• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3500-3505
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• 2009

Sixteen moderate atopic dermatitis patients were treated with applying toner and cream using estern medical herbs[Estern medical complex(Radix Glycyrrhizae, Radix Angelicae Dahuricae, Rhizoma Ligustici Chuanxiong, Fructus ponciri Seu Aurantii Immaturus, Radix Rehmanniae Praeparata, Radix Puerariae, Rhizoma Corydalis), Cypress, Green tea, Radix Astragali, Red ginseng, Syrup ferment, Apple ferment filtrate] on the atopic area 2-3 times per day for 6 weeks. After 6 weeks of study, the result was a decrease in SCORAD index($26.9{\pm}11.8$ to $14.9{\pm}9.7$(p<0.05)), IgE($641.9{\pm}1294.6$ to $565.8{\pm}1076.8$), Eosinophil count($246.7{\pm}203.5$ to $203.3{\pm}130.7$(p<0.05)) and TEWL($16.7{\pm}5.1$ to $15.4{\pm}8.7$(p<0.05)). And skin hydration was increased($36.6{\pm}10.0$ to $44.0{\pm}10.3$(p<0.01)) maintaining skin pH level. The patient;s and physician's global assessment also improved. Therefore, estern medical herbs may play a role in treatment of atopic dermatitis.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.39 no.4
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• pp.397-404
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• 1994

This experiment was conducted to determine best harvesting time and observe paeoniflorin and some chemical component concentrations of 4-year-old paeonia radix in Euisung and Milyang varieties. Concentrations of paeoniflorin and some chemical components were investigated at 8 periods from Feb. to Oct. Yield of paeonia radix was investigated in Aug. 19, Sep. 18 and Oct. 17. Paeoniflorin and some chemical components were changed seriously at May as flowering time and stabilized after June. The lowest dry matter ratio was 23% and the maximum shrinkage ratio was 47% in May during all the growing stages. Especially, the difference of paeoniflorin concentrations between Euisung and Milyang was about 2%, and paeoniflorin concentrations in Milyang were higher than in Euisung variety during all the stages. Serious infection of disease in October, stem length, stem number per stock and healthful stem ratio in October were more reduced than in August. Yield of paeonia radix was not different from August to September, but that of October harvest was obviously reduced by root-decay-disease. Reasonable harvesting time in 4-year-old paeonia radix was late August to mid-September. When infected shoot rate by disease were severely high, early harvest was more stable in the yield and quality aspects.

• Natural Product Sciences
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• v.24 no.3
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• pp.164-170
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• 2018

Rapid geographical classification of Bupleuri Radix is important in quality control. In this study, near infrared spectroscopy (NIRS) combined with supervised pattern recognition was attempted to classify Bupleuri Radix according to geographical origins. Three supervised pattern recognitions methods, partial least square discriminant analysis (PLS-DA), quadratic discriminant analysis (QDA) and radial basis function support vector machine (RBF-SVM), were performed to establish the classification models. The QDA and RBF-SVM models were performed based on principal component analysis (PCA). The number of principal components (PCs) was optimized by cross-validation in the model. The results showed that the performance of the QDA model is the optimum among the three models. The optimized QDA model was obtained when 7 PCs were used; the classification rates of the QDA model in the training and test sets are 97.8% and 95.2% respectively. The overall results showed that NIRS combined with supervised pattern recognition could be applied to classify Bupleuri Radix according to geographical origin.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.2
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• pp.51-75
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• 2000

The result were as follows: 1. Apply the drug to the affected part can used every time of ulcer. 2. Apply the drug to the affected part is used cold drug on yang-syndrome, hot drug on yin-syndrome, regulate drug on ban yin and ban yang-syndrome. 3. Apply the drug to the affected part is used alcohol, water, allii radix(인), zingiberis rhizoma recens(姜), juice of chrysanthemi flos(菊花) and so forth. 4. Apply the drug to the affected part can't used hot drug on yang-syndrome, cold drug on yin-syndrome. 5. Apply the drug to the affected part is used to be very busy of YouYuiKimHoangSan(如意金黃散). 6. Apply the drug to the affected part is used to be very busy on the angelicae adhuricae radix(白芷) of disperse the edema and drain the pus, and on the arisaematis rhizoma(南星), rhei radix et rhizoma(大黃), olibanum(乳香), phellodendri cortex(黃柏), calomelas(輕粉), glycyrrhizae radix(甘草), angelicae gigantis radix(當歸), myrrha(沒藥) of clearing away heat, activating blood circulation and relieve pain. 7. Apply the drug to the affected part is clearing away heat, activating blood circulation 8. Apply the drug to the affected part is cold and hot. 9. Apply the drug to the affected part is pungent, bitter and sweet. 10. Apply the drug to the affected part is non-toxic. 11. Apply the drug to the affected part is used to be very busy on the chanel of liver, heart, spleen, lung, stomach.

• Herbal Formula Science
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• v.28 no.2
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• pp.211-242
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• 2020

Objectives : This report describes 142 prescriptions related to the use of Astragalus mainly blended from Dongeuibogam. Methods : The following conclusions were drawn through investigations on the pre-scriptions that use Astragalus as a key component. Results : Prescriptions that Radix Aconiti Lateralis Preparata was taken as a monarch drug are utilized for 31 therapeutic purposes, for example, cold disease, stool disease, child disease. In particular, 17.3% of prescriptions appear in the chapter of cold. Prescriptions that utilize Radix Aconiti Lateralis Preparata as the main component are used in the treatment of cold, diarrhea and child disease, Bi syndrome due to pathogenic wind, cold and damp and they are also used for treating 55 different types of disease. Radix Aconiti Lateralis Preparata is used in pathogenic factors such as wind, cold and dampness and used in pathology related to the kidney and spleen and stomach system. The dosage of Radix Aconiti Lateralis Preparata is 2pun(about 0.75g) to 5don(about 18.8g), however 1don(about 3.75g)~1don 5pun(about 5.63g) has been taken the most for clinical application. Conclusions : Gangbutang and Ijungtang are the most useful base prescriptions which use the Radix Aconiti Lateralis Preparata as the main ingredient.

• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.6
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• pp.760-767
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• 2014

This paper describes a high-radix crossbar switch design with low latency and power dissipation for Network-on-Chip (NoC) applications. The reduction in latency and power is achieved by employing a folded-clos topology, implementing the switch organized as three stages of low-radix switches connected in cascade. In addition, to facilitate the uniform placement of wires among the sub-switch stages, this paper proposes a Mux-Matrix-Mux structure, which implements the first and third switch stages as multiplexer-based crossbars and the second stage as a matrix-type crossbar. The proposed 256-radix, 8-bit crossbar switch designed in a 65nm CMOS has the simulated power dissipation of 1.92-W and worst-case propagation delay of 0.991-ns while operating at 1.2-V supply and 500-MHz frequency. Compared with the state-of-the-art designs in literature, the proposed crossbar switch achieves the best energy-delay-area efficiency of $0.73-fJ/cycle{\cdot}ns{\cdot}{\lambda}^2$.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.3A
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• pp.368-376
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• 2006

This paper describes a Fcore_GenSim(Parameterized FFT Core Generation & Simulation Program), which can be used as an essential If(Intellectual Property) in various OFDM modem designs. The Fcore_Gensim is composed of two parts, a parameterized core generator(PFFT_CoreGen) that generates Verilog-HDL models of FFT cores, and a fixed-point FFT simulator(FXP_FFTSim) which can be used to estimate the SQNR performance of the generated cores. The parameters that can be specified for core generation are FFT length in the range of 64 ~2048-point and word-lengths of input/output/internal/twiddle data in the range of 8-b "24-b with 2-b step. Total 43,659 FFT cores can be generated by Fcore_Gensim. In addition, CBFP(Convergent Block Floating Point) scaling can be optionally specified. To achieve an optimized hardware and SQNR performance of the generated core, a hybrid structure of R2SDF and R2SDC stages and a hybrid algorithm of radix-2, radix-2/4, radix-2/4/8 are adopted according to FFT length and CBFP scaling.

• Korean Journal of Food Science and Technology
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• v.40 no.2
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• pp.135-140
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• 2008

In this study, the macromineral content ratios of four herbal medicine samples(Saposhnikoviae Radix, Bupleuri Radix, Cnidii Rhizoma, and Astragali Radix) were analyzed to discriminate their geographical origins using an energydispersive x-ray fluorescence (EDXRF) technique. EDXRF is a rapid, non-destructive, and multi-elemental analysis technique. Initially, samples of both domestic and imported herbal medicines were pulverized, and then their macromineral contents, including P, S, K, and Ca, were analyzed using EDXRF. For the discrimination of their geographical origins, canonical discriminant analysis was carried out based on the estimated macromineral relative content ratios of the samples. According to the results, the discrimination accuracies were as follows: 93.3% for Saposhnikoviae Radix, 95.7% for Bupleuri Radix, 98.8% for Cnidii Rhizoma, and 87.5% for Astragali Radix. Overall, the results imply that this technique could be used as a standard method, to discriminate their geographical origins between domestic and imported herbal medicines.

• Korean Journal of Medicinal Crop Science
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• v.21 no.6
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• pp.486-492
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• 2013

This study has been conducted to establish the optimal extraction process and HPLC analysis method for the determination of marker compounds as a part of the materials standardization for the development of health functional food materials from Astragali radix. Five extraction conditions including the shaking extraction at room temperature and the reflux extraction at $85^{\circ}C$ with 30%, 50% and 95% ethanol were evaluated. Reflux extraction with 50% ethanol showed the highest extraction yield as $27.27{\pm}2.27%$, while the extraction under reflux with 95% ethanol showed significantly the lowest yield of $10.55{\pm}0.24%$. The quantitative determination methods of calycosin-7-O-${\beta}$-D-glucoside and calycosin as marker compounds of Astragali radix extracts were optimized by HPLC analysis using a Thermo Hypersil column ($4.6{\times}250mm$, $5{\mu}m$) with the gradient elution of water and acetonitrile as the mobile phase at the flow rate of $0.8mLmin^{-1}$ and a detection wavelength of 230nm. The HPLC/UV method was applied successfully to the quantification of two marker compounds in Astragali radix extracts after validation of the method with the linearity, accuracy and precision. The contents of calycosin-7-O-${\beta}$-D-glucoside and calycosin in 50% ethanol extracts by reflux extraction were significantly higher as $1,700.3{\pm}30.4$ and $443.6{\pm}8.4{\mu}g-1$, respectively, comparing with those in other extracts. The results indicate that the reflux extraction with 50% ethanol at $85^{\circ}C$ is optimal for the extraction of Astragali radix, and the established HPLC method are very useful for the evaluation of marker compounds in Astragali radix extracts to develop the health functional material from Astragali radix.

• Journal of Acupuncture Research
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• v.29 no.3
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• pp.9-18
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• 2012

Objectives : This research was performed to investigate the effects of Rhei Radix et Rhizoma pharmacopuncture at Bi-Su($BL_{20}$) on weight change, food efficiency, concentration of serum lipid, liver function of rats fed high fat diet for 8 weeks. Methods : Subject groups were diveded into normal diet group(Normal), high fat diet group(Control), high fat diet and saline in $BL_{20}$ treated group(Saline), high fat diet and Rhei Radix et Rhizoma pharmacopuncture in $BL_{20}$ treated group(PT-1, 0.008mg/ml/g), high fat diet and Rhei Radix et Rhizoma pharmacopuncture in $BL_{20}$ treated group(PT-2, 0.021mg/ml/g), and high fat diet and Rhei Radix et Rhizoma pharmacopuncture in $BL_{20}$ treated group(PT-3, 0.042mg/ml/g). Pharmacopuncture was bilaterally treated at BL20 every 4 days, totally 14 times in 56 days. We observed the changes of body weight, food efficiency, ALT, AST, r-GTP, total cholesterol, triglyceride, HDL, LDL-cholesterol of each group. Results : 1. Body weight significantly decreased, as compared with the control group, in PT-1 from 2nd week to 8th week, in PT-2 from 4th week to 7th week. 2. Food efficiency decreased, as compared with the control group, in PT-1(0.05${\leq}$p<0.06). 3. HDL-cholesterol increased, as compared with the control group, in PT-1, PT-3, but not significantly. 4. In the changes of ALT, as compared with the control group, only in PT-1 group, the level of serum ALT decreased(0.05${\leq}$p<0.06). 5. As for the changes of r-GTP, as compared with control group, in every subject group, the levels of serum r-GTP significantly decreased. Conclusions : According to the above results, Rhei Radix et Rhizoma pharmacopuncture at $BL_{20}$ can act on body weight, food efficiency and liver function. It also does not seem to be injurious on liver function. To use Rhei Radix et Rhizoma pharmacopuncture for obesity, further studies on its underlying mechanism and optimal dosage might be needed.