• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1533-1537
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• 2012

In general, breast cancer is the most common malignancy among women in developed as well as some developing countries, often being the second leading cause of cancer mortality after lung cancer. Using a parametric log-logistic model to consider the effects of prognostic factors, the present study focused on the 5-year survival of women with the diagnosis of breast cancer in Southern Iran. A total of 1,148 women who were diagnosed with primary invasive breast cancer from January 2001 to January 2005 were included and divided into three prognosis groups: poor, medium, and good. The survival times as well as the hazard rates of the three different groups were compared. The log-logistic model was employed as the best parametric model which could explain survival times. The hazard rates of the poor and the medium prognosis groups were respectively 13 and 3 times greater than in the good prognosis group. Also, the difference between the overall survival rates of the poor and the medium prognosis groups was highly significant in comparison to the good prognosis group. Use of the parametric log-logistic model - also a proportional odds model - allowed assessment of the natural process of the disease based on hazard and identification of trends.

• Journal of Applied Reliability
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• v.18 no.2
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• pp.104-113
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• 2018

Purpose: This paper proposes the non-periodic preventive maintenance policy based on the level of cumulative hazard intensity. We aim to construct a cost-effectiveness on the proposed model with relaxing the constraint on reliability. Methods: We use the level of cumulative hazard intensity as a condition variable, instead of reliability. Such a level of cumulative hazard intensity can derive the reliability which decreases as the frequency of preventive maintenance action increases. We also model the imperfect preventive maintenance action using the proportional age setback model. Conclusion: We provide a numerical example to illustrate the proposed model. We also analyze how the parameters of our model affect the optimal preventive maintenance policy. The results show that as long as high reliability is guaranteed, the inefficient preventive maintenance action is performed reducing the system operation time. Moreover, the optimal value of the proposed model is sensitive to changes in preventive maintenance cost and replacement cost.

• Journal of the Korean Statistical Society
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• v.36 no.2
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• pp.321-333
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• 2007

In the proportional hazard model with the beta process prior, the posterior computation with the discrete approximation is considered. The time period of interest is partitioned by small intervals. On each partitioning interval, the likelihood is approximated by that of a binomial experiment and the beta process prior is by a beta distribution. Consequently, the posterior is approximated by that of many independent binomial model with beta priors. The analysis of the leukemia remission data is given as an example. It is illustrated that the length of the partitioning interval affects the posterior and one needs to be careful in choosing it.

• Journal of the Korean Data and Information Science Society
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• v.10 no.1
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• pp.103-110
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• 1999

In this paper, we summarize some relative risk estimators under the two sample model with proportional hazard and examine the relative efficiencies of the nonparametric estimators relative to the maximum likelihood estimator of a parametric survival function under random censoring model by comparing their asymptotic variances.

• Journal of Korean Society of Transportation
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• v.29 no.4
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• pp.29-41
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• 2011

This study investigates the factor that influences commuting time to work when individuals allocate their time for different types of activities. The commuting time is an important indicator for an individual to determine the residence and choose the means of transportation. The analysis uses the data collected from people who live in Seoul metropolitan area including Seoul, Incheon and Gyeonggi Province, and commute to work and making the simple linkage travel (home-work-home) within the area. For the analysis, the Cox hazard proportional methodology was adopted. The method is known to be well applied without assuming any distribution in case of the dependent variable being continuous. For the covariate, the interaction effect between the space variable of the work place and the variable of transportation has been also included in the model. The commuting time to work has been estimated for both 1) the whole metropolitan area and 2) the separate regions i.e., Seoul, Incheon and Gyeonggi-Do. The result reveals that characteristic variables related to individual, household and travel properties influence the mode of transportation and the time allocated for commuting to work (p<0.01). This study also demonstrates the usefulness of the Cox hazard proportional model. The data used in this study is the actual household travel data surveyed in 2006 in the metropolitan area, and analyzing the survey data in 2010 is currently in progress. Comparison of the two survey data sets seeking any behavioral change is suggested for the future study.

• Communications for Statistical Applications and Methods
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• v.4 no.2
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• pp.435-444
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• 1997

The objective of this study is to investigate the problem of goodness of fit testing based on nonparametric function estimation techniques for the random censorship model. The small and large sample properties of the proposed test, $E_{mn}$, were investigated and it is shown that under the proportional hazard model $E_{mn}$ has higher power compared to the powers of the Kolmogorov -Smirnov, Kuiper, Cramer-von Mises, and analogue of the Cramer-von Mises type test statistic.

• Proceedings of the Korean Reliability Society Conference
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• 2005.06a
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• pp.121-129
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• 2005

In this paper, we consider a periodic preventive maintenance(PM) policy in which each PM reduces the hazard rate of amount proportional to the failure intensity, which increases since the last PM and slows down the wear-out speed to that of new one. And the proportion of reduction in hazard rate decreases with the number of PMs. Our model is similar to $ARI_1$ proposed by Doyen and Gaudoin(2004) in the sense of reduction of hazard rate. Our model has totally different wear-out pattern of hazard rate after PM's, however, and the proportion of reduction depends on the number of PM's. Assuming that the system undergoes only minimal repairs at failures between PM's, the expected cost rate per unit time is obtained. The optimal number N of PM and the optimal period x, which minimize the expected cost rate per unit time are discussed. Explicit solutions for the optimal periodic PM are given for the Weibull distribution case.

• Communications for Statistical Applications and Methods
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• v.9 no.2
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• pp.533-542
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• 2002

In this paper, a covariate adjusted logrank test is considered for censored paired data under the Cox proportional hazard model. The proposed score test resembles the adjusted logrank test of Tsiatis, Rosner and Tritchler (1985), which is derived from the partial likelihood. The dependence structure for paired data is accommodated into the test statistic by using' sum of square type' variance estimators. Several weight functions are also considered, which produce a class of covariate adjusted weighted logrank tests. Asymptotic normality of the proposed test is established and simulation studies with moderate sample size show the proposed test works well, particularly when there are dependence structure between treatment and covariates.

• Proceedings of the Korean Reliability Society Conference
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• 2005.06a
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• pp.265-269
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• 2005

Cox's proportional hazards model (PHM) has been widely applied in the analysis of lifetime data, and it can be characterized by the baseline hazard function and covariates influencing systems' lifetime, where the covariates describe operating environments (e.g. temperature, pressure, humidity). In this article, we consider the constant baseline hazard function and a discrete random variable of a covariate. The estimation procedure is developed in a parametric framework when there are not only complete data but also incomplete one. The Expectation-Maximization (EM) algorithm is employed to handle the incomplete data problem. Simulation results are presented to illustrate the accuracy and some properties of the estimation results.

• 한국데이터정보과학회:학술대회논문집
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• 2005.04a
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• pp.47-53
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• 2005