• Title/Summary/Keyword: Q&A

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Concrete Mixture Design for RC Structures under Carbonation - Application of Genetic Algorithm Technique to Mixture Conditions (탄산화에 노출된 콘크리트 구조물의 배합설계에 대한 연구 - 유전자 알고리즘 적용성 평가)

  • Lee, Sung-Chil;Maria, Q. Feng;Kwon, Sung-Jun
    • Journal of the Korea Concrete Institute
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    • v.22 no.3
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    • pp.335-343
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    • 2010
  • Steel corrosion in reinforced concrete (RC) structures is a critical problem to structural safety and many researches are being actively conducted on developing methods to maintain the required performance of the RC structures during their intended service lives. In this study, concrete mixture proportioning technique through genetic algorithm (GA) for RC structures under carbonation, which is considered to be serious in underground site and big cities, is investigated. For this, mixture proportions and diffusion coefficients of $CO_2$ from the previous researches were analyzed and fitness function for $CO_2$ diffusion coefficient was derived through regression analysis. This function based on the 12 experimental results consisted of 5 variables including water-cement ratio (W/C), cement content, sand percentage, coarse aggregate content per unit volume of concrete in unit, and relative humidity. Through genetic algorithm (GA) technique, simulated mixture proportions were proposed for 3 cases of verification and they showed reasonable results with less than relative error of 10%. Finally, assuming intended service life, different exposure conditions, design parameters, intended $CO_2$ diffusion coefficients, and cement contents were determined and related mixture proportions were simulated. This proposed technique is capable of suggesting reasonable mix proportions and can be modified based on experimental data which consider various mixing components like mineral admixtures.

Phase Noise Analysis in the OFDM Communication System (OFDM 통신시스템에서 위상 잡음분석)

  • 이영선;유흥균;정영호;함영권
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.11
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    • pp.1043-1050
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    • 2004
  • In this paper, Phase noise is analyzed and a novel approach of the nonlinear approximation including second order term of phase noise is presented to analyze and quantize system performance. As results, in QPSK-OFDM system, when PLL loop bandwidth is 5.0 Hz, 1.0 kHB, 0.5 kHz respectively, there are about 0.6 dB, 1.0 dB, 1.7 dB SNR penalties at BER=10$\^$-4/ compared with system without phase noise in AWGN channel. In 16QAM modulation, there are about 1.9 dB, 3.2 dB, 6.7 dB SNR penalties at BER=10$\^$-4/ respectively. At QPSK-OFDM system, comparing the previous linear approximation method with our proposed nonlinear approximation method, there is similar BER performance at phase noise variance lower than 0.02, but certain difference occurs as variance increases more than 0.02. Furthermore, analytical BER results closely match with simulation results in the OFDM system employing QPSK and 16qAM modulation. And, BER performance of QPSK-OFDM system is considerably degraded because of the BER error floor if the phase noise variance becomes larger than 0.03.

The effect of chlorhexidine varnish application on the shear bond strength of orthodontic brackets (클로르헥시딘 바니쉬의 적용이 교정용 브라켓의 전단접착강도에 미치는 영향)

  • Im, Dong-Hyuk;Kim, Tae-Woo;Chang, Young-Il;Nahm, Dong-Suk;Yang, Won-Sik;Baek, Seung-Hak
    • The korean journal of orthodontics
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    • v.30 no.2 s.79
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    • pp.215-222
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    • 2000
  • The purpose of this study was to determine whether the application of chlorhexidine varnish affects the shear bond strength and failure pattern of orthodontic brackets or not. The experimental group consisted of 22 human premolars which extracted after chlorhexidine varnish application (4 times for 1 week interval) in vivo, and the control group consisted of 22 human premolars which extracted without any pre-treatment. After all teeth were etched with $37\%$ phosphoric acid gel, metal orthodontic brackets (Q-3002, RMO, USA) were bonded to each tooth using auto-polymerizing orthodontic resin (Ortho-One, Bisco, USA) with the same bonding procedure. The shear bond strength was measured with Instron universal testing machine (model 4466, Instron Ltd., England), and the failure pattern of each bracket was examined with Scanning Electron Microscope (SM 840A, JEOL, Japan). The data were analysed statistically with t-test. The results were as follows : 1. Application of chlorhexidine varnish had no significant effect on the shear bond strength of the orthodontic bracket. 2. There was no significant difference in the failure pattern of orthodontic bracket between the experimental group and the control group.

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Vegetational Management Planning of the Namsan Nature Park in Seoul on the Basis of Phytosociological Characteristics (식물사회학적 특성을 고려한 남산공원 식생의 관리대책)

  • Oh, Koo Kyoon;Lee, Kyong Jae;Yim, Kyong Bin
    • Journal of Korean Society of Forest Science
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    • v.77 no.1
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    • pp.1-9
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    • 1988
  • To analyze phytosociological characteristics of the Mt. Namsan nature park, Seoul, vegetation structure of north-east and south-west slopes, competition capability among species, vegetation structures of afforested species were studied with belt-transect and quadrat methods. And management plan of each vegetational zone was proposed by the results of this study and the other previous reports. Numbers of species and individuals of south-west slope were greater than those of north-east slope. But species diversity of northeast showed stability of 1.0, while that of south-west showed instability from 0.8 to 1.3. The floristic dissimilarity coefficient between two slopes showed 70-80% in which species composition between two slopes was much different. Quercus mongolica was a dominant species at north-east slope and Pinus densiflora at south-west slope. Competition capability among major species was resulted in deciduous trees>Robinia pseudoacacia>Populus alba ${\times}$ glandulosa>Pinais densiflora, Quercus mongolica>deciduous trees>Pinus densiflora. Afforested vegetation at the Mt. Namsan, especially Pinus koraiensis, Abies holophylla, Picea abies, etc showed poor growth rate. The goal of the Nam-san nature park management is to conserve natural ecosystem as it is and, if necessary, to accerlerate restoration of the disturbed ecosytem to its nature by minimum energy input as possible. Management proposal was made for six vegetational management zone ; P. derasitZoru forest zone, Q. mongolica forest zone, deciduous forest zone, afforestation zone, R. pseduoacacia zone and landscape planting zone.

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Production of Free D-amino Acids in Raw Milk Related to Psychrotrophic Bacterial Contamination (원유내 내냉성 미생물의 오염에 따른 유리 D-amino acid의 생성)

  • Kim, C.H.;Song, Y.M.;Baick, S.C.
    • Journal of Animal Science and Technology
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    • v.46 no.1
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    • pp.91-96
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    • 2004
  • It is generally believed that amino acids occurring naturally in mammals are of the L-configuration. D-amino acid(DM) are common in nature as constituents of bacterial cell walls and several antibiotics. Recent reports have demonstrated the presence of small amounts of free DM in milk. The presence of free DM may affect the food quality by decreasing the nutritional value. Our objective was to examine whether the free DM carne from psychrotrophic bacteria. Free DM was produced by treating raw milk with Pseudomonas spp. The samples were extracted with sulphosalicylic acid and derivatized with AccQ-$Tag^{TM}$ reagent when the analysis was carried out by reverse-phase HPLC. We tested correlations of the content of free DM with bacterial growth. Significant amounts of free D-a1anine and D-proline have been found in the raw milk inoculated with Pseudomonas spp. The increase of D-alanine and D-proline appeared to be mainly related to the presence of Pseudomonas fluorescens. These results suggest that free DM may be considered as an indicator of psychrotrophic bacterial milk contamination.

Cluster Analysis and Growth Characteristics of Hemp (Cannabis sativa L.) Germplasm (저 마약형 대마 유전자원의 생육특성 및 품종군 분류)

  • Moon Youn-Ho;Song Yeon-Sang;Jeong Byeong-Choon;Bang Jin-Ki
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.51 no.5
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    • pp.483-490
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    • 2006
  • In order to breed hemp variety with nondrug type adapted to Korea, a total of 44 accessions were introduced from Center for plant breeding and reproduction research (CPRO) In Netherland and evaluated for plant growth characteristics and contents of cannabinoids such as tetrahydrocannbinol (THC), cannabidiol (CBD), Cannabinol (CBN) in Korean climatical and geographical condition. 1. In Korean geographical position which latitude is $34^{\circ}N$, days to flowering and stem length were shorter than in Netherlands which latitude is $52^{\circ}N$. But THC content was not shown significant difference between two areas. 2. Corrected accessions of hemp were classified into 3 variety groups by cluster analysis and 4 accessions including Korean local variety were not classified into any variety group. 3. Most hemp accessions have low THC contents but were not suitable for fiber production in Korea due to short days to flowering and stem length. 4. Among the introduced accessions, IH3 was suitable for breeding material of fiber hemp with non-drug type because of low THC content and similar days to flowering with Korean local variety.

Validation of Reference Genes for Quantifying Changes in Physiological Gene Expression in Apple Tree under Cold Stress and Virus Infection (저온과 바이러스 감염에 노출된 사과나무의 생리적 유전자 정량 측정용 유전자들의 발현 분석 및 검증)

  • Yoon, Ju-Yeon;Jeong, Jae-Hoon;Choi, Seung-Kook
    • Research in Plant Disease
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    • v.26 no.3
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    • pp.144-158
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    • 2020
  • Quantitative reverse transcription PCR is used for gene expression analysis as the accurate and sensitive method. To analyze quantification of gene expression changes in apple plants, 10 housekeeping genes (ACT, CKL, EF-1α, GAPDH, MDH, PDI, THFs, UBC, UBC10, and WD40) were evaluated for their stability of expression during infection by Apple stem grooving virus (ASGV) or in cold-stress apple plant buds. Five reference-gene validation programs were used to establish the order of the most stable genes for ASGV as CKL>THFs>GAPDH>ACT, and the least stable genes WD40CKL>UBC10, and the least stable genes were ACT

Case Study on the detailed standard setting and Application for QRA in Honam high speed railway tunnel (호남고속철도터널의 정량적 위험도 분석(QRA)을 위한 세부기준수립 및 적용사례)

  • Kim, Seon-Hong;Moon, Yeon-Oh;Seok, Jin-Ho;Kim, Ki-Lim;Kim, Chan-Dong;Yoo, Ho-Sik
    • Proceedings of the Korean Society for Rock Mechanics Conference
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    • 2008.10a
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    • pp.249-260
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    • 2008
  • Although the accident rate is lower than the road tunnel, fire in railway tunnel can bring large damage of human life. In the high speed railway tunnel, the possibility of the railway-disaster (fire) is growing in consideration of the speedy railway and the tunnel length. For that reason, MLTM (Ministry of Land, Transport and Maritime Affairs) published "Rules about the Safety Standard of Railroad (2005.10.27)" and "The Detailed Safety Standard of Railroad (2006.9.22)". According to those, QRA(Quantitative Risk Analysis) technique is recommended to be applied to railway tunnel design which is longer than 1km for assuring the safety function and estimating the risk. However, it is difficult to perform the disaster prevention design due to lack of the detailed standards about event scenario, fire intensity, incidence rate of accidents etc. Therefore, This paper introduces the case of tunnel design for disaster prevention of the Honam high speed railway including the detailed standards of QRA and reasonable safety facilities.

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How Do People Experience Changes and Growths of the Self in On-line Game World? (온라인 게임 세계 속에서 게임 사용자들은 시간이 흐름에 따라 자신의 모습에서 어떠한 변화와 성장을 경험하는가?)

  • Do, Young-Yim;Whang, Sang-Min
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.1208-1217
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    • 2009
  • This research was conducted in an attempt to understand changes and growths of the self in on-line game world. Q methodology was used to investigate players in Mabinogi, which is an on-line game(MMORPG). Based on 57 behavior statements, Players distributed their changing experiences from when they were novices in on-line game world to the current state. In early start phase, they recognized that on-line game world was different from the reality. And they perceived their experiences in on-line game as separated from the real ones. However, as they spend more time in on-line game world, they began to realized that on-line game world is as real as the world because they function as an individual living in a society in both the game and the real world. They felt and learned that in on-line game life, they also need to follow the rules and order. In addition, trust and politeness were essential in order to live with other players. As time passed, the players realized that on-line game experiences have the same meanings and values as the real life ones. 3 types of self-changing patterns were found : Achievement change, Control change, and Relation change. The behavior patterns of the 3 types were then compared to Identify similarities and differences amongst them in psychological meanings and values in the on-line game life. This result illustrates that on-line game world can be defined as new behavioral setting or developmental context established by digital technology. In this new setting, people can experiment and understand their behavior patterns and also experience changes and growths of the self.

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Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway

  • Zhou, Wei;Quan, Juan-Hua;Gao, Fei-Fei;Ismail, Hassan Ahmed Hassan Ahmed;Lee, Young-Ha;Cha, Guang-Ho
    • Parasites, Hosts and Diseases
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    • v.56 no.2
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    • pp.135-145
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    • 2018
  • Due to the critical location and physiological activities of the retinal pigment epithelial (RPE) cell, it is constantly subjected to contact with various infectious agents and inflammatory mediators. However, little is known about the signaling events in RPE involved in Toxoplasma gondii infection and development. The aim of the study is to screen the host mRNA transcriptional change of 3 inflammation-related gene categories, PI3K/Akt pathway regulatory components, blood vessel development factors and ROS regulators, to prove that PI3K/Akt or mTOR signaling pathway play an essential role in regulating the selected inflammation-related genes. The selected genes include PH domain and leucine- rich-repeat protein phosphatases (PHLPP), casein kinase2 (CK2), vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), glutamate-cysteine ligase (GCL), glutathione S-transferase (GST), and NAD(P)H: quinone oxidoreductase (NQO1). Using reverse transcription polymerase chain reaction (RT-PCR) and quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR), we found that T. gondii up-regulates PHLPP2, $CK2{\beta}$, VEGF, GCL, GST and NQO1 gene expression levels, but down-regulates PHLPP1 and PEDF mRNA transcription levels. PI3K inhibition and mTOR inhibition by specific inhibitors showed that most of these host gene expression patterns were due to activation of PI3K/Akt or mTOR pathways with some exceptional cases. Taken together, our results reveal a new molecular mechanism of these gene expression change dependent on PI3K/Akt or mTOR pathways and highlight more systematical insight of how an intracellular T. gondii can manipulate host genes to avoid host defense.