• Title/Summary/Keyword: Pure Potential

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Andrographolides and traditionally used Andrographis paniculata as potential adaptogens: Implications for therapeutic innovation

  • Thakur, Ajit Kumar;Chatterjee, Shyam Sunder;Kumar, Vikas
    • CELLMED
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    • v.4 no.3
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    • pp.15.1-15.14
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    • 2014
  • Andrographis paniculata (Burm. F.) Wall. Ex Nees (Family: Anthaceae) is a traditionally known Ayurvedic medicinal plant. Several well-controlled clinical trials conducted during recent years have consistently reconfirmed that Andrographis paniculata extracts are effective in suppressing cardinal symptoms of diverse inflammatory and infectious diseases. Despite extensive efforts though, many questions concerning bioactive constituents of such extracts and their modes of actions still remain unanswered. Amongst diverse diterpene lactones isolated to date from such extracts, andrographolide is often considered to be the major, representative, or bioactive secondary metabolite of the plant. Therefore, it has attracted considerable attention of several drug discovery laboratories as a lead molecule potentially useful for identifying structurally and functionally novel drug. Critical analysis of available preclinical and clinical information on Andrographis paniculata extracts and pure andrographolide strongly suggest that they are pharmacologically polyvalent and that they possess adaptogenic properties. Aim of this communication is to summarize and critically analyze such data, and to point out some possibilities for more rationally exploiting their adaptogenic properties for discovering novel therapeutic leads, or for obtaining pharmacologically better standardized phyto-pharmaceuticals.

Optimized Synthesis Conditions of Polyethersulfone Support Layer for Enhanced Water Flux for Thin Film Composite Membrane

  • Son, Moon;Choi, Hyeongyu;Liu, Lei;Park, Hosik;Choi, Heechul
    • Environmental Engineering Research
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    • v.19 no.4
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    • pp.339-344
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    • 2014
  • Different types of polyethersulfone (PES) support layer for a thin film composite (TFC) membrane were synthesized under various synthesis conditions using the phase inversion method to study the combined effects of substrate, adhesive, and pore former. The permeability, selectivity, pore structure, and morphology of the prepared membranes were analyzed to evaluate the membrane performance. The combined use of substrate, adhesive, and pore former produced a thinner dense top layer, with more straight finger-like pores. The pure water permeation (PWP) of the optimized PES membrane was $27.42L/m^2hr$ (LMH), whereas that of bare PES membrane was 3.24 LMH. Moreover, membrane selectivity, represented as divalent ion ($CaSO_4$) rejection, was not sacrificed under the synthesis conditions, which produced the dramatically enhanced PWP. The high permeability and selectivity of the PES membrane produced under the optimized synthesis conditions suggest that it can be utilized as a potential support layer for TFC membranes.

Enhanced Electrocatalytic Activity of Low Ni Content Nano Structured NiPd Electrocatalysts Prepared by Electrodeposition Method for Borohydride Oxidation

  • Zolfaghari, Mahdieh;Arab, Ali;Asghari, Alireza
    • Journal of Electrochemical Science and Technology
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    • v.11 no.3
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    • pp.238-247
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    • 2020
  • Some nano structured bimetallic NiPd electrocatalysts were electrodeposited on glassy carbon electrodes using a double potential step chronoamperometry. The morphology of the electrodeposited samples was investigated by field emission-scanning electron microscopy, while their compositions were evaluated using energy dispersive X-ray spectroscopy. It was observed that the electrodeposited samples contained a low Ni content, in the range of 0.80 - 7.10%. The electrodeposited samples were employed as the anode electro-catalysts for the oxidation of sodium borohydride in NaOH solution (1.0 M) using cyclic voltammetry, chronoamperometry, rotating disk electrode, and impedance spectroscopy. The number of exchanged electrons, charge transfer resistances, apparent rate constants, and double layer capacitances were calculated for the oxidation of borohydride on the prepared catalysts. According to the results obtained, the NiPd-2 sample with the lowest Ni content (0.80%), presented the highest catalytic activity for borohydride oxidation compared with the other NiPd samples as well as the pure Pd sample. The anodic peak current density was obtained to be about 1.3 times higher on the NiPd-2 sample compared with that for the Pd sample.

Low molecular amorphous spirobifluorene derivatives for blue electroluminescence

  • Lee, Hyo-Young;Oh, Ji-Young;Chu, Hye-Yong;Lee, Jeong-Ik;Kim, Seong-Hyun;Yang, Yong-Suk;Do, Lee-Mi;Zyung, Tae-Hyoung
    • 한국정보디스플레이학회:학술대회논문집
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    • 2001.08a
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    • pp.209-212
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    • 2001
  • We report the synthesis and characterization of new alkoxy substituted spirobifluorene derivatives. The spiro compounds having alkoxy hydrocarbon chains were readily soluble in common organic solvents, having improved film-forming properties and had a significantly reduced tendency to crystallize, resulting in increasing their service lifetime. The results of DSC showed that it was amorphous. The optical and electroluminescent spectra were characterized. Electroluminescence (EL) properties of three-layer light emitting diodes (LED) of $ITO/TPD/spirobifluorene/Alq_3/LiF/Al$ as the active layer were characterized. Blue emission peaking of the EL spectrum of the three-layer device at 402 nm and a luminance of 3,125 $cd/m^2$ were achieved at a drive voltage 12.8 V. The luminous efficiency was obtained to be 1.7 lm/W. The color coordinate in CIE chromaticity is (0.16, 0.09), which is in a pure blue region. The external quantum efficiency was obtained to be 2.0%. The results indicate that the spirobifluorene compounds having alkoxy hydrocarbon chains are strongly potential blue emitters for LED applications.

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Layer-by-layer assembled graphene oxide films and barrier properties of thermally reduced graphene oxide membranes

  • Kim, Seon-Guk;Park, Ok-Kyung;Lee, Joong Hee;Ku, Bon-Cheol
    • Carbon letters
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    • v.14 no.4
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    • pp.247-250
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    • 2013
  • In this study, we present a facile method of fabricating graphene oxide (GO) films on the surface of polyimide (PI) via layer-by-layer (LBL) assembly of charged GO. The positively charged amino-phenyl functionalized GO (APGO) is alternatively complexed with the negatively charged GO through an electrostatic LBL assembly process. Furthermore, we investigated the water vapor transmission rate and oxygen transmission rate of the prepared (reduced GO $[rGO]/rAPGO)_{10}$ deposited PI film (rGO/rAPGO/PI) and pure PI film. The water vapor transmission rate of the GO and APGO-coated PI composite film was increased due to the intrinsically hydrophilic property of the charged composite films. However, the oxygen transmission rate was decreased from 220 to 78 $cm^3/m^2{\cdot}day{\cdot}atm$, due to the barrier effect of the graphene films on the PI surface. Since the proposed method allows for large-scale production of graphene films, it is considered to have potential for utilization in various applications.

Platycosides from the Roots of Platycodon grandiflorum and Their Health Benefits

  • Nyakudya, Elijah;Jeong, Jong Hoon;Lee, Nam Keun;Jeong, Yong-Seob
    • Preventive Nutrition and Food Science
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    • v.19 no.2
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    • pp.59-68
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    • 2014
  • The extracts and pure saponins from the roots of Platycodon grandiflorum (PG) are reported to have a wide range of health benefits. Platycosides (saponins) from the roots of PG are characterized by a structure containing a triterpenoid aglycone and two sugar chains. Saponins are of commercial significance, and their applications are increasing with increasing evidence of their health benefits. The biological effects of saponins include cytotoxic effects against cancer cells, neuroprotective activity, antiviral activity, and cholesterol lowering effects. Saponins with commercial value range from crude plant extracts, which can be used for their foaming properties, to high purity saponins such as platycodin D, which can be used for its health applications (e.g., as a vaccine adjuvant). This review reveals that platycosides have many health benefits and have the potential to be used as a remedy against many of the major health hazards (e.g., cancer, obesity, alzheimer's) faced by populations around the world. Methods of platycoside purification and analysis are also covered in this review.

3D Printable Composite Materials: A Review and Prospective (3D 프린터용 복합재료 연구 동향)

  • Oh, Eunyoung;Lee, Jinwoo;Suhr, Jonghwan
    • Composites Research
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    • v.31 no.5
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    • pp.192-201
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    • 2018
  • The use of 3D printing for rapid tooling and manufacturing has promised to produce components with complex geometries according to computer designs and it is emerging as the next generation key of manufacturing. Due to the intrinsically limited mechanical/electrical properties and functionalities of printed pure polymer parts, there is a critical need to develop 3D printable polymer composites with high performance. This article gives a review on 3D printing techniques of polymer composite materials and the properties and performance of 3D printed composite parts as well as their potential applications in the various fields.

Opportunistic Spectrum Access with Dynamic Users: Directional Graphical Game and Stochastic Learning

  • Zhang, Yuli;Xu, Yuhua;Wu, Qihui
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.12
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    • pp.5820-5834
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    • 2017
  • This paper investigates the channel selection problem with dynamic users and the asymmetric interference relation in distributed opportunistic spectrum access systems. Since users transmitting data are based on their traffic demands, they dynamically compete for the channel occupation. Moreover, the heterogeneous interference range leads to asymmetric interference relation. The dynamic users and asymmetric interference relation bring about new challenges such as dynamic random systems and poor fairness. In this article, we will focus on maximizing the tradeoff between the achievable utility and access cost of each user, formulate the channel selection problem as a directional graphical game and prove it as an exact potential game presenting at least one pure Nash equilibrium point. We show that the best NE point maximizes both the personal and system utility, and employ the stochastic learning approach algorithm for achieving the best NE point. Simulation results show that the algorithm converges, presents near-optimal performance and good fairness, and the directional graphical model improves the systems throughput performance in different asymmetric level systems.

A Theoretical Study on Driving Distance of Compressed Air Vehicle Using Scroll Expander (스크롤 팽창기를 적용한 압축공기 엔진 자동차의 주행거리 특성에 관한 연구)

  • Shin, Donggil
    • Journal of Energy Engineering
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    • v.25 no.4
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    • pp.170-175
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    • 2016
  • An internal combustion engine is the most widely used power source for an automobile. In order to resolve environmental problems resulting from the use of internal combustion engines, environmentally friendly automobiles such as hybrid, electric, and air-engine vehicles are being developed. The share of hybrid vehicles using battery or pure electric vehicles, which are not popular, is gradually increasing. Compared to an electric vehicle, which uses an electric motor, air-engine vehicles, which use compressed air, have hardly been developed. In this study, a compressed air engine with a scroll expander is introduced, and the potential mileage of an automobile utilizing this engine is theoretically calculated.

Optimum Evaluation of Reinforcement Cord of Air Spring for the Vehicle Suspension System (자동차 현가장치를 위한 에어스프링 보강코드의 최적 성능평가)

  • Kim, Byeong-Soo;Moon, Byung-Young
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.3
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    • pp.357-362
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    • 2011
  • Air springs are prevalently used as suspension in train. However, air springs are seldom used in automobiles where they improve stability and comfort by enhancing the impact-relief, breaking, and cornering performance. Thus, this study proposed a new method to analyze air springs and obtained some reliable design parameter which can be utilized in vehicle suspension system in contrast to conventional method. Among air spring types of suspension, this study focused on sleeve type of air spring as an analysis model since it has potential for ameliorating the quality of automobiles, specifically in its stability and comfort improvement by decreasing the shock through rubber sleeve. As a methodology, this study used MARC, as a nonlinear finite element analysis program, in order to find out maximum stress and maximum strain depending on reinforcement cord's angle variation in sleeves. The properties were found through uniaxial tension and pure shear test, and they were developed using Ogden Foam which is an input program of MARC. As a result, the internal maximum stresses and deformation according to the changes of cord angle are obtained. Also, the results showed that the Young's modulus becomes smaller, then maximum stresses decrease. It is believed that these studies can be contributed in automobile suspension system.