• Title/Summary/Keyword: R&D3.0

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Effects of xylooligosaccharide-sugar mixture on glycemic index (GI) and blood glucose response in healthy adults (자일로올리고당을 함유한 설탕이 건강한 성인의 Glycemic Index (GI)와 혈당에 미치는 효과)

  • Kyung, Myungok;Choe, HanSaem;Jung, Sangwon;Lee, Kyungsun;Jo, SungEun;Seo, Sheungwoo;Choe, Keunbum;Yang, Chang-Kun;Yoo, Sang-Ho;Kim, Yuri
    • Journal of Nutrition and Health
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    • v.47 no.4
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    • pp.229-235
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    • 2014
  • Purpose: The objective of this study was to investigate the effects of xyloologosaccharide (XOS)-sugar mixture on glycemic index (GI) and blood glucose in human subjects. Methods: Randomized double-blind cross-over studies were conducted to examine the effect of sucrose with 14% xyloologosaccharide powder (Xylo 14) and sucrose with 20% xylooligosaccharide powder (Xylo 20) on GI and postprandial glucose response at 15, 30, 45, 60, 90, and 120 min. Results: GIs of Xylo 14 and Xylo 20 were $60.0{\pm}23.5$ classified within medium GI range, and $54.3{\pm}17.7$ within low GI range, respectively. Xylo 14 and Xylo 20 showed significantly lower area under the glucose curve (AUC) for 0-15 min (p = 0.0113), 0-30 min (p = 0.0004), 0-45 min (p < 0.0001), 0-60 min (p < 0.0001), 0-90 min (p < 0.0001), and 0-120 min (p = 0.0001). In particular, compared with glucose, the blood glucose levels of Xylo 14 and Xylo 20 were significantly lower at every time point between 15 and 120 min. Conclusion: The results of this study suggested that Xylo 14 and Xylo 20 had an acute suppressive effect on GI and the postprandial glucose surge.

Relationships on Magnitude and Frequency of Freshwater Discharge and Rainfall in the Altered Yeongsan Estuary (영산강 하구의 방류와 강우의 규모 및 빈도 상관성 분석)

  • Rhew, Ho-Sang;Lee, Guan-Hong
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.16 no.4
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    • pp.223-237
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    • 2011
  • The intermittent freshwater discharge has an critical influence upon the biophysical environments and the ecosystems of the Yeongsan Estuary where the estuary dam altered the continuous mixing of saltwater and freshwater. Though freshwater discharge is controlled by human, the extreme events are mainly driven by the heavy rainfall in the river basin, and provide various impacts, depending on its magnitude and frequency. This research aims to evaluate the magnitude and frequency of extreme freshwater discharges, and to establish the magnitude-frequency relationships between basin-wide rainfall and freshwater inflow. Daily discharge and daily basin-averaged rainfall from Jan 1, 1997 to Aug 31, 2010 were used to determine the relations between discharge and rainfall. Consecutive daily discharges were grouped into independent events using well-defined event-separation algorithm. Partial duration series were extracted to obtain the proper probability distribution function for extreme discharges and corresponding rainfall events. Extreme discharge events over the threshold 133,656,000 $m^3$ count up to 46 for 13.7y years, following the Weibull distribution with k=1.4. The 3-day accumulated rain-falls which occurred one day before peak discharges (1day-before-3day -sum rainfall), are determined as a control variable for discharge, because their magnitude is best correlated with that of the extreme discharge events. The minimum value of the corresponding 1day-before-3day-sum rainfall, 50.98mm is initially set to a threshold for the selection of discharge-inducing rainfall cases. The number of 1day-before-3day-sum rainfall groups after selection, however, exceeds that of the extreme discharge events. The canonical discriminant analysis indicates that water level over target level (-1.35 m EL.) can be useful to divide the 1day-before-3day-sum rainfall groups into discharge-induced and non-discharge ones. It also shows that the newly-set threshold, 104mm, can just separate these two cases without errors. The magnitude-frequency relationships between rainfall and discharge are established with the newly-selected lday-before-3day-sum rainfalls: $D=1.111{\times}10^8+1.677{\times}10^6{\overline{r_{3day}}$, (${\overline{r_{3day}}{\geqq}104$, $R^2=0.459$), $T_d=1.326T^{0.683}_{r3}$, $T_d=0.117{\exp}[0.0155{\overline{r_{3day}}]$, where D is the quantity of discharge, ${\overline{r_{3day}}$ the 1day-before-3day-sum rainfall, $T_{r3}$ and $T_d$, are respectively return periods of 1day-before-3day-sum rainfall and freshwater discharge. These relations provide the framework to evaluate the effect of freshwater discharge on estuarine flow structure, water quality, responses of ecosystems from the perspective of magnitude and frequency.

Effect of R&D competence of Materials·Parts·Equipment Corporations on management performance

  • YU, Sun-Young;YOON, Sun-Jung;SEO, Jong-Hyen
    • The Journal of Economics, Marketing and Management
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    • v.10 no.3
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    • pp.1-8
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    • 2022
  • Purpose: This study aims to examine the effect of SMEs' R&D competence on management performance. Research design, data, and methodology: The empirical data of this study are derived from 2,375 SMEs that participated in the material, parts, and equipment research and development support project conducted from 2014 to 2018. Among them, 2,230 data were analyzed by classifying them into high-tech and low-tech fields. SPSS 24.0 was used for statistical analysis and correlation analysis and T-TEST were applied. Results: It was analyzed that the level of R&D organization, research personnel, and the number of patent registrations all affected operating profit and sales. In particular, it has been proven that research personnel have a greater impact on management performance among the level of R&D organization, research personnel, and the number of patent registrations. In addition, there was a difference between high-tech and low-tech industries in the impact on operating profit and sales, which are indicators of management performance. Conclusions: This study suggests that R&D competence are strengthened to advance the material, parts, and equipment industries and to promote future growth, while differentiated support is needed according to each company's R&D competence and technology level.

Protoplast Isolation and reversion from Pleurotus spodoleucus (참느타리버섯의 원형질체(原形質體) 분리(分離) 및 환원(還元))

  • Yoo, Young-Bok;Byun, Myung-Ok;Go, Seung-Joo;You, Chang-Hyun;Chang, Kwon-Yawl
    • The Korean Journal of Mycology
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    • v.15 no.1
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    • pp.19-22
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    • 1987
  • This experiment was undertaken to investigate proper conditions for protoplast formation from Pleurotus spodoleucus. Novozym 234 was the most effective enzyme and a high yield of protoplasts was obtained. Combination of enzymes did not improve this result. Sucrose gave the best result to support the release and maintain the stability of protoplasts. The optimal reaction time of mycelium with the lytic mixture was 3 hrs. in shaking condition at 120 strokes $min-^1$. When mycelium of P. spodoleucus was cultured for 3 days on mushroom complete agar medium at $27^{\circ}C$, the formation of protoplasts was effective. The mushroom complete agar medium stabilized with 0.6 M sucrose was the most effective for reversion of protoplasts.

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THERMAL-FLUID ANALYSIS FOR COOLING PERFORMANCE IMPROVEMENT OF 3.3KV(105A) COMPACT RACK TYPE MEDIUM VOLTAGE INVERTER SYSTEM (3.3kV(105A) COMPACT RACK TYPE 고압 인버터 시스템의 방열 성능 향상을 위한 열유동 해석)

  • Kim, S.Y.;Kim, S.D.;Ryoo, S.R.;You, N.K.;Kim, T.B.;Hong, C.O.;Ko, H.S.
    • Journal of computational fluids engineering
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    • v.19 no.3
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    • pp.24-28
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    • 2014
  • With ever rising concerns about saving of fossil fuel resource, there have been an increasing demand for use of energy more efficiently. The electric motor driven inverters can be a great help to improve energy efficiency. They are also used to control the motor speed to the actual need. Therefore the use of them can lead to reduce energy consumption. In particular, the medium voltage(MV) drive systems used for pumps, fans, steel rolling mills and tractions have widespread applications in the industry. They cover power ratings from 0.4MW to 40MW at the MV level of 2.3kV to 13.8kV. The majority of the installed MV drive systems however, are in the 1MW to 4MW range with voltage rating from 3.3kV to 6.6kV. But they are required to reduce size and weight like other power electronic equipments. In this paper, we studied on the 3.3kV(105A) compact rack type inverter system for improving the cooling efficiency. At first, we confirmed the tendency of temperature with computational simulation using ANSYS ICEPAK and actual experimental tests. And then we researched thermal performance improvement designs in order to reduce temperature of the transformer for the safe operation. It can reduce temperature of transformer that using pipe type flow guide in the system. As a result, we found out more efficient solution by thermal-fluid analysis.

Development of Superovulation Method in Korean Native Goats (한국 재래산양의 과배란 처치 방법 개선)

  • C. Y. Choi;D. S. Son;Y. K. Kim;M. H. Han;U. G. Kweon;S. H. Choi;Y. H. Choy;S. B. Choi;Y. M. Cho
    • Journal of Embryo Transfer
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    • v.19 no.1
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    • pp.61-66
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    • 2004
  • 한국 재래산양 체내수정란 생산에 대한 발정동기화 및 과배란 유도방법과 회수된 수정란의 동결 융해 후 생존율을 조사하였다. 발정동기화를 위해 CIDR+FSH 및 CIDR+PMSG의 방법을 이용한 결과, 배란점 및 회수된 수정란의 수는 CIDR+FSH 처리구에서 16.3개 및 9.4개, CIDR+PMSG 처리구에서 16.4개 및 8.7개를 나타내어 두 처리구간에 유의적 차이는 인정되지 않았다. 회수된 수정란을 형태학적으로 평가한 결과 CIDR+FSH 처리구에서 Gade A, B, C 및 D는 75.8%, 15.2%, 4.5% 및 4.5%를 나타낸 반면 CIDR+PMSG 처리구에서는 52.5%, 16.4%, 16.4% 및 14.8%였으며, 이식 가능한 수정란 (Grade A, B) 수는 CIDR+FSH 처리구가 유의적(P<0.05)으로 높게 나타났다. 회수된 수정란의 완만 동결 융해 후 생존성은 CIDR+FSH 처리구에서 73.3%, CIDR+PMSG 처리구에서 63.3%이었으며, 두 군간의 유의적차이는 인정되지 않았다. 따라서 본 결과는 한국 재래산양 체내수정란의 생산과 회수된 수정란의 보존을 위해서 CIDR+FSH로 발정동기화 시키는 것이 효과적이었다.

Choline and Betaine Concentrations in Breast Milk of Korean Lactating Women and the Choline and Betaine Intakes of Their Infants (한국 수유부 유즙의 콜린과 베타인 농도 및 영아의 콜린과 베타인 섭취량)

  • Jeong, Han-Ok;Suh, Yoon-Suk;Chung, Young-Jin
    • Journal of Nutrition and Health
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    • v.43 no.6
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    • pp.588-596
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    • 2010
  • Most nutrients taken by pregnant women are secreted into their breast milk. Food contains choline together with betaine, and in human body choline is oxidized to betaine which transfer methyl group. The aim of the study was to estimate the concentrations of choline and betaine in breast milk of Korean lactating women and the choline and betaine intakes of their infants. Total choline, free choline and betaine concentrations in breast milk of some lactating women living in Daejon Metropolitan city were analyzed every month by using HPLC-MS and enzymatic method during the first five months. Total choline concentrations of breast milks were 157.64 mg/L (1.52 mmol/L), 157.83 mg/L (1.52 mmol/L), 165.99 mg/L (1.60 mmol/L), 153.67 mg/L (1.48 mmol/L), 145.05 mg/L (1.39 mmol/L) by month after delivery for five months. The concentrations of total choline and free choline in breast milks were not significantly changed for the five months while the betaine concentrations gradually decreased. Daily intake of total choline of the infants appears to be adequate for the infant's requirement according to the US DRI; 124.6 mg/d, 120.9 mg/d, 126.5 mg/d 104.1 mg/d from 2nd to 5th month after birth. Free choline and betaine intakes of the infants were not significantly changed during the four months except showing decrease in betaine intake per kg body weight. Choline intakes of the infants more correlated with choline concentrations of the breast milks (r = 0.982, p = 0.000) than intake amount of the breast milk (r = 0.414, p = 0.028). These results suggest that the choline intake of Korean breast-fed infants appears to be adequate and the intake could be affected by the choline concentration of the breast milk.

Patterns of Nitrogen Excretion in Growing Pigs

  • Lee, K.U.;Boyd, R.D.;Austic, R.E.;Ross, D.A.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.6
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    • pp.732-738
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    • 1998
  • Three crossbred gilts weighing $61{\pm}2kg$ ($mean{\pm}SD$) and three gilts weighing $52{\pm}3kg $ on the day before the first treatment began (d -1) were used for each of two experiments (Exp. 1 and Exp. 2), respectively. In Exp. 1, all pigs were fed the experimental diet (CP 19%) from d -7 to the end of study (d 21) to verify that nitrogen retention is constant during the 21 -d period. In Exp. 2, pigs were fed the control diet (CP 15.5 %) from d -7 to d 8 and then the low-lysine diet from d 9 to d 16 in order to determine how rapidly dietary changes in amino acid composition results in a new equilibrium for nitrogen metabolism. The amount of urine nitrogen loss was not different over 21 days (p > 0.10). Rates of nitrogen retention were not different among pigs (p > 0.10) nor over time (p > 0.10). Average nitrogen retention during the period was 1.00 g/kg $BW^{0.75}$ per day. The apparent biological value was 41%, which did not change over the 3-week period (p > 0.10). The overall efficiency of nitrogen use for nitrogen retention was 35% (Exp. 1). The amount of nitrogen loss in urine and the efficiency of nitrogen utilization for nitrogen gain reached a new equilibrium within 2 to 3 d after the diet was changed. The low-lysine diet resulted in a 20% increase of nitrogen loss in urine (p < 0.001) and a 9% decline in efficiency of nitrogen use for nitrogen retention (p < 0.001). Nitrogen retention while the pigs were fed the control diet was also higher than the retention when pigs were fed the low lysine diet (p < 0.001). The efficiency of nitrogen use for nitrogen retention in pigs fed the control diet was 57% (Exp. 2), which was higher (p < 0.001) than that from pigs fed the low-lysine diets (52%).

EVALUATION FORMULAS FOR AN ANALOGUE OF CONDITIONAL ANALYTIC FEYNMAN INTEGRALS OVER A FUNCTION SPACE

  • Cho, Dong-Hyun
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.3
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    • pp.655-672
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    • 2011
  • Let $C^r$[0,t] be the function space of the vector-valued continuous paths x : [0,t] ${\rightarrow}$ $R^r$ and define $X_t$ : $C^r$[0,t] ${\rightarrow}$ $R^{(n+1)r}$ and $Y_t$ : $C^r$[0,t] ${\rightarrow}$ $R^{nr}$ by $X_t(x)$ = (x($t_0$), x($t_1$), ..., x($t_{n-1}$), x($t_n$)) and $Y_t$(x) = (x($t_0$), x($t_1$), ..., x($t_{n-1}$)), respectively, where 0 = $t_0$ < $t_1$ < ... < $t_n$ = t. In the present paper, with the conditioning functions $X_t$ and $Y_t$, we introduce two simple formulas for the conditional expectations over $C^r$[0,t], an analogue of the r-dimensional Wiener space. We establish evaluation formulas for the analogues of the analytic Wiener and Feynman integrals for the function $G(x)=\exp{{\int}_0^t{\theta}(s,x(s))d{\eta}(s)}{\psi}(x(t))$, where ${\theta}(s,{\cdot})$ and are the Fourier-Stieltjes transforms of the complex Borel measures on ${\mathbb{R}}^r$. Using the simple formulas, we evaluate the analogues of the conditional analytic Wiener and Feynman integrals of the functional G.

An 8b 220 MS/s 0.25 um CMOS Pipeline ADC with On-Chip RC-Filter Based Voltage References (온-칩 RC 필터 기반의 기준전압을 사용하는 8b 220 MS/s 0.25 um CMOS 파이프라인 A/D 변환기)

  • 이명진;배현희;배우진;조영재;이승훈;김영록
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.10
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    • pp.69-75
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    • 2004
  • This work proposes an 8b 220 MS/s 230 mW 3-stage pipeline CMOS ADC with on-chip filers for temperature- and power- insensitive voltage references. The proposed RC low-pass filters improve switching noise performance and reduce reference settling time at heavy R & C loads without conventional off-chip large bypass capacitors. The prototype ABC fabricated in a 0.25 um CMOS occupies the active die area of 2.25 $\textrm{mm}^2$ and shows the measured DNL and INL of maximum 0.43 LSB and 0.82 LSB, respectively. The ADC maintains the SNDR of 43 dB and 41 dB up to the 110 MHz input at 200 MS/s and 220 MS/s, respectively, while the SNDR at the 500 MHz input is degraded as much as only 3 dB than the SNDR at the 110 MHz input.