• ALGAE
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• 제19권4호
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• pp.293-301
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• 2004

여수해만에서 분리한 Gymnodinium catenatum의 성장에 있어서 최적 수온과 염분 조건을 파악하기 위해 수온 6단계,염분 5단계의 조합에 의한 30단계의 배치배양을 실시하여, 성장속도를 계산하였다. C. catenatum은 약 18${^{\circ}C}$ 이상의 수온과 전 염분단계에서 0.3day$^{-1}$ 이상의 성장속도를 보였으며 수온의 감소와 함께 성장속도도 감소하였다. 하지만 염분은 성장에 그다지 영향을 미치지 않았다. 최대성장속도(0.5day$^{-1}$)는 수온 25${^{\circ}C}$와 염분 30psu에서 얻어졌다. 따라서, 수온과 염분에 따른 성장속도를 고려할 때, C. catenatum은 이른 여름부터 가을까지 한국남해연안해역에서 서식 가능한 것으로 판단된다 이 종의 출현을 예측하기 위한 모델식은 $\mu$ = 0.005-T$^2$ - 0.0001164 T$^3$ - 0.063-S + 0.005-S$^2$ - 0.00007608-S$^3$ - 0.003-T-S + 0.00005308-T$^2$-S로 나타났다. 한편. 수온 18${^{\circ}C}$와 염분 30psu 조건하에서 6단계의 광도 실험을 실시한 결과, 광량에 따른 C. catenatum의 성장은 $\mu$ = 0.16 (I - 10.4)/(1+21.8), (r=0.96)의 관계식으로 Ks는 42.6$\mu$mol m$^{-2}$s$^{-1}$, I$_0$는 10.4$\mu$mol m$^{-2}$s$^{-1}$이었다. 따라서 수온, 염분과 광 조건만을 고려할 경우 C. catenatum은 고수온기 한국 남해 내만과 연안해역에서 우점종으로 출현할 가능성이 높을 것으로 판단되었다.

• 한국패류학회지
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• 제27권1호
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• pp.1-7
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• 2011

전라남도 고흥해역의 바지락을 채집하여 연령과 성장에 대하여 조사하였다. 각장에 대한 각고, 각폭, 전중량의 상대성장식에서 상관계수 ($r^2$)는 0.8003-0.9053의 범위로 비교적 높은 상관관계를 나타났다. 윤문의 평균 윤경은 $SL_{1.58}=12.51{\pm}2.55\;mm$, $SL_{2.58}=20.27{\pm}3.08\;mm$, $SL_{3.58}=26.90{\pm}2.49\;mm$, $SL_{4.58}=31.35{\pm}3.62\;mm$, $SL_{5.58}=35.45{\pm}3.54\;mm$, $SL_{6.58}=38.78{\pm}4.04\;mm$로 나타났으며, 평균 전중량은 $TW_{1.58}$ = 0.35 g, $TW_{2.58}$ = 4.62 g, $TW_{3.58}$=5.84 g, $TW_{4.58}$ = 6.71 g, $TW_{5.58}$ = 7.50 g, $TW_{6.58}$ = 8.14 g로 나타났다. Bertalanffy 성장식을 구한결과는 $SL_t = 51.01(1-e^{-0.1738(t+1.07)})$ $TW_t=11.65(1-e^{-0.1738(t+1.07)})^{2.9519}$로 나타났다.

• Archives of Pharmacal Research
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• 제26권7호
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• pp.569-574
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• 2003

Controlled-release amitriptyline pellets (ATP) were formulated and its oral bioavailability was assessed in human volunteers after oral administration under fasting conditions. Core pellets were prepared using a CF granulator by two different methods (powder layering and solvent spraying) and coated with Eudragit RS or RL 100. Physical characteristics and dissolution rates of core pellets and coated pellets were evaluated to optimize the formulation. Powder layering method resulted in a better surface morphology than solvent spraying method. However, physical properties of the products were poorer when prepared by powder layering method with respect to hardness, friability and density. The dissolution profile of amitriptyline coated with Eudragit RS 100 was comparable to that of commercially available amitriptyline enteric-coated pellets ($Saroten^{\circledR}$ retard). After the oral administration of both products at the dose of 50 mg, the mean maximum concentrations ($C_{max}$) were 36.4 and 29.7 ng/mL, and the mean areas under the concentration-time curve ($AUC_{0-96}$) were 1180.2 and 1010.7 ng.h/mL for ATP and Saroten retard, respectively. The time to reach the maximum concentrations ($T_{max}$) was 6 h for both formulations. Statistical evaluation suggested that ATP was bioequivalent to Saroten retard.

• 한국임상약학회지
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• 제13권2호
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• pp.67-71
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• 2003

The purpose of this study was to investigate the effect of aspirin (5, 10, 20 mg/kg) on the pharmacokinetics of metformin $(15\;mg/kg)$ in rabbits. The plasma concentration of metformin was decreased significantly (p<0.05) by co-administration of aspirin (10, 20 mg/kg) compared with control. Area under the plasma concentration-time curve (AUC) of metformin was decreased significantly (p<0.05) by co-administration of aspirin (10, 20mg/kg) compared with control. Relative bioavailability $(R.B\%)$ of metformin by co-administration was 79.3 (5 mg/kg), 57.5 (10 mg/kg) and 62.5 (20 mg/kg). Peak plasma concentration of metformin was significantly (p<0.05) decreased by co-administration of aspirin (10, 20 mg/kg) compared with control. The elimination rate constant $(K_{el})$ of metformin was increased by co-administration of aspirin (10, 20 mg/kg) compared with control. The terminal half-lifes $(t_{1/2})$ and mean resident time (MRT) of metformin by co-administration of aspirin (10, 20 mg/kg) were decreased significantly (p<0.05) compared with control. It is considered that the significantly decreased plasma concentration and AUC of metrormin is due to increase of elimination in urine acidified by co-administration of aspirin. The results suggest that the dosage of metformin should be adjusted when metformin is co-administered with aspirin in the clinical situation.

• 한국정밀공학회지
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• 제28권9호
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• pp.1070-1077
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• 2011

This study intends to assess the defect in the weld zone of titanium grade 2 plate in terms of acoustical anisotropy based on the angle beam method. Depending on the rolling direction, the ratio of wave velocity was found to be 1.08 and the difference in the angle of refraction was more than seven degrees, confirming the presence of acoustical anisotropy. Thus for measuring the length of defect in the weld zone of the titanium plate (thickness of 10mm), the distance amplitude characteristics curves of titanium, TDACC-R and TDACC-T were constructed for the measurements in consideration of the acoustical anisotropy on CRT of the ultrasonic testing equipment. As a result, when the distance amplitude characteristics curve corresponds to the rolling direction, the length of defect was close to the actual measurement within 1mm and when different, the difference was found to be over 4mm. It was affirmed that the acoustical anisotropy should be taken into consideration when measuring the length of defects in the weld zone of the titanium plate with the presence of acoustical anisotropy.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2002년도 추계학술발표대회 논문집
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• pp.60-63
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• 2002

Metal/intermetallic laminated composites have been manufactured by SHS reactions between Ni and Al elemental metal foils. Microstructure showed that the intermetallic volume fraction was 55%, 45%, 35% in the 1:1, 2:1, 4:1 thickness ratio(Ni:Al) specimen and the main phases of the intermetallic were transformed from $Ni_2Al_3$ to NiAl when the thickness ratio was increased. Tensile strength and elongation were increased when the volume fraction of Ni metallic phase was increased. Under assumptions of isostrain condition, the tensile strength of metal/intermetallic laminated composites didn't obey the ROM due to the thermal residual stress and this was confirmed by X-ray residual stress analysis. Fracture toughness results by the SENB test showed R-curves with upward curvature based on LSB condition. Bridging stress based on LSB condition was determined by the curve fitting analysis, In-situ observed microstructure during fracture test showed that the various bridging mechanism such as crack bridging, crack branching and ductile failure of metallic layer were occurred

• Coupled systems mechanics
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• 제3권3호
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• pp.247-265
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• 2014

This article discusses the dynamic response of Bernoulli-Euler straight beam with angular elastic supports subjected to moving load with variable velocity. A new engineering approach for determination of the dynamic effect from the moving load on the stressed and strained state of the beam has been developed. A dynamic coefficient, a ratio of the dynamic to the static deflection of the beam, has been defined on the base of an infinite geometrical absolutely summable series. Generalization of the R. Willis' equation has been carried out: generalized boundary conditions have been introduced; the generalized elastic curve's equation on the base of infinite trigonometric series method has been obtained; the forces of inertia from normal and Coriolis accelerations and reduced beam mass have been taken into account. The influence of the boundary conditions and kinematic characteristics of the moving load on the dynamic coefficient has been investigated. As a result, the dynamic stressed and strained state has been obtained as a multiplication of the static one with the dynamic coefficient. The developed approach has been compared with a finite element one for a concrete engineering case and thus its authenticity has been proved.

• 반도체디스플레이기술학회지
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• 제5권1호
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• pp.13-16
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• 2006

AIN thin films were prepared on amorphous glass and $SiO_2(1{\mu}m)/Si(100)$ substrate by the facing targets sputtering (FTS) apparatus, which can provide high density plasma, a high deposition rate at a low working gas pressure. The AIN thin films were deposited at a different nitrogen gas flow rate ($1.0{\sim}0.3$) and other sputtering parameters were fixed such as sputtering power of 200w, working pressures of 1mTorr and AIN thin film thickness of 800 nm, respectively. The thickness and crystallographic characteristics of AIN thin films as a function of $N_2$ gas flow rate $[N_2/(N_2+Ar)]$ were measured by $\alpha$-step and an X-ray diffraction (XRD) instrument. And the c-axis preferred orientations were evaluated by rocking curve. In the results, we could prepared the AIN thin film with c-axis preferred orientation of about $5^{\circ}$ on substrate temperature R.T. at nitrogen gas flow rate 0.7.

• International Journal of Reliability and Applications
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• 제10권2호
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• pp.89-99
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• 2009

Oriented Strand Board (OSB) is an important engineered wood product used in housing construction which has a lower environmental impact or "carbon footprint." In this paper, reliability and statistical tools are applied to gain insights on the strand thickness of OSB panels. An OSB panel consists of several hundred wood strands that are resinated and pressed. The variability of OSB strand thickness for six manufacturers in the Eastern United States is examined as a whole, as well as individually. Little research exists on OSB strand thickness across mills even though strand thickness variability has been documented in laboratory experiments to greatly influence the dimensional stability of OSB panels. Our aims are to quantify and characterize strand thickness, plus apply reliability techniques, such as Kaplan-Meier curves, to characterize the probability of strand thickness. We further explore graphically and statistically the thickness of the strands.

• The Korean Journal of Ecology
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• 제6권3호
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• pp.177-186
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• 1983

Vegetation types and their standing crop in the sand dune on the south coast of Korea was investigated by the method of Curtis, J.T. and McIntosh, R.P. (1951). The relationship between vegetation types and environmental factors was also analyzed. The dominant species in the vegetations of the south coast sand dune were Carex pumila, Calystegia soldamella, Imperata cylindrica var. koenigii, Vitex rotundifolia, Ixeris repens, Carex kobomugi, Zoysia macrostachya. The species density in the sand dune vegetation increased with the distance from the coast, psammophyte and rhizome psammophyte decreased with the distance from the coast but other plants increased. The standing crop of the sand dune vegetatiion was average $53.79g/m^2$. An individual standing crop of Vitex routundifolia and Carex kobomugi varied with the curve of secondary degree. The salt content of the sand dune soil from 2.95 to 11.78 mg %, and it was not significant differences among stands, but it was varied with the distance form the coast. Negative relationship between warmth index and aboveground standing crop was found and the formula y=283.8886 - 2.4910X could be estimated.