• Journal of Radiopharmaceuticals and Molecular Probes
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• v.2 no.2
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• pp.132-136
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• 2016

Radiolysis is the process of decreasing in Radio-Chemical Purity (RCP) of [$^{18}F$]FDG by direct effect and indirect effect of self Radio-activity. The objective of our study was to figure out the ideal conditions which minimize damages of quality of [$^{18}F$]FDG using radical scavenger and controlling temperature of storage.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2003.11a
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• pp.369-386
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• 2003

Radiation technologies are being utilized in a wide range of daily modern life and provide the public with valuable benefits through applications in fields of medical, industrial, agricultural, and science & engineering research. On the other hand, there is a high possibility that radioactive materials can be used for malevolent purposes such as dirty bombs. The International community, therefore, has made efforts to improve the security of radioactive sources aimed at protecting the public from radiological terrorism. The paper investigated high-risk radioactive sources which could be used as dirty bombs. The paper reviewed the possibility of radiological weapon attacks and analyzed international trends to enhance security of radioactive sources. This study also proposed our countermeasures to reduce the threat of radiological terrorism and to properly respond to the radiological emergency caused by the radiological weapon attack.

• Nuclear Engineering and Technology
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• v.37 no.2
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• pp.185-190
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• 2005

The Korea Institute of Radiological and Medical Sciences (KIRAMS) electron microbeam system has been built with its prototype components. The system is composed of an electron gun, a beam transport chamber, and a cell image acquisition and positioning stage. Each component has been upgraded through repetitive performance tests for various parametric arrangements. This paper presents the preliminary results of the performance test on the beam control and detection parts of the system.

• Journal of radiological science and technology
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• v.20 no.2
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• pp.28-33
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• 1997

For the Evaluation of X-ray image intensifier, we measured radiation dose at input of I. I., brightness and fluorescence at output of I. I. by using X-ray exposure meter, optometer and fluorescence meter for the relative conversion factor. Especially, by using fluorescence meter, we could easily get relative conversion factor without having regulated machine by JIS. Since using, the quality of image intensifier is going down. Consequently, it needs continuous quality maintenance.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.813-815
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• 2005

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.206.1-206.1
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• 2003

The immunomodulator Ginsan has been found previously by us to stimulate the secretion of high levels of IL -1. IL -6 and TNF-alpha in irradiated mice. These cytokines are known to induce proliferation and differentiation of hematopoietic progenitor cells from the spleen and bone marrow and to protect mice from DNA-damaging agents. The present studies were evaluated as a cytoprotective agent against toxicity of the alkylating drugs. (omitted)

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.1
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• pp.17-23
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• 2022

Boron neutron capture therapy is a precision treatment technology that selectively destroys only tumor cells by irradiating thermal neutrons after accumulating boron drugs in tumor cells. Brain tumor is difficult to diagnose and treat due to the low permeability and targeting of drugs caused by the blood-brain-barrier. Crossing the BBB is essential for drug delivery to the brain. In this study, we designed and synthesized a novel compound incorporating benzothiazole to develop a boron drug with high BBB permeability and selectivity for brain tumor cells. In addition, their potential as a BNCT drugs was evaluated.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.7 no.1
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• pp.3-10
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• 2021

For successful boron neutron caputre therapy, it is essential to develop a boron drug with a selective accumulation capacity for tumors. In particular, in order to apply boron neutron caputre therapy to brain tumors, drugs with good blood-brain barrier penetration are required. In this study, two low-molecular-weight boron compounds were introduced as brain tumor boron neutron caputre therapy drugs, and their physical and biological efficacy were evaluated. Among them, B2 showed good blood-brain barrier permeability and a high brain/blood ratio. From these results, it is expected that B2 can be used as a useful boron drug for boron neutron caputre therapy in brain tumors.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.1064-1065
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• 2005

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.797-797
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• 2005