• Journal of Microbiology and Biotechnology
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• v.27 no.7
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• pp.1276-1280
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• 2017

The mcr-1 gene is a new "superbug" gene discoverd in China in 2016 that makes bacteria highly resistant to the last-resort class of antibiotics. The mcr-1 gene raised serious concern about its possible global dissemination and spread. Here, we report a potential anti-resistant strategy using the CRISPR/Cas9-mediated approach that can efficiently induce mcr-1 gene knockout in Escherichia coli. Our findings suggested that using the CRISPR/Cas9 system to knock out the resistance gene mcr-1 might be a potential anti-resistant strategy. Bovine myeloid antimicrobial peptide-27 could help deliver plasmid pCas::mcr targeting specific DNA sequences of the mcr-1 gene into microbial populations.

• Journal of Construction Engineering and Project Management
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• v.3 no.3
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• pp.42-48
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• 2013

Construction industry is considered as the most hazardous industry due to its unique nature. Safety and quality management are essential to control hazards and improve success in project implementation. This paper focuses on evaluating the crucial factors influencing safety and quality management in construction projects. In order to achieve this, the qualitative and quantitative approaches were used for data collection. The findings of this study reveal the crucial safety factors as management commitment, safety awareness of top management practices/ procedures/ reviews, and errors in judgement or carelessness. Project supervision, employee involvement/ altitude, and expertise knowledge/ training were considered as the crucial quality factors influencing safety and quality management. The study shows that safety and quality issues cannot be overlooked therefore proper implementation is paramount to achieve project success.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.27 no.2
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• pp.138-148
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• 2017

Objectives: Sleep quality is directly related to the health, quality of life and working capacity and is affected by age, gender, exercise, life habits. Gender dissimilarities in sleep quality are acknowledged. However, the gender difference in the quality of sleep in shift workers was not well known. Our aim was to study the less known gender differences in the quality of sleep of shift workers. Methods: 1,008 study subjects aged between 21 and 57 years among these, 637(525 male and 112 female workers) were daytime workers and 371(253 males and 118 female workers) were shift workers. Sleep quality was measured by self-report through the Pittsburg Sleep Quality Index(PSQI) and fatigue was measured by using the Chalder Fatigue Scale(CFS). All data was analyzed using SPSS version 19.0 program. The study was approved by the Institutional Review Board of the Occupational Safety and Health Research Institute. Results: Overall, sleep quality was found to be worse in shift workers than in daytime workers and in female than in male. Fatigue in shift female workers was significantly higher than in daytime female workers and shift male workers. In Spearman correlation analysis results, fatigue were significantly associated with gender, drink habit, regular exercise, working hours and sleep quality. With group male workers as the reference, the odds ratio(OR) for having a CFS was 2.115(${\beta}$ value=0.749, p<0.01), and subjective sleep quality, sleep latency, daytime dysfunction and PSQI were 1.541(${\beta}$ value=0.432, p<0.05), 2.297(${\beta}$ value=0.831, p<0.001), 1.798(${\beta}$ value=0.587, p<0.01) and 2.224(${\beta}$ value=0.799, p<0.01), respectively. Conclusions: Shift work played an important role in lowering the quality of sleep, and the effect was more pronounced in female workers than in male workers. Sleep quality was related to fatigue, especially sleep quality, sleep duration, sleep disturbances and daytime dysfunction were significantly related. Therefore, to improve fatigue and sleep quality of shift worker, it is necessary to improve healthy habits such as regular exercise, smoking cessation, and limited drinking. In particular, it is urgent to develop and implement a regular exercise program to reduce fatigue and improve the quality of sleep in workplace.

• Journal of the Korea Safety Management & Science
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• v.6 no.2
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• pp.91-101
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• 2004

Consumers require various quality characteristics including safety. The reduction of risk concerned on product safety becomes an urgent issue in leading companies. The strategy for customer satisfaction by choosing attractive quality characteristic is not enough for risk reduction in view of producer. This paper presents a method for choosing quality characteristics and risk characteristics by integrating QFD based on quality requirements and AHP based on safety requirements, also shows its application for complex equipment.

• Proceedings of the Safety Management and Science Conference
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• 2004.05a
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• pp.137-144
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• 2004

Consumers require various quality characteristics including safety. The reduction of risk concerned on product safety becomes urgent issue in leading companies. The strategy for customer satisfaction by choosing attractive quality characteristic is not enough for risk reduction in view of producer. This paper presents a method for choosing quality characteristics and risk characteristics by integrating QFD based on quality requirements and AHP based on safety requirements, also shows its application for complex equipment.

• Proceedings of the Safety Management and Science Conference
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• 2004.11a
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• pp.245-252
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• 2004

This paper presents a method for choosing quality characteristics to consider safety by integrating QFD based on quality requirements and AHP based on safety requirements, also shows resources allocation method to maximize customer satisfaction by ranking the index of technical importance to cost.

• Quality Improvement in Health Care
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• v.25 no.2
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• pp.2-15
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• 2019

Purpose: The purpose of this study is to provide basic data for the development of the most appropriate and effective educational materials for patients and their caregivers through the educational experiences of patient safety officer. Methods: This study is a qualitative analysis that involves using the focus group interview to understand the patient safety education experience of the patient safety officer. Results: The patient safety education experience of the patient safety officer is divided into four topics: (1) patient safety education content (2) patient safety education method (3) patient safety education status (4) activation and improvement of patient safety education. Additionally, the study incorporated twelve subtopics: (a) falls (b) speak up (c) patient safety campaign (d) patient safety rounding and a one on one training (e) education through medical staff (f) education using broadcast, video, post, among others (g) a lot of education in patient (h) patients not interested in patient safety education (i) patient safety education is less effective (j) human and medical expenses support (k) provision of standardized educational materials (l) patient safety culture for patient participation. Conclusions: This study indicate that education for patients and the caregivers should be inclusive and protective of stakeholders from the risks involved in patient safety events. The experience of patient safety officer is necessary for patient safety education for both patients and the caregivers since it is the source of basic data for the future development of patient safety education.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.4
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• pp.569-575
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• 2017

Objective: The objective of this research was to study the electrical properties and quality of frozen-thawed chicken breast meat and to investigate the relationship between these parameters at different times of frozen storage. Methods: Thawed samples of chicken breast muscles were evaluated after being kept in frozen storage at $-18^{\circ}C$ for different periods of time (1, 2, 3, 4, 5, 6, 7, and 8 months). Results: The results showed that water-holding capacity (WHC) and protein solubility decreased while thiobarbituric acid-reactive substances content increased with increasing storage time. The impedance module of samples decreased during 8-month frozen storage. Pearson correlation coefficients showed that the impedance change ratio (Q value) was significantly (p<0.05) related to pH, color, WHC, lipid oxidation and protein solubility, indicating a good relationship between the electrical properties and qualities of frozen-thawed chicken breast meat. Conclusion: Impedance measurement has a potential to assess the quality of frozen chicken meat combining with quality indices.

• International Journal of Safety
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• v.7 no.1
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• pp.39-43
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• 2008

With ever increasing number of citizen using subway stations everyday, safety, health and comfort of passengers and occupants (mostly metro personnel) have become important social issues. Considering the fact that various physical variables and pollutants such as particulate, VOCs and biological agents are closely related to indoor air quality (IAQ) which may cause health problems, a method of quantitative assessment using information-theoretic measure on such variables needs to be devised and implemented for comfort, health and safety of passengers and occupants in the subway station. A basic framework for assessing indoor air quality (for comfort and health) and safety in subway station is suggested. In particular, application of information-theoretic measure for the assessment of indoor air quality, comfort and safety in subway station is discussed. Some examples are presented as well.

• Proceedings of the Safety Management and Science Conference
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• 1999.11a
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• pp.53-72
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• 1999

IPQC system was introduced for the flight safety at the age of scientific safety management in the 1980s. In spite of performing this system, aircraft accidents caused by human factors, which were above 70% among all flight accident factors, have not been reduced. Accordingly, throughout this paper I analyzed the aircraft accident factors by means of a literature study and a pilot survey. Then, based on the notion of TQC(Total Quality Control), I hierarchically classified Individual Quality into Capacity Management, Safety Management, and General Management and did the low-ranked management factors as well. AHP (Analytic Hierarchy Process), one of the scientific management methods, was used for estimating the relative importance of Individual Quality Control factors and the heavy aircraft accident causes over the last 20 years were analyzed according to the flight ranks. Based on the comparative analysis of results derived above, an IPQC model as flight ranks is established. In short, according to this newly suggested model we can obtain the maximum flight safety with the preventive actions against aircraft accidents caused by human factors and by improving the operation effect under the reasonable pilot management.