• Journal of Ginseng Research
• /
• 제41권3호
• /
• pp.290-297
• /
• 2017

Background: The use of X-ray phase-contrast microtomography for the investigation of Chinese medicinal materials is advantageous for its nondestructive, in situ, and three-dimensional quantitative imaging properties. Methods: The X-ray phase-contrast microtomography quantitative imaging method was used to investigate the microstructure of ginseng, and the phase-retrieval method is also employed to process the experimental data. Four different ginseng samples were collected and investigated; these were classified according to their species, production area, and sample growth pattern. Results: The quantitative internal characteristic microstructures of ginseng were extracted successfully. The size and position distributions of the calcium oxalate cluster crystals (COCCs), important secondary metabolites that accumulate in ginseng, are revealed by the three-dimensional quantitative imaging method. The volume and amount of the COCCs in different species of the ginseng are obtained by a quantitative analysis of the three-dimensional microstructures, which shows obvious difference among the four species of ginseng. Conclusion: This study is the first to provide evidence of the distribution characteristics of COCCs to identify four types of ginseng, with regard to species authentication and age identification, by X-ray phase-contrast microtomography quantitative imaging. This method is also expected to reveal important relationships between COCCs and the occurrence of the effective medicinal components of ginseng.

• 한국정보통신학회논문지
• /
• 제23권1호
• /
• pp.7-12
• /
• 2019

정부지원 R&D 사업을 수행하는 기업들은 사업계획서 상에 정량적 평가지표를 제안하고 있다. 그러나 많은 기업들은 정량적 평가지표를 선정하는데 어려움을 겪고 있고 잘못된 평가지표의 선정으로 정량적 결과 도출이 어려운 경우도 있다. 본 논문에서는 기업들이 선정한 정량적 평가지표를 소프트웨어 품질을 정량적으로 측정할 수 있는 ISO/IEC 25023표준에 접목하여 그 경향을 분석한다. 먼저 분석 대상 데이터에 대한 수집방법과 공인시험기관에서 시험한 제품에 대해 산업분야별로 분류하고 기업에서 선정한 정량적 평가지표를 ISO/IEC 25023 표준의 8가지 품질특성별로 분석한다. 다음으로 ISO/IEC 25023 표준의 8가지 품질특성으로 분류한 정량적 평가지표에 대한 분석 결과를 바탕으로 기업들의 주로 선정하는 정량적 평가지표의 품질특성의 경향을 파악하고자 한다. 이를 통해 소프트웨어 제품의 품질을 평가할 수 있는 정량적 평가지표 선정에 도움이 될 것으로 기대된다.

• Safe Food
• /
• 제6권4호
• /
• pp.17-22
• /
• 2011

• 경영정보학연구
• /
• 제9권2호
• /
• pp.149-168
• /
• 2007

IT 투자성과의 정량화에 대한 필요성이 높아짐에 따라 학계와 연구단체에서 IT 투자성과의 화폐가치 전환 및 정량적 평가를 위한 다양한 측정방법들을 개발하여 제시하고 있으며, 이들 기법을 활용하여 IT 투자성과를 정량적으로 평가하는 기업들이 점차 늘고 있다. 그러나 이와 같은 IT 투자성과의 정량적 평가 기법을 도입한 기업의 실무자들은 화폐가치로 전환되어 도출된 결과들이 가시적으로 확인될 수 있는 것이 아니기 때문에 IT가 제공하는 실 효과를 제대로 반영하여 평가되었는지에 대하여 확신하지 못하고 있다. 이에 본 연구는 IT 투자성과의 정량적 평가 결과를 기존의 많은 연구를 통해 IT 투자성과의 정성적인 평가로 입증된 사용자 만족도로써 설명이 가능한지 파악하여 보기 위하여 기업의 사례 분석을 통해 그 상관관계를 분석하였다. 사례 연구 결과, 다음과 같은 시사점을 도출하였다. 첫째, 정보화 효과금액은 사용자 만족도와 상관관계가 있다. 둘째, 합리적인 정보화 효과금액의 도출을 위해서는 조직 내에서 시스템의 효과를 정량화할 수 있는 지표 개발 및 화폐전환 데이터의 관리가 중요하다. 셋째, IT ROI는 시스템 간의 성과를 비교하는 것에는 부적절하며 개별 시스템의 성과 및 효율성 측정 기준으로 사용하는 것이 적절하다. 넷째, 정량적 평가가 여전히 시스템의 전략적인 부분 등에 대한 평가에는 미흡하기 때문에 이를 보완하기 위한 방법으로 사용자 만족도를 함께 사용하는 것이 바람직하다.

• Korean Journal of Radiology
• /
• 제21권8호
• /
• pp.998-1006
• /
• 2020

Objective: To compare the accuracies of quantitative computed tomography (CT) parameters and semiquantitative visual score in evaluating clinical classification of severity of coronavirus disease (COVID-19). Materials and Methods: We retrospectively enrolled 187 patients with COVID-19 treated at Tongji Hospital of Tongji Medical College from February 15, 2020, to February 29, 2020. Demographic data, imaging characteristics, and clinical data were collected, and based on the clinical classification of severity, patients were divided into groups 1 (mild) and 2 (severe/critical). A semiquantitative visual score was used to estimate the lesion extent. A three-dimensional slicer was used to precisely quantify the volume and CT value of the lung and lesions. Correlation coefficients of the quantitative CT parameters, semiquantitative visual score, and clinical classification were calculated using Spearman's correlation. A receiver operating characteristic curve was used to compare the accuracies of quantitative and semi-quantitative methods. Results: There were 59 patients in group 1 and 128 patients in group 2. The mean age and sex distribution of the two groups were not significantly different. The lesions were primarily located in the subpleural area. Compared to group 1, group 2 had larger values for all volume-dependent parameters (p < 0.001). The percentage of lesions had the strongest correlation with disease severity with a correlation coefficient of 0.495. In comparison, the correlation coefficient of semiquantitative score was 0.349. To classify the severity of COVID-19, area under the curve of the percentage of lesions was the highest (0.807; 95% confidence interval, 0.744-0.861: p < 0.001) and that of the quantitative CT parameters was significantly higher than that of the semiquantitative visual score (p = 0.001). Conclusion: The classification accuracy of quantitative CT parameters was significantly superior to that of semiquantitative visual score in terms of evaluating the severity of COVID-19.

• 치과방사선
• /
• 제29권2호
• /
• pp.397-405
• /
• 1999

Purpose: To clarify the usefulness and the limitation of Digora system/sup (R)/ by evaluating the physical characteristics as the quantitative image on Image Plate(Ip). Materials and Methods: Radiograms were taken by Heliodent MD(Siemens Co.. Germany) with the image plate for adult. Cu-step wedge as reference material. and three pieces of dry mandibular bone. Image analysis was performed by single color enhancement. density measurement with histogram. The relationship between the exposure conditions and the distribution of the pixel values of the image. the variation of pixel values of each step of Cu-step wedge at two different area and Cu-equivalent value of three pieces of dry mandibular bone measure by the conversion equation. Results: There was no linear relationship between the exposure condition and the average pixel value of the image. of which the distribution was not even. The pixel value differences between the center portion and the periphery were ranged from 60 to 70 in vertical plane and from 15 to 26 in horizontal plane. Two plot profile formed at two different areas of the Cu-step wedge were different. The measured Cu-equivalent values showed the discrepancy among the times of measurement. Conclusion: As above results. Image Plate(Ip) of Digora system/sup (R)/ showed the limitation as the quantitative image. The physical property of IP was expected to need to be compensated for the quantitative evaluation of the bone or others

• Toxicological Research
• /
• 제34권4호
• /
• pp.303-310
• /
• 2018

The methods of applied genetic toxicology are changing from qualitative hazard identification to quantitative risk assessment. Recently, quantitative analysis with point of departure (PoD) metrics and benchmark dose (BMD) modeling have been applied to in vitro genotoxicity data. Two software packages are commonly used for BMD analysis. In previous studies, we performed quantitative dose-response analysis by using the PROAST software to quantitatively evaluate the mutagenicity of four piperidine nitroxides with various substituent groups on the 4-position of the piperidine ring and six cigarette whole smoke solutions (WSSs) prepared by bubbling machine-generated whole smoke. In the present study, we reanalyzed the obtained genotoxicity data by using the EPA's BMD software (BMDS) to evaluate the inter-platform quantitative agreement of the estimates of genotoxic potency. We calculated the BMDs for 10%, 50%, and 100% (i.e., a two-fold increase), and 200% increases over the concurrent vehicle controls to achieve better discrimination of the dose-responses, along with their BMDLs (the lower 95% confidence interval of the BMD) and BMDUs (the upper 95% confidence interval of the BMD). The BMD values and rankings estimated in this study by using the EPA's BMDS were reasonably similar to those calculated in our previous studies by using PROAST. These results indicated that both software packages were suitable for dose-response analysis using the mouse lymphoma assay and that the BMD modeling results from these software packages produced comparable rank orders of the mutagenic potency.

• Natural Product Sciences
• /
• 제17권4호
• /
• pp.321-327
• /
• 2011

In this study, quantitative analysis was developed using HPLC/UVD for the quality evaluation of Scutellariae Radix. For quantitative analysis, six major bioactive compounds were assessed. The separation conditions employed for HPLC/UVD were optimized using Phenomenex $C_{18}$ column ($250{\times}4.6$ mm, 5 ${\mu}m$) with a gradient of solvent A (1% acetic acid of $H_2O$) and solvent B (acetonitrile : methanol : acetic acid = 70 : 30 : 1) as the mobile phase at a flow rate of 1.0 mL/min and a detection wavelength of 275 nm. These methods were fully validated with respect to linearity, accuracy, precision and recovery. The HPLC/UVD method was applied successfully to the quantification of six major compounds in the extract of Scutellariae Radix. The results indicate that the established HPLC/UVD method is suitable for the quantitative analysis and quality control of multicomponents in Scutellariae Radix.

• 대한조현병학회지
• /
• 제23권1호
• /
• pp.15-28
• /
• 2020

Objectives: This study investigated the relationship between clock-drawing test (CDT) performance and neuropsychological functions in patients with chronic schizophrenia. Methods: Thirty-one patients with schizophrenia and 30 healthy controls participated in this study. The CDT was administered in three conditions and analyzed using both quantitative and qualitative scoring systems. Comprehensive neuropsychological tests were administered. Results: The results of the quantitative analysis showed that the schizophrenia group performed significantly worse in all three conditions of the CDT compared with the control group. However, no significant differences were observed between the two groups, when the IQ and educational level were controlled. The qualitative analysis showed that the schizophrenia group exhibited significantly more errors in "graphic difficulty" compared with the control group. In addition, CDT quantitative scores were significantly correlated with visuospatial function, memory, attention and executive functions in patients with schizophrenia. Conversely, each qualitative error type was correlated with specific cognitive domains. Furthermore, "graphic difficulty" and "spatial/planning deficit" were identified as predictors of depression symptoms in patients with schizophrenia. Conclusion: The present study demonstrated that the CDT is useful for assessing cognitive dysfunctions in patients with schizophrenia, while qualitative analyses provide more specific information about cognitive deficits compared with quantitative analyses.

• 정보보호학회논문지
• /
• 제19권6호
• /
• pp.175-184
• /
• 2009

정보 자산 보안 관련 위험을 추정함에 있어 정성적인 방법과 정량적인 방법이 사용되고 있으나, 두 가지 방법 나름대로 장단점을 갖고 있다. 지나치게 서술적이고 추상적인 정성적 방법과 구체적이지만 자료의 부족으로 인한 정확한 계산이 어려운 정량적 방법의 한계를 어느 정도 극복한 절충된 방법의 개발이 요구된다고 하겠다. 본 논문은 절충의 방법으로서 퍼지 숫자를 이용하는 방법을 제시하고 분석의 예를 보였다. 퍼지 숫자를 이용함으로 자료의 부족함을 전문자의 의견이나 가능한 자료로 대체할 수 있고 위험을 구체적인 수치로 추정할 수 있음을 확인하였다. 가상의 시스템에 대하여 다양한 위협을 가정하여 모의실험을 하였고 시스템에 대한 예상 위험과 비예상 위험을 예측하는 방법을 구현하였다.