• Clinical and Experimental Pediatrics
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• v.54 no.1
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• pp.22-28
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• 2011

Purpose: To investigate the clinical characteristics of late-onset epilepsy combined with autism spectrum disorder (ASD), and the relationship between certain types of electroencephalography (EEG) abnormalities in ASD and associated neuropsychological problems. Methods: Thirty patients diagnosed with ASD in early childhood and later developed clinical seizures were reviewed retrospectively. First, the clinical characteristics, language and behavioral regression, and EEG findings of these late-onset epilepsy patients with ASD were investigated. The patients were then classified into 2 groups according to the severity of the EEG abnormalities in the background rhythm and paroxysmal discharges. In the severe group, EEG showed persistent asymmetry, slow and disorganized background rhythms, and continuous sharp and slow waves during slow sleep (CSWS). Results: Between the two groups, there was no statistically significant difference in mean age (P=0.259), age of epilepsy diagnosis (P=0.237), associated family history (P=0.074), and positive abnormal magnetic resonance image (MRI) findings (P=0.084). The severe EEG group tended to have more neuropsychological problems (P=0.074). The severe group statistically showed more electrographic seizures in EEG (P=0.000). Rett syndrome was correlated with more severe EEG abnormalities (P=0.002). Although formal cognitive function tests were not performed, the parents reported an improvement in neuropsychological function on the follow up checkup according to a parent's questionnaire. Conclusion: Although some ASD patients with late-onset epilepsy showed severe EEG abnormalities, including CSWS, they generally showed an improvement in EEG and clinical symptoms in the longterm follow up. In addition, severe EEG abnormalities tended to be related to the neuropsychological function.

• The Journal of Korean Physical Therapy
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• v.14 no.3
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• pp.273-296
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• 2002

This study was conducted to investigate the pain relief score and the degree of satisfaction among elderly people. This study has done from July 11th, 2001 to August 31st, 2001 at Hydrotherapy Facility in the College of Bogun(Taejon Health Sciences College) located in Taejeon, Korea. Eighty-eight patients were participated to the questionnaire. The results were as follow. 1. The mean value of the pain relief score in the female group was higher than the mean value of the pain relief score in the male group(p<0.05). The mean value of the pain relief score in the group having religion was higher than the group not having religion(p<0.05). The pain relief score was not significantly different in age, presence of spouse, the way of housing, and academic background. The degree of satisfaction was not significantly different in sex, age, presence of spouse, the way of housing, religion, and academic background. 2. The pain relief score and the degree of satisfaction were not significantly different in the presence of comorbidity, going with the hydrotherapy, and the moment of diagnosis. 3. According to the ADL, the mean value of the pain relief score in the Independent was higher than the mean value in maximal assistance and minimal assistance(p<0.05). Independent, maximal assistance and minimal assistance were not significantly different in the degree of satisfaction (p<0.05). 4. The pain relief score and the degree of satisfaction were not significantly different in the legion of pain.

• The Journal of Korean Physical Therapy
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• v.10 no.2
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• pp.105-111
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• 1998

My prior questionnaire has applied to 12 male and 29 female adults over 30-69 years old suffering from lumbago fer 6 months at least or having diagnosis of lumbago. I had the following conclusions from physical characteristics and cardiopulmonary capacity of lumbago Patients caused by obesity 1) The rate of lipids in the body was rotated to the maximum heart rate in the male group of lumbago patients (P<0.01). 2) The rate of lipids in the body was related to the maximum intake of oxygen(O2) in the male group of lumbago patients(P<0.01). 3) The maximum heart rae was related to the maximum intake of oxygen in the male group of lumbago patients(P<0.01). 4) The rate of lipids in the body was related to the maximum intake of oxygen in the female group of lumbago patients(P<0.05). 5) The rate of lipids in the body showed no relation to the maximum heart rate in the female group of lumbago patients(P>0.05). 6) The maximum heart rate was related to the maximum intake of oxygen in the female group of lumbago patients(P<0.01). 7) The cardiovascular system showed no relation te the function of the lungs in the male and female groups of lumbago patients(P>0.05) 8) The lung capacity per second of lumbago patients(FEV $1.0\%$) measured less than normal adults. 9) The maximum intake of oxygen(V02max) and heart rate was less than normal adults. Thus I summarized the conclusion so follows: the cardiovascular system of lumbago patients showed no relation to their pulmonary function, and the rate of lipids in the body Showed a correlation with the maximum intake of oxygen but the rate of lipids in the body showed no relation to their pulmonary function.

• Journal of muscle and joint health
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• v.8 no.2
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• pp.250-261
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• 2001

Alternative therapy for rheumatoid arthritis has become worldwide phenomenon this decade without scientific validation. This study was undertaken to explore the prevalence, patterns of use, and perceived efficacy of alternative therapies by patients attending a rheumatology clinic. We conducted a crossectional survey of 142 RA patients with structured questionnaire at outpatient rheumatic clinic from July to August in 2001. Results of this study were summarized as follows : 1. 85.9% of subjects were woman. Mean age was 49.97years, duration of rheumatoid arthritis was 5.6years. Mean pain score was 5.29cm. 2. 74.6% of subjects perceived rheumatoid arthritis as a controllable disease. 31% of patients combined medical treatments with alternative therapies. 58.5% of patients perceived that combining medical treatments with alternative therapies is the most effective strategy in controlling disease. 3. 77.5% had used more than one alternative therapy since the diagnosis was made. The major reason of discontinuation of use was no effect for the treatment of their disease. 4. 34.5% were currently using an alternative therapies and 50.9% were going to use alternative therapies in future. 5. 42.7% reported that alternative therapies was effective and only 3.6% reported side effects. 6. The perceived effect score was 3.14cm in general expecially the physiological score 2.91cm, psychological score 4.16cm. In conclusion, our results demonstrate a high use of alternative therapies by rheumatoid arthritis patients. And the perceived effect score of physiological aspect was not higher than one of psychological aspect. Therefore it should be considered in education program for the use of alternative therapies.

• The Journal of Korean Physical Therapy
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• v.23 no.2
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• pp.69-76
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• 2011

Purpose: The aim of this study was to investigate the prevalence of depressive symptoms in stroke patients and to compare characteristics of different rating scales - Hamilton Depression Rating Scale (HDRS), Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale-Depression (HAD.D)- with regard to diagnosis and severity assessment for post-stroke depression. Methods: Participants included 44 stroke patients who could communicate. At admission, all study participants received a semi-structured interview using the HDRS and a self-completed questionnaire using the BDI and the HAD-D. Pearson's correlation method was used to examine associations among the three depression scales. The BDI and HAD-D were compared based on HDRS criteria, and the sensitivity and specificity using cut-off values were analyzed. Results: The HDRS showed that 52.30% of stroke patients had depressive symptoms on the BDI and HAD-D it was 59.10%. The HDRS correlated significantly with the BDI (r=0.81, p<0.01) and HAD-D (r=0.55, p<0.01). The BDI correlated significantly with HADS (r=0.50, p<0.01). After calculating the area under the ROC curve to decide on HDRS criteria, the BDI (AUC=0.91, 95% CI: 0.83.0.99) showed a significantly larger area compared to the HAD.D (AUC=0.82, 95% CI: 0.69-0.94). The cut-off value of the BDI was 12.50 points with a sensitivity of 81.00% and a specificity of 76.20%. Conclusion: These findings show that the BDI is a useful screening test for depression that most closely predicts the HRDS score.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2110-2116
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• 2012

This research focused on the strategy formulation for the development of the innovation cluster in Gyeonggi Province - 'Pankyo & Gwanggyo Technovalley'. The study was performed based on both theoretical study and quantitative & qualitative study approaches. Particularly, questionnaire survey was used for the diagnosis of the developmental stages of the innovation clusters. The major determinants for the development of the innovation cluster in Gyeonggi Province can be summarized as follows; the establishment of S&T based host institution, the gradual enlargement of the role of host institution and the enhancement of the network capability of innovation clusters. In terms of the needs of times, this study regarding the strategy for the development of the innovation clusters is anticipated to be a good reference for the R&D organizations and technology cluster participants in coming years.

• Journal of Periodontal and Implant Science
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• v.43 no.2
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• pp.96-100
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• 2013

Purpose: Chronic periodontitis (CP) seems to be associated with stress and depression, but little information on this possible association is available in the literature. Thus, the objective of this study was to evaluate the association among stress, the salivary cortisol level (SCL), and CP. Methods: Seventy systemically healthy subjects were included in the study from January to September 2011. Full medical and dental histories were obtained, and the following measurements were recorded: 1) probing depth; 2) clinical attachment level; 3) bleeding on probing; and 4) tooth mobility. Saliva samples were collected for the evaluation of SCL (via a highly sensitive electrochemiluminescence immunoassay), and all subjects also answered a questionnaire (i.e., the Zung Self-rating Depression Scale). The odds ratio (OR) with a 95% confidence interval (CI) was calculated, and one way analysis of variance and the Tukey-Kramer method were performed. Results: A total of 36 subjects with CP (51.4%) and 34 without CP were evaluated. Of them, all of the subjects with CP and one periodontally healthy subject were diagnosed with depression. Subjects with moderate CP had statistically significantly higher levels of SCL than subjects with a diagnosis of slight CP (P=0.006). Also, subjects with severe CP showed the same outcome when compared to those with slight CP (P=0.012). In addition, 46 subjects presented high SCL whereas 24 had a normal level. CP was found to be correlated with the SCL, with an OR of 4.14 (95% CI, 1.43 to 12.01). Conclusions: Subjects with a high SCL and depression may show an increased risk for CP.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.3
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• pp.156-172
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• 2010

Purpose: In Oriental medicine, menstruation is a significant index of women's health. Especially high school girls often have various menstrual problems. We think that students who have menstrual problem have some symptoms in relation to an etiological cause. So we had carried out this study to investigate association of DSOM scores and an abnormality of menstruation in oriental medicine. Methods: First we have 2137 high school girls answer to menstrual questionnaire that we made and DSOM, next investigated the pathogenic factor of DSOM which effect dysmenorrhea and menorrhagia using regression model. Logistic regression analysis indicate as follows. Results: 1. In comparison with dysmenorrhea, Qi depression(氣滯), blood stasis(血瘀), dampness (濕), phlegm(痰) is associated positively and liver(肝) negatively. The sensitivity is 64.3%, and the specificity is 75.1%. 2. In comparison with menorrhagia, Blood deficiency(血虛), Qi depression(氣滯), blood stasis(血瘀) is associated positively and liver(肝) negatively. The sensitivity is 53.9%, and the specificity is 76.1%. Conclusion: In this study, that has been carried out to organize the diagnosis of dysmenorrhea and menorrhagia in Oriental medicine, we can see that the disease factors of them were correlated with our Medical theory.

• Journal of Sasang Constitutional Medicine
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• v.21 no.1
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• pp.227-236
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• 2009

1. Objectives As a basic trial for identification of Sasang constitutional gene marker, we genotyped and analysed statistical relationships of STR(short tandem repeat) alleles and its distribution in each constitution. 2. Methods After obtaining basic constitutional data with questionnaire (QSCC II), decision of constitution was made by 3 different constitution specialists' diagnosis, and only the samples of specialists' agreement of each constitution by discussion were taken into this research. Using multiplex PCR kit, total 146 constitutional samples were amplified in 16 autosomal STR marker, genotyped, and analysed statistically. Among 16 markers, 15 were analysed in this study excluding the amelogenin marker is used for in gender identification. 3. Results and Conclusions It is difficult to determine the relationship between constitution and STR marker as the sample size is small, however, Penta D and vWA were shown to be related statistically with constitution. It has been know that STRs has no genetic informations, however there are some recent research results showing STRs as a regulatory element, relationship between microsatellite instability and repeat number and size, and post-transcriptional sigualing. STRs which is not known about its function currently, are proposed to have function and/or regulatory activities anyhow with Sasang constitution. It is believed that the results of this study can halp determine and deatify the markers related to Sasang Constitutional Medicien.

• Journal of Sasang Constitutional Medicine
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• v.29 no.2
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• pp.95-103
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• 2017

Objectives This study was aimed to analyze characteristics of facial shapes in adult women by sasang constitution using hyungsang classification. Methods Using a digital camera, we took a picture of 1,011 women who participated in clinical study on menstrual pain and acquired their 3D facial images with a face-only scanner. They filled out SSCQ-P(sasang constitution questionnaire for patient) for the diagnosis of sasang constitution. Based on the above photographs and 3D images, one of the hyungsang medicine specialist diagnosed according to five diagnostic criteria. The sasang constitution was diagnosed by referring to questionnaires and photographs. Frequency analysis was performed using the statistical analysis system version 9.4 and chi-square test was performed for validity evaluation. Results In taeeumin, the wide face shape(n=261, 74.36%) was much more than the narrow shape(n=90, 25.64%) and the convex face profile(n=164, 85.86%) was much more than the concave profile(n=27, 14.14%). Regardless of sasang constitution, angular face shape(n=501, 50%) was the most, followed by oval shape(n=317, 31.64%). Subjects with big ears(n=291, 29.19%) were the most, while big eyes(n=104, 10.43%) were the least. Subjects with eyes and nose tip upward(n=615, 78.05%) were the most, while eyes and nose tip downward(n=22, 2.79%) were the least. Conclusions Most Korean adult women have angular face, such as square or diamond, with slanted eyes and upturned nose. Taeeumin women have wide facial shape and convex profile.