• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6161-6164
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• 2014

Background: We have reported the radiation could activate STAT3, which subsequently promotes the invasion of A549 cells. We here explored the dose- and time-response of STAT3 to radiation and the effect of radiation on upstream signaling molecules. Materials and Methods: A549 cells were irradiated with different doses of ${\gamma}$-rays. The expression of and nucleus translocation of p-STAT3 in A549 cells were detected by immunoblotting and immunofluorescence, respectively. The level of phosphorylated EGFR was also assessed by immunoblotting, and IL-6 expression was detected by real time PCR and ELISA. Results: Radiation promoted the phosphorylation of STAT3 at Y705 in a dose- and time-dependent manner and nuclear translocation. The level of phosphorylated EGFR in A549 cells increased after radiation. In additional, the mRNA and protein levels of IL-6 in A549 cells were also up regulated by radiation. Conclusions: STAT3 is activated by radiation in a dose-and time-dependent manner, probably due to radiation-induced activation of EGFR or secretion of IL-6 in A549 cells.

• Journal of Korea Entertainment Industry Association
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• v.14 no.7
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• pp.571-579
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• 2020

This study was attempted to identify the analysis of educational needs and correlation between knowledge and attitude of radiation protection among emergency medical services students for life care to recognize the importance of radiation protection and provide the basic data for developing personalized educational programs for safety management in radiation protection for emergency medical services students. The result showed that the correlation between knowledge about radiation protection and attitude toward it, there was a positive correlation between attitude score and knowledge score regarding the radiation protection (r=.472, p<.000). In participation intention into the education about the radiation protection, 82% of the responders said that they had participation intention. In time when they are to be educated, 2nd graders was the highest at 54.9%, in instructional method, lecture with audiovisual materials was the highest at 59.04%, and in lecturer, radiological technologist was the highest at 77.45%. It could be found from such findings that emergency medical services students' life care of education needs for radiation protection and participation intention were high and concluded that safety management educational program development for radiation protection is required with accurate knowledge about radiation protection and positive attitude and to increase the educational effects, radiological technologist's utilizing the audiovisual materials for instruction is the most effective.

• Journal of Korean Clinical Health Science
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• v.2 no.2
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• pp.133-147
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• 2014

Purpose. Radiation therapy for oncologic emergencies is an important modality in the management of cancer patients. The aim of the present study was to review the roles of RT in oncologic emergencies based on literature review. Methods. The oncologic emergencies requiring rapid treatment include superior vena cava syndrome, spinal cord compression, brain metastasis, and bone metastasis. We reviewed the literatures on the pathophysiology, diagnosis, and treatment of oncologic emergencies. Results. In this literature review, radiation therapy among treatment modalities for oncologic emergencies has been shown to be fast and very effective treatment modality for oncologic emergencies. Conclusions. Based on this review, we conclude that the literature provides support for the role of radiation therapy in the situation of oncologic emergencies. As the number of cancer patients increase, the prevalence of oncologic emergencies will increase. In the future, the development of RT techniques will provide the improvement of not only patient's quality of life but also the survival.

• Journal of Radiation Protection and Research
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• v.39 no.2
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• pp.96-102
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• 2014

Urine bioassay has been widely used for internal dosimetry due to simple process of sampling and measurement. In this paper, we participated in the NRIP (NIST Radiochemistry Intercomparison Program) hosted by US NIST to carry out a reliable performance test of urine bioassay and introduced the measurement method and results of NRIP-2013. In customary exercise with 60 days of reporting time, bioassay results of 12 radionuclides in the synthetic urine samples were acceptable based on the performance criteria of ANSI N13.30. In emergency preparedness exercise with 8 hours of reporting time, bioassay results of 9 radionuclides showed that differences ranged from -35% to 45%. However, we concluded that urine bioassay applied for emergency preparedness exercise would be applicable for rapid screening and estimation of internal exposure within a difference of ${\pm}45%$ in the event of radiological accidents.

• Journal of Aerospace System Engineering
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• v.17 no.1
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• pp.68-78
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• 2023

In this paper, improvement measures were studied for false alarm (abnormal lighting) of emergency hydraulic warning light due to RF radiation signals in aircraft. When the warning lamp of the emergency hydraulic system is lit during flight due to electromagnetic interference caused by RF radiation signals, it affects flight mission and safety which can result in efficiency degradation and maintenance of flight mission. For false alarm of emergency hydraulic warning light, root cause analysis and troubleshooting were carried out. By shielding a composite strip under fuselage of the aircraft located in the path of the RF radiation signal, the RF radiation signal flowing into the emergency hydraulic indicator was blocked. Results of applying the improvement method through ground and flight monitoring were also described.

• Journal of Radiation Protection and Research
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• v.46 no.2
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• pp.66-79
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• 2021

Background: The Japan Atomic Energy Agency (JAEA) is specified in the Disaster Counter-measures Basic Act as a designated public corporation for dealing with nuclear disasters. Materials and Methods: The Nuclear Emergency Assistance and Training Center (NEAT) was established in 2002 as the activity base providing technical assistance to both national and local governments during nuclear emergencies. The NEAT has a robust structure and utilities and special installations, and it organizes training and exercises. Results and Discussion: Due to an offshore earthquake that caused a devastating tsunami in March 2011, a nuclear accident occurred at the Tokyo Electric Power Company's Fukushima Daiichi Nuclear Power Station. The NEAT responded by conducting off-site environmental radiation monitoring and contamination screening, dispatching special vehicles, offering telephone consultations, and calculating the dispersion of radioactive materials. An examination of the emergency response activities revealed that the organization was prepared for these types of disasters and was able to plan long-term response. Conclusion: As a designated public corporation, the JAEA technically supports the national government, the Fukushima prefectural government, and the Ibaraki prefectural government, all of which responded to the off-site emergencies resulting from the March 2011 Fukushima Daiichi accident

• Nuclear Engineering and Technology
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• v.52 no.10
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• pp.2379-2386
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• 2020

This paper presents the results of the first intercomparison exercise performed by the Korea retrospective dosimetry (KREDOS) working group using electron paramagnetic resonance (EPR) spectroscopy. The intercomparison employed the alanine dosimeter, which is commonly used as the standard dosimeter in EPR methods. Four laboratories participated in the dose assessment of blind samples, and one laboratory carried out irradiation of blind samples. Two types of alanine dosimeters (Bruker and Magnettech) with different geometries were used. Both dosimeters were blindly irradiated at three dose levels (0.60, 2.70, and 8.00 Gy) and four samples per dose were distributed to the participating laboratories. Assessments of blind doses by the laboratories were performed using their own measurement protocols. One laboratory did not participate in the measurements of Magnettech alanine dosimeter samples. Intercomparison results were analyzed by calculating the relative bias, E_n value, and z-score. The results reported by participating laboratories were overall satisfactory for doses of 2.70 and 8.00 Gy but were considerably overestimated with a relative bias range of 10-95% for 0.60 Gy, which is lower than the minimum detectable dose (MDD) of the alanine dosimeter. After the first intercomparison, participating laboratories are working to improve their alanine-EPR dosimetry systems through continuous meetings and are preparing a second intercomparison exercise for other materials.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.2
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• pp.300-305
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• 2017

In this paper, we performed a evaluation for angular and energy dependence of military radiation detector PDR-1K. Its measuring range is divided into two section, low and high, and each range has a GM tube separately owing to broad scale. We observed a change in relative angular reactivity within 0.928 ~ 1.188 in low range and within 0.743 ~ 1.000 in high range from $-90^{\circ}$ to $+90^{\circ}$. The evaluation for energy dependence appeared a relative reactivity within 0.892 ~ 1.000 above 83 keV. This means PDR-1K isn't possible to use below 83 keV of radiation energy. It is possible to provide response information to user and to increase reliability of radiation measurement through this paper.

• Journal of Magnetics
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• v.17 no.3
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• pp.172-175
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• 2012

We present a method for detecting very weak radiation by analyzing the inner structure of irradiated tris (lyoluminescence) materials using electron paramagnetic resonance (EPR) at low temperature. Organic materials have been looked into for use in emergency dosimetry of inhabitants around radiation accidents. However, this technology has never been applied to imperceptible radiation doses (< 0.5 Gy) because there is no proper method for detecting the change of inner structure of the subject bombed by very weak radiation at room temperature. Our results show that tris materials can be applied as a radiation detectors of very small radiation doses below 0.05 Gray, if EPR is used at low temperature (130 K ${\leq}$ T ${\leq}$ 270 K). The EPR signal intensity from the irradiated-tris sample had barely faded at all after 1 year.

• Journal of Radiation Protection and Research
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• v.38 no.2
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• pp.52-59
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• 2013

The internal contamination screening method using gross beta measurement was performed for radioisotope workers. 24 h and spot urine samples from workers of medical isotope production facilities were collected and measured. Most of the results were similar with the background level of gross beta activity except for a specific worker. Gross beta activity was slightly increased in several hours after finishing work. And the environmental factor of production facilities causing internal contamination were estimated based on screening results. The additional detailed internal dose assessment must be followed after the screening for protection of workers. Moreover, a procedure was established to apply a simple internal contamination assessment for radiation workers.