• Title/Summary/Keyword: R&D Productivity

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Treatment of Acid Mine Drainage using Eggshells and Microalgae (폐난각과 미세조류를 이용한 산성광산배수처리)

  • Choi, Hee-Jeong
    • Journal of Korean Society on Water Environment
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    • v.30 no.6
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    • pp.647-652
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    • 2014
  • The aim of this study was to investigate the heavy metal removal and biomass productivity in the Acid Mine Drainage (AMD) using eggshell and microalgae. The experiment was operated 6 days in the eggshell and microalgae hybrid system, and using eggshell powder and microalgae as Chlorella vulgaris. The obtained result indicated that the biomass productivity of 2.82 g/L/d from 1.12 g/L initial concentration in 6 days was reached with light transmittance of 97% at a 305 mm depth in the optical panel photobioreactor (OPPBR). The total removal efficiency of Fe, Cu, Zn, Mn and Cd was found to be 98.92%, 99.91%, 98.78%, 88.99% and 98.00% in the AMD using eggshell and Chlorella vulgaris hybrid system, respectively. Additionally, there were significant relationships between biomass and concentration of each heavy metal ($R^2$ = 0.8771, 0.8643, 0.8669, 0.9134 and 0.6277 for Fe, Cu, Zn, Mn and Cd). These results indicated that the eggshell and microalgae hybrid system was highly effective for heavy metal removal when compared to the conventional biological process in the AMD. Therefore, the eggshell and microalgae hybrid system was effective for heavy metal removal and biomass productivity and can be applied to treat AMD in treatment plant.

High-pressure Air Impulse Technique for Rehabilitating Well and Its Application to a Riverbank Filtration Site in Korea

  • Jeon, Hang-Tak;Hamm, Se-Yeong;Cheong, Jae-Yeol;Han, Suk-Jong;Yun, Sul-Min
    • Journal of Environmental Science International
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    • v.28 no.10
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    • pp.887-898
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    • 2019
  • Rehabilitation work is required to increase well productivity, which decreases with the elapsed time of pumping owing to the clogging of the water well. Clogging causes not only a reduction in the well productivity but also a deterioration of the water quality. For unclogging and rehabilitating wells, several techniques are used such as brushing, air surging, surge blocks, and gas impulse. In this study, the high-pressure air impulse technique, which effectively and economically rehabilitates wells, was applied to a riverbank filtration site in Korea for the same objective. At most of the wells, the hydraulic parameters (transmissivity, storage coefficient, and specific capacity) were increased by the application of the high-pressure air impulse technique. The well loss change values also indicate an increase in the hydraulic parameters by the air impulse implementation. Thus, the high-pressure air impulse technique can be efficiently and economically applied to water and riverbank filtration wells for rehabilitating the decreased productivity.

Raceway Cultivation of Spirulina platensis Using Underground Water

  • Kim, Choong-Jae;Jung, Yun-Ho;Ko, So-Ra;Kim, Hong-Ik;Park, Yong-Ha;Oh, Hee-Mock
    • Journal of Microbiology and Biotechnology
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    • v.17 no.5
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    • pp.853-857
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    • 2007
  • The semi-outdoor cultivation of Spirulina platens is was attempted using an underground-water-based medium. Occurrence of contaminant organisms such as Chlorella sp. and Chlamydomonas sp. was not found from a microscopic observation and bacteria were not detected from denaturing gradient gel electrophoresis(DGGE) analysis of PCR-amplified 16S rDNA during the cultivation, owing to pH control and the high quality of the underground water. The mean productivity was high at $10.5g/m^2/d$ with a range of $4.2-12.3g/m^2/d$ despite the unfavorable weather conditions of the rainy season. The cultivated S. platens is included a normal protein content of 58.9%. Consequently, the underground water improved the biomass productivity and the biomass quality because of an abundant supplementation of natural minerals and through a contaminant-free culture.

A study on the Birefringence Measurement in Injection Molded Parts using R-G-B separation of white Light (백색광의 R-C-B 성분 분해에 의한 사출품내의 복굴절 측정법 개발)

  • Kim J. S.;Yoon K. H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2004.10a
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    • pp.290-293
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    • 2004
  • Recently, injection molded plastic optical products are widely used, because injection molding process has advantages of low cost and high productivity. However, there remains residual birefringence and residual stresses originated from flow history and differential cooling. The present study focused on developing a technique measuring birefringence in optical plastic parts using R-G-B separation of white light. The main idea of an analysis comes from the fact that more information can be obtained from the distribution of retardation caused by different wavelengths. A complete system to give the quantitative values of retardation covering high order 2-D birefringence will be demonstrated. Further investigation is under way to improve the accuracy of the system using diodes as light sources.

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Development of Recombinant Chinese Hamster Ovary Cell Lines Producing Human Thrombopoietin or Its Analog

  • Chung, Joo-Young;Ahn, Hae-Kyung;Lim, Seung-Wook;Sung, Yun-Hee;Koh, Yeo-Wook;Park, Seung-Kook;Lee, Gyun-Min
    • Journal of Microbiology and Biotechnology
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    • v.13 no.5
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    • pp.759-766
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    • 2003
  • Recombinant Chinese hamster ovary (rCHO) cell lines expressing a high level of human thrombopoietin (hTPO) or its analog, TPO33r, were obtained by transfecting expression vectors into dihydrofolate reductase-deficient (dhfr) CHO cells and subsequent gene amplification in media containing stepwise increments in methotrexate (MTX) level such as 20, 80, and 320 nM. The parental clones with a hTPO expression level $>0.40\;{\mu}g/ml$ (27 out of 1,200 clones) and the parental clones with a TPO33r expression level $>0.20\;{\mu}g/ml$ (36 out of 400 clones) were subjected to 20 nM MTX. The clones that displayed an increased expression level at 20 nM MTX were subjected to stepwise increasing levels of MTX such as 80 and 320 nM. When subjected to 320 nM MTX, most clones did not display an increased expression level, since the detrimental effect of gene amplification on growth reduction outweighed its beneficial effect of specific TPO productivity ($q_{TPO}$) enhancement at 320 nM MTX. Accordingly, the highest producer subclones ($1-434-80^{*}$ for hTPO and $2-3-80^{*}$ for TPO33r), whose $q_{TPO}$ was 2- to 3-fold higher than that of their parental clones selected at 80 nM MTX, were isolated by limiting dilution method and were established as rCHO cel1 lines. The $q_{TPO}$ of $1-434-80^{*}\;and\;2-3-80^{*}\;was\;5.89{\pm}074\;and\;1.02{\pm}0.23\;{\mu}g/10^6$ cells/day, respectively. Southern and Northern blot analyses showed that the enhanced $q_{TPO}$ of established rCHO cell lines resulted mainly from the increased TPO gene copy number and subsequent increased TPO mRNA level. The hTPO and TPO33r produced from the established rCHO cell lines were biologically active in vivo, as demonstrated by their ability to elevate platelet counts in treated mice.

사업 포트폴리오의 기술시너지 효과 : 50대 재벌의 패널자료분석

  • 김태유;박경민
    • Journal of Technology Innovation
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    • v.5 no.1
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    • pp.15-43
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    • 1997
  • This paper investigates empirically the relationship between various business portfolio properties (particularly technological properties) and chaebol's performance using data on the 50largest chaebols in Korea. In addition to the traditional indexes to measure diversification such as entropy index, we calculated inter-industry technological similarity using R'||'&'||'D expenditure data by industry and 1990 Input-output Table in korea, and obtained chaebol-level technological relatedness and internal transaction proportion from chaebols' business profile, inter-inustry technological similarity and 1990 input-output table. We applied factor analysis on 13 business portfolio property indexes and showed that they could be grouped into 3 dimensions. diversification scope, inter-business relatedness and degree of vertical integration. In this paper, using 50 largest chaebols' financial data (1989-1994), we analyzed empirically the effect of business portfolio properties on ROS(Return On Sales) which is conventional index for firm performance and on TFP(Total Factor Productivity) growth which is a pure measure of firm performance. To utilize the advantage of panel data, FEM(Fixed Effect Model) and REM(Random Effect Model) were used. The empirical result shows that the entropy index as a measurement of inter-business relatedness in not significant but technological relatedness index is significant. OLS estimates on pooled data were considerably different from FEM or REM estimates on panel data. By introducing interaction effect among the three variables for business portfolio properties, we obtained three findings. First, only VI(Vertical integration) has a significant positive correlation with ROS. Second, when using TFP growth as an dependent variable, both TR(Technological Relatedness) and VI are significant and positively related to the dependent variable. Third, the interaction term between TR and VI is significant and negatively affects TFP growth, meaning that TR and VI are substitutes. These results suggest strategic directions on restructuring business portfolio. As VI is increased, chaebols will get more profit. A higher level of either TR or VI will increase TFP growth rate, but increase in both TR and VI will have a negative effect on TFP growth. To summarize, certain business portfolio properties such as VI and TR can be considered "resources" themselves since they can affect profit rate and productivity growth. VI and TR have a synergy effect of change in profit rate and productivity growth. VI increases ROS and productivity growth, while TR increases productivity growth representing a technological synergy effect.t.

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The Effect of Foreign Direct Investment on Total Factor Productivity in Selected ASEAN+3 Countries: New Evidence Using A Panel ARDL Study

  • ABIDIN, Noorazeela Zainol;KARIM, Zulkefly Abdul;SHAARI, Mohd Shahidan;LAILA, Nisful
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.10
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    • pp.109-117
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    • 2021
  • This study investigates the effects of FDI and other macroeconomic variables on Total Factor Productivity (TFP) in selected ASEAN+3 countries from 1981 till 2016. Total Factor Productivity (TFP) for each ASEAN+3 country was constructed using the Malmquist productivity index method. Then, a panel ARDL framework (dynamic heterogeneous panel), namely Pooled Mean Group (PMG), Mean Group (MG), and Dynamic Fixed Effect (DFE) are employed in examining the effects of FDI and other controlling variables on TFP. The new findings show that FDI has a significant and positive impact on TFP in the long run and the short run in ASEAN+3 countries. Besides, the results also reveal that in the long run, other variables such as the average number of years of schooling and the ratio of high-skilled to low-skilled labor also have a significant and positive effect on TFP. However, economic openness, government expenditure on R&D, and interaction between countries and FDI have a negative and significant impact on TFP. These findings implied that the recipient countries must ensure their political stability and offer various incentives to attract more investors. Furthermore, the influx of foreign investors, especially large ones and lower costs, should be encouraged by each country as FDI inflows can boost their TFP growth.

Selection of Pleurotus sajor-caju as Suitable Species for Cultivation under Summer Climatic Conditions in Korea (하기(夏期) 재배(栽培)에 알맞는 여름 느타리 버섯의 선발(選拔))

  • Go, Seung-Joo;Byun, Myung-Ok;You, Chang-Hyun;Park, Yong-Hwan
    • The Korean Journal of Mycology
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    • v.12 no.2
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    • pp.53-58
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    • 1984
  • This experiment was performed to select the most suitable species of oyster mush­room for cultivation during summer season in Korea. The selection was made based upon mycelial growth on the ricestraw substrates, fruiting under hot weather conditions during the summer season in Korea and potential high productivity using six cultures from South-east Asia. The newly selected strain of Pleurotus sajor-caju (ASI 2070) grew well on the rice straw substrates and produced the higher yields of sporophores than other cultures tested. The primordia of the mushroom were formed between 10 to $35^{\circ}C$. The optimal temperature for fruiting ranged from 20 to $25^{\circ}C$.

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Detection of Polyhydroxyalkanoate-Accumulating Bacteria from Domestic Wastewater Treatment Plant Using Highly Sensitive PCR Primers

  • Huang, Yu-Tzu;Chen, Pi-Ling;Semblante, Galilee Uy;You, Sheng-Jie
    • Journal of Microbiology and Biotechnology
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    • v.22 no.8
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    • pp.1141-1147
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    • 2012
  • Polyhydroxyalkanoate (PHA) is a class of biodegradable plastics that have great potential applications in the near future. In this study, the micro-biodiversity and productivity of PHA-accumulating bacteria in activated sludge from a domestic wastewater treatment plant were investigated. A previously reported primer set and a self-designed primer set (phaCF1BO/phaCR2BO) were both used to amplify the PHA synthase (phaC) gene of isolated colonies. The new primers demonstrated higher sensitivity for phaC, and combining the PCR results of the two primer sets was able to widen the range of detected genera and raise the sensitivity to nearly 90%. Results showed that 85.3% of the identified bacteria were Gram-negative, with Ralstonia as the dominant genus, and 14.7% were Gram-positive. In addition, Zoogloea and Rhizobium contained the highest amounts of intracellular PHA. It is apparent that glucose was a better carbon source than pentone or tryptone for promoting PHA production in Micrococcus. Two different classes, class I and class II, of phaC were detected from alphaproteobacteria, betaproteobacteria, and gammaproteobacteria, indicating the wide diversity of PHA-accumulating bacteria in this particular sampling site. Simultaneous wastewater treatment and PHA production is promising by adopting the high PHA-accumulating bacteria isolated from activated sludge.

A study on the success factors of ICT Convergence type-specific start-up enterprise - mainly the case study - (ICT융합 유형별 스타트업 기업의 성공요인에 관한 연구 -사례연구를 중심으로-)

  • Lee, Seo Han;Noh, Seung Hoon
    • Journal of Digital Convergence
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    • v.12 no.12
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    • pp.203-215
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    • 2014
  • Although many studies about start-up existed, It is almost never shown study about ICT convergence start-up enterprise. This study tries to analyze success factor to start-up enterprise in rapidly growing ICT convergence area. Based on 10 entrepreneurial success cases, We figure out the total 29 units success factors utilizing ERIS model. We classify ICT commercialization with 4 types which are software-R&D centric, software marketing centric, software plus hardware R&D centric, software plus hardware marketing centric. Among success factors the most success factor is related entrepreneur;s ability and include major and professional knowledge about ICT's filed, insight through sensitivity about technical paradigm etc. It was derived the success factors indicated in the course of commercialization of ICT Covergence Unlike other forms of the existing start-up entrepreneurs and contributed to typified in four forms startups for ICT Covergence start-up entrepreneurs.