• Title/Summary/Keyword: RIA

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Development of design framework based on reliability analysis using MATLAB (MATLAB 을 이용한 신뢰도 기반 설계 시스템 개발)

  • Sung, Young-Hwa;Kwak, Byung-Man;Maute, Kurt
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.1642-1647
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    • 2007
  • The aim of this research is to implement a design framework based on reliability analysis and make it possibly used for a reliable and robust design under uncertainties. Different types of reliability methods and algorithms are programmed to explore their characteristics. In our work, RIA and the PMA are employed for formulating the reliability analysis problems. A number of reliability methods are introduced in this program such as FORM, AMV/AMV+ and MCS. Reliability analysis can be easily performed with this tool box only if a drive file is ready to run. Users need to select random design variables and define their distributions and correlation.

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Preliminary Studies on the Measurement of the Free Thyroxine in the Serum by the Radioimmunoassay (방사면역측정법(放射免疫測定法)에 의한 혈중(血中) 유리(遊離) Thyroxine 농도측정(濃度測定)에 대(對)한 기초적(基礎的) 검토(檢討))

  • Lee, Joon-Il
    • Journal of radiological science and technology
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    • v.10 no.1
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    • pp.85-90
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    • 1987
  • Preliminary studies on the measurement of the free thyroxine in the serum with Amerlex $FT_{4}$ RIA kit were investigated using a tracer as $^{125}I-T_{4}$ derivative which is not almostly bound to thyroxine binding globulin, etc. The results are followed: 1. Linearity was tested on standards at various concentrations, and reproducibility and accuracy was excellent. 2. The antibody specificity is also excellent, and standard calibration curve of total $T_{4}$ was similar that of adding the TBG inhibitor. 3. Each value of $T_{4}$ in serum (the normal group, the hypothyroidism patients the pregnant women and the TBG dificiency patients) was not significant. As mentioned above, this method is more simple and rapid, compared to the other method.

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The analysis of metallothionein of acute cadmium poisoning - animal study - (카드뮴중독자 검색을 위한 메탈로치오네인 분석 -동물실험을 중심으로-)

  • 안령미
    • Journal of Environmental Health Sciences
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    • v.27 no.4
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    • pp.115-122
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    • 2001
  • The purpose of this study was to investigate the metallothionein of acute cadmium poisoning mice as a Cadmium index. Forty male ICR mice were injected with cadmium chloride solution from 1/8LD50 to 1/2LD50 dose. At 24 hours after exposed Cd, I examined Cd and metallothionein (MT) intissues(liver and kidney) and fluids(whole blood and urine) and also measured low molecular proteins, N-acetyl-D-glucosaminidase(NAG) and 2- microglobuline (2-MG) in urine. The concentration of Cd and MT of liver kidney whole blood and urine were increased with dose dependent manner. Urinary Cd and urinary MT and very good significance (p<0.01) and urinary MT had good significance with kidney Cd and NAG but not 2-MG Conclusionally MT in urine was very correlated with kidney Cd and urine Cd, So MT maybe useful as a Cd poisoning index.

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Development of Cloud Photo-stitching Application for 360 degree video converting based HTML5 (360도 영상 변환을 위한 HTML5기반 클라우드 포토스티칭 어플리케이션 구현)

  • Yoo, Sunggeun;Jung, Seo-kyung;Park, Sangil
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2017.11a
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    • pp.1-2
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    • 2017
  • 최근 기존의 설치형 어플리케이션으로 제공되던 워드 프로세서나 스프레드 시트 등이 RIA(Rich Internet Application)와 Ajax(Asynchronous JavaScript and XML)같은 기술의 발달로 구글 독스(Google Docs)와 같이 웹브라우저(Web Browser)에서 동작하는 형태의 클라우드 기반 웹 어플리케이션으로 제작되어 널리 사용되고 있다. 또한 기존의 웹 기술로는 구현하기 어려웠던 동영상 포맷 변환이나 사진이나 동영상에 필터를 적용하는 것과 같은 영상처리가 가능한 클라우드 기반 웹 어플리케이션이 등장하고 있는 실정이다. 이에 본 논문은 컴퓨팅 자원을 많이 사용하고, 장시간의 변환이 필요한 360도 영상의 변환과정에 꼭 필요한 기술인 포토스티칭(Photo-stitching)을 클라우드에서 가능하게 하는 프론트엔드 및 백엔드를 구현하고, 웹소켓(Websocket)기술을 활용하여 실시간으로 변환결과를 전달 받을 수 있도록 하였다.

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Fetal Sex Determination by RIA of Amniotic Fluid Testosterone and FSH (태아성별(胎兒性別)에 따른 양수중(羊水中) Testosterone과 F.S.H.의 동태(動態)에 관(關)한 연구(硏究))

  • Koh, Min-Whan;Shin, Myon-Woo
    • Clinical and Experimental Reproductive Medicine
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    • v.6 no.1_2
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    • pp.23-28
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    • 1979
  • To determine whether hormone analysis of amniotic fluid could be used for accurate determination of fetal sex, we measured testosterone(T) and follicle-stimulating hormone in 19 amniotic fluid samples. The mean T in amniotic fluid of 8 women earring male fetuses was 310 pg. per milliliter and of 11 women earring female fetuses was 150 pg. per milliliter (P<0.05${\ast}$). The mean amniotic fluid FSH of 1.16 mI.U. per milliliter for 7 women with male fetuses was over trifold lower than that for subjects with female fetuses. The mean amniotic fluid FSH of female fetuses was 3.85 mI.U. per milliliter (P<0.01${\ast}$) Measurement of T & FSH in amniotic fluid may be an adjunct method for fetal sex determination.

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Effect of Testosterone on Central Noradrenergic Nervous System and LHRH (중추 노르아드레날린성 신경계 및 황체호르몬 분비 촉진호르몬에 대한 테스토스테론의 영향)

  • 고홍숙;김경진;박종세;고광호
    • YAKHAK HOEJI
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    • v.35 no.4
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    • pp.295-300
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    • 1991
  • Ralationship between noradrenergic nervous system activity and luteinizing hormone releasing hormone(LHRH) content mediated by testosterone in hypothalamus was tested. Three groups of adult male animals were prepared; (1) Intact; (2) Castration+Vehicle (Cast+V); (3) Castration+Testosterone (Cast+T). Silastic capsule containing vehicle or testosterone was implanted into neck region of animals two weeks following castration. Norepinephrine content, alpha-adrenergic receptor binding characteristics using H$^{3}$-WB4101, and content of LHRH by LHRH RIA procedure were determined. Testosterone replacement to castrated male rats augmented the content of norepinephrine and LHRH. Testosterone replacement increased the alpha-adrenergic receptor density but did not change alpha-receptor affinity. The data from the present study suggest that increase in LHRH content by testosterone may be positively coupled to the activity of central noradrenergic nervous system.

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Effect of DDT on testosterone reduction through aromatase in leydig cell

  • Lee, Kyung-Jin;Shin, Dong-Weon;Kim, Ji-Young;Oh, Duk-Hee;Cho, Young-Rhan;You, Ho-Jin;Jeong, Hye-Gwang
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.05a
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    • pp.70-71
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    • 2003
  • Dichlorodiphenyltrichloroethane (DDT), is a widespread environmental pollutant. In this study, we investigated the effect of DDT on testosterone production through aromatase and investigated its molecular mechanism in testicular leydig cell, R2C. We investigated that the effects of DDT on testosterone production and its effects on aromatase activity in R2C cell by radio immunoassay (RIA). (omitted)

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Effect of Palmiwon on the Streptozotocin induced Prediabetic Model in Panceratic Bita Cells (췌장베타세포에서 스트렙토초토신으로 유도한 당뇨병 실험 모델에 대한 팔미원의 영향)

  • 이인순;이인자
    • Biomolecules & Therapeutics
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    • v.6 no.4
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    • pp.371-377
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    • 1998
  • The aim of the present study was to investigate the effect of Palmiwon on the type 1-prediabetic models induced by streptozotocin (STZ) in RINm5F cells and HIT-T15 cells. Palmiwon increased the cell proliferation and insulin release when pre- and post-treated for the STZ-exposed pancreatic beta cells. The cell proliferation and insulin release of these beta cells were measured by $^3$H-thymidine uptake and RIA, respectively. We also analyzed nutrients such as sugars, fatty acid and amino acids and minerals containing in Palmiwon using by gas chromatography, amino acid analyzer and AA spectrometer, respectively. Palmiwon seems to have protective and recovery properties on the prediabetic model in cellular level, which were ascribe to various nutrients and minerals containing in Palmiwon. From these results, it could be suggested that Palmiwon may be available as preventive and therapeutic prescription of type 1 diabetes mellitus.

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Puberty Related Changes in Hormonal Levels, Productive Performance, Carcass Traits, and Their Interactions in Slovakian White Gilts

  • Kolesarova, A.;Sirotkin, A.V.;Roychoudhury, S.;Capcarova, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.182-187
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    • 2010
  • The aim of this experiment was to evaluate the levels of hormones (progesterone, IGF-I and IGFBP-3) in blood plasma, growth, carcass traits and their interactions of sexually immature (n = 18) and sexually mature (n = 17) gilts. To calculate average daily weight gain (ADG), gilts were individually weighed at the beginning of the trial and at slaughter (110${\pm}$10 days old). Blood concentrations of progesterone, IGF-I and IGFBP-3 were determined by RIA. The right hot carcass sides were dissected and the individual basic parts from carcasses were weighed to record the carcass traits. IGFBP-3, ADG and carcass traits were not affected by pubertal maturation. Compared to sexually immature gilts, mature gilts had higher blood concentrations of progesterone and IGF-I. High correlations were noted between levels of some hormonal substances, productive performance and carcass traits of sexually immature and mature gilts.

Structural Optimization using Reliability Analysis (신뢰성 해석을 이용한 구조최적화)

  • Park, Jae-Yong;Lim, Min-Kyu;Oh, Young-Kyu;Park, Jae-Yong;Han, Seog-Young
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.19 no.2
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    • pp.224-229
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    • 2010
  • This paper presents a reliability-based topology optimization (RBTO) using bi-directional evolutionary structural optimization (BESO). An actual design involves uncertain conditions such as material property, operational load and dimensional variation. Deterministic topology optimization (DTO) is obtained without considering of uncertainties related to the uncertainty parameters. However, the RBTO can consider the uncertainty variables because it has the probabilistic constraints. In this paper, the reliability index approach (RIA) is adopted to evaluate the probabilistic constraint. RBTO based on BESO starting from various design domains produces a similar optimal topology each other. Numerical examples are presented to compare the DTO with the RBTO.