• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.7
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• pp.3207-3213
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• 2011

Most methods of color constancy, which is the ability to determine the object color regardless of the scene illuminant, have failed to meet our expectation of their performance especially about low-illuminated scenes. Some methods with high performance need to be developed, but we must, above all else, obtain experimental images for analyzing the required circumstances or evaluating the methods. Therefore, the paper produces new sets of images so that they can be used in the development of color constancy methods suitable for low-illuminated scenes. These sets are composed of two parts: one part of images which are synthesized with spectral power distribution(SPD) of illuminants, spectral reflectance curve of reflectances, and sensor response functions of camera; the other part of images where the intensity of each image is adjusted at the uniform rate. In an experiment, the use of the sets takes an advantage that its result images are analyzed and evaluated quantitatively as their ground truth data are known in advance.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.8A
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• pp.739-752
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• 2002

Recently, to utilize the limited bandwidth effectively, the concept of partial response (PR) signaling has widely been adopted in both the high-speed data transmission and high-density digital recording/playback systems such as digital microwave, digital subscriber loops, hard disk drives, digital VCR's and digital versatile recordable disks and so on. This paper is concerned with adaptive equalization of partial response channels particularly for the magnetic recording channels. Specifically we study how the PR channel equalizers work for different choices of desired or reference signals used for adjusting the equalizer weights. In doing so, we consider three different configurations that are actually implemented in the commercial products mentioned above. First of all, we show how to compute the theoretical values of the optimum Wiener solutions derived by minimizing the mean-squared error (MSE) at the equalizer output. Noting that this equalizer MSE measure cannot be used to fairly compare the three configurations, we propose to use the data MSE that is computer just before the final detector for the underlying PR system. We also express the data MSE in terms of the channel impulse response values, source data power and additive noise power, thereby making it possible to compare the performance of the configurations under study. The results of extensive computer simulation indicate that our theoretical derivation is correct with high precision. Comparing the three configurations, it also turns out that one of the three configurations needs to be further improved in performance although it has an apparent advantage over the others in terms of memory size when implemented using RAM's for the decision feedback part.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.745-754
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• 2021

The purpose of this study was to evaluate and verify the effectiveness of sustainable cosmetic raw materials developed from Gynostemma pentaphyllum, a plant native to Ulleungdo, in improving the skin barrier function and treating atopic dermatitis. Cells were derived from adult Gynostemma pentaphyllum plants, and suitable conditions for mass culture of the cells were established in a bioreactor. DNA components and amino acids extracted from this mass culture were identified from the HPLC fraction. In the in vitro efficacy evaluation results, changes in the expression levels of skin barrier-related proteins such as filaggrin (FLG) and Zonula occludens-1 (Zo-1) were insignificant. It was confirmed that the expression levels of the proteins thymic stromal lymphopoietin (TSLP) and interleukin-33 (IL-33) were significantly reduced. These results lead to the conclusion that Gynostemma pentaphyllum cell extracts have significant anti-inflammatory effects and that these extracts can be widely used as sustainable, nature-friendly active material in cosmetics with anti-inflammatory effects and targeted at improving atopic dermatitis.They may find use in anti-aging cosmetic products as well.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.6
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• pp.1249-1258
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• 2022

Marine debris is defined as a substance that is intentionally or inadvertently left on the shore or is introduced or discharged into the ocean, which has or is likely to have a harmful effect on the marine environments. In this study, the detection of marine debris and the analysis of the amount of change on marine debris were performed using the object detection method for an efficient method of identifying the quantity of marine debris and analyzing the amount of change. The study area is Yuho Mongdol Beach in the northeastern part of Geoje Island, and the amount of change was analyzed through images collected at 15-minute intervals for 32 days from September 12 to October 14, 2022. Marine debris detection using YOLOv5x, a one-stage object detection model, derived the performance of plastic bottles mAP 0.869 and styrofoam buoys mAP 0.862. As a result, marine debris showed a large decrease at 8-day intervals, and it was found that the quantity of Styrofoam buoys was about three times larger and the range of change was also larger.

• The Korea Journal of Herbology
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• v.34 no.5
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• pp.21-28
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• 2019

Objectives : In present study, we investigated a therapeutic effect and optimum dose of Socheongryong-Tang (SCT) on LPS-induced lung inflammation rats model. Methods : Male Sprague-Dawley rats ($260{\pm}10g$) were divided into 12 groups : Group 1 included the normal rats, and Group 2-12 were administrated LPS by intranasal injection to induce experimental lung inflammation. After 1 day of LPS administration, Group 3-9 were treated with SCT ${\times}1/4$, ${\times}1/2$, ${\times}1$, ${\times}3$, ${\times}6$, ${\times}12$ or ${\times}18$, respectively. Group 10-12 (positive control) were treated with dexamethasone 1 mg/kg or acetylcystein 1.5 mg/kg or diclofenac sodium 0.4 mg/kg, respectively. After sacrifice, bronchoalveolar lavage fluid (BALF) was isolated. The levels of IL-$1{\beta}$, TNF-${\alpha}$, mucin glycoprotein 5AC (MUG5AC) were measured in BALF using enzyme-linked immunosorbent assay (ELISA). Results : LPS injected rats exhibited outstanding lung inflammation manifestations, including increased amount of total cells and neutrophil, and upregulated inflammatory cytokines level in BALF. However, the administration of SCT ${\times}1/4$, ${\times}1/2$ and ${\times}1$ decreased total cells and neutrophil, and suppressed the production of inflammatory cytokines, including $IL-1{\beta}$ and TNF-${\alpha}$, and MUG5AC in BALF. Notably, inhibitory effect of SCT ${\times}1/2$ and ${\times}1$ on the level of TNF-${\alpha}$ was markedly better than that of positive controls, dexamethasone and acetylcystein. Conclusions : Taken together, these results suggest that SCT ${\times}1/2$ and ${\times}1$ has therapeutic effects on LPS-induced lung inflammation rats model.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.305-305
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• 2023

수문조사기기 검정은 강수량, 수위, 유량 등과 같은 수문자료를 관측하는 수문조사기기가 대상지역의 수문상황을 정확하게 관측하는지를 검사하는 일련의 과정으로 「수자원의 조사 계획 및 관리에 관한 법률」 제12조에 법적 기반을 두고 있다. 검정 대상은 강수량, 수위, 유속, 유사량, 토양수분량, 증발산량, 증발량 측정기기 총 7종이며, 환경부장관으로부터 한강홍수통제소가 검정업무를 위임받고, 한국건설기술연구원과 한국수자원조사기술원이 위탁받아 운영중에 있다. 최근에는 증발산량, 토양수분량 및 유량 측정기기기 등이 첨단화되어 기존 검정 방식에 대한보완 및 신설에 대한 요구가 증가하고 있다. 특히, 유량 측정시 기존에 사용하였던 회전식 유속계는 ADCP(Acoustic Doppler Current Profiler) 유량측정기기로 대체되어 활용률이 2013년 24%에서2021년 67%로 약 2.8배 급격히 증가하였다. 하지만 수문조사기기 검정 관련 고시 내 ADCP에 대한검사방법 및 허용오차 등의 규정이 부재하여 수문조사기기의 검정 공백이 발생하는 등의 문제가 존재하고 있다. 이에 본 연구에서는 ADCP 운영 및 기술 현황, 현행 법령, 국외 사례 등을 검토하여 ADCP 유량측정기기의 검사방법 및 허용오차에 대한 방안을 제시하고자 한다. ADCP 검사방법은 총 5단계로 외관검사, 자가진단 검사, 온도센서 검사, 수심측정 검사, 유량비교측정 검사에 따라 검정을 실시한다. 첫 번째 외관검사시에는 기기 외관과 센서 등 물리적 손상을 점검하고, 두 번째 자가진단 검사에서는 센서 변환 매트릭스 값, 수신부 센서 테스트, RAM/ROM 테스트, 통신 테스트 등에 관한 정상값 산출 여부를 확인한다. 세 번째 온도센서 검사에서는 검증용 온도센서를 이용한 값과 ADCP에 부착된 온도센서 값과 차이를 확인하고 ±2℃초과시 재검사 또는 적절한 조치를 취한 후 다음 단계의 검사를 진행한다. 네 번째 수심측정 검사에서는 수조 내 수심 측정을 확인하여 실제 수심과의 오차를 확인하고 ±1% 초과시 재검사 또는 적절한 조치 후 다음 검사를 실시한다. 유량비교 측정검사에서는 각 기기 간의 평균유량의 상대오차를 평가하는 것으로 ±5%미만에는 합격, ±5이상 ±10%미만에서는 재검사, ±10%이상에서는 공장수리를 권고하도록 하고, 1~5 단계의 검사를 통과한 기기를 대상으로 인증서를 발급하도록 한다. 유량비교 측정검사시에는 매년 ADCP를 사용하는 일반기업 및 공공기관 등이 모여 ADCP의 성능을 상호간 비교하는 'ADCP 기술협력 워크숍'을 확장하여 실시할 수 있다. 각 검사 단계의 허용오차는 USGS 또는 제조사 기준과 2022년 ADCP 기술협력 워크숍 성능검사 분석 결과를 토대로 하였다. 본 ADCP 검정 방안은 향후 ADCP 모델별로 단계별 시범 검토를 통해 세부사항에 대한 제시가 필요하며, 온도센서 검사, 수심측정 검사, 유량 비교측정검사에 대한 허용오차에 대한 타당성에대한 검증 및 검토가 이루어져야 할 것으로 사료된다.

• Journal of the Korean Association of Geographic Information Studies
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• v.27 no.1
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• pp.99-114
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• 2024

Domestic coastal debris monitoring encounters challenges due to labor-intensive methods and limited survey scope. Consequently, research is utilizing remote sensing techniques to enhance efficiency in data collection. However, standards for domestic remote sensing based monitoring methods remain insufficient. In this study, we conducted a meta-analysis of 19 coastal debris monitoring studies utilizing drones and other remote sensing devices. We analyzed data collection methods, collected data information, monitoring target details, monitoring status, detection targets, and utilization models. Based on our meta-analysis results, we proposed monitoring criteria, recommended items, and performance standards for monitoring coastal debris using drones. Our findings define necessary conditions and standards for establishing operational guidelines for coastal debris monitoring using drones. Furthermore, we anticipate that incorporating foreign case analyses and field application results will enable the development of national-level guidelines for coastal debris monitoring utilizing remote sensing devices.

• Journal of Korean Medicine for Obesity Research
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• v.24 no.1
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• pp.1-12
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• 2024

Objectives: Ephedrae herba (EH) and Coicis semen (CS) has been frequently prescribed for the treatment of obesity. However, effects of combinational extracts of these two herbs on non-alcoholic fatty liver disease are unknown. The aim of the present study was to investigate the effects of EH and CS on lipid accumulation and glucose absorption in free fatty acids (FFAs) or palmitic acid (PA)-treated HepG2 cells. Methods: Five samples of EH and CS were extracted by combination ratios (S1=0:100, S2=25:75, S3=50:50, S4=75:25, S5=100:0). Oil Red O staining was used to measure lipid accumulation in FFAs-induced steatosis cells. Intracellular triglycerides and total cholesterol levels were measured in FFAs-induced steatotic HepG2 cells. In PA-treated cells, intracellular 2-NBDG was detected using a fluorescence microplate reader and flow cytometry. Phosphorylation of key metabolism-related factors of AMP-activated protein kinase and acetyl-CoA carboxylase, expression of key lipid synthesis-related factors carnitine palmitoyltransferase 1 alpha (CPT1α), sterol regulatory element-binding protein 1 (SREBP1), peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT enhancer binding protein alpha (C/EBPα) were confirmed by western blot. Results: Treatment of EH-CS combination in the FFAs-induced steatotic HepG2 cells significantly reduced lipid accumulation. As the relative ratio of Ephedrae herba increased, the lipid-lowering effects of the combination were increased. However, S1 and S5 of Ephedrae herba and Coicis semen did not significantly reduce triglycerides and total cholesterol induced by FFAs. However, the combination of Ephedrae herba and Coicis semen restored glucose absorption in PA-induced HepG2 cells. Major makers of SREBP1, PPARγ, C/EBPα, and CPT1α expression tended to decrease with EH ratio. Conclusions: The EH-CS combination has advantages over sole EH and CS extracts in improving lipid and glucose metabolism in liver steatosis models.

• Microbiology and Biotechnology Letters
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• v.43 no.1
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• pp.45-55
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• 2015

This study was carried out to demonstrate the anti-inflammatory effect of tuna oil (TO) using LPS-induced inflammation responses and mouse models. First, nitric oxide (NO) and pro-inflammatory cytokines levels were suppressed up to 50% with increasing concentrations of TO without causing any cytotoxicity. Also, the expression of a variety of proteins, such as inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and nuclear factor kappa B (NF-κB), was suppressed in a dosedependent manner by treatment with TO. Furthermore, TO also inhibited the phosphorylation of mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and p38 protein kinase (p38). Moreover, in in vivo testing the formation of ear edema was reduced at the highest dose tested compared to that in the control, and a reduction of ear thickness and the number of mast cells was observed in histological analysis. In acute toxicity test, no mortalities occurred in mice administrated 5,000 mg/kg body weight of TO over a two-week observation period. Our results suggest that TO has a considerable anti-inflammatory property through the suppression of inflammatory mediator productions and that it could prove to be useful as a potential anti-inflammatory therapeutic material.

• Korean Journal of Food Science and Technology
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• v.54 no.1
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• pp.43-51
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• 2022

Regulation of the hair follicle cycle in association with dermal papilla cells is one of the most interesting targets for promoting hair regrowth. In this study, we examined whether steam-dried Betula platyphylla extracts (BPE) promote hair growth by upregulating in vitro and in vivo responses of dermal papilla cells. The data showed that BPE3 contained high amounts of phenolic compounds with higher antioxidant effects and increased hair growth-related genes, including fibroblast growth factor7 and Wnt7b, in dermal papilla cells. Notably, BPE3 effectively enhanced the formation of hair follicles by increasing FGF7, Wnt7b, and vascular endothelial growth factor in C57BL/6N dorsal skins. Additionally, BPE3 significantly decreased the expression of inflammatory repertoires, inducible nitric oxide synthase, interleukin-6, and cyclooxygenase 2. Several small molecules, such as betulin and unsaturated fatty acids, support the pharmacological activity of BPE3. In conclusion, BPE3 effectively promoted hair growth by activating dermal papilla cells and enhancing hair follicle cycles by attenuating the inflammatory environment in the scalp.