• Title/Summary/Keyword: R3 코다

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REPAIR OF BILATERAL CLEFT LIP AND NOSE: PRINCIPLES AND METHODS OF MULLIKEN (양측 구순열비의 교정술: Mulliken의 원칙과 방법)

  • Jung, Young-Soo;Mulliken, John B.;Sullivan, Stephen R.;Padwa, Bonnie L.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.4
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    • pp.353-360
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    • 2009
  • The principles for repair of bilateral cleft lip and nasal deformity are 1) symmetry, 2) primary muscular continuity, 3) proper philtral size and shape, 4) formation of the median tubercle and vermilion-cutaneous ridge from lateral labial elements, and 5) primary positioning of the alar cartilages to construct the nasal tip and columella. The authors underscore the essential role of preoperative premaxillary positioning for the synchronous closure of the cleft lip and primary palate, and describe Mulliken's operative technique. We discuss three-dimensional adjustments based on predicted fourth-dimensional changes. In a consecutive series of 50 patients, no revisions were necessary for philtral size or columellar length. Preoperative premaxillary positioning and primary repair of bilateral cleft lip and nasal deformity may impair maxillary growth. Nevertheless, a symmetric nasolabial appearance, rather than emphasis on maxillary growth, is the priority for the child with bilateral cleft lip.

Fabrication and Characterization of Low Noise Amplifier using MCM-C Technology (MCM-C 기술을 이용한 저잡음 증폭기의 제작 및 특성평가)

  • Cho, H.M.;Lim, W.;Lee, J.Y.;Kang, N.K.;Park, J.C.
    • Proceedings of the International Microelectronics And Packaging Society Conference
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    • 2000.11a
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    • pp.61-64
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    • 2000
  • We fabricated and characterized Low Noise Amplifier (LNA) using MCM-C (Multi-Chip-Module-Cofired) technology for 2.14 GHz IMT-2000 mobile terminal application. First, We designed LNA circuits and simulated it's high frequency characteristics using circuits simulator. For the simulation, we adopted high frequency libraries of all the devices used in LNA samples. By the simulation, Gain was 17 dB and Noise Figure was 1.4 dB. We used multilayer process of LTCC (Low Temperature Co-fired Ceramics) substrate and conductor, resistor pattern for the MCM-C LNA fabrication. We made 2 buried inductors, 2 buried capacitors and 3 buried resistors. The number of the total layers was 6. On the top layer, we patterned microstrip line and pads for the SMT device. We measured the high frequency characteristics, and the results were 14.7 dB Gain and 1.5 dB Noise Figure.

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Characteristics of Related Companies and Process of Japanese Co-operative Housing (일본의 Co-operative Housing 관련 회사 및 프로세스 특성)

  • Park, Jee-Hyun;Bae, Jung-Yoon;Song, Min-jung;Yoo, Bok-Hee;Yoon, Chung-Sook
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2003.11a
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    • pp.207-212
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    • 2003
  • Today, demands on the housing that is fit f3r each and every person and restoration of the community are increasing rapidly. USA Europe and Japan have been constructing Co-operative Housing as an alternative residence. Therefore this study has a purpose to show the characteristics of related companies and the process of Japanese Co-operative Housing through the field trip in Japan.

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Pimecrolimus ($Elidel^{(R)}$, SDZ ASM1981) (엘리델$^{(R)}$(피메크로리무스)크림 $1\%$ 전임상 약리학 성상 및 피부 선택성)

  • 한국임상약학회
    • Korean Journal of Clinical Pharmacy
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    • v.13 no.2
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    • pp.97-105
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    • 2003
  • 아스코마이신(ascomycin)의 macrolactam 유도체인 피메크로리무스(pimecrolimus; 엘리델 [Elidel], SDZ ASM 981; Novartis Pharma AG, 바젤, 스위스)는 세포선택성을 지닌 염증성 사이토카인(cytokines) 억제제로서 아토피피부염, 알레르기성 접촉피부염, 자극성 접촉피부염 및 판형 건선 등 염증성 피부질환의 치료제로 개발되었다. T세포와 비만세포의 염증성 사이토카인 생산 분비를 억제하고 사전 형성된 염증성 매개물질의 비만 세포 분비를 저해한다. 국소 투여된 피메크로리무스는 알레르기성 접촉피부염(allergic contact dermatitis [ACD]) 돼지 모델에서 고역가 코르티코스테로이드 클로베타졸-17-propionate(corticosteroid clobetasol-17-propionate)와 동등한 효과를 나타낸다. 하지만 피메크로리무스는 클로베타졸과는 달리 피부 위축을 일으키지 않는다. 경구 투여시 피메크로리무스는 마우스와 랫트 ACD 치료에 있어서 타크로림무스(tacrolimus [FK 506])와 동등한 혹은 더 우수한 효과를 나타낸다. 또한 피메크로리무스는 아토피피부염 급성 징후 유사 모델인 저마그네슘 혈증 탈모 랫트(hypomagnesemic hairless rat)의 피부 염증과 소양증을 효과적으로 감소시킨다. 피메크로리무스는 랫트에서 다음과 같은 측면의 전신 면역반응 손상 효과가 타크로리무스 와 비교하여 낮게 평가된다: (1)국소 이식편대 숙주 반응, (2)양(sheep) 적혈구에 대한 항체 형성, (3)신장이식. 시험관내 평가시 돼지 피부를 통한 피메크로리무스 투과 속도가 타크로리무스보다 10배 낮게 측정되므로 생체에서 경피 흡수가 더 적게 될 것으로 판단된다. 상기 자료로 판단컨대 피메크로 리무스는 피부에 대한 항염증 활성이 높을 뿐 아니라 전신 면역반응 손상 부작용이 낮은것으로 사료된다.

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A Study for Designing the Zonal Canvas Type of Stow Net (띠 전개범식 안강망어구의 연구)

  • KIM Dae-An;KO Kwan Soh
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.18 no.1
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    • pp.1-7
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    • 1985
  • Various types of shearing devices which may be a substitute for the conventional beams in stow nets were considered, and then tentatively named "the zonal canvas type of stow net" having the shearing device made of zonal canvas was devised. A 1/3 model of the net was made and experimented at sea. Converted to the full scale, the measured water resistance R(kg) of the net was given by $R=5.6{\times}10^{3}V^{l.5}$ or $R=3.5\frac{d}{l}{\lambda}_b{\lambda}_l\;V^{1.5}$, where V is the water velocity (m/sec), d the diameter of netting bars, l the length of the bars, ${\lambda}_b$ the stretched circumference of net mouth (m), ${\lambda}_l$ the length of net stretched. The net height kept about $83\%$ of the side rope length regardless of the variation of V and the net breadth kept a value over $90\%$ of the head rope length until V reached 1 m/sec. These results were very successful according to expectation, but the conventional netting was requested a further improvement. Therefore, the netting was newly designed to have smaller size of meshes in the vicinity of net mouth and larger hanging ratio breadthwise. With the netting a full scale net was made and experimented by a stern trawler. The experiment gave a net breadth over $95\%$ of the head rope length until V reached 1m/sec and showed no faults in the net. But the net operation by the stern trawler was ascribed an inconvenience to its narrow breadth of stern slip way.

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The Gaiting Behaviour of the Shrimp Macrobrachium nipponense on the Nettings (망지에 대한 징거미 새우(Macrobachium nipponense)의 보행운동)

  • KIM Yong-Hae;KO Kwan-Soh
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.18 no.3
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    • pp.235-242
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    • 1985
  • The mechanics of the walking shrimps is useful to clarify the fishing mechanisms in relation to the fishing gears. The gaiting behaviour concerning step positions and step timings on the flat board and the nettings, 16, 23 and 37mm in mesh size were experimented in the aquarium using video camera from June to October, 1984. It was found that the irregular movements of walking legs in step positions and step patterns were appeared on the nettings more than the flat surface due to the absence of mechanical contact with the substrates. The mean stride length and coefficient of variation of the periods in the walking shrimps on the flat board were significantly different from those values on the nettings, However, the velocity, the period and the ratio of forestroke to backstroke were unsteadily changed with the carapace length, and showed little difference under the four conditions. The mean phase difference on the flat board was greater than those values on the nettings which were decreased, while standard deviation on the flat board was smaller than those values on the nettings which were increased with increasing in mesh size.

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Flow Resistance and Modeling Rule of Fishing Nets -2. Flow Resistance of Bag Nets- (그물어구의 유수저항과 모형수칙 -2. 자루형 그물의 유수저항-)

  • KIM Dae-An
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.2
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    • pp.194-201
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    • 1995
  • In order to make clear the resistance of bag nets, the resistance R of bag nets with wall area S designed in pyramid shape was measured in a circulating water tank with control of flow velocity v and the coefficient k in $R=kSv^2$ was investigated. The coefficient k showed no change In the nets designed in regular pyramid shape when their mouths were attached alternately to the circular and square frames, because their shape in water became a circular cone in the circular frame and equal to the cone with the exception of the vicinity of frame in the square one. On the other hand, a net designed in right pyramid shape and then attached to a rectangular frame showed an elliptic cone with the exception of the vicinity of frame in water, but produced no significant difference in value of k in comparison with that making a circular cone in water. In the nets making a circular cone in water, k was higher in nets with larger d/l, ratio of diameter d to length I of bars, and decreased as the ratio S/S_m$ of S to the area $S_m$ of net mouth was increased or as the attack angle 9 of net to the water flow was decreased. But the value of ks15m was almost constant in the region of S/S_m=1-4$ or $\theta=15-90^{\circ}$ and in creased linearly in S/S_m>4 or in $\theta<15^{\circ}$ However, these variation of k could be summarized by the equation obtained in the previous paper. That is, the coefficient $k(kg\;\cdot\;sec^2/m^4)$ of bag nets was expressed as $$k=160R_e\;^{-01}(\frac{S_n}{S_m})^{1.2}\;(\frac{S_m}{S})^{1.6}$$ for the condition of $R_e<100$ and $$k=100(\frac{S_n}{S_m})^{1.2}\;(\frac{S_m}{S})^{1.6}$$ for $R_e\geq100$, where $S_n$ is their total area projected to the plane perpendicular to the water flow and $R_e$ the Reynolds' number on which the representative size was taken by the value of $\lambda$ defined as $$\lambda={\frac{\pi d^2}{21\;sin\;2\varphi}$$ where If is the angle between two adjacent bars, d the diameter of bars, and 21 the mesh size. Conclusively, it is clarified that the coefficient k obtained in the previous paper agrees with the experimental results for bag nets.

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Improved Estimation of Hourly Surface Ozone Concentrations using Stacking Ensemble-based Spatial Interpolation (스태킹 앙상블 모델을 이용한 시간별 지상 오존 공간내삽 정확도 향상)

  • KIM, Ye-Jin;KANG, Eun-Jin;CHO, Dong-Jin;LEE, Si-Woo;IM, Jung-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.25 no.3
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    • pp.74-99
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    • 2022
  • Surface ozone is produced by photochemical reactions of nitrogen oxides(NOx) and volatile organic compounds(VOCs) emitted from vehicles and industrial sites, adversely affecting vegetation and the human body. In South Korea, ozone is monitored in real-time at stations(i.e., point measurements), but it is difficult to monitor and analyze its continuous spatial distribution. In this study, surface ozone concentrations were interpolated to have a spatial resolution of 1.5km every hour using the stacking ensemble technique, followed by a 5-fold cross-validation. Base models for the stacking ensemble were cokriging, multi-linear regression(MLR), random forest(RF), and support vector regression(SVR), while MLR was used as the meta model, having all base model results as additional input variables. The results showed that the stacking ensemble model yielded the better performance than the individual base models, resulting in an averaged R of 0.76 and RMSE of 0.0065ppm during the study period of 2020. The surface ozone concentration distribution generated by the stacking ensemble model had a wider range with a spatial pattern similar with terrain and urbanization variables, compared to those by the base models. Not only should the proposed model be capable of producing the hourly spatial distribution of ozone, but it should also be highly applicable for calculating the daily maximum 8-hour ozone concentrations.

Flow Resistance of Plane Nettings for Net Cages (우리 그물용 평면 그물감의 유수저항)

  • KIM Tae-Ho;KIM Dae-An;RYU Cheong-Ro
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.34 no.3
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    • pp.254-259
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    • 2001
  • In order to make clear the resistance of plane nettings u,sed widely in constructing net cages, the resistance R taken by $R=kSU^2$, where S was the wall area of nettings, U the flow velocity, and k the resistance coefficient, was measured in a circulating water channel by using nylon Raschel nettings and PE trawler-knotted nettings coated with anti-fouling paint or not and then the properties of coefficient k were investigated. The mesh size L and the angle $\phi$ between two adjacent bars was given by the function of Reynolds number ${\lambda}U/v$ in the region of ${\lambda}U/v<180$, i. e., $$k=350(\frac{\lambda U}{v})^{-0.25}$$.where $\lambda$ was the representative size of nettings expressed as $$\lambda=\frac{{\pi}d^2}{2L\;sin\;2{\phi}}$$On the other hand, the coefficient k was almost fixed between 92 and 102 ($kg{\cdot}s^2/m^4$) in the region of ${\lambda}U/v{\geq}180$ and varied according to the ratio $S_n/S$ of the total area $S_n$ of nettings projected to the plane perpendicular to the water flow to the wall area S of nettings, i.e., it was given by $$k=98.6(\frac{S_n}{S})^{1.19}$$ regardless of the coating of paint.

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Development of $^1H-^{31}P$ Animal RF Coil for pH Measurement Using a Clinical MR Scanner (임상용 MR에서 pH 측정을 위한 동물 실험용 $^1H-^{31}P$ RF 코일 개발)

  • Kim, Eun Ju;Kim, Daehong;Lee, Sangwoo;Heo, Dan;Lee, Young Han;Suh, Jin-Suck
    • Investigative Magnetic Resonance Imaging
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    • v.18 no.1
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    • pp.52-58
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    • 2014
  • Purpose : To establish a pH measurement system for a mouse tumor study using a clinical scanner, to develop the $^1H$ and 31P radio frequency (RF) coil system and to test pH accuracy with phantoms. Materials and Methods: The $^1H$ and the $^{31}P$ surface coils were designed to acquire signals from mouse tumors. Two coils were positioned orthogonally for geometric decoupling. The pH values of various pH phantoms were calculated using the $^1H$ decoupled $^{31}P$ MR spectrum with the Henderson-Hasselbalch equation. The calculated pH value was compared to that of a pH meter. Results: The mutual coil coupling was shown in a standard $S_{12}$. Coil coupling ($S_{12}$) were -73.0 and -62.3 dB respectively. The signal-to-noise ratio (SNR) obtained from the homogeneous phantom $^1H$ image was greater than 300. The high resolution in vivo mice images were acquired using a $^{31}P$-decoupled $^1H$ coil. The pH values calculated from the $^1H$-decoupled $^{31}P$ spectrum correlated well with the values measured by pH meter ($R^2$=0.97). Conclusion: Accurate pH values can be acquired using a $^1H$-decoupled $^{31}P$ RF coil with a clinical scanner. This two-surface coil system could be applied to other nuclear MRS or MRI.