• Journal of the Korean Society for Heat Treatment
• /
• v.13 no.4
• /
• pp.246-252
• /
• 2000

Stellite 12 alloy-powder was overlaid on 410 stainless steel valve seat using plasma transferred arc(PTA) process. Variation of characteristic of microstructure and hardness of deposit with current(90~150 A) and preheat temperature(R.T.~$400^{\circ}C$) was investigated. Important conclusion obtained are as follows; All welding conditions used produced a sound deposit layer with no defect in single pass welding. The maximum deposit had 4.0~4.8 mm in thickness and its bead width was increased with increase of current and preheat temperature. The deposit showed hypoeutectic microstruture, which was consisting of primary cobalt dendrite and networked $M_7C_3$ type eutectic carbides. The amount of eutectic carbides was decreased and its dendritic secondary arm spacing was increased with increase of current. Hardness of the deposit was decreased with increase of current. Preheat temperature up to $400^{\circ}C$, however, showed little influence on the hardness and microstructure. The hardness was also influenced by diluted Fe content near the interface in addition to microstructure and dendritic secondary arm spacing. Hot hardness at $500^{\circ}C$ showed higher than 300 HV.

• The Korean Journal of Food And Nutrition
• /
• v.35 no.6
• /
• pp.399-410
• /
• 2022

To enhance the bioavailability and bioactivities of mixed herbal medicines (RW), they were fermented with lactic-acid bacteria isolated from kimchi into postbiotics (FRW). Then, from the results of the 16s rRNA sequencing analysis, lactic acid bacteria isolated from kimchi were identified to be of two species, namely Lactobacillus sakei and Leuconostoc mesenteroides. The FRW prepared from the RW were extracted using hot water (HW) and 70% EtOH (EtOH) for comparison of their macrophage-stimulating activities. Based on a comparison of the activities of the FRW extracts, nitric oxide (NO) production of HW was significantly higher than that in EtOH. An analysis of the chemical properties of the extracts showed that HW had higher contents of neutral sugar and uronic acid than EtOH as well as contained a large amount of glucose. In addition, crude polysaccharide (CP) was prepared to enhance the macrophage-stimulating activity. The FRW-CP not only secreted immunostimulatory mediators but also increased the expression of immunostimulatory genes (iNOS, TNF-α, MCP-1, and IL-6). The fractionated FRW-CP contained about 90% neutral sugars, and these sugars were mainly composed of glucose, galacturonic acid, and arabinose. Thus, FRW prepared by fermentation of RW with kimchi lactic acid bacteria were found to be immunostimulatory modulators.

• Biomolecules & Therapeutics
• /
• v.31 no.4
• /
• pp.402-410
• /
• 2023

Long-term administration of levodopa (L-DOPA) to patients with Parkinson's disease (PD) commonly results in involuntary dyskinetic movements, as is known for L-DOPA-induced dyskinesia (LID). 5-Hydroxytryptophan (5-HTP) has recently been shown to alleviate LID; however, no biochemical alterations to aberrant excitatory conditions have been revealed yet. In the present study, we aimed to confirm its anti-dyskinetic effect and to discover the unknown molecular mechanisms of action of 5-HTP in LID. We made an LID-induced mouse model through chronic L-DOPA treatment to 6-hydroxydopamine-induced hemi-parkinsonian mice and then administered 5-HTP 60 mg/kg for 15 days orally to LID-induced mice. In addition, we performed behavioral tests and analyzed the histological alterations in the lesioned part of the striatum (ST). Our results showed that 5-HTP significantly suppressed all types of dyskinetic movements (axial, limb, orolingual and locomotive) and its effects were similar to those of amantadine, the only approved drug by Food and Drug Administration. Moreover, 5-HTP did not affect the efficacy of L-DOPA on PD motor manifestations. From a molecular perspective, 5-HTP treatment significantly decreased phosphorylated CREB and ΔFosB expression, commonly known as downstream factors, increased in LID conditions. Furthermore, we found that the effects of 5-HTP were not mediated by dopamine1 receptor (D1)/DARPP32/ERK signaling, but regulated by AKT/mTOR/S6K signaling, which showed different mechanisms with amantadine in the denervated ST. Taken together, 5-HTP alleviates LID by regulating the hyperactivated striatal AKT/mTOR/S6K and CREB/ΔFosB signaling.

• Journal of Energy Engineering
• /
• v.21 no.4
• /
• pp.402-410
• /
• 2012

A two-loop Rankine cycle for engine waste heat recovery of gasoline vehicle has been investigated. Water-steam cycle as a high-temperature (HT) loop for exhaust gas heat recovery and R-134a cycle as a low-temperature (LT) loop for both heat recovery of the engine coolant and the residual heat from the HT loop were considered. Energy and exergy analysis was performed to investigate the performance of the system. Because two volumetric expanders are used for the HT and LT loop, the sizes of two expanders are very important for the optimization of the system. The effects of pressure ratio of the HT loop, considering the size of the HT expander, and the condensation temperature of LT loop on the performance of the system at a target engine condition were investigated. This study shows that about 20% of additional power from the engine waste heat recovery can be obtained at the target engine condition.

• Korean Journal of Materials Research
• /
• v.32 no.1
• /
• pp.9-13
• /
• 2022

Bullets flying with a light from the back are called "tracers". Tracers are ignited by the combustion gas of the propellant and emit bright light that allows the shooter to visually trace the flight path. Therefore, tracers mark the firing point for allies to assist shooters to hit target quickly and accurately. Conventional tracers are constructed with a mixture of an oxidizing agent, raw metal, and organic fuel. Upon ignition, the inside of the gun can be easily contaminated by the by-products, which can lead to firearm failure during long-term shooting. Moreover, there is a fire risk such as forest fires due to residual flames at impact site. Therefore, it is necessary to develop non-combustion type luminous material; however, this material must still use the heat generated from the propellant, so-called "thermoluminescence (TL)". This study aims to compare the TL emission of Dy³⁺, La³⁺ and Ho³⁺ doped MgB₄O₇ phosphors prepared by solid state reaction. The crystal structures of samples were determined by X-ray diffraction and matched with the standard pattern of MgB₄O₇. Luminescence of various doses (200 ~ 15,000 Gy) of gamma irradiated Dy³⁺, La³⁺ and Ho³⁺ (at different concentrations of 5, 10, 15 and 20 %) doped MgB₄O₇ were recorded using a luminance/color meter. The intensity of TL yellowish (CIE x = 0.401 ~ 0.486, y = 0.410 ~ 0.488) emission became stronger as the temperature increased and the total gamma-ray dose increased.

• Polymer(Korea)
• /
• v.26 no.3
• /
• pp.410-414
• /
• 2002

The late transition Pd catalyst of low oxophilicity that has ferrocene -based diimine ligand for stabilization of center metal had been synthesized and applied for the polymerization of methyl methacrylate (MMA). In the presence of triisobutylaluminium (TIBA) for impurity scavenger, the effects of polymerization temperature and [TIBA]/[Pd] mole ratio on the yield and glass transition temperature ($T_g$) of PMMA had been examined. For 40~$50^{\circ}C$ of polymerization temperature and 2000~3000 of [TIBA]/[Pd] mole ratio, higher polymer yields were obtained. It was observed that ($T_g$) of PMMA is almost independent to the polymerization temperature but influenced by the [TIBA]/[Pd] mole ratio. With the examination of($T_g$) of PMMA with the structure of polymer, it had been found that T$_{g}$ of PMMA exhibits a linear relationship with the isotacticity of polymer.r.

• Journal of Digital Convergence
• /
• v.18 no.5
• /
• pp.405-410
• /
• 2020

Professionalism, objectivity, and fairness are highly required in the assessment of tasks in national research and development projects. Experts in the technologies should thus focus on the task's plan in the review process. The same scores in the assessment, however, do not mean that the judges don't have the same opinions. Another problem is the possibility that different weights can be applied for evaluation indexes. This study proposed an AHP-based assessment criteria decision system for national research and development tasks to reduce errors in task assessment and selection and improve the professionalism and fairness by objectifying the evaluation criteria of each index. As a result, the assessment criteria were objectified for each index in the projects. In addition, the professionalism and fairness of experts were secured in the process of setting assessment criteria for each index based on the given marks of weights.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2005.05b
• /
• pp.69-73
• /
• 2005

ACSR전력선의 송전용량 증가를 위해 개발된 중용량저이도 송전선인 STACIR/AW(Super Thermal-resistant Aluminum alloy Conductors, aluminum-clad Invar-Reinforced)전선은 초내열 Al도체 및 인바강선의 사용으로 비교적 고온에서의 안정적 운전이 가능하다. 그러나 고온 환경에서 장시간 노출된 STAClR/AW전선의 안정적 관리를 위해서는, 열화 된 STACIR/AW 전선의 인장강도, 각 구성소재의 탄성계수, 비틀림 계수 등과 같은 기계적 물성이 장기 운전 모의를 위해 선정된 열화온도, 열화시간 등에 대해 종합적으로 평가될 필요가 있다. 또한 크립 등과 같이 고온응력 부하상태에서의 변형거동과 탄성계수 및 선팽창계수의 온도의존성 등은 전선의 이도관리와 예측을 위해서도 명확히 규명되어야할 중요한 관리 인자이다. 그러나 현재까지는 이들에 대해 수행한 어떠한 연구결과들도 보고 되어 있지 않은 실정이다. 본 연구에서는 STACIR/AW $410mm^2$ 송전선을 장시간 운전의 모의를 위해 가속열화 시키고 가속열화에 따른 STACIR/AW 전선 및 그 구성소재의 강도, 비틀림 특성의 변화를 조사하여 장시간 운전에 따른 STACIR/AW전선의 안정성을 평가하여 보고하고자 하였다.

• Journal of Digital Contents Society
• /
• v.18 no.2
• /
• pp.403-410
• /
• 2017

In this paper, the fire extinguisher maintenance system using smart NFC communication and the real-time pressure measurement is proposed. The proposed system consists of three steps in the flow of information. The first step is to identify the fire extinguisher through NFC tagging in the fire extinguisher module using the smart device. The fire extinguisher appearance check and the real-time pressure measurement is performed in the second step, and the last step sends the check status information to the management server. In particular, the actual pressure value is calculated based on the angle of the green area and the indicating needle. Some experiments are conducted so as to verify the proposed system, and as a result, the proposed system shows that the administrator can effectively control the status information of fire safety check.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.4
• /
• pp.414-421
• /
• 2018

In this study, Gram-positive bacilli (GPB) were identified by MALDI-TOF MS and analyzed according to the quaternary and microbial strains in the blood culture medium over a two year period at a university hospital. The results were as follows. The overall positive rate of blood culture was 9.97%. In 713 isolated GPB, 410 strains (57.5%) were identified using a microflex MALDI Biotyper. The positive rate of GPB among the blood culture positive bacteria was 8.2%, and the quarterly isolation rate was 9.8% in the third quarter of 2015, 8.7% in the second quarter of 2016, 8.1% in the third quarter of 2016, 8.1% in the first quarter of 2015, 7.9% in the first quarter of 2015, 7.9% in the second quarter of 2015, 6.8% in the first quarter of 2016, and 6.7% in the fourth quarter of 2015. The isolates were Corynebacterium striatum 89 (12.4%), Bacillus cereus 60 (8.4%), Bacillus subtilis 30 (4.2%), Paenibacillus urinalis 29 (4.1%), and Listeria monocytogenes 25 (3.5%). The results of 16S rRNA sequencing of 43 isolates (86.0%) were consistent with those of the other 50 isolates. Five out of the seven unmatched weeks were not identified by MALDI-TOF MS.