Development of Recombinant Chinese Hamster Ovary Cell Lines Producing Human Thrombopoietin or Its Analog |
Chung, Joo-Young
(Department of Biological Sciences, Korea Advanced Institute of Science and Technology, R&D Center, Daewoong Co. Ltd.)
Ahn, Hae-Kyung (R&D Center, Daewoong Co. Ltd.) Lim, Seung-Wook (R&D Center, Daewoong Co. Ltd.) Sung, Yun-Hee (Department of Biological Sciences, Korea Advanced Institute of Science and Technology) Koh, Yeo-Wook (R&D Center, Daewoong Co. Ltd.) Park, Seung-Kook (R&D Center, Daewoong Co. Ltd.) Lee, Gyun-Min (Department of Biological Sciences, Korea Advanced Institute of Science and Technology) |
1 |
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
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DOI |
2 |
Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: Stability in the absence of selective pressure
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DOI ScienceOn |
3 |
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
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DOI |
4 |
Development and characterization of novel erythropoiesis stimulating protein (NESP)
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DOI ScienceOn |
5 |
Native thrombopoietin: Structure and function
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DOI ScienceOn |
6 |
Cell death (apoptosis) in cell culture systems
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DOI ScienceOn |
7 |
Effect of amplification of dhfr and lacZ genes on growth and β-galactosidase expression in suspension cultures of recombinant DHO cells
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DOI |
8 |
N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems
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DOI ScienceOn |
9 |
Production of monoclonal antibody using free-suspended and immobilized hybridoma cells: Effect of serum
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DOI |
10 |
Effect of cloned gene dosage on cell growth and Hepatitis B surface antigen synthesis and secretion in recombinant CHO cells
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DOI |
11 |
Integration, amplification and stability of plasmid sequences in CHO cell cultures
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DOI ScienceOn |
12 |
Getting the glycosylation right: Implications for the biotechnology industry
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DOI ScienceOn |
13 |
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
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DOI ScienceOn |
14 |
Peptide, disulfide and glycosylation mapping of recombinant human thrombopoietin from ser1 to Arg246
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DOI ScienceOn |
15 |
Analysis of foreign protein overproduction in recombinant CHO cells. Effect of growth kinetics and cell cycle traverse
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DOI ScienceOn |
16 |
Thrombocytopenia in c-mpl-deficient mice
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DOI |
17 |
Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure
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DOI ScienceOn |
18 |
Expression, purification and characterization of human recombinant thrombopoietin in Chinese hamster ovary cells
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DOI ScienceOn |
19 |
High level expression of the humanized monoclonal antibody Campath-1H in chinese hamster ovary cells
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DOI ScienceOn |
20 |
High-level production of recombinant proteins in CHO cells using a dicistronic DHFR intron expression vector
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DOI ScienceOn |
21 |
Screening of high-productivity cell lines and investigation of their physiology in Chinese hamster ovary (CHO) cell cultures for transforming growth factor-beta 1 production
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과학기술학회마을 |
22 |
Morphological selection of parental Chinese hamster ovary cell clones exhibiting high-level expression of recombinant protein
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23 |
Coamplification and coexpression of human tissue-type plasminogen activator and murine dihydrofolate reductase sequences in Chinese hamster ovary cells
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24 |
Key determinants in the occurrence of clonal variation in humanized antibody expression of CHO cells during dihydrofolate reductase mediated gene amplification
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DOI ScienceOn |
25 |
Overexpression of recombinant human antithrombin III in Chinese hamster ovary cells results in malformation and decreased secretion of recombinant protein
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DOI ScienceOn |
26 |
Enhancement of tissue type plasminogen activator(tPA) production from recombinant CHO cells by low electromagnetic fields
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과학기술학회마을 |
27 |
c-Mpl ligand is a humoral regulator of megakaryocytopoiesis
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DOI ScienceOn |
28 |
Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
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DOI ScienceOn |
29 |
Thrombopoietin and the humoral regulation of thrombocytopoiesis
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DOI ScienceOn |