Evaluation on Extraction Conditions and HPLC Analysis Method for Bioactive Compounds of Astragali Radix |
Kim, Geum Soog
(Department of Herbal Crop Research, NIHHS, RDA)
Lee, Dae Young (Department of Herbal Crop Research, NIHHS, RDA) Lee, Seung Eun (Department of Herbal Crop Research, NIHHS, RDA) Noh, Hyung Jun (Department of Herbal Crop Research, NIHHS, RDA) Choi, Je Hun (Department of Herbal Crop Research, NIHHS, RDA) Park, Chun Geun (Department of Herbal Crop Research, NIHHS, RDA) Choi, Soo Im (YD Life Science Research Institutes, YD Life Science Co. Ltd.) Hong, Seung Jae (Kyung Hee University Medical Center) Kim, Seung Yu (Department of Herbal Crop Research, NIHHS, RDA) |
1 | Cho WCS and Leung KN. (2007). In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Letters. 252:43-54. DOI ScienceOn |
2 | Choi S, Park SR and Heo TR. (2005). Inhibitory effect of Astragali radix on matrix degradation in human articular cartilage. Journal of Microbiology and Biotechnology. 15:1258-1266. |
3 | Choi SI, Heo TR, Min BH, Cui JH, Choi BH and Park SR. (2007). Alleviation of osteoarthritis by calycosin-7-O--Dglucopyranoside( CG) isolated from Astragali radix(AR) in rabbit osteoarthritis(OA) model. Osteoarthritis and Cartilage. 15:1086-1092. DOI ScienceOn |
4 | Dong TTX, Ma XQ, Clarke C, Song ZH, Ji ZN, Lo CK and Tsim KWK. (2003). Phylogeny of Astragalus in China: Molecular evidence from the DNA sequences of 5S rRNA spacer, ITS, and 18S rRNA. Journal of Agricultural and Food Chemistry. 51:6709-6714. DOI ScienceOn |
5 | Du XG, Zhao B, Li JY, Cao XH, Diao MK, Feng HB, Chen XB, Chen ZY and Zeng XY. (2012). Astragalus polysaccharides enhance immune responses of HBV DNA vaccination via promoting the dendritic cell maturation and suppressing Treg frequency in mice. International Immunopharmacology. 14:463-470. DOI ScienceOn |
6 | Kajimura K, Takagi Y, Ueba N, Yamasaki K, Sakagami Y, Yokoyama H and Yoneda K. (1996). Protective effect of Astragali radix by intraperitoneal injection against Japanese encephalitis virus infection in mice. Biological & Pharmaceutical Bulletin. 19:855-859. DOI ScienceOn |
7 | Kim JH, Park SY, Lim HK, Park AY, Kim JS, Kang SS, Youm JR and Han SB. (2007). Quantitative evaluation of Astragali radix through the simultaneous determination of bioactive isoflavonoids and saponins by HPLC/UV and LCESI-MS/MS. Bulletin of the Korean Chemical Society. 28:1187-1194. 과학기술학회마을 DOI ScienceOn |
8 | Kim JS and Kim CS. (1997). A study on the constituents from the roots of Astragalus membranaceus Bunge (II). Korean Journal of Pharmacognosy. 28:75-79. 과학기술학회마을 |
9 | Kim JS, Kim YT and Kim CS. (2002). A study on the constituents from the roots of Astragalus membranaceus Bunge (III). Korean Journal of Pharmacognosy. 31:109-111. 과학기술학회마을 |
10 | Kim SH, Jun YM, Lim JJ, Kim SH, Chung IM and Kim EH. (2012). Variation of astragalosides contents in cultivated Astragalus membranaceus. Korean Journal of Medicinal Crop Science. 20:372-380. 과학기술학회마을 DOI ScienceOn |
11 | Kim SP, Kim SM, Ryu HS, Shin JC, Lee DG, Lee OJ, Lee JH and Kim JH. (2012a). The effects of Astraglai radix pharmacopuncture at CV12 on osteoporosis of senescence accelerated mice(SAM) P6. The Journal of Korean Acupuncture & Moxibustion Medicine Society. 29:59-71. |
12 | Lee DY, Noh HJ, Choi J, Lee KH, Lee MH, Lee JH, Hong Y, Lee SE, Kim SY and Kim GS. (2013). Anti-Inflammatory cycloartane-type saponins of Astragalus membranaceus. Molecules. 18:3725-3732. DOI ScienceOn |
13 | Lee YM, Choi SI, Lee JW, Jung SM, Park SM and Heo TR. (2005). Isolation of hyaluronidase inhibitory component from the roots of Astraglus membranaceus Bunge(Astragali radix). Food Science and Biotechnology. 14:263-267. 과학기술학회마을 |
14 | Lv YW, Hu W, Wang YL, Huang LF, He YB and Xie XZ. (2011). Identification and determination of flavonoids in Astragali radix by high performance liquid chromatography coupled with DAD and ESI-MS detection. Molecules. 16:2293-2303. DOI ScienceOn |
15 | Lee YS, Han OK, Park CW, Suh SI, Shin SW, Yang CH, Jeon TW, Lee ES, Kim KJ, Kim SH, Yoo WK and Kim HJ. (2003). Immunomodulatory effects of aqueous-extracted Astragali radix in methotrexate-treated mouse spleen cells. Journal of Ethnopharmacology. 84:193-198. DOI ScienceOn |
16 | Lei H, Wang B, Li WP, Yang Y, Zhou AW and Chen MZ. (2003). Anti-aging effect of astragalosides and its mechanism of action. Acta Pharmacologica Sinica. 24:230-234. |
17 | Liu J, Zhao ZZ and Chen HB. (2011). Review of Astragali radix. Chinese Herbal Medicines. 3:90-105. |
18 | Ministry of Agriculture, Food and Rural Affairs(MAFRA). (2013). Production report of industrial crops in 2012. Ministry of Agriculture, Food and Rural Affairs. Sejong, Korea. p.85. |
19 | Ministry of Food and Drug Safety(MFDS). (2013). The Korean pharmacopoeia. Ministry of Food and Drug Safety. Osong, Korea. p.1228. |
20 | Ministry of Food and Drug Safety(MFDS). (2013). The functional ingredients recognized status of health functional food. Ministry of Food and Drug Safety. Osong, Korea. p.5. |
21 | Wang XJ and Feng P. (2000). Antioxidant activity of Qizhu tang. Acta Pharmacologica Sinica. 21:1141-1144. |
22 | Zhang WJ, Hufnagl P, Binder BR and Wojta J. (2003). Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappa B activation and adhesion molecule expression. Thrombosis and Haemostasis. 90:904-914. |
23 | Zhang YD, Wang YL and Shen JP. (1984). Effect of astragaloside IV on inflammatory and hypertension. Acta Pharmacologica Sinica. 19:333-337. |