• Journal of the Korean Society for Nondestructive Testing
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• v.32 no.5
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• pp.502-508
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• 2012

Quantitative ultrasound technologies for osteoporosis diagnosis measure ultrasonic parameters such as speed of sound(SOS) and normalized broadband ultrasound attenuation(nBUA) in the calcaneus (heel bone). In the present study, the dependences of SOS and nBUA on bone mineral density in the proximal femur with high risk of fracture were investigated by using 20 trabecular bone samples extracted from bovine femurs. SOS and nBUA in the femoral trabecular bone samples were measured by using a transverse transmission method with one matched pair of ultrasonic transducers with a center frequency of 1.0 MHz. SOS and nBUA measured in the 20 trabecular bone samples exhibited high Pearson's correlation coefficients (r) of r = 0.83 and 0.72 with apparent bone density, respectively. The multiple regression analysis with SOS and nBUA as independent variables and apparent bone density as a dependent variable showed that the correlation coefficient r = 0.85 of the multiple linear regression model was higher than those of the simple linear regression model with either parameter SOS or nBUA as an independent variable. These high linear correlations between the ultrasonic parameters and the bone density suggest that the ultrasonic parameters measured in the femur can be useful for predicting the femoral bone mineral density.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6505-6510
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• 2014

Objective: This study was conducted to identify whether polymorphic variants of set domain-containing protein 8 (SET8) and tumor protein p53 (TP53) codon 72, either independently or jointly, might be associated with increased risk for cervical cancer. Methods: We genotyped SET8 and TP53 codon 72 polymorphisms of peripheral blood DNA from 114 cervical cancer patients and 200 controls using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct DNA sequencing. Results: The frequency of SET8 CC (odds ratios (OR) = 2.717, 95% CI=1.436-5.141) or TP53 GG (OR=2.168, 95% CI=1.149-4.089) genotype was associated with an increased risk of cervical cancer on comparison with the SET8 TT or TP53 CC genotypes, respectively. In additional, interaction between the SET8 and TP53 polymorphisms increased the risk of cervical cancer in a synergistic manner, with the OR being 9.913 (95% CI=2.028-48.459) for subjects carrying both SET8 CC and TP53 GG genotypes. Conclusion: These data suggest that there are significant associations between the miR-502-binding site SNP in the 3'-UTR of SET8 and the TP53 codon 72 polymorphism with cervical cancer in Chinese, and there is a gene-gene interaction.

• Plant Biotechnology Reports
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• v.4 no.1
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• pp.23-27
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• 2010

Quantitative trait loci (QTLs) controlling ability of somatic embryogenesis were identified in soybean. A frame map with 204-point markers was developed using an RI population consisting of 117 $F_{11}$ lines derived from a cross between cultivar 'Keburi' and a weedy soybean 'Masshokutou Kou 502'. The parents differed greatly in their abilities of somatic embryogenesis using immature cotyledons as explants. The ability of somatic embryogenesis was evaluated in five different experiments: the $F_{11}$ (evaluated in 1998) and $F_{15}$ (2002) generations cultured on basal media supplemented with $40\;mg\;l^{-1}$ 2,4-D (2,4-D1998 and 2,4-D2002), $F_{14}$ (2001) generation on medium with $40\;mg\;l^{-1}$ 2,4-D and high sucrose concentration [2,4-D2001 ($30\;g\;l^{-1}$ sucrose)], and the $F_{11}$ (1998) and $F_{12}$ (1999) generations on medium with $10\;mg\;l^{-1}$ NAA (NAA1998 and NAA1999). The RILs showed wide and continuous variations in each of the five experiments. In the composite interval mapping analysis, 2 QTLs were found in group 8 (D1b + W, LOD = 5.42, $r^2$ = 37.5) in the experiment of 2,4-D1998 and in group 6 (C2, LOD = 6.03, $r^2$ = 26.0) in the experiment of 2,4-D2001 (high concentration sucrose). In both QTLs, alleles of 'Masshokutou Kou 502' with high ability of somatic embryogenesis contributed to the QTLs. For the other three experiments, no QTL was detected in the criteria of LOD >3.0, suggesting the presence of minor genes.

• Journal of Ginseng Research
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• v.41 no.4
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• pp.496-502
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• 2017

Background: Ginsenosides are the major components of Panax ginseng Meyer, an herbal medicine used for the treatment of various diseases. Different ginsenosides contribute to the biological properties of ginseng, such as antimicrobial, anticancer, and immunomodulatory properties. In this study, we investigated the antiviral effects of 15 ginsenosides and compound K on gammaherpesvirus. Methods: The antiviral activity of ginsenosides was examined using the plaque-forming assay and by analyzing the expression of the lytic gene. Results: 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of murine gammaherpesvirus 68 (MHV-68), and its half-maximal inhibitory concentration ($IC_{50} $) against MHV-68 was estimated to be $2.77{\mu}M$. In addition, 20(R)-ginsenoside Rh2 inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpesvirus in the Kaposi's sarcoma-associated herpesvirus (KSHV)-positive cell line BC3. Conclusion: Our results indicate that 20(R)-ginsenoside Rh2 can inhibit the replication of mouse and human gammaherpesviruses, and thus, has the potential to treat gammaherpesvirus infection.

• Journal of Advanced Marine Engineering and Technology
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• v.27 no.4
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• pp.494-502
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• 2003

The near-tip field of mode-I dynamic cracks steadily propagating in a strain softening material is investigated under plane strain conditions. The material is assumed to be incompressible and its deformation obeys the $J_2$ flow theory of plasticity. A power-law stress-strain relation with strain softening is adopted to account for the damage behavior of materials near the dynamic crack tip. By assuming that the stresses and strain have the same singularity at the crack tip. this paper obtains a fully continuous dynamic crack-tip field in the damage region. Results show that the stress and strain components the same logarithmic singularity of (In(R/r))$\delta$, and the angular variations of filed quantities are identical to those corresponding to the dynamic cracks in the elastic-perfectly plastic material.

• Asia pacific journal of information systems
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• v.29 no.3
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• pp.489-502
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• 2019

The WeChat mini program is an application embedded in WeChat that users can use without downloading and installing. After it was officially released in 2017, many travel enterprises have launched their own mini programs on the WeChat platform. This study applies affordance theory to investigate the WeChat mini program's role in tourism activities through social network analysis using the R programming language. The authors searched the topic of "how do you perceive the travel-related WeChat mini program" and then crawled the 200 comments found; 180 comments were analyzed after data cleansing. The results show that travel-related WeChat mini programs play a very important role in Chinese social network tourism activities. This paper found that WeChat played a more active role in various tourism-related interactions with Chinese social networks. Moreover, the results show how affordance theory is applied to the use of WeChat mini programs.

• The Korean Journal of Woman Psychology
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• v.16 no.1
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• pp.97-113
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• 2011

The current study was conducted to explore the relations among college students' narcissistic personality, depression, and psychopathy. This study investigated how narcissistic personality and depression variables relate to psychopathy variables. For this purpose, an assessment battery consisting of Narcissistic Personality Inventory(NPI), Narcissistic Personality Disorder Scale: NPDS), BDI, Self-Reported Psychopathy Scale(SRPS), and Psychopathic Personality Inventory-Revised. PPI-R was administered to 1003 college students (501 males and 502 females). For comparison with the levels of pathological narcissism, the participants were devided two groups( above 33%, below 33% ) based on their scores of the NPDS, According to the results, males had more overt narcissistic personality, and females felt more depressive and psychopathic. The higher level group on the NPDS had higher scores on the NPI, BDI, SRPS and PPI-R. The students' narcissistic personality had relations to depression and psychopathy, but the results were different according to the kind of inventories(PPI-R or SRPS, NPI or NPDS). The implications and limitations of this study, as well as some suggestions for future research, were suggested.

• Proceedings of the Korea Concrete Institute Conference
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• 1995.04a
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• pp.136-141
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• 1995

The early evaluation on strength of concrete is useful to achieve on quality control and improvement of properties of concrete. Especially, we could say that the confidence of construction is increased by the increase durability and safety building, due to early evaluation. In this study, was proposed to ultra-sonic pulse method as a early evaluation method for strength of concrete with main parameter, sush as W/C ratio and S/A ratio. The experiment results are summarized to follow as : $\circled1$ The ultra-sonic pulse was decreased as the increase of W/C ratio. $\circled2$ The maximum value for the ultra-sonic pulse velocity and compressive strength was presented in the case of 40% S/A ratio and these value was decreased as the change of S/A ratio over 40% $\circled1$ The relationship of the ultra-sonic pulse velocity and compressive strength on 28days according to the change of W/C and S/A ratio is to be: $F_{28} = -209193R^2 + 384417R - 1763441$(W/C Ratio) $F_{28} = 1726R^2 - 774R - 502 (S/A Ratio)

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.502-509
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• 2007

Objectives : Folium perillae (FP) can relieve superficial pathogenic factors to dissipate cold and promote the circulation of qi and regulate the function of the stomach and is often used for interior qi-stagnation. We hypothesized that FP could rescue cerebral ischemia in rats. Methods : The present study was carried out to investigate the effects of FP on cerebral ischemia in terms of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in rats. Finally, lactate dehydrogenase (LDH) release was investigated, too. Results : In this study, treatment with FP elevated rCBF and MABP levels in dose-dependent manner. Pre-treatment with indomethacin, an inhibitor of cyclooxygenase, inhibited rCBF increase induced by FP effectively. However, FP did not affect stability during cerebral reperfusion. Finally, FP significantly inhibited LD H activity in vitro Conclusions : These results suggest that FP is useful to treat patient with diseases related to cerebral ischemia, because FP can increase rCBF and MABP.

• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.688-698
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• 2020

The purpose of this study is to identify the factors Job Embeddedness of a university hospital nurse. Data was collected from August 1 to August 10, 2017, for 238 nurses working at a university hospital in C city. Data were analyzed with descriptive statistics, t-test, ANOVA, and multiple linear regression. As a result of this study nursing organizational culture was 3.32±0.33, organizational communication satisfaction was 3.19±0.37, and job Embeddedness was 3.19±0.44. Job Embeddedness, nursing organization culture(r=.502, p<.001), and organizational communication satisfaction(r=.673, p<.001) were positively correlated. Factors affecting job Embeddedness are organizational communication satisfaction(β=.575 p<.001), work experience 'more than 10 years'(β=.342, p<.001), nursing organization culture(β=.203, p<.001), followed by work experience of more than 5 to less than 10 years(β=.121, p<.001), and the explanatory power of the model was 57.4%. According to the above results, it is necessary Job Embeddedness level of organizational communication satisfaction at any time and develop nursing practice and educational intervention programs in consideration of work experience and nursing organizational culture in order to increase the degree of access to nursing positions of hospital nurses.