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Genetic Change from Colorectal Carcinoma Patients Using Comparative Genomic Hybridization (비교유전자교잡법을 이용한 대장암환자에서의 유전자변화)

  • Lee, Jae Sik
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.4
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    • pp.209-215
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    • 2015
  • Colorectal carcinoma is one of the four major cancers in Korea, and it shows the tendency of increase every year due to economic development and changes to western styles. Accordingly, various diagnostic methods are needed and so comparative genomic hybridization (CGH) was performed. Deletion was detected on 5q (10%), 10q (17%), 17p (40%), 18p (23%), 18q (47%), 22q (23%), and higher deletion loci were 18q (12/30, 47%), 17p (12/30, 40%), and 22q (7/30, 23%). Amplification was shown on chromosomes 6pq (10%), 7p (17%), 7q (33%), 8q (13%), 9pq (10%), 12q (17%), 13q (37%), 20p (23%), and 20q (57%) respectively. The highest amplification was detected on chromosomes 20q (17/30, 57%), 13q (11/30, 37%), and 7q (10/30, 33%). The genetic change pattern with the locus of colorectal carcinoma was shown mean 3.1 (amplification 1.7, deletion 1.4) on the right colorectal carcinoma, while rectal carcinoma appeared high mean 6.3 (amplification 3.7, deletion 2.6) (p<0.001). The genetic change pattern with lymphatic gland metastasis, mean 3.5 (amplification 2.2, deletion 1.3) from "no metastasis" group, while high mean 6.3 (amplification 3.5, deletion 2.8) from metastasis group (p<0.003). The genetic change pattern with disease stages appeared mean 3.5 (amplification 2.1, deletion 1.4) from I-II stages, while high mean 6.0 (amplification 3.4, deletion 2.6) from III-IV stages (p<0.006). No significance was observed in comparing histological classification and serum CEA increased groups.

A Study of the Relationships among RMR, Q-system and GSI Applied to Classify Rock Mass of Limestone Mine (석회석 광산의 암반 분류에 적용된 RMR, Q-system, GSI 간의 상관성 연구)

  • Yoon, Yong-Kyun;Lee, Hong-Woo
    • Explosives and Blasting
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    • v.35 no.4
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    • pp.27-35
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    • 2017
  • A total of 22 sites around openings of limestone mine are chosen to assess rock mass classification schemes such as RMR, Q-system, and GSI. RMR and Q are modified to estimate the relationship with GSI. Q' is the modified Q with SRF=1.0 and $J_w=1.0$. Rock mass is assumed to be completely dry and very favorable discontinuity orientations are assumed to estimate ${RMR_{89}}^{\prime}$. Relationships of Q-Basic RMR, Q-Total RMR, ${GSI-RMR_{89}}^{\prime}$, and GSI-Q' are analyzed, in which a correlation of ${GSI-RMR_{89}}^{\prime}$ is found to be the highest. Failure strains are calculated using the modulus ratios and most measuring sites appear to be stable with low failure strain class.

Seismic Wave Attenuation in the Southern Korean Peninsula: Separation of Intrinsic and Scattering Attenuations (한반도 남부에서의 지진파 감쇠: 고유감쇠와 산란감쇠의 분리)

  • Kim, Sung-Kyun
    • Journal of the Korean earth science society
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    • v.30 no.1
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    • pp.40-48
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    • 2009
  • The attenuation mechanism of seismic waves in the crust is controlled both by intrinsic absorption and scattering of energy. The amount of scattering and intrinsic energy losses from the total attenuation is separately estimated in this study for the southern Korean Peninsula. The formula to be deduced from the theoretical relationship between single back-scattered coda Q and multiple scattering theory was used to separate the total attenuation into the intrinsic Q and the scattering Q. It was found that the intrinsic Q was considerably lower than that of the scattering Q in the frequency range of 1.5 to 20 Hz. This fact implies that the energy loss caused by the intrinsic absorption is relatively larger than one by the scattering effect within the crust of the southern Korean Peninsula. Both intrinsic and scattering Q values appeared to be comparatively larger than those measured in other seismically active regions except for intrinsic Q in the frequency range of 1.5 to 3 Hz.

CHARACTERIZATION OF STRICTLY OPERATOR SEMI-STABLE DISTRIBUTIONS

  • Choi, Gyeong-Suk
    • Journal of the Korean Mathematical Society
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    • v.38 no.1
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    • pp.101-123
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    • 2001
  • For a linear operator Q from R(sup)d into R(sup)d and 0$\alpha$ and parameter b on the other. characterization of strictly (Q,b)-semi-stable distributions among (Q,b)-semi-stable distributions is made. Existence of (Q,b)-semi-stable distributions which are not translation of strictly (Q,b)-semi-stable distribution is discussed.

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A NOTE ON THE ZEROS OF THE q-BERNOULLI POLYNOMIALS

  • Ryoo, Cheon-Seoung
    • Journal of applied mathematics & informatics
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    • v.28 no.3_4
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    • pp.805-811
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    • 2010
  • It is the aim of this paper to observe an interesting phenomenon of 'scattering' of the zeros of the q-Bernoulli polynomials $B_{n,q}(x)$ for -1 < q < 0 in complex plane. Observe that the structure of the zeros of the Genocchi polynomials $G_n(x)$ resembles the structure of the zeros of the q-Bernoulli polynomials $B_{n,q}(x)$ as q $\rightarrow$ -1.

FINITE LOGARITHMIC ORDER SOLUTIONS OF LINEAR q-DIFFERENCE EQUATIONS

  • Wen, Zhi-Tao
    • Bulletin of the Korean Mathematical Society
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    • v.51 no.1
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    • pp.83-98
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    • 2014
  • During the last decade, several papers have focused on linear q-difference equations of the form ${\sum}^n_{j=0}a_j(z)f(q^jz)=a_{n+1}(z)$ with entire or meromorphic coefficients. A tool for studying these equations is a q-difference analogue of the lemma on the logarithmic derivative, valid for meromorphic functions of finite logarithmic order ${\rho}_{log}$. It is shown, under certain assumptions, that ${\rho}_{log}(f)$ = max${{\rho}_{log}(a_j)}$ + 1. Moreover, it is illustrated that a q-Casorati determinant plays a similar role in the theory of linear q-difference equations as a Wronskian determinant in the theory of linear differential equations. As a consequence of the main results, it follows that the q-gamma function and the q-exponential functions all have logarithmic order two.

Molecular Mapping of the Blast Resistance Loci in the Durable Resistance Japonica Rice Cultivar, Palgong (도열병 내구 저항성 자포니카 벼품종 팔공의 저항성 관련 유전좌위 분석)

  • Baek, Man-Kee;Cho, Young-Chan;Park, Hyun-Su;Jeong, Jong-Min;Kim, Woo-Jae;Nam, Jeong-Kwon;Kim, Choon-Song;Kwon, Soon-Wook;Kim, Bo-Kyeong
    • Korean Journal of Breeding Science
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    • v.51 no.4
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    • pp.395-403
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    • 2019
  • Rice blast caused by the fungus Magnaporthe grisea (anamorphic: Pyricularia oryzae) is an important disease in rice and development of resistant varieties to blast is one of the most important goals in rice breeding programs. A japonica rice variety, Palgong, has shown resistance to the Korean blast pathogen since it was developed in 1996. Nine blast resistance quantitative trait loci (QTLs) in Palgong alleles were identified on chromosomes 2, 4, 7, and 11. Four QTLs of qBn2.3, qBn4.2, qBn11.1, and qBn11.2 explained 28-56.7% of total phenotypic variation, while five QTLs of qBn2.2, qBn2.4, qBn4.1, qBn7.1, and qBn7.2 explained 9.7-18.8%. In a previous study, one to four resistance genes were located on the loci qBn2.2, qBn2.3, qBn4.2, qBn11.1, and qBn11.2, however, resistance genes were not located on the loci qBn2.4, qBn4.1, and qBn7.1. A major QTL, qBn11.2, explaining 56.7% of total phenotypic variation was related to the durable resistance of Palgong. Additionally, rice stripe virus resistance of Palgong was assumed to be based on the Stvb-i gene, which is located on a major QTL qBn11.2.

Carbon Stocks in Tree Biomass and Soils of Quercus acutissima, Q. mongolica, Q. serrata, and Q. variabilis stands (상수리나무, 신갈나무, 졸참나무, 굴참나무 임분의 임목 바이오매스와 토양 탄소 저장량)

  • Lee, Sang Tae;Chung, Sang Hoon;Kim, Choonsig
    • Journal of Korean Society of Forest Science
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    • v.111 no.3
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    • pp.365-373
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    • 2022
  • We compared carbon stocks in tree biomass and soils of Quercus acutissima, Q. mongolica, Q. serrata, and Q. variabilis stands. A total of 531 plots (Q. acutissima: 110 plots, Q. mongolica: 177 plots, Q. serrata: 96 plots, Q. variabilis: 148 plots) were examined between 2016 and 2021 to determine the tree biomass and soil carbon stocks throughout the country. The carbon stocks of tree biomass were significantly higher in Q. mongolica (mean stand age, 57 years, 144.9 Mg C ha-1) than in Q. variabilis (mean stand age, 43 years, 123.7 Mg C ha-1), Q. serrata (mean stand age, 43 years, 120.1 Mg C ha-1), and Q. acutissima (mean stand age, 36 years, 113.2 Mg C ha-1) stands. The soil carbon concentration was significantly higher in Q. mongolica (A: 43.1 mg C g-1) than in Q. serrata (31.0 mg C g-1), Q. variabilis (25.31 mg C g-1), and Q. acutissima (24.4 mg C g-1) stands. The soil carbon stocks were significantly higher in Q. mongolica (116.8 Mg C ha-1) than in Q. acutissima (49.3 Mg C ha-1) stands. Total carbon stocks of tree biomass and soil were highest in Q. mongolica (262 Mg C ha-1), followed by Q. serrata (218 Mg C ha-1), Q. variabilis (211 Mg C ha-1), and Q. acutissima (163 Mg C ha-1) stands. Multiple linear regressions were performed to estimate the total carbon stocks of the four Quercus spp., and results showed that total carbon stocks increased with increasing elevation, mean diameter at breast height, and basal areas. Basal area and elevation of Quercus spp. stands were important explanatory variables based on multiple linear regressions for estimating carbon stocks.

The Design and Implementation of Library for RTOS Q+ (실시간 운영체제 Q+를 위한 라이브러리 설계 및 구현)

  • Kim, Do-Hyeong;Park, Seung-Min
    • The KIPS Transactions:PartD
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    • v.9D no.1
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    • pp.153-160
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    • 2002
  • This paper describes the design and implementation of library for real-time operating system Q+, that was developed for the internet appliance. The library in the real-time operating system should be defined according to the standard interface and support the functions that are adequate to the real-time application. To ensure the compatibility between application programs, the Q+ library follows industrial and international standards, such as POSIX.1, ISO 7942 GKS. And, to support the Q+ application, library provides C standard functions, graphic/window functions, network functions, security support functions, file system functions. The Q+ library was implemented using the Q+ kernel, Digital TV set-top box, and KBUG debugging tool.

A GENERALIZATION OF MAYNARD'S RESULTS ON THE BRUN-TITCHMARSH THEOREM TO NUMBER FIELDS

  • Ahn, Jeoung-Hwan;Kwon, Soun-Hi
    • Journal of the Korean Mathematical Society
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    • v.59 no.5
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    • pp.843-867
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    • 2022
  • Maynard proved that there exists an effectively computable constant q1 such that if q ≥ q1, then $\frac{{\log}\;q}{\sqrt{q}{\phi}(q)}Li(x){\ll}{\pi}(x;\;q,\;m)<\frac{2}{{\phi}(q)}Li(x)$ for x ≥ q8. In this paper, we will show the following. Let 𝛿1 and 𝛿2 be positive constants with 0 < 𝛿1, 𝛿2 < 1 and 𝛿1 + 𝛿2 > 1. Assume that L ≠ ℚ is a number field. Then there exist effectively computable constants c0 and d1 such that for dL ≥ d1 and x ≥ exp (326n𝛿1L(log dL)1+𝛿2), we have $$\|{\pi}_C(x)-\frac{{\mid}C{\mid}}{{\mid}G{\mid}}Li(x)\|\;{\leq}\;\(1-c_0\frac{1og\;d_L}{d^{7.072}_L}\)\;\frac{{\mid}C{\mid}}{{\mid}G{\mid}}Li(x)$$.