• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.1-13
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• 2016

Objectives : The purpose of this study is to compare hair and alopecia of Korean Medicine with those of western medicine. Methods : We studied relationships between hair and essense(精), qi(氣), blood(血), five vicera(五臟) and meridians(經絡) through literature review about hair and alopecia. We compared Korean medicine with western medicine on physiology of hair and treatment of alopecia based on the study. Results & Conclusion : 1. Congenital essense(先天之精) is related with genetic factor and acquired essence(後天之精) is connected with nutritional factor. Defending function of Defense qi(衛氣) is related with immune reaction and qi stagnation(氣鬱) is associated with stress reaction. Atrophy of vascular tissues observed in alopecia scalp means deep relationship between blood(血) and alopecia, further deficiency of blood can cause telogen effluvium. 2. Kidney qi(腎氣) is related with inhibiting combination of Androgen receptor and Dihydrotestosterone(DHT) or activating hair growth factior. Pi(脾) is connected with alopecia seborrheica caused by damp-heat(濕熱) and alopecia areata caused by excessive prudence(思慮過度). Heart(心) is associated with atrophy in vascular tissue of scalp and liver(肝) is connected with metabolism. 3. Armpit hair and pubic hair as secondary sex characteristics are realated with Yangming Meridian(陽明經) and beard and hair at crown part where Type II $5{\alpha}$-reductase is activated much are associated with Taiyang Meridian(太陽經). 4. Juglandis Semen pharmacopuncture and Ganoderma lucidum pharmacopucture have better effects on inhibit $5{\alpha}$-reductase than Finasteride. Minoxidil and PRP are similar with promoting blood flow and removing stasis(活血祛瘀). Seven-star needling(七星針) is similar with microneedling. 5. Alopecia can be caused by due to lack of circulation Views we need solution to improve circulation coincide in opinion with Korean Medicine and Western medicine.

• YAKHAK HOEJI
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• v.51 no.1
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• pp.13-34
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• 2007

Traditional Medicine (TM) is called as philosophical medicine in Korea. An unified theory named as Sihnsang-hanron (SSHR) was hypothesized through studies of scientific analyses on various theories of TM. SSHR has extracted seven concepts which are six common ones from the great three books (三大原典) and the Logic of Laotzu & Chuangtzu (老莊思想). Six common concepts are the affecting by cold (傷寒), qi (氣), cold or heat (寒熱), exterior & interior of body (表裏), deficiency or excessiveness (虛實), and yin & yang (陰陽). We have tried to apply these seven concepts to Physics and Life Science. The affecting by cold means anti-sunlight and the origin of all diseases. The difference between TM and modern medical science would be in diagnostic methods as well as their theoretical analyses for various diseases. The modern science follows Haeckel's positive dialectics applied by the biological monism, and oriental one(SSHR) does Yin-Yang monism from the studies of Logic of Laotzu (老子) & Chuangtzu (莊子). SSHR would make the theory of exterior & interior of body (表裏論) and six channels (六經) develope scientifically as a diagnostic technique of disease. This theory is an excellent one that can't be found out in modern medical science, and so it should be developed as a scientific theory by using modern mechanic instrument. Chuangtzu asserted that ai was the basic substance of the universe. It is hypothesized that qi (氣) is like small particles -higgs, with dynamic power in modern Physics. We consider cautiously qi could be calculated by mathematics through higgs' bosons in near future.

• Integrative Medicine Research
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• v.6 no.3
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• pp.317-324
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• 2017

Background: Bu-Zhong-Yi-Qi-Tang (BZYQT) has long been used for the treatment of severe weakness caused by general fatigue, loss of appetite, or indigestion. The aim of this feasibility study is to assess the effectiveness and safety of BZYQT for the treatment of functional dyspepsia (FD) with spleen qi deficiency. Methods: This study will be conducted at a single center as a prospective, nonrandomized, nonblinded, single-arm feasibility study. A total of 30 participants diagnosed with FD in accordance with the Rome III criteria will be enrolled. All patients will receive BZYQT for 4 weeks. The primary outcome is the change in the Nepean Dyspepsia Index-Korean version (NDI-K) scores between the baseline and 4-week images. The secondary outcomes include the tongue coating thickness, blood parameters, and BZYQT Questionnaire score. The NDI-K score will be acquired four times, at Weeks 0 (baseline), 2 (during treatment), 4 (after treatment), and 8 (after follow-up). Written informed consent will be obtained from all study participants prior to enrollment. This study has been approved by the Institutional Review Board of Kyung Hee University Korean Medicine Hospital. This study protocol is registered with the national clinical trial registry of the World Health Organization International Clinical Trials Registry Platform. Results will be published in a journal and will be disseminated both electronically and in print. Discussion: The results of this study may serve as a guide for researchers seeking to effectively evaluate the effects of BZYQT.

• Journal of Society of Preventive Korean Medicine
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• v.4 no.2
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• pp.170-192
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• 2000

Objectives : This study was carried out to research antioxidant effects of Sagunja-Tang(SA) through in vitro and vivo experiments, and tried to investigate the relation between oxidation of tissues and deficiency of Qi. Methods and results : HPLC analysis of glycyrrhizine - known to be the main compound of Radix Glycyrrhizae - was done to certify the quality of SA. Chemiluminescence was initiated by adding tort-butyl hydroperoxide (t-BHP) to rabbit polymorphonuclear leukocytes (neutrophils), and generated reactive oxygen species (superoxide anion) decreased significantly by SA as dose dependent manner. Cell injury during 60 minutes tissue incubation was initiated by adding t-BHP, a hydrophobic hydroperoxide and $H_2O_2$, an water soluble oxidant to rat renal cortical and liver slices. Percentage cell death and lipid peroxidation were estimated by measuring lactate dehydrogenase (LDH) and malondialdehyde (MDA), a product of lipid peroxidation. t-BHP induced % cell death of renal cortical slices and lipid peroxidation of renal cortical and liver slices were decreased significantly by SA. SA decreased significantly % cell death and lipid peroxidation of renal cortical and liver slices induced by $H_2O_2$, too. Acute renal and liver injury induced by $HgCl_2\;and\;CCl_4$, which initiated from free radical, were applied to mice and metabolic data were obtained. Data showed protective effects of SA on acute renal injury caused by decrease of glomerular filtration. SA protected acute liver injury too. Conclusions Through this study, we found that SA have antioxidant effects and tissue oxidation was similar to deficiency of Qi. And further studies have to be followed to certify the mechanisms.

• The Journal of Internal Korean Medicine
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• v.37 no.6
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• pp.998-1011
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• 2016

Objectives: This study measured the thickness of the abdominal wall at abdominal acupoints using ultrasonography and then investigated the correlations between the thickness of the abdominal wall and other characteristics of patients with functional dyspepsia (FD). Methods: Thirty patients with FD were enrolled in the study from September 2015 to March 2016. The thickness of the abdominal wall was measured at Shangwan (CV12), Zhongwan (CV13), and the left Liangmen (ST21). In addition, height, weight, body mass index (BMI), duration of FD, and the sternocostal angle were investigated. The severities of spleen qi deficiency and the dyspepsia symptoms were assessed by the Spleen Qi Deficiency Questionnaire (SQDQ) and the Nepean Dyspepsia Index-Korean version (NDI-K). Results: The average thickness of the abdominal wall was $24.66{\pm}6.69mm$ at Shangwan, $21.17{\pm}5.83mm$ at Zhongwan, and $21.72{\pm}5.72mm$ at Linagmen, and there were significant differences between the thickness at Shangwan and Zhongwan (p=0.046). Furthermore, there were significant differences between the thickness of the abdominal wall at Zhongwan and the sternocostal angle (r=0.396, p=0.037). Conclusions: These findings indicate the possibility of estimating the thickness of the abdominal wall by looking at the characteristics of patients with FD, including the sternocostal angle.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.361-369
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• 2015

Benign prostatic hyperplasia(BPH) is a common disease among male. However, its cause and treatment are not known and it is easy to relapse to the patients again after some treatment. Chinese has got an active research on BPH of traditional Chinese medicine. We researched the Chinese clinical papers from 2000 to 2014. After translating those papers, we analyzed total 45 papers by classifying those according to frequently used prescriptions, differentiation of symptoms, signs, addition and subtraction of each medicine and the quantity of frequently used medicines. Through this study it was to provide evidence in the diagnosis and treatment of BPH. The prescription of BPH was classified according to its stage. Mainly damp heat patterns(濕熱型) induce dysuria, Qi-stagnation and blood stasis patterns(氣滯血瘀型) induce pain, While Kidney deficiency patterns(腎虛型) induce sexual function disorder. This analysis report would be able to provide the basis of taking a research on BPH. In addition, it could be applied on a stereotype of BPH as well as a variety of symptoms with frequently used prescription and addition and subtraction of each medicine.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.2
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• pp.112-125
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• 2017

Objectives : The prevalence of allergic rhinitis (AR) is 10-40% worldwide and there are many demands for Traditionl Medicine (TM) treatment for AR. Pattern identification (PI) is essential process in diagnosis and treatment of TM, however, objective assessment measurement for PI of AR in TM is lacked. Methods : PI questionnaire for AR was developed in 2008 by specialists in the department of Otolaryngology of TM, based on systemic and nasal symptoms and signs. However, that questionnaire had many problems in application to clinical practice and has since been revised based on several studies and delphi method. Consequently, the PI questionnaire for AR version 3.0 has been developed. Results & Conclusions : This questionnaire classifies patients with AR as possessing lung-heat, lung-cold, or spleen qi deficiency based on nasal symptoms and general conditions of AR patients. This is first questionnaire for pattern identification of AR. We plan to conduct a validation and reliability study, and revise the questionnaire based on the results of this study.

• Korean Journal of Oriental Medicine
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• v.11 no.1
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• pp.127-138
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• 2005

We have examined the phase of Bian Zheng(辨證) by individual characteristics, who underwent the Oriental Medical Physical Examination, based on the Bian Zheng questionnaire of Korea Institute of Oriental Medicine. Since the correlations in all Bian Zhengs showed meaningful results at 0.01(p-value<0.05) in terms of level of significance and all coefficients are in positive value, the correlation in these Bian Zhengs could be said to exhibit the change toward the same direction with close correlation rather than contradictory change. The mean Bian Zheng score of women was generally higher than that of men, particularly in Blood-Deficiency, Qi-Stasis, Qi-Deficiency. But there is no difference of the mean Bian Zheng score in Sasang Constitution. We performed the Linear regression analysis to see the change of Bian Zheng score by age and could presume that the older they are, the higher Bian Zheng score, but statically the result is not meaningful. By the above result, we could come to the conclusion that the Bian Zhen questionnaire is more useful to the patient than the healthy people.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.4
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• pp.97-108
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• 2014

Objectives: This study is to report the clinical effect of oriental medicine on a patient suffering from postabortal syndrome with somatic pain disorder, Qi deficiency and depression. Methods: The patient had a miscarriage by cervical incompetence in 24 weeks' gestation even though she had operated cervical cerclage in 20 weeks' gestation. The patient received herbal medication, acupuncture, moxibustion during 20 days of outpatient treatment. The clinical effects were evaluated through VAS (Visual Analogue Scale) and EPDS (Edinburgh Postnatal Depression Scale Test). Results: The clinical symptoms of somatic pain and Qi deficiency were reduced during the treatment. The EPDS score also decreased from 19 points (high risk level) to 8 points (low risk level). Conclusions: This case study showed that herbal medicine, acupuncture and moxibustion treatment appeared to effectively reduce postabortal syndrome. Since patients previously experienced cervical incompetence tend to have habitual abortion for next pregnancy, further long term observation and preventive treatment are needed in this case for next safe pregnancy and childbirth.

• Korean Journal of Acupuncture
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• v.17 no.1
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• pp.123-140
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• 2000

The purpose of this study is to understand the special character and the tendency of the movement change that 12 meridians possess. We studied about the incidental and fundamental rule of the six atmospheric influence that was presented by Pyobonjoong(the incidental, fundamental, intermediate) theory, and the Hwang won-uh's the Six Channel activity of the Qi theory that presented movement form of the meridian through the six atmospheric influence. Then we found the following substances. The Pyobonjoong(the incidental, fundamental, intermediate) theory is applicable to understand the special character and the tendency of the movement change that Meridians possess. But, because the Pyobonjoong(the incidental, fundamental, intermediate) theory can't classify the characteristic difference of the hand and foot meridians, then the principle that can devide the meridians of the hand and foot, must be supplied. The Jungwha(right changing)-Daewha(opposite changing) theory is able to concretely classify the special character of the hand and foot six meridians. And Hwang's Shawha(superintending change)-Jongwha(following change) theory that is base on Jungwha(right changing)-Daewha(opposite changing) theory, is able to classify the special character of the hand and foot six meridians, too. If the concept of the Meridians is understood by the Shawha(superintending change)-Jongwha(following change) theory, the special character of the hand and foot six meridians could be concretely classified and then the meridian of the Bowels and the six atmospheric influence corresponded to the meridians could be expansively explained as the point that take charge and control these special Qi in the human body The Bon-Qi(fundamental Qi) act on the special character of Shawha(superintending change) six meridians and the tendency of the movement change is cause by the insufficiency and excessiveness of the Bon-Qi(fundamental Qi). The Qi of the Shawha(superintending change) meridians act on the special character of Jongwha(following change) six meridians and the tendency of the movement change is cause by the exuberance of Yang and the deficiency of Yang.