• Title/Summary/Keyword: Pure sciences

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Microsatellite-based Genetic Diversity and Evolutionary Relationships of Six Dog Breeds

  • Ye, J.-H.;Ren, D.-R.;Xie, A.-F.;Wu, X.-P.;Xu, L.;Fu, P.-F.;Zhao, H.-A.;Yang, Qianyong
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.8
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    • pp.1102-1106
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    • 2009
  • The Tibetan Mastiff is one of the most archaic, ferocious and the largest dogs in the world. The Kunming dog is the chief working-dog breed in China. In this study, ten microsatellite loci were used to assess the genetic diversity and evolutionary relationships in six dog breeds, including Tibetan Mastiff, Kunming dog, Belgian Malinois, Labrador Retriever, English Springer Spaniel, and German Shepherd. The highest genetic diversity was exhibited by the Tibetan Mastiff, indicating useful protection and little inbreeding in the modern Tibetan Mastiff. Higher genetic diversity was observed in European breeds, supporting the hypotheses that breeders outcross their pure breed dogs occasionally to avoid deleterious effects in Europe. Evolutionary relationships showed that English Springer Spaniel and Labrador Retriever were clustered together, then with the Tibetan Mastiff, consistent with previous cluster results. German Shepherd and Kunming dog were grouped together, coinciding with the breeding history of Kunming dog. It is the first time that Tibetan Mastiff and Kunming dog have been analyzed with microsatellites.

Test Methods of a TRNG (True Random Number Generator) (TRNG (순수 난수 발생기)의 테스트 기법 연구)

  • Moon, San-Gook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2007.06a
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    • pp.803-806
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    • 2007
  • Since the different characteristics from the PRNG (Pseudo Random Number Generator) or various deterministic devices such as arithmetic processing units, new concepts and test methods should be suggested in order to test TRNG (Ture Random Number Generator). Deterministic devices can be covered by ATPG (Automatic Test Pattern Generation), which uses patterns generated by cyclic shift registers due to its hardware oriented characteristics, pure random numbers are not possibly tested by automatic test pattern generation due to its analog-oriented characteristics. In this paper, we studied and analyzed a hardware/software combined test method named Diehard test, in which we apply continuous pattern variation to check the statistics. We also point out the considerations when making random number tests.

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Preparation of Amorphous Adefovir dipivoxil using Reverse Phase Column Chromatography and Solid Dispersion Method (역상컬럼 및 고체분산체를 이용한 무정형 아데포비어디피복실의 제조)

  • Yoon, Myeong-Sik;Oh, Da-Won;Maeng, Hyo-Chan;Hong, Hye-Suk;Park, Mi-Kyung;Lee, Yong-Tack;Lee, Si-Beum;Cho, Il-Hwan;Moon, Byoung-Seok
    • YAKHAK HOEJI
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    • v.54 no.4
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    • pp.316-321
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    • 2010
  • Adefovir dipivoxil which was originally developed by Gilead Sciences has been used as treatments of HIV and HBV, especially a therapeutics for HBeAg positive and negative chronic patients. We developed highly efficient purification method using reverse phase column chromatography for mass production and a stable amorphous Adefovir dipivoxil using solid dispersion method. Reverse phase column chromatography led to highly pure product, more than 99.7% by HPLC and can be used for mass production compared with normal column chromatography. Solid dispersion method containing watersoluble polymer and Isomalt showed improved stability of amorphous Adefovir dipivoxil against heat and moisture.

Effects of solanum macrocarpon (African eggplant) on haematological parameters of wistar rats exposed to urban air pollution

  • Olajire, A.A.;Azeez, L.
    • Advances in environmental research
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    • v.1 no.2
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    • pp.109-123
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    • 2012
  • Our study investigated the effects of Solanum macrocarpon (African eggplant) on haematological and biochemical parameters of male albino rats exposed to urban air pollution ($O_3$, $PM_{10}$, CO, $SO_2$, $NO_2$ and VOC). Male albino Wistar rats were exposed for 63 days either to urban air pollution without treatment (A); oral supplementation with Solanum macrocarpon given at 36 and 75 mg/kg body weight (BW), representing C and D respectively and exposed to air pollution; oral supplementation with Solanum macrocarpon given at 75 mg/kg BW after exposure to air pollution (B); or kept in animal house without exposure to air pollution (E). Animals exposed to air pollution showed significant alterations in haematological and biochemical parameters signaling that the blood and organs were badly injured. There were significant elevations in white blood cells (WBC) and its indices, reduction in red blood cells (RBC) and significant depletions of non-enzymic antioxidants, total protein and increase in lipid peroxidation values. Solanum macrocarpon supplementation in the feed of animals halted significantly the deleterious effects of air pollution, with co-administration during exposure given better results.

Phylogenetic Analysis of Culturable Arctic Bacteria

  • Lee Yoo Kyung;Kim Hyo Won;Kang Sung-Ho;Lee Hong Kum
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2003.05a
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    • pp.26-33
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    • 2003
  • We isolated and identifed culturable Arctic bacteria that have inhabited around Korean Arctic Research Station Dasan located at Ny-Alsund, Svalbard, Norway $(79^{\circ}N,\;12^{\circ}E)$. The pure colonies were inoculated into nutrient liquid media, genomic DNA was extracted, and phylogenetic analysis was performed on the basis of 16S rDNA sequences. Out of total 227 strains, 198 strains were overlapped or unidentified, and 43 bacteria were finally identified: 31 strains belonged to Pseudomonas, 7 strains Arthrobacter, two Flavobacterium sp., an Achromobacter sp., a Pedobacter sp., and a Psychrobacter sp. For isolation of diverse bacteria, we need more effective transport method than 3M petri-films, which were used for convenience of transportation that was restricted by volume. We also need to use other culture media than nutrient media. We expect these Arctic bacteria can be used for screening to develop new antibiotics or industrial enzymes that are active at low temperature.

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Poliovirus Decrease Effect by Activated Sludge Microbes (활성슬러지 구성 미생물에 의한 폴리오바이러스의 감소 효과)

  • Kim, Tae-Dong;Choi, Dong-Hyuk
    • Journal of Environmental Health Sciences
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    • v.32 no.4 s.91
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    • pp.336-341
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    • 2006
  • The biological wastewater treatment system is known to have an important role in reducing the quantify of enteric virus in water environments. To clarify the roles of activated sludge microbes in decreasing the virus infectivity, the behavior of the virus in bacteria, protozoa, and metazoa was examined by pure or mixed culture system using poliovirus type 1(Lsc, 2ab strain). In the bacterial culture systems, the virus infectivity in the liquid phase decreased by a reversible adsorption of the virus to the bacteria or bacterial flocs. On the other hand, in the protozoa and the metazoa culture systems using T. pyriformis and P. erythrophthalma, respectively, with a variety of bacterial strains as prey, the main virus decrease mechanism of reversible adsorption in early stage was changed to irreversible predation, which was not eluted in this study. The virus decrease was more effective in the P. erythrophthalma culture system, which had high predation and floc forming abilities. However, in the mixed culture system of Z. ramigera and P. erythrophthalma, the more rapid reversible adsorption of virus to Z. ramigera flocs preceded the irreversible predation of P. erythrophthalma.

Effects of Magnetite added with Metallic Oxide on the Decomposition Reaction of Carbon Dioxide (CO$_2$ 분해 반응에서 금속 산화물이 첨가된 $Fe_2O_4$의 영향)

  • Kim, Seung-Ho;Park, Young-Goo
    • Journal of Environmental Health Sciences
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    • v.24 no.1
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    • pp.32-37
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    • 1998
  • The Carbon Dioxide is the gas, which causes green house effects, unusual changes in the weather, destruction of the life. Almost every nation in the world is trying to search the countermeasure to this poisonous gas. I synthesized $Fe_3O_4$ and NaOH, in order to decompose the Carbon Dioxide. Among the particles synthesizing $Fe_3O_4$, I chose the equivalent ratio 1.00 which can decompose the Carbon Dioxide best, and fixed that equivalent ratio and added the 0.005-3.00 mole percentage of NiCl$_2$ and synthesized $Fe_3O_4$. I studied the decomposition of the Carbon Dioxide and methanized reaction, by measuring its crystal structure, thermochemistrical character and specific surface area. In decomposing the Carbon Dioxide, I used oxygen-deficit Magnetite which I produced by injecting the hydrogen gas into the synthesized sample. I observed the methanization reaction by raising the temperature of sample up to 650$\circ$C and having it reacted with the hydrogen gas. The decomposition of the Carbon Dioxide was added 0.005, 0.03, 0.05 mole percentage of NiCl$_2$ was more effective than pure $Fe_3O_4$. All sample in which the decomposition of the Carbon Dioxide took place produced the methane gas.

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Photocatalytic Decomposition of Methylene Blue over Sm Ion Doped Ti-SBA-15 Catalysts (Sm이온이 도핑된 Ti-SBA-15 촉매에서의 메틸렌블루의 광촉매 분해 반응)

  • Jung, Won-Young;Lee, Seong-Hun;Hong, Seong-Soo
    • Journal of Environmental Science International
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    • v.20 no.4
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    • pp.511-517
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    • 2011
  • Ti-SBA-15 catalysts doped with samarium ion were synthesized using conventional hydrothermal method. The physical properties of Sm/Ti-SBA-15 catalysts have been characterized by XRD, FT-IR, DRS and PL. In addition, we have also examined the activity of these materials on the photocatalytic decomposition of methylene blue. The Sm/ Ti-SBA-15 was shown to have the mesoporous structure regardless of Sm ion doping. With doping amount of 1% lanthanide ion, the pore size and pore volume of Sm(Er, Cs)/Ti-SBA-15 decreased and the surface area increased. For the purpose of vibration characteristics on the Ti-SBA-15 and Sm/Ti-SBA-15 photocatalysts, the IR absorption at 960 $cm^{-1}$ commonly accepted the characteristic vibration of Ti-O-Si bond. 1% of Sm/Ti-SBA-15 had the highest photocatalytic activity on the decomposition of methylene blue but the catalysts doped with Er ions had lower activity in comparison with pure Ti-SBA-15 catalyst.

In-situ Preparation of Eco-friendly Hydrpxyapatite/Waterborne Polyurethane Composites (환경친화형 하이드록시아파타이트/수분산 폴리우레탄 복합체의 in-situ 제조)

  • Lee, Jun-Gun;Lee, Won-Ki;Park, Sang-Bo;Park, Chan-Young;Min, Sung-Kee;Jang, Sung-Ho
    • Journal of Environmental Science International
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    • v.21 no.4
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    • pp.507-515
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    • 2012
  • To improve the mechanical properties of hydroxyapatite (HA)/waterborne polyurethane (WBPU) composites, the hydroxyl group of HA was modified by urethane reactions: the hydroxyl groups of HA were reacted with aliphatic or cyclic diisocyanate, and then the modified HAs were extended by adding polyol and/or ${\varepsilon}$-caprolactone. Composites were prepared by the prepolymer process method: the modified HA was directly pured into the urethane reaction of isocyanate and polyol. The properties of modified HA/WBPU composites were investigated by thermogravimetric analysis, tensile strength, and water resistance. The results showed that the reactivity of aliphatic diisocyanate to the hydroxy group of HA was faster than that of cyclic one. Comparing to those of pure HA/WBPU composite films, the thermal stability, water resistance, and mechanical properties of the modified composite films increased with a degree of modification of HA.

Effect on 4H-SiC Schottky Rectifiers of Ar Discharges Generated in A Planar Inductively Coupled Plasma Source

  • Jung, P.G.;Lim, W.T.;Cho, G.S.;Jeon, M.H.;Lee, J.W.;Nigam, S.;Ren, F.;Chung, G.Y.;Macmillan, M.F.;Pearton, S.J.
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.3 no.1
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    • pp.21-26
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    • 2003
  • 4H-SiC Schottky rectifiers were exposed to pure Ar discharges in a planar coil Inductively Coupled Plasma system, as a function of source power, of chuck power and process pressure. The reverse breakdown voltage ($V_B$) decreased as a result of plasma exposure due to the creation of surface defects associated with the ion bombardment. The magnitude of the decrease was a function of both ion flux and ion energy. The forward turn-on voltage ($V_F$), on-state resistance ($R_{ON}$) and diode ideality factor (n) all increased after plasma exposure. The changes in all of the rectifier parameters were minimized at low power, high pressure plasma conditions.