• Journal of Preventive Medicine and Public Health
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• v.42 no.6
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• pp.356-359
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• 2009

In the more than 100 genome wide association studies (GWAS) conducted in the past 5 years, more than 250 genetic loci contributing to more than 40 common diseases and traits have been identified. Whilst many genes have been linked to a trait, both their individual and combined effects are small and unable to explain earlier estimates of heritability. Given the rapid changes in disease incidence that cannot be accounted for by changes in diagnostic practises, there is need to have well characterized exposure information in addition to genomic data for the study of gene-environment interactions. The case-control and cohort study designs are most suited for studying associations between risk factors and occurrence of an outcome. However, the case control study design is subject to several biases and hence the preferred choice of the prospective cohort study design in investigating geneenvironment interactions. A major limitation of utilising the prospective cohort study design is the long duration of follow-up of participants to accumulate adequate outcome data. The GWAS paradigm is a timely reminder for traditional epidemiologists who often perform one- or few-at-a-time hypothesis-testing studies with the main hallmarks of GWAS being the agnostic approach and the massive dataset derived through large-scale international collaborations.

• Asia-Pacific Journal of Business
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• v.11 no.2
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• pp.99-118
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• 2020

Purpose - The purpose of this study analyzes the effect of emotional intelligence on entrepreneurship mediated by personal creativity, and an effective. Design/methodology/approach - A questionnaire was administered to approximately 141 students. Collected data were analyzed using SPSS 26.0 and AMOS statistical package. Findings - First, emotional intelligence had a positive effect on personal creativity. Second, Personal creativity was found to have a partial mediating effect on the relationship between emotional intelligence and entrepreneurship. Specifically, personal creativity mediated the relationship between emotional expression intelligence and entrepreneurship, but did not mediate the relationship between entrepreneurship and the facilitation of cognitive intelligence. Lastly, prospective entrepreneur's emotional intelligence is seen to have a positive effect on entrepreneurship, and personal creativity plays a role in mediating between emotional intelligence and entrepreneurship. Therefore, supplementary measures are needed to place more importance on emotional intelligence in entrepreneurship education related to starting a business, which had not been appropriately addressed until now. Research implications or Originality - The implications of this study are that policies are needed to develop entrepreneurship skills in those who are interested in starting a business, and that follow-up studies on entrepreneurship are needed.

• KIPS Transactions on Computer and Communication Systems
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• v.12 no.1
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• pp.25-40
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• 2023

Recommendation systems are frequently used by users to generate intelligent automatic decisions. In the study of movie recommendation system, the existing approach uses largely collaboration and content-based filtering techniques. Collaborative filtering considers user similarity, while content-based filtering focuses on the activity of a single user. Also, mixed filtering approaches that combine collaborative filtering and content-based filtering are being used to compensate for each other's limitations. Recently, several AI-based similarity techniques have been used to find similarities between users to provide better recommendation services. This paper aims to provide the prospective expansion by deriving possible solutions through the analysis of various existing movie recommendation systems and their challenges.

• 제어로봇시스템학회:학술대회논문집
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• 1994.10a
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• pp.152-155
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• 1994

The presence of joint elasticity or the arm flexibility causes low damped oscillatory position error along a desired trajectory. We utilize a stochastic model for describing the fast dynamics and the approximation error. A second order shaping filter is synthesized such that its spectrum matches that of the fast dynamics. Augmenting the state vector of slow part with that of shaping filter, we obtain a nonlinear dynamics to which a Gaussian white noise is injected. This modeling approach leads us to the design of an extended Kalman filter(KEF) and a linear quadratic Gaussian(LQG) control scheme. We present the simulation results of this control method. The simulation results show us that our Kalman filtering approach is one of prospective methods in controlling the flexible arms.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.11a
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• pp.459-468
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• 2009

Analysis of the uncertainty to have engineering solution of gas-dynamic and hydrodynamic problems is based on the comparison the prospective engineering solution with experimental result. In this paper, the mathematical model to estimate heat flux along gas-dynamic channel wall and the solution sequence are shown. Statistical information and generalizing experimental characteristics about gas- and hydro-dynamic channels were applied to the mathematical model. As the results, it is possible to draw a conclusion that models of the integrated approach, using the averaged statistical data of generalizing characteristics for a turbulent flow, without consideration of the turbulent mechanism (characteristic pulsations), can predict a nominal operating regime for gas-dynamic and hydrodynamic systems. The probable deviation of operating regime for newly designed the gas-dynamic channel can achieve 20% from a regime predicted on a basis 1-D or 3-D modelling irrespective of a kind of used models.

• Nuclear Engineering and Technology
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• v.37 no.3
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• pp.231-244
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• 2005

In recent decades, significant effort has led to risk-informed improvements to regulation. Performance-based approaches also promise significant gains in efficiency (level of safety versus effort). However, significant work remains to be done before performance-based approaches realize their full potential in regulation of nuclear power plants. This paper reviews key concepts related to performance-based regulation, discusses some applications of performance-based approaches, and identifies issues that still need to be addressed. Realistic, experience-based models of licensee performance are still lacking; this makes it difficult to assess the prospective effectiveness of any given regulatory approach, in light of the performance issues that it will actually face. Also, while 'compliance' is an intuitively straightforward concept to apply within a prescriptive implementation, its analog in a performance-based approach remains unclear. An overarching theme of the paper is that formal methods of decision analysis are very helpful in developing appropriate regulatory approaches, especially performance-based ones; this theme is illustrated at several points.

• Journal of Korea Society of Industrial Information Systems
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• v.12 no.5
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• pp.47-53
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• 2007

On account of supporting the full spectrum of content types in enterprises, customers recognize the problems of the conventional way, that is, point solutions for content management. And then they increase the requirement for ECM (Enterprise Content Management) solutions. In this paper, we survey the spectrum of enterprise content, the components, core value, the market landscape, and application cases of ECM, in order to suggesting the prospective customers the approach for enterprise-wide content management.

• Journal of Gastric Cancer
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• v.18 no.1
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• pp.30-36
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• 2018

Purpose: We investigated complications after laparoscopic sentinel basin dissection (SBD) for patients with gastric cancer who were enrolled in a quality control study, prior to the phase III trial of sentinel lymph node navigation surgery (SNNS). Materials and Methods: We analyzed prospective data from a Korean multicenter prerequisite quality control trial of laparoscopic SBD for gastric cancer and assessed procedure-related and surgical complications. All complications were classified according to the Clavien-Dindo Classification (CDC) system and were compared with the results of the previously published SNNS trial. Results: Among the 108 eligible patients who were enrolled in the quality control trial, 8 (7.4%) experienced complications during the early postoperative period. One patient with gastric resection-related duodenal stump leakage recovered after percutaneous drainage (grade IIIa in CDC). The other postoperative complications were mild and patients recovered with supportive care. No complications were directly related to the laparoscopic SBD procedure or tracer usage, and there were no mortalities. The laparoscopic SBD complication rates and patterns that were observed in this study were comparable to those of a previously reported trial. Conclusions: The results of our prospective, multicenter quality control trial demonstrate that laparoscopic SBD is a safe procedure during SNNS for gastric cancer.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.6
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• pp.631-635
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• 2007

Purpose: The classic technique for open reduction of subcondylar fractures is the submandibular approach. The aim of this study was to evaluate clinical result of retromandibular approach to displaced subcondylar fractures. Material and methods: During a period of 24months we perfomed a prospective study with a retromandibular approach in 23 patients with displaced subcondylar fractures. In this article we describe clinical result in 23 patients with follow ups for 3 months after surgery. Preoperatively all patients had malocclusion and radiology demonstrated displacement. Result: The retromandibularl approach for ORIF was good in all case. Mouth opening(M/O) was 49mm. Occlusion was good too. Permanent facial nerve palsy was not detected. Conclusion: Our findings indicate that the retromandibular approach is a safe technique for subcondylar fractures.

• Journal of Digital Contents Society
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• v.12 no.4
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• pp.501-510
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• 2011

Most of electronic medical record systems which have been built in Korean hospitals are based on source oriented medical record approach. These systems hardly satisfy diverse objectives owing to the innate imperfections in system architecture and development methodology. Thus, the hybrid of source oriented and problem oriented approach is highly desirable. The purpose of this study is to present an architecture and methodology required to construct hybrid electronic medical record system and to develop a prototype based on them. Analyzing the clinical processes and data requirements of problem oriented medical record approach we developed a software process model as weel as an architecture model which consists of legacy system, clinical data repository, problem list database, prospective plan database, user interface, and synchronization procedures.