• 제목/요약/키워드: Qualitative level

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Proteomic Approach to Aging Research

  • 김동수
    • 한국생명과학회:학술대회논문집
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    • 한국생명과학회 2000년도 제28회 학술심포지엄
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    • pp.9-10
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    • 2000
  • The aging process is multifactorial and results from the combined effects of inherited(genetic) and acquired factors including life style, food habits, physical activity, and diseases. That give rise to the various approaches in aging. We are trying to study biological changes with aging, In detail we are focused on gene and protein function accompanied by normal or abnormal aging process, especially our efforts are aimed at revealing the functional relationship of proteins in aging as a final product of gene. We expect that proteomic approach to the study of protein function involved in aging should give us variety of integrated data to understand biological changes of long lived lives, We have applied expression proteomics to rat liver bred in dietary restriction or in at libitum to elucidate the effects of food habit on aging. Expression proteomics shows us protein profile in a selected tissue or cells as a whole and gives us the information about protein expression level, posttranslational modification and degenerative modification of expressed proteins. Comparative analysis of young and old rat liver by two dimensional gels shows that gene expression of several proteins was down regulated in old rats and some protein expression level is increased with aging. Dietary restriction slows down these changes of gene expression and in some proteins there's no difference in protein expression level at same ages in comparison with rats bred in at libitum. About forty protein was identified by peptide mass fingerprint with MALDI-TOF and rest of the protein of interest is in the course of identification, Also we are trying to make mitochondrial and cytosolic proteom reference map. These suborganelle proteom map will gives us the information about low abundance proteins and cellular localization of proteins. Proteomics is a growing methodology to study biological system. High throughput qualitative and qualitative aspect of this approach will gives us large amount of integrated information and speed up our understanding about biological system

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Qualitative and quantitative evaluation of root injury risk potentially burdening insertion of miniscrew implants

  • Antoszewska, Joanna;Trzesniewska, Paulina;Kawala, Beata;Ludwig, Bjorn;Park, Hyo-Sang
    • 대한치과교정학회지
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    • 제41권2호
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    • pp.112-120
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    • 2011
  • Objective: Microscrew implants (MSls) offer many advantages, but some complications are known to occur during their insertion. One of the most commonly reported complications is root injury. Our aim was to identify factors associated with root injury and to evaluate their qualitative and quantitative values. Methods: Thirty-five orthodontists placed MSls (AbsoAnchor$AbsoAnchor^{(R)}$, Dentos Co. Ltd, Daegu, Korea) in the upper jaw of typodonts, labially between the second premolar and the first molar, in low and high vertical positions. Root contacts were counted, and distances between MSI apices and roots were measured. Fear level of the orthodontists was surveyed before and after the experiment. Wilcoxon's test, chi-square test, and Mann-Whitney test were used for statistical analysis. Results: Overall root contact rate of MSI insertion was 23.57%. The root contact rate was significantly higher in MSls inserted at $90^{\circ}$ (45.71%) than at $30^{\circ}$ (1.43%). The distance between the dental root and MSI also increased significantly in MSls inserted at $30^{\circ}$. Mean fear level before MSI insertion (4.6) significantly decreased after insertion (3.2); the causative factors were risk of injury to dental root and maxillary sinus or mandibular canal. Conclusions: Root injury is relatively rare, and oblique angulation reduces the risk of root and MSI contact.

미혼성인남녀의 섹슈얼리티 형성과정에 관한 질적 연구 (A Qualitative Study on the Formative Processes of Premarital Adult Sexuality)

  • 박수선
    • 가정과삶의질연구
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    • 제27권5호
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    • pp.147-166
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    • 2009
  • The purpose of this research was conducted to formative processes and to interpret premarital adult's sexuality meaning. The interviews have been executed based upon ethnography approach and method of interview in depth within the framework of the Weis's sexual script theory (1998) and parent-children relation. The interview in depth has been conducted with unmarried 7 males and 8 females inclusive of college students, total 15 persons who were born 1974-1980 and living in Seoul and nearby suburban areas. A period of interviews were carried out from September until December 2003. Each interview was executed for 2 to 4 hours apiece, and each person had 2 to 4 interviews during the period. The result of analysis of the sexuality scripts theory from three different views indicates that the female informants appeared to rationalize the fact that traditional concept of the chastity as defined by the socio-cultural level has been changed. It also indicated that there were very few sex educations in the society at large except for the public medias including the Internet. The interrelation level indicates that positive interaction with the opposite sex has affected them in the course of their building up desirable personal relationship in the society and uplifting their sense of self-esteem. The internal level of sexuality, it is much dependent on the extent of individual inner recognition of sexuality. The parent-children relation view of sexuality, the most influential factor for their communication on sexuality lies in the extent of their realization on how positively their parents recognize their children.

저소득층이 경험하는 행복의 맥락 (The Context of Happiness Low-Income Households Have Experienced)

  • 권지성
    • 한국사회복지학
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    • 제65권2호
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    • pp.53-78
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    • 2013
  • 이 연구의 목적은 저소득층이 경험하는 행복의 맥락을 이해하고자 하는 것이다. 이러한 목적을 달성하기 위해서, 이 연구에서는 질적 연구방법을 활용하였으며, 귀납적 접근을 통해 자료를 분석하였다. 구체적으로, 먼저 저소득층이 경험하는 행복의 맥락을 사례별로 살펴보았다. 개별 연구참여자들이 부여한 행복 점수와 그 의미, 주관적 경험들과 다양한 영역들로 구성된 현상을 분석하고, 그러한 행복과 경험, 현상으로 구성된 맥락 구조를 그려보았다. 사례들을 개별적으로, 그리고 연속적으로 분석하고 검토하고 연결하는 과정을 통해, 결과적으로 전체 사례들을 통합할 수 있는 맥락 구조가 구성되었다. 분석 결과, 연구참여자인 저소득층들이 인식하는 행복의 수준은 객관적인 상태보다는 주관적인 경험과 직접 관련되는 것으로 나타났다. 또한 이들의 주관적인 경험은 마음 안에서 작용하는 매우 복합적인 경험 요소들로 구성되어 있으며, 개인의 가치관에 의해 어떠한 경험요소들이 더 중요하게 평가되는가에 따라서 행복의 수준이 달라지는 것으로 나타났다. 이러한 연구결과에 근거하여, 저소득층의 행복수준을 향상시키기 위해 고려해야 할 정책과 실천 지침들을 제언하였다.

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사회적 지지가 농촌 조손가족 조모의 심리적 복지에 미치는 영향 (The Effect of the Social Support on the Psychological Well-being of Custodial Grandmothers in Rural Korea)

  • 이정화;최원규
    • 한국지역사회생활과학회지
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    • 제23권4호
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    • pp.419-439
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    • 2012
  • Family dissolution and economic difficulties of the grandchild's parents are the most prevailing reason for an increase of grandparent-headed families in rural Korea. However, there is a lack of empirical research looking at the experiences of custodial grandmothers, social support, and their psychological well-being. In this regard, this study examined the effect of social support (formal & informal) on the psychological well-being of custodial grandmothers in rural Korea. For this purpose, quantitative and qualitative research methods were conducted. Quantitative data were gathered, using structured questionnaire, from 311 grandmothers who were raising their grandchildren in rural Korea as primary care-givers. Statistical methods used for data analysis were descriptive statistics and hierarchical regression analysis with SPSS WIN 19.0 programs. Qualitative data were collected by in-depth interviews to 10 custodial grandmothers in rural area. The results of this study are as follows. First, almost half of the parents of the grandchild didn't visit and didn't call anymore. Some relatives -aunt, uncle, etc.- support the grandparent-headed family economically and emotionally. 3/4 of the grandparent-headed families were supported by the government and community. This was not small numbers, but the amount of economic support was low. Second, grandmothers in the study showed quite a high level of depression while their happiness level was relatively low. There were differences in the factors influencing the level of happiness/depression of these rural grandmothers. Overall, the study's results showed the importance of formal & informal support for psychological well-being of the custodial grandmothers in rural Korea. Policy and theoretical implications are discussed.

이중연료엔진의 연료가스공급시스템에 대한 안전무결도 기반 안전계장시스템 설계 (SIS Design for Fuel Gas Supply System of Dual Fuel Engine based on Safety Integrity Level(SIL))

  • 강낙원;박재홍;정정호;나성
    • 대한조선학회논문집
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    • 제49권6호
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    • pp.447-460
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    • 2012
  • In this study, the shutdown system of the fuel gas supply system is designed based on the Safety Integrity Level of IEC 61508 and IEC 61511. First of all, the individual risk($10^{-4}$/year) and the risk matrix which are the risk acceptance criteria are set up for the qualitative risk assessment such as the HAZOP study. The natural gas leakage at the gas supply pipe is identified as the highest risk among the hazards identified through the HAZOP study and as a safety instrumented function the shutdown function for leakage was defined. SIL 2 and PFD($2.5{\cdot}10^{-3}$) for the shutdown function are determined by the layer of protection analysis(LOPA). The shutdown system(SIS) carrying out the shutdown function(SIF) is verified and designed according to qualitative and quantitative requirements of IEC 61508 and IEC 61511. As a result of SIL verification and SIS conceptual design, the shutdown system is composed of two gas detectors voted 1oo2, one programmable logic solver, and two shutdown valve voted 1oo2.

회계서비스종사자 전문성과 회계정보시스템 수준이 고객사 회계정보의 질에 미치는 영향 (The Effects of Accounting Service Worker's Professionalism and Accounting Information System's Level on the Quality of Customer's Accounting Information)

  • 이지영;김경일
    • 중소기업융합학회논문지
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    • 제6권3호
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    • pp.1-6
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    • 2016
  • 이 연구의 목적은 회계서비스종사자의 전문성과 회계정보시스템 수준을 분석하여 고객사 회계정보의 질에 미치는 영향을 질적 특성을 중심으로 검증하는 것이다. 연구방법은 먼저 문헌에 의한 이론적 배경을 살펴본 후 설문에 의한 자료를 토대로 가설을 세우고 경험적 연구를 하였다. 그 결과 회계서비스종사자의 전문성을 필요로 하는 회계정보시스템으로 서비스를 제공받은 고객사는 질적 특성 중에서 충실한 표현에 가장 만족하는 것으로 나타났으며, 적시성이 가장 만족감이 낮은 것으로 나타났다. 본 연구는 회계서비스종사자의 전문성 인지와 향상에 기여할 것이며, 향후 회계정보의 질을 높이기 위한 회계서비스종사자의 교육과 훈련의 내용 및 방법에 대한 논의가 필요하다.

Predisposing, Enabling, and Reinforcing Factors of COVID-19 Prevention Behavior in Indonesia: A Mixed-methods Study

  • Putri Winda Lestari;Lina Agestika;Gusti Kumala Dewi
    • Journal of Preventive Medicine and Public Health
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    • 제56권1호
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    • pp.21-30
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    • 2023
  • Objectives: To prevent the spread of coronavirus disease 2019 (COVID-19), behaviors such as mask-wearing, social distancing, decreasing mobility, and avoiding crowds have been suggested, especially in high-risk countries such as Indonesia. Unfortunately, the level of compliance with those practices has been low. This study was conducted to determine the predisposing, enabling, and reinforcing factors of COVID-19 prevention behavior in Indonesia. Methods: This cross-sectional study used a mixed-methods approach. The participants were 264 adults from 21 provinces in Indonesia recruited through convenience sampling. Data were collected using a Google Form and in-depth interviews. Statistical analysis included univariate, bivariate, and multivariate logistic regression. Furthermore, qualitative data analysis was done through content analysis and qualitative data management using Atlas.ti software. Results: Overall, 44.32% of respondents were non-compliant with recommended COVID-19 prevention behaviors. In multivariate logistic regression analysis, low-to-medium education level, poor attitude, insufficient involvement of leaders, and insufficient regulation were also associated with decreased community compliance. Based on in-depth interviews with informants, the negligence of the Indonesian government in the initial stages of the COVID-19 pandemic may have contributed to the unpreparedness of the community to face the pandemic, as people were not aware of the importance of preventive practices. Conclusions: Education level is not the only factor influencing community compliance with recommended COVID-19 prevention behaviors. Changing attitudes through health promotion to increase public awareness and encouraging voluntary community participation through active risk communication are necessary. Regulations and role leaders are also required to improve COVID-19 prevention behavior.

Land Use, Land-Use Change and Forestry 매트릭스 작성을 위한 공간정보 특성 고찰 (Analysis of Spatial Information Characteristics for Establishing Land Use, Land-Use Change and Forestry Matrix)

  • 황진후;장래익;전성우
    • 한국지리정보학회지
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    • 제21권2호
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    • pp.44-55
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    • 2018
  • 기후변화에 대응하기 위한 정책 수립과 이행을 위해 온실가스 인벤토리 작성의 중요성이 대두되고 있다. 이에 따라, 토지이용 항목과 변화들에 대해 공간 명시적으로 나타낸 Approach 3 수준의 Land Use, Land-Use Change and Forestry(LULUCF) 매트릭스 구축 필요성이 제기되고 있다. 본 연구에서는 LULUCF 매트릭스의 산림 항목을 중심으로 연속지적도, 중분류 토지피복지도, 임상도, 도시생태현황지도를 활용하여 LULUCF 매트릭스 구축에 적합한 공간정보를 검토하였다. 각 공간정보에 대한 분류 속성 비교를 실시하였고 충청남도 보령시를 대상으로 양적(면적) 비교, 질적(특성) 비교를 실시하였다. 양적 비교 결과 산림의 면적이 임상도에서 최고 50.42%($303.79km^2$), 지적도에서 최저 46.09%($276.65km^2$)의 차이를 보였다. 질적 비교 결과 자료 구축 범위 차이, 자료 구축 목적 차이, 분류 항목 차이, 일필일목의 원칙 적용 여부의 차이, 자료구축 시기 차이 등 5가지 질적 특성의 차이를 확인하였다. 연구 결과 도시생태현황지도가 LULUCF 매트릭스 구축에 가장 적합한 공간 정보로 판단되었으나 전국구축이 되어있지 않은 한계로 토지피복지도가 가장 적합한 것으로 검토되었다. 또한, 도시생태현황지도, 임상도, 토지피복지도 등을 서로 종합하여 LULUCF 매트릭스를 구축하게 될 경우 각 공간정보의 한계를 보완할 수 있을 것으로 사료된다. 추후 전국토를 대상으로 하는 1:5,000 수준의 세분류 토지피복지도 및 도시생태현황지도가 완료될 경우 LULUCF 매트릭스 작성의 정밀도를 향상시킬 수 있을 것으로 판단된다.

논문 질적평가를 통한 KIGAM 세계수준 후보연구실 기술수준 평가 (Qualitative Analysis of Research Papers of KIGAM World Class Laboratories (WCL) Candidates)

  • 안은영
    • 자원환경지질
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    • 제47권3호
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    • pp.227-235
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    • 2014
  • 본 연구에서는 지질자원 분야 연구개발 수월성을 제시할 수 있는 평가방법인 계량서지학(Bibliometrics)의 SCI논문 분석을 통해 질적평가 지표를 제시하고, 이를 KIGAM의 6개 세계수준 후보 연구실의 기술수준 분석에 적용했다. Heo et al. (2008), Cho (2013)에서 제시되었던 표준화된 순위보정 영향력 지수(mrnIF)를 연구수월성 지표로 활용하였다. 2012년 편당 IF는 희유자원활용 분야 KIGAM 연구실이 가장 높았으나 순위(position) 지수 및 표준화된 순위보정 영향력 지수(mrnIF)는 지하수(최고순위 적용 position/mrnIF), 자원탐사개발(평균순위 적용 position/mrnIF) 분야가 제일 높게 나타났다. 시계열 분석 결과 표준화된 순위보정 영향력 지수(mrnIF)는 지하수 분야 연구실이 2009년, 2011년 실적이 월등이 좋으나 타년도의 경우 도시광산 및 자원탐사개발 분야 연구실이 우수한 실적을 보이는 것을 알 수 있다. 수월성 지표로 전체 게재논문 중 표준화된 순위보정 영향력 지수(mrnIF)가 80 이상인 비율 및 90 이상인 비율로 비교한 결과, 2011년의 경우 지하수 분야 연구실이 가장 우수하였으나 다른 연도의 경우 지표별로 다른 순위를 보여 가장 우수하다고 보기 어려웠다. Cho (2013)의 최고등급 연구수월성 지표인 90 이상 논문 비율 20% 이상을 도시광산 분야 연구실이 만족하고 있으며 지하수 분야 연구실은 평균순위를 적용한 2010년을 제외하고 만족하고 있었다. 이와 같이 양적인 논문 수 뿐 만 아니라 논문의 질적 분석을 통해 해당 연구실의 기술수준을 비교할 수 있었다. 세계 수준의 연구실이 되기 위해서는 양적인 SCI 논문 수의 확대 뿐 만 아니라 논문의 질적 향상을 위해 노력해야 할 것이다.