Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.05a
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- Pages.70-71
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- 2003
Effect of DDT on testosterone reduction through aromatase in leydig cell
- Lee, Kyung-Jin (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Shin, Dong-Weon (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Kim, Ji-Young (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Oh, Duk-Hee (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Cho, Young-Rhan (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- You, Ho-Jin (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Jeong, Hye-Gwang (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
- Published : 2003.05.01
Abstract
Dichlorodiphenyltrichloroethane (DDT), is a widespread environmental pollutant. In this study, we investigated the effect of DDT on testosterone production through aromatase and investigated its molecular mechanism in testicular leydig cell, R2C. We investigated that the effects of DDT on testosterone production and its effects on aromatase activity in R2C cell by radio immunoassay (RIA). (omitted)