• 제목/요약/키워드: RPE1

검색결과 106건 처리시간 0.028초

결합된 수동물질취급 작업에서의 인체심리학적 연구 (Psychophysical Study of Combined Manual Material Handling Tasks)

  • 윤훈용
    • 산업경영시스템학회지
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    • 제22권50호
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    • pp.65-73
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    • 1999
  • Most psychophysical studies in manual material handling (MMH) have paid more attention to two-handed MMH activities than to one-handed MMH activities. Also, studies are involved only with single MMH activities - lifting, lowering, carrying, holding, pushing or pulling. Very few studies are reported on the determination of workers' capacities for combinations of one-handed MMH activities (lifting a box, then carrying the box, and lowering the box). The objective of this study was to find the psychophysical and physiological responses of human subjects from a simulated industrial task involving one-handed and two-handed combined tasks. The capacities that were determined as the maximum acceptable weight workloads for 1 hr work period for one-handed and two-handed combined tasks - lifting a box from floor to knuckle height, carrying the box for 4.3 m, and lowering the box from knuckle to floor height - were determined psychophysically under three frequencies: six handlings per minute, one handling per minute and one handling per five minutes. In addition to maximum acceptable weight, heart rate and RPE values on wholebody, back, and arm were also measured as responses.

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12주간 줄넘기, 밴드운동이 비만 여중생의 GH, IGF-1 및 대사증후군 위험 인자에 미치는 영향 (The Effect of 12 Weeks Rope Skipping and Band Exercise on GH, IGF-1 and Metabolic Syndrome Risk Factors in Female Obese Middle School Students)

  • 최공집;손원목
    • 한국응용과학기술학회지
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    • 제34권3호
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    • pp.587-594
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    • 2017
  • The purpose of this study was to investigate the effect of rope skipping and band exercise on GH, IGF-1 and metabolic syndrome risk factors in female obese middle school students. Twenty female obese middle school students(%BF > 30%) were randomly assigned to a exercise group(EX, n=10) or control group(CON, n=10). The exercise group has performed rope skipping and band exercise for 12 weeks, 3time per week. Exercise intensity was increased gradually, from 40% to 70% of Heart Rate Reserve(HRR) and Rating of Perceived Exertion(RPE) 11-15. GH, IGF-1 and metabolic syndrome rist factors were GH, IGF-1 and metabolic syndrome risk factors were measured pre- and post-exercise program including rope skipping and band exercise. Levels of GH and IGF-1 were significantly increased (p<.01 and p<0.001, respectively) in exercise group after 12 weeks of exercise training. WC and TG were significantly decreased(p<.01) in exercise group after 12 weeks of training. HDL-C was significantly increased(p<.05) in exercise group after 12 weeks of training. In conclusion, rope skipping and band exercise were effective exercise program in improving GH, IGF-1 and metabolic syndrome risk factors in female obese middle school students.

Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

  • Zhou, Wei;Quan, Juan-Hua;Gao, Fei-Fei;Ismail, Hassan Ahmed Hassan Ahmed;Lee, Young-Ha;Cha, Guang-Ho
    • Parasites, Hosts and Diseases
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    • 제56권2호
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    • pp.135-145
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    • 2018
  • Due to the critical location and physiological activities of the retinal pigment epithelial (RPE) cell, it is constantly subjected to contact with various infectious agents and inflammatory mediators. However, little is known about the signaling events in RPE involved in Toxoplasma gondii infection and development. The aim of the study is to screen the host mRNA transcriptional change of 3 inflammation-related gene categories, PI3K/Akt pathway regulatory components, blood vessel development factors and ROS regulators, to prove that PI3K/Akt or mTOR signaling pathway play an essential role in regulating the selected inflammation-related genes. The selected genes include PH domain and leucine- rich-repeat protein phosphatases (PHLPP), casein kinase2 (CK2), vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), glutamate-cysteine ligase (GCL), glutathione S-transferase (GST), and NAD(P)H: quinone oxidoreductase (NQO1). Using reverse transcription polymerase chain reaction (RT-PCR) and quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR), we found that T. gondii up-regulates PHLPP2, $CK2{\beta}$, VEGF, GCL, GST and NQO1 gene expression levels, but down-regulates PHLPP1 and PEDF mRNA transcription levels. PI3K inhibition and mTOR inhibition by specific inhibitors showed that most of these host gene expression patterns were due to activation of PI3K/Akt or mTOR pathways with some exceptional cases. Taken together, our results reveal a new molecular mechanism of these gene expression change dependent on PI3K/Akt or mTOR pathways and highlight more systematical insight of how an intracellular T. gondii can manipulate host genes to avoid host defense.

음악줄넘기가 남자중학생의 건강체력, 혈중지질, 성장관련인자에 미치는 영향 (Effects of Music Rope-Skipping exercise on health fitness, blood lipids and growth-related factors in male middle school Boys)

  • 김종원;김도연;강두왕;오덕자
    • 한국산학기술학회논문지
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    • 제13권8호
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    • pp.3405-3416
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    • 2012
  • 음악줄넘기가 남중생의 건강체력, 혈중지질 및 성장관련인자에 미치는 영향을 구명하기 위하여 G시에 거주하는 남자 중학생 20명을 대상으로 실시하였다. 운동프로그램은 12주간, 주 4회, 1일 45분, 1주기(1-6주)는 RPE 11-12(저강도), 2주기(6-12주)는 RPE 13-15로 실시하여 비교 분석한 결과 다음과 같은 결론을 얻었다. 첫째, 건강체력에서 각 집단 내의 음악줄넘기 실시 전 후의 변화에서 운동군은 제지방량, 근력, 근지구력, 심폐지구력, 유연성에서 유의하게 증가하였으나, 체지방률은 유의하게 감소하였다. 대조군은 근력, 근지구력, 심폐지구력에서 유의하게 증가하였으며, 각 집단 간의 변화량에 대한 차이검정에서는 제지방량, 체지방률, 근력, 유연성에서 유의한 차이가 나타났다. 둘째, 혈중지질에서 각 집단 내의 전 후의 변화에서 운동군은 HDL-C에서 유의하게 증가하였으나, 대조군은 TG에서 유의하게 감소하였으며, HDL-C는 유의하게 증가하였고, 각 집단 간의 변화량에 대한 차이검정에서는 모두 유의한 차이가 나타나지 않았다. 셋째, 성장관련인자에서 각 집단 내의 전 후의 변화에서 운동군은 성장호르몬, IGF-I에서 유의하게 증가하였다. 대조군은 IGF-I에서 유의하게 감소하였고, 각 집단 간의 변화량에 대한 차이검정에서는 IGF-I에서 유의한 차이가 나타났다. 이상의 연구결과에서 남자 중학생에게 음악줄넘기가 제지방량, 근력, 유연성, 성장호르몬, IGF-I에 긍정적인 효과가 있는 것으로 나타났다.

상악골 전방견인 장치의 효과와 안정성에 대한 두부방사선 계측학적 연구 (Clinical Effects and Stability of the Maxillary Protraction Using the Lateral Cephalogram in Korean)

  • 백형선
    • 대한치과교정학회지
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    • 제22권3호
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    • pp.509-529
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    • 1992
  • Skeletal Class III malocclusion is one of the most difficult type to treat and stabilize. For a child with developing skeletal Class III malocclusion, the treatment objective would be to stimulate maxillary growth, particulary one who has markedly deficient maxilla, and to restrain excessive mandibular growth. In order to stimulate the maxillary growth, maxillary protraction appliance is the one of the effective orthopedic appliances in skeletal Class III. The purposes of this study were as follows ; evaluation of the skeletal and dental changes of the maxillary protraction in children with Class III Maxillary deficiency , comparison of the clinical effects between the group with RPE and labiolingual intraoral appliances , comparison of the clinical effects and stability related to the ages of the patients : stability of the maxillary protraction about 1 year after retention. The subjects consisted of 60 children between the ages of 8 and 13.4 who were diagnosed as Class III with maxillary deficiency and were treated with Face Mask (Delaire Type) from the Dept. of Orthodontics Yong Dong Severance Hospital, Yonsei University. 48 children wore the RPE and 12 children wore Labiolingual Appliance. Lateral Cephalograms were taken for each patient at before and after correction of anterior cross-bite in 60 children, and after an observation period of 10 to 14 months in 19 children. X and Y coordinate of 10 landmarks were analyzed using a horizontal line through sella and rotated $6^{\circ}$ down anteriorly as the horizontal reference axis, and a perpendicular verticual line through sella as the vertical reference axis. Each of the 31 measurents (10 verticals, 10 horizontals, 2 angles and 9 others) was statistically analyzed using SPSS/PC statistics. The results are as follows; 1. After maxillary protraction the maxilla and maxillary teeth moved downward and forward, while the mandible and mandibular incisor rotated downward and backward. 2. Maxillary protraction with rapid palatal expansion appliance was more effective than with labiolingual appliance. 3. More downward movement of the posterior palatal plane obserbed with maxillary protraction doing the midpalatal suture opening than with protraction after finishing the palatal expansion 4. The clinical effects of protraction and changes of the retention periods were not statistically significant among the age groups. 5. During the retention period, maxilla and maxillary teeth, and mandible and mandibular teeth moved downward and forward, however the mandibular changes were larger than the maxillary changes.

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Experimental assessment for the photon shielding features of silicone rubber reinforced by tellurium borate oxides

  • M. Elsafi;Heba jamal ALasali;Aljawhara H. Almuqrin;K.G. Mahmoud;M.I. Sayyed
    • Nuclear Engineering and Technology
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    • 제55권6호
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    • pp.2166-2171
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    • 2023
  • In the present study, six silicone rubber doped by tellurium borate oxides were fabricated using the casting method. The densities of the fabricated silicon rubber-doped by tellurium borate oxides samples were measured using the Archimedes Method. Moreover, the linear attenuation coefficient of silicone rubber doped tellurium borate oxides samples was evaluated experimentally using the hyper pure germanium, and the recorded linear attenuation coefficient values were affirmed using the theoretical Phy-X program. The experimental measurements were performed using the narrow beam transmission method with radioactive isotopes Am-241, Cs-137, and Co-60 with energies of 59, 661, 1173, and 1332 keV. The linear attenuation coefficient values showed an enhancement by 4.73 times, 1.20 time, 1.17, time, and 1.17 time, respectively at gamma photon energies of 59, 661, 1173, and 1332 keV, when the TeO2 concentration increased in the fabricated composites from 0 to 50 wt%. The enhancement of the linear attenuation coefficient values has a positive effect on the transmission rate values where the half-value thickness and transmission rate were decreased accompanied by an increase in the RPE.

Analyses of physiological wrist tremor with increased muscle activity during bench press exercise

  • Son, Hyewon;Kim, Jisu;Hong, Gyuseog;Park, Wonil;Yoon, Sungjin;Lim, Kiwon;Park, Jonghoon
    • 운동영양학회지
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    • 제23권1호
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    • pp.1-6
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    • 2019
  • [Purpose] To date, there have been no studies on the response of wrist tremor to increased muscle activity during exercise. This study aimed to evaluate the wrist tremor response with increasing muscle activity during bench press exercise. [Methods] Triceps muscle activity and wrist tremor response were measured by electromyography and an accelerometer, respectively, during bench press exercise in 11 healthy men without weight-training experience. Subjects performed bench press at 30% repetition maximum (RM), and the rating of perceived exertion (RPE) and lactate concentration were measured before and after exercise. One week later, an equivalent number of bench presses at 30% RM was performed without weight load as a control trial (CT). [Results] RPEs and lactate concentrations significantly increased after resistance exercise (30% RM) from 7.4 to 14.3 and 1.7 to 4.9, respectively (P<.01), but no such difference was observed in the CT. Muscle activity linearly increased during the 30% RM exercise, and wrist tremors were shown to linearly decrease. A strong negative correlation was observed between the two variables (r=-0.88, P<.001). [Conclusion] We found that wrist tremors during resistance exercise, as measured using an accelerometer, can be used to predict muscle activity.

스위스 볼을 이용한 요부안정화 운동이 근력과 유연성 및 균형에 미치는 영향 (The Effects of Swiss Ball Lumbar Stabilization Exercise on the Strength and Flexibility, Balance)

  • 이동걸;안상현;오진규;조남정
    • 대한임상전기생리학회지
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    • 제7권1호
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    • pp.35-42
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    • 2009
  • Purpose : The purpose of this study was to investigate the effects of Swiss ball lumbar stabilization exercise on the strength and flexibility, balance for the subjects. 30 university students who aged an average $23.21{\pm}4.41$ years. Methods : The exercise program lasted for 4 weeks with a frequency of 3 times per week within 12 to RPE. The result was analyzed by case study were measured by sit-up for strength, and back muscle strength, and trunk flexion test and trunk extension lifting for flexibility, and also measured by balance test before and during, and after the Swiss ball exercise program. Statistical analysis was performed using SPSS/Win(15.0) version and t-test. Results : By the result of this study, we found that the number of performing sit-up strength was increased, and back muscle strength was increase, and trunk flexion test and trunk extension lifting was increased after the 4 weeks Swiss ball exercise program. Conclusion : These finding indicate that Swiss ball lumbar stabilization exercise using Swiss ball could be beneficial to the subjects. The effect of increasing strength and flexibility, balance was flexibility.

전단력이 연골세포에 미치는 영향에 관한 연구 (THE SHEAR STRESS PROTEOME OF CHONDROCYTES)

  • 김신엽;김성곤;최제용;남동석
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제27권1호
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    • pp.9-15
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    • 2005
  • The objective of this study is screening the shear stress related proteins in chondrocytes using twodimensional electrophresis and MALDI-TOF. C-28/I2 cell line were grown. The fluid-induced shear stress(FISS) was applied using a cone viscometer at a rotational velocity of 80rpm for periods of 12 hours. Control cultures were tested under identical conditions without mechanical load application. Collected samples were used for the two-dimensional electrophoresis and MALDI-TOF. The identified proteins were calcyclin, RPE-spondin, interleukin-2, extracellular signal regulated kinase (ERK), lamin B2, porA protein, and RET-ELE1 protein. All of them showed a decreased expression. In conclusion, seven proteins were identified as a shear stress related proteins in chondrocytes. As the destruction of articular cartilage is one of main pathogenesis of TMJ internal derangement, this study will give useful information for the understanding of the molecular aspect of TMJ disease.

Increased 26S proteasome non-ATPase regulatory subunit 1 in the aqueous humor of patients with age-related macular degeneration

  • Lee, Hyungwoo;Choi, Ae Jin;Kang, Gum-Yong;Park, Hyung Soon;Kim, Hyung Chan;Lim, Hyunjung Jade;Chung, Hyewon
    • BMB Reports
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    • 제47권5호
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    • pp.292-297
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    • 2014
  • Age-related macular degeneration (AMD) is the leading cause of blindness in the world. Evidence indicates that the suppression of the ubiquitin-proteasome system (UPS) contributes to the accumulation of toxic proteins and inflammation in retinal pigment epithelium (RPE), the functional abnormalities and/or the degeneration of which are believed to be the initiators and major pathologies of AMD. To identify new protein associations with the altered UPS in AMD, we used LC-ESI-MS/MS to perform a proteomic analysis of the aqueous humor (AH) of AMD patients and matched control subjects. Six UPS-related proteins were present in the AH of the patients and control subjects. Four of the proteins, including 26S proteasome non-ATPase regulatory subunit 1 (Rpn2), were increased in patients, according to semi-quantitative proteomic profiling. An LC-MRM assay revealed a significant increase of Rpn2 in 15 AMD patients compared to the control subjects, suggesting that this protein could be a biomarker for AMD.