• Clinical and Experimental Reproductive Medicine
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• v.47 no.1
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• pp.68-76
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• 2020

Objective: Since sperm abnormalities are known to be a major reason for recurrent pregnancy loss (RPL), any defects in DNA structure and chromatin condensation can place embryos at risk in the early stage of development and implantation. As antioxidants such as vitamin C may play a protective role against the destruction of protamine genes in sperm chromatin, this study was conducted to evaluate the effects of vitamin C on chromatin and the expression of protamine genes in the male partners of couples with RPL. Methods: Twenty male partners of couples with RPL were selected as the intervention group and received vitamin C supplementation (250 mg daily for 3 months). Healthy fertile men (n = 20) were included as controls. Sperm chromatin, DNA integrity, and the expression levels of protamine genes were evaluated before and after treatment. Results: Significant differences were found in sperm morphology, protamine deficiency, and apoptosis between the two groups and before and after vitamin C administration. A significant change was found in mRNA levels of PRM1, PRM2, and the PRM1/PRM2 ratio after treatment. Conclusion: Daily oral administration of vitamin C may improve human sperm parameters and DNA integrity by increasing protamine gene expression levels in the male partners of couples with RPL. The beneficial effects of vitamin C supplementation as an antioxidant for the male partners of couples with RPL could lead to improved pregnancy outcomes in these cases.

• Journal of Communications and Networks
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• v.18 no.3
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• pp.327-332
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• 2016

The routing protocol for low-power and lossy networks (RPL) is an internet protocol based routing protocol developed and standardized by IETF in 2012 to support a wide range of applications for low-power and lossy-networks (LLNs). In LLNs consisting of resource-constrained devices, the energy consumption of battery powered sensing devices during network operations can greatly impact network lifetime. In the case of inefficient route selection, the energy depletion from even a few nodes in the network can damage network integrity and reliability by creating holes in the network. In this paper, a composite energy-aware node metric ($RER_{BDI}$) is proposed for RPL; this metric uses both the residual energy ratio (RER) of the nodes and their battery discharge index. This composite metric helps avoid overburdening power depleted network nodes during packet routing from the source towards the destination oriented directed acyclic graph root node. Additionally, an objective function is defined for RPL, which combines the node metric $RER_{BDI}$ and the expected transmission count (ETX) link quality metric; this helps to improve the overall network packet delivery ratio. The COOJA simulator is used to evaluate the performance of the proposed scheme. The simulations show encouraging results for the proposed scheme in terms of network lifetime, packet delivery ratio and energy consumption, when compared to the most popular schemes for RPL like ETX, hop-count and RER.

• Journal of the Korean Physical Society
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• v.73 no.9
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• pp.1377-1384
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• 2018

Accurate measurement of the absorbed dose and the effective dose is required in dental panoramic radiography involving relatively low energy with a rotational X-ray tube system using long exposures. To determine the effectiveness of measuring the irradiation by using passive dosimetry, we compared the entrance skin doses by using a radiophotoluminescent glass dosimeter (RPL) and an optically stimulated luminescence detector (OSL) in a phantom model consisting of nine and 31 transverse sections. The parameters of the panoramic device were set to 80 kV, 4 mA, and 12 s in the standard program mode. The X-ray spectrum was applied in the same manner as the panoramic dose by using the SpekCalc Software. The results indicated a mass attenuation coefficient of $0.008226cm^2/g$, and an effective energy of 34 keV. The equivalent dose between the RPL and the OSL was calculated based on a product of the absorbed doses. The density of the aluminum attenuators was $2.699g/cm^3$. During the panoramic examination, tissue absorption doses with regard to the RPL were a surface dose of $75.33{\mu}Gy$ and a depth dose of $71.77{\mu}Gy$, those with regard to the OSL were surface dose of $9.2{\mu}Gy$ a depth dose of $70.39{\mu}Gy$ and a mean dose of $74.79{\mu}Gy$. The effective dose based on the International Commission on Radiological Protection Publication 103 tissue weighting factor for the RPL were $0.742{\mu}Sv$, $8.9{\mu}Sv$, $2.96{\mu}Sv$ and those for the OSL were $0.754{\mu}Sv$, $9.05{\mu}Sv$, and $3.018{\mu}Sv$ in the parotid and sublingual glands, orbit, and thyroid gland, respectively. The RPL was more effective than the OSL for measuring the absorbed radiation dose in low-energy systems with a rotational X-ray tube.

• 대한생식의학회:학술대회논문집
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• 2002.11a
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• pp.15-21
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• 2002

In order to keep the normal pregnancy, a number of gene products are required at the feto-matemal interface. We have isolated approximately 30 genes, involved in keeping the normal pregnancy, via subtractive hybridization and RT-PCR analyses of cDNAs from the chorionic villi of normal and RPL patients. Characterizing their functions will help us to understand the process of establishing and maintaining pregnancy. In addition, more detailed studies of their expression in normal and RPL patients are required to evaluate their clinical relevance. Further identification of genes aberrantly expressed in RPL patients will help the prognosis of the pregnancy, identifying pregnancies with a high risk of miscarriage and enabling management of those pregnancies.

• International Journal of Computer Science & Network Security
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• v.22 no.1
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• pp.255-261
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• 2022

Routing Protocol for Low-Power and Lossy Networks (RPLs) in Internet of Things (IoT) is currently one of the most popular wireless technologies for sensor communication. RPLs are typically designed for specialized applications, such as monitoring or tracking, in either indoor or outdoor conditions, where battery capacity is a major concern. Several routing techniques have been proposed in recent years to address this issue. Nevertheless, the expansion of the network lifetime in consideration of the sensors' capacities remains an outstanding question. In this research, aANN-CUCKOO based optimization technique is applied to obtain a more efficient and dependable energy efficient solution in IOT-RPL. The proposed method uses time constraints to minimise the distance between source and sink with the objective of a low-cost path. By considering the mobility of the nodes, the technique outperformed with an efficiency of 98% compared with other methods. MATLAB software is used to simulate the proposed model.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.1
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• pp.91-99
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• 2020

Objective: This study investigated the effects of oral administration of rumen-protected L-tryptophan (RPL-T) on duodenal starch digestion and gastrointestinal hormones (GIH) secretions using Hanwoo beef steers as the animal models. Methods: Four steers (423±24 kg) fitted with ruminal and duodenal cannulas were employed in a crossover design replicated twice. Treatments were control (basal diet) and RPL-T (basal diet+191.1 mg/kg body weight [BW]) group. Blood and duodenal samples were collected to measure serum GIH levels and pancreatic α-amylase activity at day 0, 1, 3, and 5 (-30, 30, 90, 150, and 210 min) of the study. Samples from each segment of the gastrointestinal tract were collected via ruminal and duodenal cannulas and were used to determine soluble protein and the starch digestion rate at days 6 (-30, 180, 360, and 540 min) and 8 (-30, 90, 270, and 450 min) of the experiment. Results: No significant difference in ruminal pH, NH₃-N, and total volatile fatty acid including the levels of acetate, propionate, butyrate, isobutyrate, valerate, isovalerate, and the acetate-to-propionate ratio was observed between groups (p>0.05). Crude protein uptake was higher and feces starch content was lower in RPL-T group than the control group (p<0.05). The D-glucose contents of feces in RPL-T group decreased at day 5 compared to those in the control group (p<0.05), however, no change was found at day 0, 1, or 3 compared to the control group (p>0.05). Serum cholecystokinin (CCK), melatonin, duodenal pancreatic α-amylase activity, and starch digestion were significantly higher in RPL-T group than the control group (p<0.05). Conclusion: Taken together, oral administration of RPL-T at the rate of 191.1 mg/kg BW consistently increased CCK concentration, pancreatic α-amylase activity in duodenal fluids, and starch digestion rate in the small intestine and thus found to be beneficial.

• Proceedings of the Safety Management and Science Conference
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• 2008.04a
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• pp.443-450
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• 2008

This paper is to present design principle and operation strategy of acceptance control chart by the use of OC-Based sampling inspection for continuous data. The unified control limits for acceptance control chart when considering both APL(Acceptable Process Level) and RPL(Rejectable Process Level) are proposed. The control limits can be also extended to the acceptance control chart with unknown process standard deviation.

• Journal of Korea Society of Industrial Information Systems
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• v.10 no.3
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• pp.48-56
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• 2005

This paper proposes a dynamic end-to-end flow control algorithm that is more effective than previous methods considering either the Rate of Packet Loss (RPL) or Round Trip Time (RTT). When the RPL is under normal conditions, the current network status will be in one of three defined states by using the RTT and this makes bandwidth control precise before serious packet loss occurs. If the RPL exceeds a critical level, then the network is considered to be in a fourth state. Suitable transmission rates are determined depending on the network status and are controlled by adjusting not only the number of transmitted frames but also the quality of the frames. In this paper, we present some experimental results of the proposed algorithm. According to our quantitative analysis, the proposed method performs 1.6 to 6 times better than the previous method in terms of the RPL. At the same time, the total number of transmitted packets is increased, which indicates that the proposed method can provide greater bandwidth capacity than previous methods.

• Journal of Korea Multimedia Society
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• v.2 no.4
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• pp.459-467
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• 1999

With fully harnessing the functions provided by Windows NT, we suggest the generating method of RPL profile and the RPL protocol for remote booting on DL-NCS(Network Computing System for Diskless client PCs). This system can offer clients, without having hard disk, boot remotely Window 9x stored in server's hard disk and can share peripheral devices and application programs in the server side. For booting Window 9x from DL-NCS, twenty-five clients' PCs were set for simultaneous on and finally the PCs were booted in similar time interval compared to that from a desktop PC having local disk. This system was also experimented to the application programs. And this system can yield excellent networking environments. In sum, with using this DL-NCS, we can reduce the installing costs of peripheral device, recycle the lower grade PCs such as 486SX/DX, and save the budgets for software purchase.

• Journal of the Korean Data and Information Science Society
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• v.18 no.2
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• pp.327-344
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• 2007

Ridge partial least squares regression (RPLS) is a regression method which can be obtained by combining ridge regression and partial least squares regression and is intended to provide better predictive ability and less sensitive to overfitting. In this paper, explicit expressions for the shrinkage factor of RPLS are developed. The structure of the shrinkage factor is explored and compared with those of other biased regression methods, such as ridge regression, principal component regression, ridge principal component regression, and partial least squares regression using a near infrared data set.