point of care system, the i-STAT portable clinical analyzer Erikson, K. A.;Wilding, P
  9. J. Immunol. Methods v.145 Kinetic analysis of monoclonal antibody-antigen interactions with new biosensor based analytical system Karlson, R;Michaelsson, A.;Mattsson, L.
  10. Biosensors '94 Abstract (3rd World Congress on Biosensors) Affinity sensing using ultracompact wave guiding films Fattinger, ch. Mangold;C. Heming;M. Danielzik, B;Otto, J.
  11. Biosens. Bioelectron. v.9 Rapid BOD measurement with the Medingen BOD module Szweda, R.;Renneberg, R.
  12. Nurs. Manage. v.24 Point-of care testing: improving day-stay services Thiebe, L.;Vinci, K.;Gardner, J.
  13. IEEE Trans. Biomed. Eng. v.38 Noninvasive transcutaneous approach to glucose monitoring Kayashina, S.;Ari, T.;Mikuchi, M.;Sato, N.
  14. Anal. Chem. v.67 no.23 Real-time detection and quantification of DNA hybridization by an optical biosensor Watts, H. J.;Yeung, D.;Parkes, H.
  15. Nucl. Acids Res. v.24 no.12 Characterization of antibody-binding RNAs selected from structurally constrained libraries Hamm, J.
  16. JAMA v.276 Lifetime benefits and costs of intensive therapy as practiced in the diabetes control and complication trial The Diabetes Control and Complications Trial Research Group
  17. N. Engl. J. Med. v.329 no.14 The effect of intensive treatment of diabetes on the development and progression of long-term complication in insulin-dependent diabetes mellitus The Diabetes Control and Complications Trial Research Group
  18. Clin. Chem. v.41 no.6 Performance of Glucometer Elite and Glucometer Encore at altitude Parker, D. R.;Hiar, C. E.