• 제목/요약/키워드: RBC value

검색결과 124건 처리시간 0.032초

학슬 및 관동화 에탄올 추출물의 항산화 및 항용혈 효과 (Antioxidant and Antihemolytic Activities of Ethanol Extracts of Carpesii Fructus and Farfarae Flos)

  • 강현주;김홍준;정승일;김현수;전인화;목지예;심재석;장선일
    • 대한본초학회지
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    • 제28권3호
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    • pp.25-31
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    • 2013
  • Objectives : To develop a natural antioxidant and anti-hemolytic agents, we investigated the effects of ethanol extracts of Carpesii Fructus and Farfarae Flos. Methods : Aerial parts of Carpesii Fructus and Farfarae Flos were extracted with 80% ethanol. Antioxidant activity of Carpesii Fructus or Farfarae Flos extract was evaluated by employing three different assays, i.e., 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-suphonic acid) diammonium (ABTS) scavenging and reducing power activities. Also, anti-hemolytic activity of Carpesii Fructus or Farfarae Flos extract was determined using [2,2'-azobis (2-methylpropionamidine) dihydrochloride (AAPH)]-induced hemolysis, glutathione (GSH) depletion and malondialdehyde (MDA) formation in normal rat red blood cells (RBC) or plasma. Results : The extracts obtained from Carpesii Fructus and Farfarae Flos dose-dependently increased the scavenging activity on DPPH- or ABTS-induced radicals and the reducing power activities. Carpesii Fructus and Farfarae Flos were similar to the scavenging activity and the reducing power of butylated hydroxy anisole effect at high concentration ($1,000{\mu}g/mL$). RBC oxidative hemolysis and plasma MDA formation induced by AAPH were significantly suppressed by the extracts of Carpesii Fructus and Farfarae Flos in a dose-dependent manner. Also, Carpesii Fructus and Farfarae Flos extracts prevented the depletion of cystosolic antioxidant GSH in RBCs. Carpesii Fructus generally had better than the free radical scavenging activity, the reducing power and anti-hemolytic effects of Farfarae Flos. Conclusions : These results suggest that Carpesii Fructus and Farfarae Flos may have value as the potential antioxidant and anti-hemolytic medicinal plant.

Sources of Trade Balance Dynamics in Korea

  • Kim, Jiwoon;Yu, Jongmin
    • Journal of Korea Trade
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    • 제26권2호
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    • pp.21-44
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    • 2022
  • Purpose - This study quantifies sources of trade balance dynamics over the business cycle in Korea. Specifically, we quantify the relative importance of domestic and foreign factors on trade balance dynamics using a small open economy real business cycle (SOE-RBC) model and provide policy implications for stabilization policies. Aggregate productivity and interest rate spreads are considered domestic factors affecting the trade balance. A world interest rate (the U.S. interest rate) is considered a foreign factor. Design/methodology - Following Neumeyer and Perri (2005), we build the SOE-RBC model with three types of shocks: aggregate productivity, interest rate spread, and world interest shocks. The model is estimated by the generalized method of moments (GMM) using relevant business cycle statistics. The estimated model is used for quantifying the relative importance of domestic and foreign factors on trade balance dynamics in Korea. Findings - Our main findings can be summarized as follows: 85.64% of the trade balance fluctuations in Korea are explained by domestic factors, the remaining 14.35% by foreign factors. Particularly, trade balance dynamics are mostly accounted for by the change in aggregate productivity shocks (85.58%). World interest rate shocks considerably explain trade balance (14.35%), whereas the role of interest rate spread shocks that represent domestic risks is limited (0.08%). Although aggregate productivity is key in explaining trade balance dynamics in Korea, interest rates still have an essential role. This is because aggregate productivity changes induce interest rate spread variations and, thus, the trade balance significantly. The results suggest that government policies mitigating fluctuations in aggregate productivity would be effective for stabilization policies in Korea by reducing the trade balance volatility. Originality/value - Existing studies on the emerging market business cycle examine mostly Latin American countries, and the main object of the studies is the volatility of consumption rather than trade balance dynamics. Conversely, our study examines Korea rather than Latin American countries. Additionally, we examine sources of trade balance dynamics, which are relatively more important in Korea, rather than those of the volatility of consumption. Hence, we estimate the model to explicitly match moments related to trade balance in the data.

회전형 반고정망 활성슬럿지 공법의 수학적 해석에 관한 연구 2. 슬럿지 생산량 및 축적과정과 유출수의 수질에 대하여 (STUDIES ON THE MATHEMATICAL KINETICS FOR THE REMOVABLE MOVING SCREEN MEDIA-ACTIVATED SLUDGE PROCESS)

  • 한웅전;한영호
    • 한국수산과학회지
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    • 제12권3호
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    • pp.175-179
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    • 1979
  • 대체로 활성슬럿지 공법에서 가장 큰 문제점은 처리후의 미생물의 분리, 슬럿지 반송, 잉여슬럿지의 소화이다. 반면에 생물학적 고정막을 이용한 RBC, 실수여과상, 고정층활성 슬럿지 공법들은 이와같은 문제가 해소된다. 최근 침전시설 및 농축조를 설치할 필요가 없느 반고정망 활성슬럿지 공법이 개발되었다. 이 공법은 최종 처분할 슬럿지량도 감소되며, 유출수의 수질도 양호하고 최대축척용량으로 유출수의 수질은 추정할 수 있으나, 반응조가 동적인 수리학적 양상의 결여 되어있었다. 따라서 본 연구에서는 반응조가 좀더 동적 수리학적 양상이 되도록 설계하여 운전하였으며 그 운전결과는 다음과 같다. REMSMAS 공법은 침전시설 및 농축시설없이도 양호한 유출수를 얻을 수 있었으며 슬럿지 부착능력도 RESMAS 공법이나 FAST 공법 보다 크게 나타났으며 최대축척용량에 도달되는 한계운전기일은 대략 유기물부하량에 비례하였다.

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회전원판공정과 화학침전공정 조합을 이용한 유기물과 질소*인의 동시제거 (Integrated System of RBC-lime Precipiatation for Simultaneous Removal of Organics and Nutrients)

  • 박종안;허준무;손부순
    • 한국환경보건학회지
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    • 제24권1호
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    • pp.132-140
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    • 1998
  • 회전원판공정(rotating biological contactorRBC)과 화학적 처리공정을 결합한 처리시스템을 이용하여 도시하수내 포함된 유기물과 영양염류를 제거할 경우에 수리학적 부하 (hydraulic loading)와 처리수 반송율 (recirculation rate)의 시스템 처리효율에 미치는 영향을 알아보고자 하였다. 각각의 수리학적 부하 0.031, 0.0535 및 0.076 $m^3/m^2/d에서 반송율을 100%, 200%, 300%로 변화시켰고, 질산화에 필요한 알카리도의 보충 및 화학적 처리를 위하여 lime(CaCO$_3$)을 가하여 유입수의 pH를 10.4-11.0으로 유지시켰다. 실험결과 수리학적 부하 0.0535 $m^3/m^2/d에서 BOD, COD의 제거효율이 가장 높게 나타났으며, 질산화 효율 및 질소 제거효율에서는 수리학작 부하 0.035 $m^3/m^2/d, 반송율 300%에서 가장 높았으며, 반송율별에서는 수리학적 부하를 고려할 때 300% 반송하는 것이 가장 높은 유기물 제거효율을 보였다. 반송율과 수리학적 부하를 증가시킬 경우에 발생되는 슬러지내 유기물 함량은 점점 증가하였고, 수리학적 부하 0.076 $m^3/m^2/d, 반송율 300%일 경우에는 유기물 함량이 47%로 매우 높았다. 이는 부하증가에 따른 미생물 성장의 증가와 더불어 수리학적 부하 증가에 따른 전단력의 증가가 영향을 미쳤기 때문이다. 인을 제거하기 위하여 pH를 10.4-11.0으로 유지시킨 경우에 인을 90%이상 제거할 수 있었으며, 유출수내 평균 SS농도는 40 mg/l를 상회하였다.

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GMR-SV 소자를 이용한 미크론 자성비드와 결합된 적혈구 검출 특성 연구 (Detection Characteristics of a Red Blood Cell Coupled with Micron Magnetic Beads by Using GMR-SV Device)

  • 이재연;김문종;이상석;이진규
    • 한국자기학회지
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    • 제24권4호
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    • pp.101-106
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    • 2014
  • Dc 마그네트론 스퍼터링법으로 자기저항비 5.0 %와 자장감응도 1.5 %/Oe를 갖는 glass/Ta(5.8 nm)/NiFe(5 nm)/Cu(2.3 nm)/NiFe(3 nm)/IrMn(12 nm)/Ta(5.8 nm) 다층구조 GMR-SV 박막을 증착하였다. 광 리소그래피 공정으로 적혈구 직경 크기인 $7{\mu}m{\sim}8{\mu}m$ 이내의 선폭인 GMR-SV 소자를 제작하였다. 직경 $1{\mu}m$ 크기인 여러 개의 자성비드가 결합된 적혈구를 자기저항비 1.06 % 자장감응도 0.3 %/Oe를 갖는 GMR-SV 소자에 떨어뜨려 -0.6 Oe 부근에서 약 $0.4{\Omega}$과 약 0.15 %의 변화를 관찰하였다. 본 연구로부터 미크론 크기의 선폭을 갖는 GMR-SV 소자가 자성비드를 결합한 적혈구내 헤모글로빈의 새로운 자성 특성을 분석하는 바이오센서로 활용할 수 있음을 보여주었다.

활성탄과 비타민 A의 급여가 거세 한우의 성장, 혈액성상 및 도체 특성에 미치는 영향 (Effects of Feeding Charcoal Powder and Vitamin A on Growth Performance, Serum Profile and Carcass Characteristics of Fattening Hanwoo Steers)

  • 김병기;김영직
    • Journal of Animal Science and Technology
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    • 제47권2호
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    • pp.233-242
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    • 2005
  • Effects of supplemental charcoal powder and vitamin A on growth performance, serum profile and carcass characteristics with 24 Hanwoo steers were inves$\ell$ated. The Hanwoo steers were randomly assigned to one of the three dietary treatments: 1) Control(commercial feed), 2) Tl(commercial feed supplemented with 2% charcoal powder and 0.2 % vitamin A), 3) T2(commercial feed with 2 % charcoal powder). In the age 26 month, body weight of control Tl and T2 were 633.8 kg, 621.0 kg, 619.4 kg, respectively, with not significantly different(P> 0.05). The daily weight gain of control was the highest followed by Tl and T2. The contents of vitamin A(retinol) and total cholesterol in the blood of Tl was higher Tl(56.32 $\ell$ / dt, 163.83 mg/ dz) than the other treatment groups(P < 0.05). The average of WBC value in the blood was 6.86-" 9.83 k / ${\mu}\ell$, RBC value was 7.98 - 11.26 k / ${\mu}\ell$ and blood platelet was 236.7 - 287.0 k / ${\mu}\ell$. But The serum profile in blood was not significantly different between control and treatment groups. The carcass grade and characteristics of all treatments in Hanwoo steers were not significantly different except the texture.

생약복합제제(生藥複合製劑)와 항암제(抗癌劑)의 병용투여(倂用投與)에 관한 연구(硏究) (제1보)(第1報) -가미삼령백출산(加味蔘笭白朮散)과 cis-Platin 병용투여(倂用投與)에 의한 부작용(副作用) 경감(輕減) 효과(效果)- (Studies on Combined Usage of Combined Preparation of Crude Drugs and Anti-neoplastic Drugs (I) -Alleviative Effect of Combined Usage of Gamisamryungbaekchool-San and cis-Platin on the Side Actions of cis-Platin-)

  • 김남재;홍남두;조종관;김진식;백승학
    • 생약학회지
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    • 제22권3호
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    • pp.197-206
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    • 1991
  • The water extract of Gamisamryungbaekchool-San increased the lifespan of mice implanted intraperitoneally with sarcoma 180. Significant depression of lethal toxicity of cis-platin $(45{\mu}M/kg,\;s.c)$ and renal toxicity (indicated by an increase in blood urea nitrogen value and creatinine value) of cis-platin $(35{\mu}M/kg,\;s.c)$ were observed in mice and rats treated with Gamisamryungbaekchool-San. RBC and WBC were significantly decreased in rats treated with cis-platin, and significant depression of hematologic toxicities of cis-platin $(35{\mu}M/kg,\;s.c)$ in rats treated with Gamisamryungbaekchool-San. After all, alleviative effect of the side actions of cis-platin was acknowledged by combined usage of Gamisamryungbaekchool-San and cis-platin.

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실험적으로 유발한 신부전 개에서 소아용 혈액투석기의 적용에 관한 연구 (Application of Pediatric Hemodialysis System to Experimental Renal Failure in Dogs)

  • 신현호;김완희;이충호;남치주;권오경
    • 한국임상수의학회지
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    • 제17권2호
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    • pp.340-345
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    • 2000
  • The purpose of the present study was to evaluate the possibility of application of pediatric hemodialysis system to dogs weighing less than 6 kg. Six healthy dogs (B .W, 3-6 kg) were used_ Experimental end-stage renal failure was induced by bilateral nephrectomy or bilateral ligation of ure-ters. Hemodialysis was performed when blood urea nitrogen (BUN) value increased over 90 mg/dl and every other day thereafter. Daily investigated parameters included clinical clinical signs such as vomiting, fecal appearance and activity and laboratory data such as PCV, WBC, RBC, BUN, creatinine, Ca, P, $Na^+ Cl^-and K^+$During hemodialysis treatment, BUN and creatinine values were measured hourly. Severe vomiting and inappetence were shown 2 days after infliction of kidney disorder and melena and mucous faces were observed 3 days. The signs were not corrected by hemodialysis treatment. Avel- age hemodialysis treatment time was $5.5 {\times} 0.7$,/TEX> hours until BUN value decreased to normal range. Abnor- mal hematological and electrolytes values were reduced within normal levels after hemodialysis treatments. The complications oft hemodialysis included vomiting, nausea, obstruction of intravascular catheter, tremor, seizure, temporary visual loss and continued decrease in PCV It is suggested that pediatric hemedialysis system can be applied to acute renal failure and acute toxicity. Further works on improvements in maintaining patency of catheter and in managing the complications of hemo- dialysis should be conducted.

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사슴의 혈액 및 혈액화학치에 관한 연구 (Blood and Serum Chemical Values on Deer Bred in Taegu Dalseung Park)

  • 이근우;장인호;송재찬;이동석
    • 한국임상수의학회지
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    • 제13권2호
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    • pp.127-129
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    • 1996
  • The study was conducted to determine normal blood and serum chemical values on deer. Normal blood and serum chemical values were studied in 8 healthy deers bred at Dalseung Park in Taegu. The values were analyzed with a blood chemical analyzer and calculated by Chawen's statistical analysis. The blood values of RBC, WBC and PCV were $9.73{\pm}1.19{\times} 10^{6}/{\mu}l, 3.37{\pm}0.88{\times}10^{3}/{\mu}l, 47.25{\pm}4.65 % respectively. The serum chemical value were: GOT; 83.0{\pm}39.4 IU/L, GPT; 50.12{\pm}25.83 IU/L, BUN; 36.63{\pm}8.70 mg/dl. CPK ; 1,296{\pm}495 IU/L, ALP; 238{\pm}54 IU/L, glucose; 143{\pm}52 mg/dl, total protein; 6.95{\pm}0.61 g/dl, amylase ; 116.0{\pm}34.5 IU/L,$ respectively. These values will be clinically helpful to diagnose the disease of deer.

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산양의 Anaplasmosis에 대한 역학적 조사 II . Terramycin을 이용한 치료시험 (A Studies on the Epidemiology of Caprine Anaplasmosis in Korea II. Therapy with Long Acting Terramycin)

  • 서석열;서이원;조선기;허철호;김동선;손구례;백병걸
    • 한국동물위생학회지
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    • 제17권1호
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    • pp.54-60
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    • 1994
  • Anaplasmosis is a tick-borne disease mainly of cattle, sheep, and goats. Anaplasmosis in goat had been reported at last year by authors. The disease brought the economic losses in the goat farm in Chonbuk province. In order to treat the disease, a long-acting formulation terramycin injectable solution was used experimental animals which indigenous goats were sick with moderate anemia. We were devided into two groups was treated with single dosage (20mg /kg of body weight). one group was treated with single injection, the other group was treated with twice of the same dosage intramusculary injection. The results indicate that the use of long-acting terramycin would minimize clinical signs of anaplasmosis infection in goat. After treament the differrences of hematological appearences and parasitaemia were observed in the effect of terramycin treatment. obviously, increased value of RBC. HB and HCT, and parasitaemia by means of Giemsa staining and acrydine orange staining was observed decreased due to treatment.

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