• Journal of Sericultural and Entomological Science
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• v.51 no.2
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• pp.123-129
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• 2013

The purpose of this study is to investigate the effects of supplementation of mulberry powder, mulberry extract and silkworm powder during the 8 weeks of resistance exercise on muscle increase of rats. Fifty males, Sprague-Dawley rat, were randomly divided into 5 groups: CON(control group, n = 10), REG(resistance exercise group, n = 10), MP REG(mulberry powder intake and resistance exercise group, n = 10), ME REG(mulberry extract intake and resistance exercise group, n = 10) and SP REG(silkworm powder intake and resistance exercise group, n = 10). After climbing the ladder without weights during the 1 week of adaptation period, the rats in the resistance exercise group were trained to climb a 0.98-m vertical(80 degree incline) ladder with weights in their tail during 7 weeks(10 times each day, 2 days per week). After exercise, the skeletal muscle was extracted from the flexor hallucis longus. The absolute weight of skeletal muscle was measured by the electronic balance and the relative weight of skeletal muscle about the weight was calculated. The strength and density of legs muscle were analyzed by the computed tomography scan. After 8 weeks of resistance exercise, the absolute weight of skeletal muscle wasn't significant, but it increased in MP REG 8%, ME REG 8% and SP REG 10% compared to REG. The relative weight of skeletal muscle increased significantly in SP REG compared to REG (p < 0.05). Additionally, there was a significant increase of density and strength of the forelegs in SP REG compared to CON (p < 0.05). However, there was no significant increase of density and strength of the hind legs. In conclusion, regular resistance exercise made rats muscle increase and there was more muscle increase effected by providing silkworm.

• Journal of the Korean earth science society
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• v.32 no.7
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• pp.732-749
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• 2011

In this study, 27-year (1979-2005) regional climate over the CORDEX East Asia domain was reproduced using a regional climate model, RegCM4, driven by HadGEM2-AO output, and the model's simulation skill was evaluated in terms of surface air temperature and precipitation. The RegCM4 reasonably simulated the spatial distribution and interannual variability and seasonal variability of surface air temperature, while it had systematic biases in the simulation of precipitation. In particular, simulated rainband of East Asian summer monsoon was southward shifted below $30^{\circ}N$ as compared with the observation, thereby, summer mean precipitation over South Korea was significantly underestimated. Simulated temperature from the RegCM4 driven by the HadGEM2-AO output was comparable to that driven by the reanalysis. However, the RegCM4 driven by the HadGEM2-AO had prominently poor skill in the simulation of precipitation. This can be associated with the distorted monsoon circulations in the driving data (i.e., HadGEM2-AO) such as southward shifted low-level southwesterly, which resulted in the erroneous evolution of East Asian summer monsoon simulated by RegCM4.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2699-2703
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• 2012

The functional significance of the proteasome activator $REG{\gamma}$ in the regulation of cell proliferation and apoptosis has been recognized. However, pathological contributions to tumor development remain to be elucidated. Both oncogenic proteins and tumor suppressors are targeted by $REG{\gamma}$ for proteasomal degradation. It has been proposed that the role of the $REG{\gamma}$ in the pathogenesis of cancer is cell- and context-specific. In this study, we aimed to explore the potential involvement of $REG{\gamma}$ in laryngeal carcinomas, comparing protein expression in tumor and adjacent tissues by immunohistochemical staining and Western blot analysis. We also characterized the correlation between the expression of $REG{\gamma}$ and the previously identified substrates p53 and p21. We showed that $REG{\gamma}$ was abnormally highly expressed in cancer tissues. Statistical analysis revealed that there was a positive relationship between the level of $REG{\gamma}$ and the expression of p53 and p21. Our study suggests that $REG{\gamma}$ overexpression can facilitate the growth of laryngeal cancer cells.

• Molecules and Cells
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• v.44 no.9
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• pp.647-657
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• 2021

As a pancreatic inflammatory marker, regenerating islet-derived protein 3A (Reg3A) plays a key role in inflammation-associated pancreatic carcinogenesis by promoting cell proliferation, inhibiting apoptosis, and regulating cancer cell migration and invasion. This study aimed to reveal a novel immuno-regulatory mechanism by which Reg3A modulates tumour-promoting responses during pancreatic cancer (PC) progression. In an in vitro Transwell system that allowed the direct co-culture of human peripheral blood-derived dendritic cells (DCs) and Reg3A-overexpressing/ silenced human PC cells, PC cell-derived Reg3A was found to downregulate CD80, CD83 and CD86 expression on educated DCs, increase DC endocytic function, inhibit DC-induced T lymphocyte proliferation, reduce IL-12p70 production, and enhance IL-23 production by DCs. The positive effect of tumour-derived Reg3A-educated human DCs on PC progression was demonstrated in vivo by intraperitoneally transferring them into PC-implanted severe combined immunodeficiency (SCID) mice reconstituted with human T cells. A Reg3A-JAK2/STAT3 positive feedback loop was identified in DCs educated with Reg3A. In conclusion, as a tumour-derived factor, Reg3A acted to block the differentiation and maturation of the most important antigen-presenting cells, DCs, causing them to limit their potential anti-tumour responses, thus facilitating PC escape and progression.

• The Journal of Information Systems
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• v.30 no.1
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• pp.65-84
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• 2021

Purpose Based on the development of artificial intelligence and big data technologies, the RegTech has been emerged to reduce regulatory costs and to enable efficient supervision by regulatory bodies. The word RegTech is a combination of regulation and technology, which means using the technological methods to facilitate the implementation of regulations and to make efficient surveillance and supervision of regulations. The purpose of this study is to describe the recent adoption of RegTech and to provide basic examples of applying RegTech to capital market regulations. Design/methodology/approach English-based ontology and deep learning technologies are quite developed in practice, and it will not be difficult to expand it to European or Latin American languages that are grammatically similar to English. However, it is not easy to use it in most Asian languages such as Korean, which have different grammatical rules. In addition, in the early stages of adoption, companies, financial institutions and regulators will not be familiar with this machine-based reporting system. There is a need to establish an ecosystem which facilitates the adoption of RegTech by consulting and supporting the stakeholders. In this paper, we provide a simple example that shows a procedure of applying RegTech to recognize and interpret Korean language-based capital market regulations. Specifically, we present the process of converting sentences in regulations into a meta-language through the morpheme analyses. We next conduct deep learning analyses to determine whether a regulatory sentence exists in each regulatory paragraph. Findings This study illustrates the applicability of RegTech-based ontology and deep learning technologies in Korean-based capital market regulations.

• Proceedings of the Korean Statistical Society Conference
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• 2005.05a
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• pp.73-77
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• 2005

본 논문은 시계열에 내재된 설${\cdot}$추석 등 음력 명절효과의 존재를 검정하기 위해 RegARIMA 모형의 잔차에 대한 t-검정 통계량을 제시하였으며 Box-plot에 의한 그래프적 진단을 시도하였다. 제시된 t-검정 결과를 X-12-ARIMA의 AICC-사전검정 및 RegARIMA 모형에 의해 추정된 명절효과 회귀계수의 t-값과 비교하였다. 사용된 명절효과 변수는 Bell과 Hillmer(1983)의 명절효과 변수이다.

• Korean Journal of Community Nutrition
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• v.12 no.2
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• pp.160-167
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• 2007

This study was performed to investigate the effects of regular exercise on dietary factors and obesity indices among 407 healthy adult males subjects. Subjects were classified into regular exercise group (REG) and irregular exercise group (IREG). Two hundred and thirteen subjects of REG excercised regularly 3 times (more than 30 minutes/time) per week during more than last 1 month or more. One hundred and ninety-four of IREG (n = 194) didn't regularly exercise during the last 1 month. Obesity indices were BMI (Body Mass Index), WHR (Waist Hip Ratio) and PIBW (Percentage of Ideal Body Weight). And the mean BMI, WHR and PIBW of REG were (22.1, 0.90 and 105.8) significantly lower than those of IREG (25.7, 0.98 and 117.7) respectively. The mean daily starches, seeds, meats, eggs, fish, milk, fats and processed food intakes of REG were significantly lower than those of IREG And the mean daily vegetables, mushrooms and beverages intakes of the IREG were significantly lower than REG. Energy intake of REG and IREG were 1968.2 kcal and 1978.9 kcal respectively. Vitamin C intake of IREG was significantly lower than REG. But niacin and cholesterol intake of REG were significantly lower than the IREG. Exercise regularity was positively related with obesity indices and dietary factors. Therefore, it is necessary to exercise regularly to prevent obesity and cardiovascular disease in Korean adult males.

• The Korean Journal of Applied Statistics
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• v.27 no.7
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• pp.1257-1268
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• 2014

Since the introduction of KTX (Korea Tranin eXpress) in Korea reilway market, number of passengers using KTX has been greatly increased in the market. Thus, demand forecasting for KTX passengers has been played a importantant role in the train operation and management. In this paper, we study several time series models and compare the models based on considering special days and others. We used the MAPE (Mean Absolute Percentage Errors) to compare the performance between the models and we showed that the Reg-AR-GARCH model outperformanced other models in short-term period such as one month. In the longer periods, the Reg-ARMA model showed best forecasting accuracy compared with other models.

• Journal of Biomedical Engineering Research
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• v.10 no.1
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• pp.25-32
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• 1989

In this study, Rheoencephalography( REG ) was designed and constructed. Using the cons- tructed instrument cerebral blood flow(CBF) of left and right brain, CBF change by posture, and reproducibility were studied. Followings are important results. Relative CBF could be measured noninvasively and continuously. Since reproducibility of the constructed REG was found to be quite high (4%), the accuracy of the instrument itself was proved. REG can be easily applied for testing the effect of drugs for the patients with cerebral vessel diseases since it is quite sensitive to the relative changes of CBF. Various cerebral diseases can be diagnosed by analyzing the REG waveforms. The area of restricted cerebral blood vessels can be located by arranging the electrode configuration. Comparative studies with the standard techinques of measuring CBF are needed to verify the accuracy of REG. Further studies on optimal electrode configuration and various artifacts are also necessary.

• The Korean Journal of Community Living Science
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• v.19 no.2
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• pp.191-199
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• 2008

The purpose of this study was to obtain an understanding of the effect of regular exercise on obesity indices, the psychosocial wellbeing index, dietary factors and exercise regularity among 146 healthy mothers and 146 their daughters. "Mother" subjects were divided into two groups classified as regular exercise group(REG) and none exercise group(NEG). The exercise regularity of REG's daughters(30.8%) and of NEG's daughters (2.0%) was significantly different(p<0.001). The Obesity Indices(Body Mass Index (BMI), Waist Hip Ratio(WHR) and Percentage of Ideal Body Weight(PIBW)) of NEG's daughters were significantly higher than those of REG's daughters(p<0.001). But the psychosocial wellbeing index was not significantly different between REG's daughters and NEG's daughters. Intake of total energy, protein, fat, Ca, niacin and Fe were significantly different(p<0.001) between REG's daughters and NEG's daughters. Especially, vitamin C intake of REG's daughters was significantly higher than that of NEG's daughters(p<0.001). The exercise regularity of mothers was mainly related with Obesity Indices and nutrient intake in their daughters. Therefore, it might be necessary to maintain exercise regularity to prevent obesity and diet related problems in mothers and their daughters.