• Title/Summary/Keyword: RI

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A Study on Planning Unit for Rural Development Programs considering Regional Characteristics (농촌의 지역적 성격을 고려한 지역개발단위검토)

  • 전영길
    • Journal of Korean Society of Rural Planning
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    • v.3 no.1
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    • pp.41-53
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    • 1997
  • In the study it is assumed that regional characteristics of each Ri within a Myeon are different in certain degrees. This assumption implies that in some case of rural planning, Goon(county) or Myeon may be inadequate as a planning unit. because regional characteristics within Myeon will vary in a considerable degree. The objective of this study is to obtain knowledge relevant to ascertaining planning units by classifying entire number of Ri in Ansung Goon according to the components of regionality, namely the degree of sustaining agriculture and the degree of urbanizing. There was a significant variation among Ri within a Myeon the degree of sustaining agriculture as well as in the degree of urbanizing. In this study it is implied that rural program planning of Goon as a whole seems to be irrelevant. And planning Myeon level programs needs eventually adjustments in such a way of eliminating areas(Ri) which are of inconsistent character. Some planning such as farming cooperation may be efficient if they are to be undertaken at Ri basis. If the program planning include such activities of marketing and cooperative use of facilities, a group of Ri in consistent nature of regionality can be a unit of planning.

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Pharmacognostical Studies on the Korean Folk Medicine 'BoRiSuNaMu' (민간약 보리수나무의 생약학적 연구)

  • Lee, Chang-Hun;Bae, Ji-Yeong;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.42 no.1
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    • pp.1-5
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    • 2011
  • Korean folk medicine 'BoRiSuNaMu' has been used mainly to cure apepsia and cough. With regard to the botanical origin of BoRiSuNaMu, it has been considered to be Elaeagnus species of Elaeagnaceae, but there was no pharmacognostical conformation on it. To clarify the botanical origin of 'BoRiSuNaMu', the anatomical characteristics of the branches of Elaeagnus species growing wild in Korea, Elaeagnus glabra, E. macrophylla, E. multiflora, E. submacrophylla, E. umbellata and E. umbellata var. coreana were studied. As a result, it was clarified that 'BoRiSuNaMu' was the branches of Elaeagnus umbellata.

Pharmacognostical Studies on the Korean Folk Medicine "NuRiJangNaMu" (민간약 누리장나무의 생약학적 연구)

  • Bae, Ji-Yeong;Ahn, Mi-Jeong;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.43 no.2
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    • pp.95-97
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    • 2012
  • Korean folk medicine 'NuRiJangNaMu' has been used mainly to cure neuralgia, arthritis, cough and abdominal lump. With regard to the botanical origin of NuRiJangNaMu, it has been considered to be Clerodendron species of Verbenaceae, but there was no pharmacognostical confirmation on it. To clarify the botanical origin of 'NuRiJangNaMu', the anatomical characteristics of the branches of Clerodendron species growing wild in Korea, Clerodendron trichotomum and Clerodendron trichotomum var. ferrugineum were studied. As a result, it was clarified that 'NuRiJangNaMu' was the branches of Clerodendron trichotomum.

Effect of Boiling Methods on the Physicochemical Properties of Su Ri Chwi (Synurus palmatopinnonatifidus var. indivisus KiTAM) Pectin (삶는방법이 수리취(Synurus palmatopinnonatifidus var. indivisus KiTAM.) 펙틴의 이화학적 특성에 미치는 영향)

  • 김명희;박용곤;장명숙
    • Korean journal of food and cookery science
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    • v.9 no.1
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    • pp.19-24
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    • 1993
  • The purpose of this study was to investigate the physicochemical properties of Su Ri Chwi (Synurus Palmatopinnonatifidus var. indivisus KiTAM.) cooked in different solution (distilled water, 1%, salt and 1% sodium bicarbonate added water) and time. The content of crude fiber showed the highest percentage among the alcohol-insoluble solids of cooked Su Ri Chwi. The contents of Ca and Mg were decreased by the addition of 1% sodium bicarbonate. The main neutral sugars of alcohol insoluble solids were arabinose, galactose, and glucose. The content of glucose was increased regardless of method used. The main neutral sugars of crude pectins were rhamnose, arabinose and glucose. Galactose was increased by the cooking. The gel chromatography on Sepharose CL-4B indicated that the pectin extracted from cooked Su Ri Chwi had lower molecular weight distribution than that of the raw Su Ri Chwi. Total pectin was decreased by the cooking method used. The amounts of soluble pectins of Su Ri Chwi cooked in 1% sodium bicarbonate added water were lower than those of raw material.

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Effects of TGF-${\beta}1$ Ribbon Antisense on $CCl_4$-induced Liver Fibrosis

  • Doh, Kyung-Oh
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.1
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    • pp.1-6
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    • 2008
  • Ribbon-type antisense oligonucleotide to TGF-${\beta}1$ (TGF-${\beta}1$ RiAS) was designed and tested to prevent or resolve the fibrotic changes induced by $CCl_4$ injection. When Hepa1c1c7 cells were transfected with TGF-${\beta}1$ RiAS, the level of TGF-${\beta}1$ mRNA was effectively reduced. TGF-${\beta}1$ RiAS, mismatched RiAS, and normal saline were each injected to mice via tail veins. When examined for the biochemical effects on the liver, TGF-${\beta}1$ mRNA levels were significantly reduced only in the TGF-${\beta}1$ RiAS-treated group. The results of immunohistochemical studies showed that TGF-${\beta}1$ RiAS prevented the accumulation of collagen and ${\alpha}$-smooth muscle actin, but could not resolve established fibrosis. These results indicate that ribbon antisense to TGF-${\beta}1$ with efficient uptake can effectively prevent fibrosis of the liver.

Inhibition of Nelumbo nucifera Stamens-derived Kaempferol on FcεRI-mediated GATA-1 Expression

  • Shim, Sun-Yup
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.350-353
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    • 2019
  • The transcription factor, GATA-1, plays an important role in the $Fc{\varepsilon}RI$ ${\alpha}$ chain expression in mast cells and basophils. This study was conducted to investigate the downregulation of the transcription factor GATA-1 by kaempferol isolated from Nelumbo nucifera stamens in $Fc{\varepsilon}RI$-mediated allergic reactions. Kaempferol inhibited $Fc{\varepsilon}RI$-mediated histamine release. Western blotting analysis and RT-PCR showed that the protein and mRNA expression of GATA-1 was suppressed by kaempferol in a dose-dependent manner. These results suggest that kaempferol may inactivate basophils by downregulating the $Fc{\varepsilon}RI$ ${\alpha}$ chain expression via the inhibition of the GATA-1 expression.

Pyrolysis Behavior of Pulverized Coal Particles at High Heating Rate (미분탄 입자의 고속가열 열분해거동 해석)

  • JANG, JIHOON;HAN, KARAM;YU, GEUN SIL;LIM, HYEON SOO;LEE, WOOK RYUN;PARK, HO YOUNG
    • Journal of Hydrogen and New Energy
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    • v.30 no.3
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    • pp.260-268
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    • 2019
  • The pyrolysis characteristics of pulverized coal particle was numerically analyzed with the drop tube furnace. Based on the simulated gas flow field in the drop tube furnace, the particle velocity, temperature and volatile evolution were calculated with the fourth order Runge-Kutta method. The effects of changes in reactor wall temperature and particle diameter on the pyrolysis behavior of coal particle were investigated. The particle heating rate was very sensitive to the reactor wall temperature and particle size, that is, the higher wall temperature and the smaller particle size resulted in the higher heating rate and the consequent quicker volatile evolution.

Directional Interpolation Based on Improved Adaptive Residual Interpolation for Image Demosaicking

  • Liu, Chenbo
    • Journal of Information Processing Systems
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    • v.16 no.6
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    • pp.1479-1494
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    • 2020
  • As an important part of image processing, image demosaicking has been widely researched. It is especially necessary to propose an efficient interpolation algorithm with good visual quality and performance. To improve the limitations of residual interpolation (RI), based on RI algorithm, minimalized-Laplacian RI (MLRI), and iterative RI (IRI), this paper focuses on adaptive RI (ARI) and proposes an improved ARI (IARI) algorithm which obtains more distinct R, G, and B colors in the images. The proposed scheme fully considers the brightness information and edge information of the image. Since the ARI algorithm is not completely adaptive, IARI algorithm executes ARI algorithm twice on R and B components according to the directional difference, which surely achieves an adaptive algorithm for all color components. Experimental results show that the improved method has better performance than other four existing methods both in subjective assessment and objective assessment, especially in the complex edge area and color brightness recovery.

Development of evaluation of B/F benzothiazole analogues for boron neutron capture therapy

  • Ji-ung Yang;Soyeon Kim;Kyo Chul Lee;Yong Jin Lee;Jung Young Kim;Ji-Ae Park
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.8 no.1
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    • pp.17-23
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    • 2022
  • Boron neutron capture therapy is a precision treatment technology that selectively destroys only tumor cells by irradiating thermal neutrons after accumulating boron drugs in tumor cells. Brain tumor is difficult to diagnose and treat due to the low permeability and targeting of drugs caused by the blood-brain-barrier. Crossing the BBB is essential for drug delivery to the brain. In this study, we designed and synthesized a novel compound incorporating benzothiazole to develop a boron drug with high BBB permeability and selectivity for brain tumor cells. In addition, their potential as a BNCT drugs was evaluated.

Preliminary research on the development of boron neutron capture therapy drugs

  • Soyeon Kim;Ji-ung Yang;Kyo Chul Lee;Jung Young Kim;Yong Jin Lee;Ji-Ae Park
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.1
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    • pp.3-10
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    • 2021
  • For successful boron neutron caputre therapy, it is essential to develop a boron drug with a selective accumulation capacity for tumors. In particular, in order to apply boron neutron caputre therapy to brain tumors, drugs with good blood-brain barrier penetration are required. In this study, two low-molecular-weight boron compounds were introduced as brain tumor boron neutron caputre therapy drugs, and their physical and biological efficacy were evaluated. Among them, B2 showed good blood-brain barrier permeability and a high brain/blood ratio. From these results, it is expected that B2 can be used as a useful boron drug for boron neutron caputre therapy in brain tumors.